iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	16897085; 21203445

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.40e-07	32.8	119	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cl++f   ++  +vlp C+H+fh dC+ +w         + +CPlCr
   Q: 119  CAVCLSEFeesET-GRVLPnCQHTFHVDCIDMW------FHSHSTCPLCR 161
           ********55333.666778*************......9999******8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Protein Sequence
(Fasta)

MNSNDQDPIP FRPEDNNFSG SKTYAMSGKI MLSAIVILFF VVILMVFLHL YARWYLLRAR 60
RRHLRRRSRN RRATMVFFTA DPSTAATSVV ASRGLDPNVI KSLPVFTFSD ETHKDPIECA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTAAGCAT TTTCCCTTTG AAATTTTCAA ACTAATTAAA TAGTTACCAA AACAAAAAGA 60
AGAAGGGCAG AATAGTCAAA AGAGAAAACT CGCGCGTCAA CGTTGGCGTC GTCTTGCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006952--P:defense response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010200--P:response to chitin

KEGG

ath:AT3G16720

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003085	Amborella trichopoda	37.89	4.00e-29	120.00
IUUC-Aly-005973	Arabidopsis lyrata	91.15	1.00e-131	461.00
IUUC-Bol-015679	Brassica oleracea	69.31	3.00e-87	314.00
IUUC-Bra-017659	Brassica rapa	62.83	3.00e-78	283.00
IUUC-Gma-043514	Glycine max	63.57	3.00e-36	144.00
IUUC-Mtr-057631	Medicago truncatula	45.88	1.00e-39	155.00
IUUC-Mac-065089	Musa acuminata	54.22	9.00e-24	102.00
IUUC-Ppa-095981	Physcomitrella patens	40.36	2.00e-27	115.00
IUUC-Pop-098976	Populus trichocarpa	51.54	5.00e-52	197.00
IUUC-Ppe-101773	Prunus persica	50.36	1.00e-43	169.00
IUUC-Smo-109519	Selaginella moellendorffii	51.49	3.00e-24	102.00
IUUC-Sly-111104	Solanum lycopersicum	51.53	1.00e-55	209.00
IUUC-Stu-112132	Solanum tuberosum	51.15	2.00e-56	211.00
IUUC-Tca-121512	Theobroma cacao	55.40	2.00e-56	211.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence