iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fox-037941

Ensembl Protein ID

FOXG_08021P0

UniProt Accession

A0A0D2XVK9; A0A0D2XVK9_FUSO4

Genbank Protein ID

KNB05879.1

Protein Name

Other hect domain ubiquitin protein ligase E3

Genbank Nucleotide ID

DS231703

Gene Name

FOXG_08021

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FOXG_08021	FOXG_08021T0	FOXG_08021P0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.10e-82	275.4	869	1213

Active Site

Position(s)	Description	Evidence
1182	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfy 97
           +d+kk l+++f+gEeg+d+gG+ +e++ ll++e++npd glfly+e+++++ + np+++    e  + F ++G+++g+a++++ +ld+ l+++ +
   Q: 869  EDIKKGLRITFSGEEGVDAGGLRKEWFLLLAREVFNPDHGLFLYDEDSQYC-YFNPNAF----ETSDQFFLVGVVMGLAIYNSTILDVALPPFAF 958
           6899******************************************99998.6699998....6889999************************* PP
   S: 98   klllgk................klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvkl 176
           ++l+                  +++ledl+e  p l++ l +++e+ e ++e++ ++l f ++ +++g++ ++ L+pgGe+ipVtn+N++eYv+l
   Q: 959  RKLIASapthgtgasahprppmRYTLEDLAEYRPRLARGLRQLLEY-EGNVEDT-FCLDFVIDMDKYGTQVQVPLCPGGERIPVTNSNRREYVDL 1051
           **9888777777777777777779**********************.7899998.**************************************** PP
   S: 177  vveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky....kggytedspaiqwFwevleefsseerkafLq 266
           +v y++  ++++q+e f++Gf++v+  + lslF++ee+ell+ G+ e +d+++l+  ++y    ++    ++p+i+wFwe++++ +s++++++L 
   Q: 1052 YVRYIIDVSVTRQFEPFKRGFYTVCGGNALSLFRPEEIELLVRGSdEALDINSLRGVAEYdnwgTKKPDGSEPVIDWFWETFQAATSQDQRKLLL 1146
           *********************************************999************766655567799*********************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           F+Tgs+r+P+ G a l+ ++ ++ +  ++ r+P + TCfn+L L +Y+ske l++ L +A++e++gF+ 
   Q: 1147 FITGSDRIPAMGAAVLPIKISCLGE--DEGRFPIARTCFNVLSLSRYKSKERLEKLLWTAVHESEGFGI 1213
           *****************77777666..88**************************************85 PP

Organism

Fusarium oxysporum

Protein Sequence
(Fasta)

MAPWSSRRGS QPNNNSNGDL ISRIHNTALH TPTTLPALYS TNLPNTSNGN RLELSFSNAN 60
ADSSSDESDL HPSRPQSSKP RRPQHTRSMS QPFPSLFSSK KKRQNSVGAP PPDLGFADDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATCCAATC CTAAATATCT TTACTCATCA GCACTACCTA TACGTGCAAA CCGGGCTTGT 60
TTCACCAACC ACAGCCACGG CTTGAGCTGC ACCCATCACT CATCGTTCAT TGCTTTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	40.68	1.00e-103	369.00
IUUC-Atr-003144	Amborella trichopoda	36.65	4.00e-83	300.00
IUUC-Apl-003589	Anas platyrhynchos	40.19	2.00e-96	344.00
IUUC-Aca-004350	Anolis carolinensis	41.76	1.00e-99	355.00
IUUC-Ago-007908	Ashbya gossypii	30.79	7.00e-94	336.00
IUUC-Acl-008288	Aspergillus clavatus	49.61	0.00e+00	855.00
IUUC-Afl-008402	Aspergillus flavus	57.04	0.00e+00	735.00
IUUC-Afu-008762	Aspergillus fumigatus	44.69	0.00e+00	957.00
IUUC-Ani-009176	Aspergillus nidulans	40.87	0.00e+00	759.00
IUUC-Ang-009791	Aspergillus niger	45.44	0.00e+00	863.00
IUUC-Aor-009921	Aspergillus oryzae	60.03	0.00e+00	706.00
IUUC-Ame-011166	Astyanax mexicanus	38.51	1.00e-89	322.00
IUUC-Bgr-011981	Blumeria graminis	48.12	0.00e+00	1014.00
IUUC-Bta-012945	Bos taurus	41.70	5.00e-102	363.00
IUUC-Bci-013697	Botrytis cinerea	54.08	0.00e+00	888.00
IUUC-Cel-018150	Caenorhabditis elegans	30.79	3.00e-56	211.00
IUUC-Cja-019263	Callithrix jacchus	41.05	5.00e-99	353.00
IUUC-Cfa-020486	Canis familiaris	41.08	2.00e-103	368.00
IUUC-Cpo-021755	Cavia porcellus	40.48	9.00e-104	369.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	39.53	7.00e-59	218.00
IUUC-Csa-023378	Chlorocebus sabaeus	39.06	5.00e-88	317.00
IUUC-Cho-025059	Choloepus hoffmanni	36.57	3.00e-77	281.00
IUUC-Cin-025643	Ciona intestinalis	37.80	9.00e-75	273.00
IUUC-Csv-026282	Ciona savignyi	36.67	6.00e-67	247.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	56.02	0.00e+00	1181.00
IUUC-Cme-027151	Cyanidioschyzon merolae	37.80	5.00e-83	300.00
IUUC-Dre-028551	Danio rerio	41.91	3.00e-99	354.00
IUUC-Dno-029497	Dasypus novemcinctus	40.92	1.00e-99	355.00
IUUC-Dor-030158	Dipodomys ordii	34.95	3.00e-75	275.00
IUUC-Dse-031239	Dothistroma septosporum	45.94	0.00e+00	799.00
IUUC-Dme-032103	Drosophila melanogaster	35.62	7.00e-71	260.00
IUUC-Ete-032902	Echinops telfairi	37.07	3.00e-91	327.00
IUUC-Eca-033678	Equus caballus	40.68	9.00e-104	369.00
IUUC-Eeu-035109	Erinaceus europaeus	37.47	1.00e-78	285.00
IUUC-Fca-035590	Felis catus	40.48	5.00e-104	370.00
IUUC-Fal-036747	Ficedula albicollis	39.13	6.00e-89	320.00
IUUC-Fso-038388	Fusarium solani	77.51	0.00e+00	1831.00
IUUC-Gmo-039553	Gadus morhua	40.18	1.00e-85	308.00
IUUC-Ggr-040110	Gaeumannomyces graminis	51.00	0.00e+00	1078.00
IUUC-Gga-040406	Gallus gallus	40.50	2.00e-100	357.00
IUUC-Gac-042141	Gasterosteus aculeatus	38.88	2.00e-97	348.00
IUUC-Ggo-045504	Gorilla gorilla	40.83	2.00e-99	354.00
IUUC-Hsa-045786	Homo sapiens	40.83	2.00e-99	355.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	38.72	3.00e-85	307.00
IUUC-Kpa-049152	Komagataella pastoris	33.42	2.00e-97	348.00
IUUC-Lch-050197	Latimeria chalumnae	39.06	2.00e-91	328.00
IUUC-Loc-052173	Lepisosteus oculatus	39.65	5.00e-103	366.00
IUUC-Laf-054017	Loxodonta africana	41.09	2.00e-100	358.00
IUUC-Mcc-055713	Macaca mulatta	41.05	2.00e-99	355.00
IUUC-Meu-056061	Macropus eugenii	38.83	7.00e-86	310.00
IUUC-Mor-057045	Magnaporthe oryzae	51.14	0.00e+00	1098.00
IUUC-Mla-059187	Melampsora laricipopulina	41.97	7.00e-95	338.00
IUUC-Mga-059271	Meleagris gallopavo	39.13	2.00e-88	318.00
IUUC-Mmr-061344	Microcebus murinus	41.08	7.00e-105	373.00
IUUC-Mdo-062653	Monodelphis domestica	42.36	2.00e-101	361.00
IUUC-Mmu-063775	Mus musculus	42.48	3.00e-103	367.00
IUUC-Mpu-066069	Mustela putorius furo	40.68	1.00e-103	368.00
IUUC-Mlu-067925	Myotis lucifugus	42.58	8.00e-103	366.00
IUUC-Nfi-068439	Neosartorya fischeri	48.70	0.00e+00	869.00
IUUC-Ncr-068903	Neurospora crassa	51.34	0.00e+00	1046.00
IUUC-Nle-070046	Nomascus leucogenys	39.28	8.00e-101	359.00
IUUC-Opr-070570	Ochotona princeps	34.37	9.00e-68	249.00
IUUC-Ont-072126	Oreochromis niloticus	38.12	3.00e-97	347.00
IUUC-Oan-072933	Ornithorhynchus anatinus	41.85	3.00e-99	353.00
IUUC-Ocu-073800	Oryctolagus cuniculus	41.05	3.00e-99	354.00
IUUC-Ola-086988	Oryzias latipes	40.00	2.00e-98	351.00
IUUC-Oga-088117	Otolemur garnettii	41.48	2.00e-100	357.00
IUUC-Oar-089371	Ovis aries	41.70	1.00e-101	362.00
IUUC-Ptr-090551	Pan troglodytes	40.83	1.00e-99	355.00
IUUC-Pan-092067	Papio anubis	41.05	2.00e-99	355.00
IUUC-Psi-092963	Pelodiscus sinensis	42.42	2.00e-99	355.00
IUUC-Pma-094643	Petromyzon marinus	40.18	9.00e-88	316.00
IUUC-Ppa-095354	Physcomitrella patens	40.04	7.00e-93	333.00
IUUC-Pfo-096562	Poecilia formosa	37.50	8.00e-96	343.00
IUUC-Pab-098680	Pongo abelii	40.83	2.00e-99	354.00
IUUC-Pca-100869	Procavia capensis	38.10	2.00e-85	308.00
IUUC-Pva-102219	Pteropus vampyrus	38.83	2.00e-80	291.00
IUUC-Pgr-103315	Puccinia graminis	43.42	5.00e-103	367.00
IUUC-Ptt-103736	Puccinia triticina	42.89	6.00e-103	367.00
IUUC-Rno-105270	Rattus norvegicus	42.36	3.00e-103	367.00
IUUC-Sce-106306	Saccharomyces cerevisiae	36.76	3.00e-84	304.00
IUUC-Sha-106819	Sarcophilus harrisii	40.74	2.00e-104	371.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	35.64	3.00e-57	214.00
IUUC-Spo-108271	Schizosaccharomyces pombe	35.65	7.00e-107	379.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	48.30	0.00e+00	1001.00
IUUC-Smo-108858	Selaginella moellendorffii	41.02	8.00e-87	312.00
IUUC-Sar-113293	Sorex araneus	38.51	1.00e-86	313.00
IUUC-Ssc-115441	Sus scrofa	41.83	4.00e-102	363.00
IUUC-Tgu-117166	Taeniopygia guttata	40.70	3.00e-96	344.00
IUUC-Tru-118368	Takifugu rubripes	38.45	3.00e-87	314.00
IUUC-Tsy-118898	Tarsius syrichta	35.73	2.00e-78	285.00
IUUC-Tni-120143	Tetraodon nigroviridis	38.45	1.00e-86	313.00
IUUC-Tre-122108	Trichoderma reesei	56.45	0.00e+00	1210.00
IUUC-Tvi-122644	Trichoderma virens	56.09	0.00e+00	1236.00
IUUC-Tme-127004	Tuber melanosporum	45.34	0.00e+00	766.00
IUUC-Tbe-127640	Tupaia belangeri	38.88	9.00e-71	260.00
IUUC-Ttr-128352	Tursiops truncatus	39.52	1.00e-92	332.00
IUUC-Vda-129969	Verticillium dahliae	55.85	0.00e+00	1136.00
IUUC-Vpa-130448	Vicugna pacos	35.37	2.00e-75	275.00
IUUC-Xtr-132881	Xenopus tropicalis	38.51	5.00e-93	333.00
IUUC-Xma-133122	Xiphophorus maculatus	37.63	3.00e-87	315.00
IUUC-Yli-134470	Yarrowia lipolytica	39.35	1.00e-100	359.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence