iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097788

Ensembl Protein ID

ENSPPYP00000009814.1

UniProt Accession

H2NV23; H2NV23_PONAB

Genbank Protein ID

ENSPPYP00000009814

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01289512

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000008743.1	ENSPPYT00000010205.1	ENSPPYP00000009814.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	1.00e-51	174.5	15	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icdli++ +++ak+a+++++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel++llk+++e++
   Q: 15   ATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVN 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
           ***************************************8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MGRGSGTFER LLDKATSQLL LETDWESILQ ICDLIRQGDT QAKYAVNSIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKDLLKRQV EVNVRNKILY LIQAWAHAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGGTA ACGCGTCCCC ACCCGACGGC 60
CCGGCCTTGG TCAGCCCGCA GCCTCCGCCC GGCGCTGAGT CAGCGCGGCC CCAAGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	90.29	0.00e+00	708.00
IUUC-Apl-003662	Anas platyrhynchos	82.01	0.00e+00	730.00
IUUC-Aca-004940	Anolis carolinensis	86.32	0.00e+00	800.00
IUUC-Ago-007931	Ashbya gossypii	30.43	1.00e-26	114.00
IUUC-Acl-008274	Aspergillus clavatus	31.41	3.00e-40	159.00
IUUC-Afl-008521	Aspergillus flavus	33.98	7.00e-41	162.00
IUUC-Afu-008774	Aspergillus fumigatus	33.33	6.00e-41	162.00
IUUC-Ani-009445	Aspergillus nidulans	32.96	2.00e-41	164.00
IUUC-Ang-009863	Aspergillus niger	34.30	1.00e-42	167.00
IUUC-Ate-010444	Aspergillus terreus	35.53	6.00e-43	168.00
IUUC-Ame-011111	Astyanax mexicanus	81.17	0.00e+00	738.00
IUUC-Bgr-012087	Blumeria graminis	33.57	7.00e-43	168.00
IUUC-Bta-012506	Bos taurus	93.40	0.00e+00	826.00
IUUC-Bci-013782	Botrytis cinerea	34.57	1.00e-41	164.00
IUUC-Cel-018493	Caenorhabditis elegans	52.61	6.00e-68	251.00
IUUC-Cja-019998	Callithrix jacchus	94.87	0.00e+00	818.00
IUUC-Cfa-020615	Canis familiaris	91.98	0.00e+00	775.00
IUUC-Cpo-022019	Cavia porcellus	95.07	0.00e+00	850.00
IUUC-Csa-023596	Chlorocebus sabaeus	98.72	0.00e+00	842.00
IUUC-Cin-025488	Ciona intestinalis	43.64	4.00e-103	369.00
IUUC-Csv-025802	Ciona savignyi	45.32	6.00e-93	334.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	35.42	4.00e-40	159.00
IUUC-Cne-026847	Cryptococcus neoformans	31.89	4.00e-38	153.00
IUUC-Dre-028353	Danio rerio	78.70	0.00e+00	739.00
IUUC-Dno-029005	Dasypus novemcinctus	90.21	0.00e+00	807.00
IUUC-Dor-030280	Dipodomys ordii	94.61	0.00e+00	838.00
IUUC-Dse-031238	Dothistroma septosporum	38.71	2.00e-42	167.00
IUUC-Dme-031952	Drosophila melanogaster	48.24	1.00e-78	287.00
IUUC-Ete-032235	Echinops telfairi	96.36	9.00e-132	464.00
IUUC-Eca-033873	Equus caballus	94.52	0.00e+00	820.00
IUUC-Eeu-034652	Erinaceus europaeus	95.53	3.00e-104	372.00
IUUC-Fca-036563	Felis catus	90.66	0.00e+00	773.00
IUUC-Fal-036649	Ficedula albicollis	86.04	0.00e+00	732.00
IUUC-Fox-037962	Fusarium oxysporum	32.86	2.00e-39	157.00
IUUC-Fso-038396	Fusarium solani	33.57	4.00e-40	159.00
IUUC-Gmo-039510	Gadus morhua	80.67	0.00e+00	712.00
IUUC-Ggr-039938	Gaeumannomyces graminis	31.91	1.00e-37	151.00
IUUC-Gga-040201	Gallus gallus	86.38	0.00e+00	789.00
IUUC-Gac-041459	Gasterosteus aculeatus	79.21	0.00e+00	713.00
IUUC-Ggo-044573	Gorilla gorilla	100.00	0.00e+00	884.00
IUUC-Hsa-046009	Homo sapiens	99.79	0.00e+00	885.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	94.65	0.00e+00	865.00
IUUC-Kpa-049327	Komagataella pastoris	30.13	1.00e-32	134.00
IUUC-Lch-050236	Latimeria chalumnae	80.28	4.00e-100	357.00
IUUC-Loc-051850	Lepisosteus oculatus	82.22	0.00e+00	736.00
IUUC-Lma-053252	Leptosphaeria maculans	35.65	7.00e-41	162.00
IUUC-Laf-053346	Loxodonta africana	92.55	0.00e+00	791.00
IUUC-Mcc-055789	Macaca mulatta	99.36	0.00e+00	841.00
IUUC-Meu-056329	Macropus eugenii	86.82	1.00e-113	404.00
IUUC-Mor-057205	Magnaporthe oryzae	33.56	1.00e-38	154.00
IUUC-Mpo-057295	Magnaporthe poae	31.56	4.00e-39	156.00
IUUC-Mla-058849	Melampsora laricipopulina	33.03	8.00e-32	132.00
IUUC-Mga-059361	Meleagris gallopavo	85.62	0.00e+00	753.00
IUUC-Mvi-060561	Microbotryum violaceum	32.95	7.00e-40	158.00
IUUC-Mmr-061122	Microcebus murinus	94.47	0.00e+00	838.00
IUUC-Mdo-062171	Monodelphis domestica	92.08	0.00e+00	840.00
IUUC-Mmu-063952	Mus musculus	94.86	0.00e+00	865.00
IUUC-Mpu-065852	Mustela putorius furo	91.95	0.00e+00	780.00
IUUC-Mlu-066996	Myotis lucifugus	86.71	7.00e-65	241.00
IUUC-Nfi-068539	Neosartorya fischeri	32.96	4.00e-41	162.00
IUUC-Ncr-068726	Neurospora crassa	39.17	7.00e-40	158.00
IUUC-Nle-070148	Nomascus leucogenys	95.07	0.00e+00	816.00
IUUC-Opr-070833	Ochotona princeps	79.19	3.00e-160	558.00
IUUC-Ont-071261	Oreochromis niloticus	80.21	0.00e+00	723.00
IUUC-Oan-073684	Ornithorhynchus anatinus	70.81	1.00e-154	539.00
IUUC-Ola-087570	Oryzias latipes	77.53	0.00e+00	691.00
IUUC-Oga-089087	Otolemur garnettii	88.25	0.00e+00	763.00
IUUC-Oar-089534	Ovis aries	92.98	0.00e+00	822.00
IUUC-Ptr-091654	Pan troglodytes	91.01	0.00e+00	774.00
IUUC-Pan-092652	Papio anubis	99.36	0.00e+00	843.00
IUUC-Pno-095125	Phaeosphaeria nodorum	37.39	3.00e-42	166.00
IUUC-Pfo-096757	Poecilia formosa	80.50	0.00e+00	731.00
IUUC-Pca-100145	Procavia capensis	74.26	5.00e-169	588.00
IUUC-Pva-102965	Pteropus vampyrus	92.77	0.00e+00	819.00
IUUC-Pgr-103609	Puccinia graminis	34.69	2.00e-33	136.00
IUUC-Ptt-103865	Puccinia triticina	35.71	5.00e-34	139.00
IUUC-Pte-104095	Pyrenophora teres	32.50	1.00e-41	164.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	32.97	4.00e-41	163.00
IUUC-Rno-105125	Rattus norvegicus	94.25	0.00e+00	803.00
IUUC-Sce-106192	Saccharomyces cerevisiae	28.77	2.00e-26	114.00
IUUC-Sha-107066	Sarcophilus harrisii	91.91	0.00e+00	850.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	33.52	8.00e-42	165.00
IUUC-Spo-108220	Schizosaccharomyces pombe	36.28	2.00e-36	147.00
IUUC-Stu-112464	Solanum tuberosum	33.98	6.00e-13	70.10
IUUC-Sar-113393	Sorex araneus	91.58	2.00e-105	376.00
IUUC-Sre-114986	Sporisorium reilianum	37.78	2.00e-42	167.00
IUUC-Tgu-117505	Taeniopygia guttata	87.55	0.00e+00	778.00
IUUC-Tru-118494	Takifugu rubripes	80.17	0.00e+00	733.00
IUUC-Tsy-119626	Tarsius syrichta	100.00	5.00e-54	205.00
IUUC-Tni-120174	Tetraodon nigroviridis	79.66	0.00e+00	710.00
IUUC-Tre-122191	Trichoderma reesei	33.82	2.00e-40	160.00
IUUC-Tvi-122318	Trichoderma virens	32.87	1.00e-41	164.00
IUUC-Tme-126914	Tuber melanosporum	34.40	8.00e-44	171.00
IUUC-Ttr-129095	Tursiops truncatus	94.43	0.00e+00	836.00
IUUC-Uma-129475	Ustilago maydis	36.28	4.00e-39	156.00
IUUC-Vda-129908	Verticillium dahliae	32.84	2.00e-35	143.00
IUUC-Xtr-131900	Xenopus tropicalis	83.12	0.00e+00	770.00
IUUC-Xma-133124	Xiphophorus maculatus	80.38	0.00e+00	727.00
IUUC-Yli-134682	Yarrowia lipolytica	35.27	2.00e-32	134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence