iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028316

Ensembl Protein ID

ENSDARP00000106434.1

UniProt Accession

Q7ZW33; Q6TGY5; UTP15_DANRE

Genbank Protein ID

AAQ97804.1; AAH45308.1

Protein Name

U3 small nucleolar RNA-associated protein 15 homolog

Genbank Nucleotide ID

AY398371; BC045308

Gene Name

utp15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000002720.8	ENSDART00000127397.2	ENSDARP00000106434.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-26	91.4	163	200
UBD/Beta-Prp	4.70e-42	145.1	41	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf....sdtllvsGsdDgtikvWDlrtgvll 36
           Htd ++++a     + + +v+Gs+D+t+k++D+r+g+++
   Q: 163  HTDYIRAIAPsklnP-DVFVTGSYDHTVKMFDVRSGNSV 200
           *********999633.99*****************9986 PP

UBD/Beta-Prp

   S: 13   itcvkf..spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
           +++++f   p  ++ +t+s   ++ ++ ++++  +r +    ++ +  +f  dgk+lv gse ++i+++d+  +  ++ +kgh++ v +
   Q: 41   VSKIDFspLPPHNYAVTAS--TRVHIYGLHSQEPIRNFTRFHDTAYGGSFRGDGKLLVAGSEEGLIRLFDIGGRVSLRQFKGHSKAVHA 127
           6778896678899999997..99***************99999********************************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls 187
           +sf  +g +++sGs+d t rvwd+ +  +l+   ++h++ ++ ++ ++ + +++v+Gs+D tv+++d+++g+ + t++  h ++v+++ 
   Q: 128  TSFLSDGFRVLSGSDDLTCRVWDVASAVELS-SITEHTDYIRAIAPSKLNpDVFVTGSYDHTVKMFDVRSGNSVMTMQ--HGQPVECVL 213
           *******************************.99*******************************************6..9******** PP
   S: 188  fdsngkelvsgsldgtvklwdl 209
           + ++ + l+     ++vk+wdl
   Q: 214  LYPS-EALLVSTGGRYVKVWDL 234
           ***6.5666667789******8 PP

Organism

Danio rerio

Functional Description
(View)

Involved in nucleolar processing of pre-18S ribosomal RNA.

Protein Sequence
(Fasta)

MASFKPTKVL SYPKLGEKVT EETLYWKNYK PPVQIKEFGA VSKIDFSPLP PHNYAVTAST 60
RVHIYGLHSQ EPIRNFTRFH DTAYGGSFRG DGKLLVAGSE EGLIRLFDIG GRVSLRQFKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAATATCGA TAAAGTTTGT TGAAAACCGG AAGTGTGGCG TCACAAAATG GCGGCCTCCA 60
TGTGGATGTA AAATCAACGT GAGTTTGCTC ATGTTTTCAA GTCTGATAAA AATCTTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR018983--U3_snoRNA-assocProt_15_C
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09384--UTP15_C
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0045766--P:positive regulation of angiogenesis
GO:0006364--P:rRNA processing

KEGG

dre:325106

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002117	Ailuropoda melanoleuca	58.42	6.00e-177	613.00
IUUC-Atr-003068	Amborella trichopoda	30.90	4.00e-61	229.00
IUUC-Apl-003926	Anas platyrhynchos	61.83	1.00e-170	592.00
IUUC-Aca-004271	Anolis carolinensis	61.60	0.00e+00	631.00
IUUC-Aly-005525	Arabidopsis lyrata	32.12	3.00e-59	223.00
IUUC-Ath-006954	Arabidopsis thaliana	31.70	4.00e-59	222.00
IUUC-Ago-007973	Ashbya gossypii	32.62	4.00e-68	252.00
IUUC-Acl-008287	Aspergillus clavatus	31.19	3.00e-49	189.00
IUUC-Afl-008504	Aspergillus flavus	29.78	2.00e-58	219.00
IUUC-Afu-008983	Aspergillus fumigatus	31.25	1.00e-43	171.00
IUUC-Ani-009315	Aspergillus nidulans	31.07	2.00e-53	203.00
IUUC-Ang-009690	Aspergillus niger	29.96	8.00e-57	214.00
IUUC-Aor-010181	Aspergillus oryzae	29.78	2.00e-58	219.00
IUUC-Ate-010498	Aspergillus terreus	30.27	7.00e-55	209.00
IUUC-Ame-011814	Astyanax mexicanus	77.22	0.00e+00	789.00
IUUC-Bgr-012273	Blumeria graminis	30.46	8.00e-64	238.00
IUUC-Bta-013068	Bos taurus	58.13	4.00e-176	611.00
IUUC-Bci-013930	Botrytis cinerea	30.87	2.00e-64	240.00
IUUC-Bdi-014876	Brachypodium distachyon	30.91	3.00e-63	236.00
IUUC-Bol-015366	Brassica oleracea	31.66	9.00e-65	241.00
IUUC-Bra-017589	Brassica rapa	30.94	2.00e-62	233.00
IUUC-Cel-018159	Caenorhabditis elegans	29.01	2.00e-54	207.00
IUUC-Cja-019139	Callithrix jacchus	58.13	6.00e-174	603.00
IUUC-Cfa-020742	Canis familiaris	56.15	4.00e-168	584.00
IUUC-Cpo-021707	Cavia porcellus	58.93	6.00e-178	617.00
IUUC-Cre-022665	Chlamydomonas reinhardtii	40.73	9.00e-89	320.00
IUUC-Csa-023024	Chlorocebus sabaeus	58.33	5.00e-177	613.00
IUUC-Cho-024487	Choloepus hoffmanni	64.49	2.00e-99	356.00
IUUC-Cin-025294	Ciona intestinalis	45.69	8.00e-132	463.00
IUUC-Cgl-026388	Colletotrichum gloeosporioides	30.53	3.00e-36	146.00
IUUC-Cne-026945	Cryptococcus neoformans	38.24	6.00e-84	305.00
IUUC-Cme-027108	Cyanidioschyzon merolae	31.62	1.00e-60	228.00
IUUC-Dno-028985	Dasypus novemcinctus	57.34	4.00e-173	601.00
IUUC-Dor-030219	Dipodomys ordii	46.86	1.00e-90	326.00
IUUC-Dse-031495	Dothistroma septosporum	28.66	2.00e-43	170.00
IUUC-Dme-031769	Drosophila melanogaster	38.31	6.00e-86	311.00
IUUC-Ete-032630	Echinops telfairi	65.51	2.00e-111	395.00
IUUC-Eca-033816	Equus caballus	58.28	4.00e-175	607.00
IUUC-Eeu-034840	Erinaceus europaeus	64.45	1.00e-94	340.00
IUUC-Fca-035751	Felis catus	57.94	1.00e-176	613.00
IUUC-Fal-036733	Ficedula albicollis	57.65	3.00e-180	624.00
IUUC-Fox-037743	Fusarium oxysporum	29.32	2.00e-55	210.00
IUUC-Fso-038395	Fusarium solani	30.45	2.00e-56	213.00
IUUC-Gmo-038803	Gadus morhua	64.74	0.00e+00	646.00
IUUC-Ggr-040092	Gaeumannomyces graminis	28.75	6.00e-55	208.00
IUUC-Gga-040714	Gallus gallus	61.20	0.00e+00	634.00
IUUC-Gac-042640	Gasterosteus aculeatus	63.33	0.00e+00	675.00
IUUC-Gma-044192	Glycine max	32.69	5.00e-62	232.00
IUUC-Ggo-045616	Gorilla gorilla	57.03	2.00e-174	605.00
IUUC-Hsa-046720	Homo sapiens	57.29	1.00e-163	569.00
IUUC-Itr-048796	Ictidomys tridecemlineatus	57.62	2.00e-173	602.00
IUUC-Kpa-049291	Komagataella pastoris	30.88	6.00e-63	234.00
IUUC-Lch-049729	Latimeria chalumnae	63.47	0.00e+00	646.00
IUUC-Lpe-051141	Leersia perrieri	31.47	2.00e-60	227.00
IUUC-Loc-051756	Lepisosteus oculatus	65.48	0.00e+00	703.00
IUUC-Lma-053083	Leptosphaeria maculans	29.46	1.00e-52	201.00
IUUC-Laf-054067	Loxodonta africana	58.75	5.00e-169	587.00
IUUC-Mcc-055096	Macaca mulatta	58.33	5.00e-177	613.00
IUUC-Meu-056604	Macropus eugenii	52.37	9.00e-152	530.00
IUUC-Mor-057186	Magnaporthe oryzae	30.00	1.00e-57	217.00
IUUC-Mtr-058346	Medicago truncatula	31.35	6.00e-59	221.00
IUUC-Mla-059116	Melampsora laricipopulina	34.38	1.00e-78	287.00
IUUC-Mga-060038	Meleagris gallopavo	57.78	7.00e-125	440.00
IUUC-Mvi-060272	Microbotryum violaceum	31.68	1.00e-70	260.00
IUUC-Mmr-060877	Microcebus murinus	57.82	6.00e-175	607.00
IUUC-Mdo-062168	Monodelphis domestica	57.82	1.00e-165	576.00
IUUC-Mmu-063441	Mus musculus	57.86	5.00e-173	600.00
IUUC-Mac-065330	Musa acuminata	32.49	4.00e-48	186.00
IUUC-Mpu-065704	Mustela putorius furo	58.33	5.00e-178	617.00
IUUC-Mlu-067640	Myotis lucifugus	58.28	2.00e-176	612.00
IUUC-Nfi-068589	Neosartorya fischeri	31.99	9.00e-45	174.00
IUUC-Ncr-068769	Neurospora crassa	33.82	2.00e-41	163.00
IUUC-Nle-069105	Nomascus leucogenys	55.95	1.00e-164	573.00
IUUC-Opr-070203	Ochotona princeps	58.81	0.00e+00	627.00
IUUC-Ont-072054	Oreochromis niloticus	67.19	0.00e+00	710.00
IUUC-Oan-073624	Ornithorhynchus anatinus	62.56	3.00e-163	568.00
IUUC-Ocu-074326	Oryctolagus cuniculus	57.14	2.00e-173	602.00
IUUC-Obr-076038	Oryza brachyantha	30.24	1.00e-54	207.00
IUUC-Ogl-077463	Oryza glaberrima	28.94	7.00e-53	201.00
IUUC-Ogu-078631	Oryza glumaepatula	29.02	1.00e-56	214.00
IUUC-Oin-079242	Oryza indica	29.13	5.00e-54	205.00
IUUC-Olo-080652	Oryza longistaminata	28.37	2.00e-49	190.00
IUUC-Ome-081109	Oryza meridionalis	30.04	8.00e-49	189.00
IUUC-Oni-082187	Oryza nivara	29.13	5.00e-54	205.00
IUUC-Opu-083995	Oryza punctata	30.15	8.00e-50	191.00
IUUC-Oru-084962	Oryza rufipogon	29.87	3.00e-49	189.00
IUUC-Osa-086201	Oryza sativa	29.87	3.00e-49	189.00
IUUC-Ola-087115	Oryzias latipes	64.13	0.00e+00	678.00
IUUC-Olu-087842	Ostreococcus lucimarinus	33.59	1.00e-69	257.00
IUUC-Oga-088204	Otolemur garnettii	57.54	1.00e-174	606.00
IUUC-Oar-089297	Ovis aries	58.02	4.00e-175	607.00
IUUC-Ptr-090953	Pan troglodytes	58.13	7.00e-176	610.00
IUUC-Pan-092451	Papio anubis	57.77	1.00e-174	606.00
IUUC-Psi-092999	Pelodiscus sinensis	63.20	0.00e+00	660.00
IUUC-Pma-094304	Petromyzon marinus	47.25	2.00e-134	472.00
IUUC-Pno-095060	Phaeosphaeria nodorum	30.23	8.00e-53	201.00
IUUC-Ppa-095433	Physcomitrella patens	35.85	4.00e-89	322.00
IUUC-Pfo-096433	Poecilia formosa	64.16	0.00e+00	665.00
IUUC-Pab-098677	Pongo abelii	57.94	5.00e-176	610.00
IUUC-Pop-099329	Populus trichocarpa	32.83	9.00e-57	214.00
IUUC-Pca-100444	Procavia capensis	66.20	1.00e-110	393.00
IUUC-Ppe-101318	Prunus persica	30.13	6.00e-69	254.00
IUUC-Pva-102162	Pteropus vampyrus	50.89	1.00e-152	533.00
IUUC-Pgr-103329	Puccinia graminis	32.44	5.00e-76	278.00
IUUC-Ptt-103837	Puccinia triticina	32.50	5.00e-77	281.00
IUUC-Pte-104133	Pyrenophora teres	29.69	8.00e-53	201.00
IUUC-Pyt-104675	Pyrenophora triticirepentis	29.50	1.00e-52	200.00
IUUC-Rno-105004	Rattus norvegicus	57.86	4.00e-173	601.00
IUUC-Sce-106443	Saccharomyces cerevisiae	31.78	2.00e-69	256.00
IUUC-Sha-107199	Sarcophilus harrisii	58.61	2.00e-176	612.00
IUUC-Sja-107670	Schizosaccharomyces japonicus	38.60	6.00e-94	338.00
IUUC-Spo-108125	Schizosaccharomyces pombe	38.21	6.00e-90	324.00
IUUC-Ssl-108534	Sclerotinia sclerotiorum	30.30	6.00e-64	238.00
IUUC-Smo-109588	Selaginella moellendorffii	38.22	2.00e-89	323.00
IUUC-Sit-110043	Setaria italica	29.17	2.00e-42	166.00
IUUC-Stu-112396	Solanum tuberosum	33.73	1.00e-76	280.00
IUUC-Sar-113359	Sorex araneus	55.14	1.00e-96	346.00
IUUC-Sre-114995	Sporisorium reilianum	34.44	3.00e-85	309.00
IUUC-Ssc-115397	Sus scrofa	58.53	1.00e-177	615.00
IUUC-Tgu-116834	Taeniopygia guttata	59.24	0.00e+00	637.00
IUUC-Tru-118764	Takifugu rubripes	66.80	0.00e+00	713.00
IUUC-Tsy-119118	Tarsius syrichta	57.74	1.00e-176	613.00
IUUC-Tni-120053	Tetraodon nigroviridis	64.82	0.00e+00	692.00
IUUC-Tca-121842	Theobroma cacao	33.04	2.00e-63	237.00
IUUC-Tre-122172	Trichoderma reesei	33.46	3.00e-63	236.00
IUUC-Tvi-122288	Trichoderma virens	31.45	9.00e-48	184.00
IUUC-Tae-124909	Triticum aestivum	29.98	2.00e-46	180.00
IUUC-Tur-126846	Triticum urartu	27.86	1.00e-27	117.00
IUUC-Tme-127164	Tuber melanosporum	33.13	1.00e-73	271.00
IUUC-Tbe-127458	Tupaia belangeri	58.86	3.00e-165	575.00
IUUC-Ttr-128680	Tursiops truncatus	58.22	2.00e-170	592.00
IUUC-Uma-129508	Ustilago maydis	34.81	1.00e-85	310.00
IUUC-Vda-129696	Verticillium dahliae	35.71	1.00e-46	181.00
IUUC-Vpa-130820	Vicugna pacos	57.06	1.00e-175	609.00
IUUC-Vvi-131126	Vitis vinifera	33.00	7.00e-76	278.00
IUUC-Xtr-131826	Xenopus tropicalis	60.16	0.00e+00	641.00
IUUC-Xma-133373	Xiphophorus maculatus	64.74	0.00e+00	674.00
IUUC-Yli-134432	Yarrowia lipolytica	31.26	2.00e-66	246.00
IUUC-Zma-135241	Zea mays	29.37	9.00e-54	204.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence