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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105289
UUCD1 version UUC-RaN-00405
Ensembl Protein ID ENSRNOP00000050012.3
UniProt Accession D3ZJB8; D3ZJB8_RAT
Genbank Protein ID EDL77153.1
Protein Name Ariadne RBR E3 ubiquitin protein ligase 2; Ariadne homolog 2 (Drosophila) (Predicted), isoform CRA_a
Genbank Nucleotide ID AC107280
Gene Name Arih2; Arih2_predicted; rCG_25280
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000031827.4 ENSRNOT00000042577.4 ENSRNOP00000050012.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFACmiRNAMapRAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RBR 7.90e-56 189.7 138 325
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RBR
   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC+ ++  +e++ +l+C+h+fC++C++q++++ +k+g  + isc+a++cp +++e+ +  ll++eel ++y+++l++++ve++++l++
   Q: 138  CAVCM-QFVRKENLLSLTCQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFVFPLLPNEELRDKYRRYLFRDYVESHYQLQL 226
           9***9.77777888899************************************************************************* PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp +dC +v+++++  ++ +v+c++c+++fC++C++++H++++C +++++l+k++   +++e++++++a++k+CpkC+++iekn+gCnhm
   Q: 227  CPGADCPMVIRVQEP-RARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA---DDSETANYISAHTKDCPKCNICIEKNGGCNHM 312
           **************7.99*************************************...99****************************** PP
   S: 181  tCakCkaefCwlC 193
           +C+kCk++fCw+C
   Q: 313  QCSKCKHDFCWMC 325
           ************* PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MSVDMNSQGS DSNEEDYDPN CEEEEEEEED PGDIEDYYVG VASDVEQQGA DAFDPEEYQF 60
TCLTYKESEG ALHEHMTSLA SALKVSHSVA KLILVNFHWQ VSEILDRYRS NSAQLLVEAR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105289|E3,RBR|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGCCGCGA GGTCGCGGCT CCCGGTAAGT GCGCGGCGTG AGTCGAGGCC TTGTTTACTC 60
TTGACTGGCC TCGGGGGGGG GGATCCCCGC GCGCCTCTCC GGCGCGGTCG GGGCTCCGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105289|E3,RBR|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF01485--IBR
SMART

SM00647--IBR
SM00184--RING
Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0048588--P:developmental cell growth
GO:0071425--P:hematopoietic stem cell proliferation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG rno:316005
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001557 Ailuropoda melanoleuca 97.76 0.00e+00 934.00
IUUC-Apl-003878 Anas platyrhynchos 92.68 0.00e+00 873.00
IUUC-Aca-004865 Anolis carolinensis 92.48 0.00e+00 882.00
IUUC-Bta-012901 Bos taurus 97.56 0.00e+00 929.00
IUUC-Cel-018334 Caenorhabditis elegans 49.32 8.00e-128 450.00
IUUC-Cja-019728 Callithrix jacchus 98.17 0.00e+00 935.00
IUUC-Cfa-020953 Canis familiaris 97.97 0.00e+00 934.00
IUUC-Cpo-021445 Cavia porcellus 98.37 0.00e+00 937.00
IUUC-Csa-023769 Chlorocebus sabaeus 96.35 0.00e+00 931.00
IUUC-Cho-024650 Choloepus hoffmanni 86.41 0.00e+00 788.00
IUUC-Cin-025577 Ciona intestinalis 54.09 4.00e-143 501.00
IUUC-Csv-025849 Ciona savignyi 56.10 6.00e-120 424.00
IUUC-Dre-028490 Danio rerio 80.20 0.00e+00 781.00
IUUC-Dno-029942 Dasypus novemcinctus 96.35 0.00e+00 926.00
IUUC-Dor-030134 Dipodomys ordii 84.98 3.00e-151 528.00
IUUC-Dme-031853 Drosophila melanogaster 55.49 4.00e-149 521.00
IUUC-Ete-032355 Echinops telfairi 88.46 0.00e+00 830.00
IUUC-Eca-033440 Equus caballus 97.97 0.00e+00 933.00
IUUC-Eeu-035230 Erinaceus europaeus 89.36 4.00e-115 407.00
IUUC-Fca-036308 Felis catus 91.68 0.00e+00 860.00
IUUC-Fal-036974 Ficedula albicollis 92.68 0.00e+00 873.00
IUUC-Gmo-038642 Gadus morhua 81.31 0.00e+00 785.00
IUUC-Gga-041019 Gallus gallus 92.68 0.00e+00 873.00
IUUC-Gac-042014 Gasterosteus aculeatus 80.28 0.00e+00 805.00
IUUC-Ggo-045329 Gorilla gorilla 96.75 0.00e+00 932.00
IUUC-Hsa-046712 Homo sapiens 97.16 0.00e+00 932.00
IUUC-Itr-048370 Ictidomys tridecemlineatus 98.32 0.00e+00 840.00
IUUC-Lch-049584 Latimeria chalumnae 86.21 0.00e+00 827.00
IUUC-Loc-051826 Lepisosteus oculatus 80.71 1.00e-167 582.00
IUUC-Laf-054567 Loxodonta africana 96.54 0.00e+00 927.00
IUUC-Mcc-054919 Macaca mulatta 96.35 0.00e+00 931.00
IUUC-Meu-056332 Macropus eugenii 88.84 0.00e+00 842.00
IUUC-Mga-060132 Meleagris gallopavo 92.91 0.00e+00 878.00
IUUC-Mmr-061599 Microcebus murinus 92.71 0.00e+00 876.00
IUUC-Mdo-062186 Monodelphis domestica 95.83 0.00e+00 799.00
IUUC-Mmu-064271 Mus musculus 98.98 0.00e+00 941.00
IUUC-Mpu-066827 Mustela putorius furo 98.77 0.00e+00 825.00
IUUC-Mlu-067528 Myotis lucifugus 96.75 0.00e+00 887.00
IUUC-Nle-068995 Nomascus leucogenys 96.75 0.00e+00 932.00
IUUC-Opr-070518 Ochotona princeps 95.74 0.00e+00 892.00
IUUC-Ont-071650 Oreochromis niloticus 83.27 0.00e+00 824.00
IUUC-Oan-073676 Ornithorhynchus anatinus 93.38 0.00e+00 752.00
IUUC-Ocu-073761 Oryctolagus cuniculus 97.16 0.00e+00 936.00
IUUC-Obr-076705 Oryza brachyantha 29.82 4.00e-58 219.00
IUUC-Ola-087204 Oryzias latipes 80.16 0.00e+00 799.00
IUUC-Oga-088098 Otolemur garnettii 96.35 0.00e+00 926.00
IUUC-Oar-089205 Ovis aries 97.56 0.00e+00 929.00
IUUC-Ptr-091514 Pan troglodytes 96.75 0.00e+00 932.00
IUUC-Pan-092493 Papio anubis 91.65 0.00e+00 886.00
IUUC-Psi-093024 Pelodiscus sinensis 87.06 6.00e-117 412.00
IUUC-Pfo-097256 Poecilia formosa 82.44 0.00e+00 816.00
IUUC-Pab-098504 Pongo abelii 89.05 0.00e+00 833.00
IUUC-Pop-099547 Populus trichocarpa 30.60 6.00e-55 208.00
IUUC-Pca-100700 Procavia capensis 89.05 0.00e+00 828.00
IUUC-Pva-103105 Pteropus vampyrus 96.95 0.00e+00 917.00
IUUC-Sha-107417 Sarcophilus harrisii 92.70 0.00e+00 862.00
IUUC-Sar-113042 Sorex araneus 95.57 0.00e+00 920.00
IUUC-Ssc-115362 Sus scrofa 97.76 0.00e+00 931.00
IUUC-Tgu-117469 Taeniopygia guttata 92.32 0.00e+00 826.00
IUUC-Tru-117976 Takifugu rubripes 80.78 0.00e+00 820.00
IUUC-Tsy-118876 Tarsius syrichta 84.09 9.00e-94 337.00
IUUC-Tni-119831 Tetraodon nigroviridis 80.59 0.00e+00 796.00
IUUC-Tca-121326 Theobroma cacao 28.90 2.00e-59 223.00
IUUC-Tbe-127386 Tupaia belangeri 88.44 8.00e-158 550.00
IUUC-Ttr-128315 Tursiops truncatus 97.56 0.00e+00 930.00
IUUC-Vpa-130383 Vicugna pacos 90.24 0.00e+00 832.00
IUUC-Xtr-132945 Xenopus tropicalis 90.45 0.00e+00 873.00
Created Date 25-Jun-2017

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