iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021755

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02053920

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008922.3	ENSCPOT00000009003.2	ENSCPOP00000008016.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.20e-103	346.2	419	757

Active Site

Position(s)	Description	Evidence
725	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 419  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 502
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++++dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++ipV
   Q: 503  RFPPCCYKKLLSPpivpgdqnipvgicSVTIDDLCQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKIPV 589
           *************666666666666555**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++e+d+++l++ t+y+g y +++ +i++Fw+v+ 
   Q: 590  TNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDG-YAKTDLTIRYFWDVVL 677
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 678  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 757
           *****************************...9999967777**************************************985 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

AAEEKKAKEL EREKLPPIVS AAAGATAGLD KGAKGQISTL SSVLSTVSQK KEAAENRSSP 60
THLILPNIKN GNVKEPVCLD VRQKQRISID ALSPEMKAPA FPEPVLPVQP KTMKDFQEDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCTGAAG AGAAGAAAGC GAAGGAGCTG GAGCGCGAGA AGCTGCCGCC CATCGTGTCC 60
GCCGCCGCCG GCGCGACCGC GGTAAGCACG GGCCGCGCGG GCGCCCCGAC GGCGACGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	94.69	0.00e+00	1431.00
IUUC-Apl-003589	Anas platyrhynchos	85.66	0.00e+00	1277.00
IUUC-Aca-004350	Anolis carolinensis	80.19	0.00e+00	1208.00
IUUC-Ago-007908	Ashbya gossypii	34.86	7.00e-80	291.00
IUUC-Acl-008288	Aspergillus clavatus	35.36	3.00e-96	347.00
IUUC-Afl-008402	Aspergillus flavus	34.00	7.00e-89	322.00
IUUC-Afu-008762	Aspergillus fumigatus	34.86	3.00e-93	337.00
IUUC-Ani-009176	Aspergillus nidulans	35.38	2.00e-91	330.00
IUUC-Ang-009791	Aspergillus niger	34.38	6.00e-91	329.00
IUUC-Aor-009921	Aspergillus oryzae	33.83	2.00e-88	320.00
IUUC-Ate-010295	Aspergillus terreus	35.66	1.00e-98	354.00
IUUC-Ame-010660	Astyanax mexicanus	82.61	9.00e-154	535.00
IUUC-Bgr-011981	Blumeria graminis	32.14	5.00e-91	329.00
IUUC-Bta-012945	Bos taurus	93.38	0.00e+00	1402.00
IUUC-Bci-013697	Botrytis cinerea	32.69	2.00e-78	287.00
IUUC-Cja-019263	Callithrix jacchus	92.74	0.00e+00	1399.00
IUUC-Cfa-020486	Canis familiaris	97.21	0.00e+00	1300.00
IUUC-Csa-023814	Chlorocebus sabaeus	93.30	0.00e+00	1334.00
IUUC-Cho-024980	Choloepus hoffmanni	77.03	0.00e+00	1114.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	42.20	1.00e-95	344.00
IUUC-Dre-028551	Danio rerio	74.83	0.00e+00	1144.00
IUUC-Dno-029497	Dasypus novemcinctus	92.41	0.00e+00	1261.00
IUUC-Dor-030867	Dipodomys ordii	81.62	0.00e+00	1188.00
IUUC-Dse-031239	Dothistroma septosporum	29.14	2.00e-88	321.00
IUUC-Ete-032902	Echinops telfairi	78.92	0.00e+00	1163.00
IUUC-Eca-033678	Equus caballus	94.11	0.00e+00	1399.00
IUUC-Eeu-035262	Erinaceus europaeus	78.45	0.00e+00	1048.00
IUUC-Fca-035590	Felis catus	94.66	0.00e+00	1431.00
IUUC-Fal-037123	Ficedula albicollis	81.18	0.00e+00	1236.00
IUUC-Fox-037941	Fusarium oxysporum	40.48	2.00e-99	357.00
IUUC-Fso-038388	Fusarium solani	41.27	3.00e-102	366.00
IUUC-Gmo-039553	Gadus morhua	67.08	0.00e+00	853.00
IUUC-Ggr-040110	Gaeumannomyces graminis	32.79	5.00e-97	349.00
IUUC-Gga-040406	Gallus gallus	84.76	0.00e+00	1316.00
IUUC-Gac-042141	Gasterosteus aculeatus	76.97	0.00e+00	1112.00
IUUC-Ggo-045504	Gorilla gorilla	92.50	0.00e+00	1407.00
IUUC-Hsa-045786	Homo sapiens	93.00	0.00e+00	1412.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	89.47	0.00e+00	1229.00
IUUC-Kpa-049152	Komagataella pastoris	33.78	3.00e-75	276.00
IUUC-Lch-049824	Latimeria chalumnae	81.04	0.00e+00	1096.00
IUUC-Loc-052173	Lepisosteus oculatus	78.15	0.00e+00	1189.00
IUUC-Laf-054017	Loxodonta africana	95.89	0.00e+00	1336.00
IUUC-Mcc-055713	Macaca mulatta	93.01	0.00e+00	1392.00
IUUC-Meu-056212	Macropus eugenii	70.68	3.00e-118	419.00
IUUC-Mor-057045	Magnaporthe oryzae	38.51	6.00e-89	322.00
IUUC-Mla-059187	Melampsora laricipopulina	43.74	3.00e-87	315.00
IUUC-Mga-059884	Meleagris gallopavo	78.83	0.00e+00	1152.00
IUUC-Mmr-061344	Microcebus murinus	94.10	0.00e+00	1399.00
IUUC-Mdo-062653	Monodelphis domestica	87.85	0.00e+00	1324.00
IUUC-Mmu-063775	Mus musculus	90.24	0.00e+00	1291.00
IUUC-Mpu-066069	Mustela putorius furo	96.98	0.00e+00	1330.00
IUUC-Mlu-067925	Myotis lucifugus	93.56	0.00e+00	1374.00
IUUC-Nfi-068439	Neosartorya fischeri	34.86	4.00e-93	336.00
IUUC-Ncr-068903	Neurospora crassa	37.88	1.00e-90	328.00
IUUC-Nle-070046	Nomascus leucogenys	92.90	0.00e+00	1422.00
IUUC-Opr-071085	Ochotona princeps	80.20	2.00e-138	486.00
IUUC-Ont-072126	Oreochromis niloticus	73.34	0.00e+00	1164.00
IUUC-Oan-072933	Ornithorhynchus anatinus	89.03	0.00e+00	1176.00
IUUC-Ocu-073800	Oryctolagus cuniculus	96.53	0.00e+00	1302.00
IUUC-Ola-086988	Oryzias latipes	77.16	0.00e+00	1120.00
IUUC-Oga-088117	Otolemur garnettii	96.55	0.00e+00	1132.00
IUUC-Oar-089371	Ovis aries	93.42	0.00e+00	1368.00
IUUC-Ptr-090551	Pan troglodytes	92.24	0.00e+00	1360.00
IUUC-Pan-092067	Papio anubis	93.51	0.00e+00	1397.00
IUUC-Psi-092963	Pelodiscus sinensis	84.93	0.00e+00	1261.00
IUUC-Pfo-096562	Poecilia formosa	71.09	0.00e+00	1122.00
IUUC-Pab-098680	Pongo abelii	93.14	0.00e+00	1414.00
IUUC-Pca-100986	Procavia capensis	76.00	0.00e+00	895.00
IUUC-Pva-102219	Pteropus vampyrus	78.71	0.00e+00	1069.00
IUUC-Pgr-103315	Puccinia graminis	36.57	6.00e-96	345.00
IUUC-Ptt-103736	Puccinia triticina	41.91	1.00e-94	340.00
IUUC-Rno-105270	Rattus norvegicus	89.07	0.00e+00	1295.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.65	1.00e-68	254.00
IUUC-Sha-106819	Sarcophilus harrisii	89.73	0.00e+00	1353.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.63	2.00e-85	310.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	31.23	1.00e-83	305.00
IUUC-Sar-113134	Sorex araneus	84.38	0.00e+00	1213.00
IUUC-Ssc-115441	Sus scrofa	93.93	0.00e+00	1381.00
IUUC-Tgu-117166	Taeniopygia guttata	84.39	0.00e+00	1257.00
IUUC-Tsy-118898	Tarsius syrichta	81.72	0.00e+00	1126.00
IUUC-Tre-122108	Trichoderma reesei	38.95	8.00e-89	322.00
IUUC-Tvi-122644	Trichoderma virens	39.11	3.00e-94	340.00
IUUC-Tme-127004	Tuber melanosporum	34.71	4.00e-101	363.00
IUUC-Tbe-127292	Tupaia belangeri	77.95	0.00e+00	1068.00
IUUC-Ttr-128352	Tursiops truncatus	90.14	0.00e+00	1323.00
IUUC-Vda-129969	Verticillium dahliae	40.22	4.00e-92	333.00
IUUC-Vpa-130218	Vicugna pacos	91.28	0.00e+00	986.00
IUUC-Xtr-132594	Xenopus tropicalis	77.87	0.00e+00	1174.00
IUUC-Xma-134157	Xiphophorus maculatus	75.74	0.00e+00	1039.00
IUUC-Yli-134470	Yarrowia lipolytica	35.56	4.00e-76	279.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence