iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118042

UUCD1 version

UUC-TaR-01098

Ensembl Protein ID

ENSTRUP00000003439.1

UniProt Accession

H2RTH2; H2RTH2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

zranb1b; LOC101077697

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000001497.1	ENSTRUT00000003458.1	ENSTRUP00000003439.1
ENSTRUG00000001497.1	ENSTRUT00000003459.1	ENSTRUP00000003440.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	3.30e-35	122.7	480	640
UBD/ZnF/NZF	1.60e-28	99.1	6	32

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 1    llilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseyl....qkesdffsefieek........edekefcqklvepeak 76
           l++l+++++G+CLl++v q+++g++d+ds l++ l+++L++ +s+++    +++++++s+++  +        +++++f+ +l+++++ 
   Q: 480  LYALWNRTAGDCLLDSVLQATWGIYDKDSvLRKTLHDSLHD-CSHWFytrwKEWESWYSQSFGLHfslreeqwQEDWAFILSLASQPGS 567
           6899*************************************.*****999999999999999999**********************88 PP
   S: 77   .geeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYdaLval 138
             e++hif+La+iL+rpiiv+ v++++s         +++g++lpll++++  +k+pi+L+Y++gH++aLva+
   Q: 568  sLEQTHIFVLAHILRRPIIVYGVKYYKSfrgetlgytRFQGVYLPLLWEQSFcWKSPIALGYTRGHFSALVAM 640
           56********************************************************************986 PP

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
           a+WaC++CT++N+P+a+kC+mC  +R+
   Q: 6    AKWACEYCTYENWPSAIKCTMCRAQRP 32
           79************************8 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MTELVAKWAC EYCTYENWPS AIKCTMCRAQ RPSGGAIITE EPFKSSPALD ASLHISADLS 60
NSPSQGGSSL LICPDSSARP RVRIADVPEI SSKWSCHMCT YLNWPRAIRC TQCLCQRQHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCGAAC TGGTTGCCAA GTGGGCCTGT GAATACTGCA CATACGAGAA CTGGCCGTCG 60
GCCATCAAGT GCACCATGTG TCGCGCTCAG AGGCCCAGCG GGGGTGCCAT CATCACCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR001876--Znf_RanBP2

PROSITE

PS50802--OTU
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02338--OTU
PF00641--zf-RanBP

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0016477--P:cell migration
GO:0021551--P:central nervous system morphogenesis
GO:0007010--P:cytoskeleton organization
GO:0030177--P:positive regulation of Wnt signaling pathway
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035523--P:protein K29-linked deubiquitination
GO:1990168--P:protein K33-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008658	Aspergillus flavus	33.80	3.00e-03	36.20
IUUC-Aor-009946	Aspergillus oryzae	33.80	3.00e-03	36.20
IUUC-Ame-011865	Astyanax mexicanus	77.70	0.00e+00	1155.00
IUUC-Dre-028575	Danio rerio	77.94	0.00e+00	1164.00
IUUC-Gmo-038762	Gadus morhua	86.80	0.00e+00	1266.00
IUUC-Gac-042178	Gasterosteus aculeatus	91.20	0.00e+00	1359.00
IUUC-Nfi-068513	Neosartorya fischeri	35.19	6.00e-03	35.40
IUUC-Ont-071506	Oreochromis niloticus	90.49	0.00e+00	1364.00
IUUC-Oan-072942	Ornithorhynchus anatinus	93.79	6.00e-161	559.00
IUUC-Ola-087151	Oryzias latipes	89.84	0.00e+00	1328.00
IUUC-Pfo-096771	Poecilia formosa	91.50	0.00e+00	1345.00
IUUC-Pgr-103642	Puccinia graminis	24.03	6.00e-04	38.90
IUUC-Tni-120502	Tetraodon nigroviridis	88.22	0.00e+00	724.00
IUUC-Tbe-127522	Tupaia belangeri	93.65	0.00e+00	825.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence