iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036462

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02191672

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000011563.3	ENSFCAT00000011566.3	ENSFCAP00000010736.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-54	177.6	454	492
UBD/Beta-Prp	2.40e-64	217.4	330	526

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 454  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 492
           9**********999******************9999875 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.... 104
           ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++sp    
   Q: 330  QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPtgpa 418
           56677788888888888888887778888888888888888888888888888888888888888888888888888888777776666 PP
   S: 105  .....sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
                s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +  + +
   Q: 419  tsnpnSNIMLASASFDSTVRLWDVERGVCVH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TGGIFEVCW 504
           5555333567888888888888888888888.8888888888888888888888888888888888888888888877..888888888 PP
   S: 189  dsngkelvsgsldgtvklwdlq 210
           +  g  + + + dg+v + dl+
   Q: 505  NARGDKVGASASDGSVCVLDLR 526
           8888888888888888777765 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV 60
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQQQASA AAAAAAAAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCTCACGTT CCCCCCTTTC CACTGCCAGG TTGGGGACAC CCCACAAGAC CCATGCGTCT 60
CTAAGACCGG AGTGGCGCCG AGCGCTGTTT CACATACCTG CTGGCCTCGA GCGGTCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0016575--P:histone deacetylation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

KEGG

fca:101084773

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	94.69	0.00e+00	998.00
IUUC-Apl-003232	Anas platyrhynchos	96.20	0.00e+00	999.00
IUUC-Aca-005035	Anolis carolinensis	95.83	0.00e+00	1003.00
IUUC-Ago-007869	Ashbya gossypii	27.98	6.00e-33	135.00
IUUC-Bta-013202	Bos taurus	97.35	0.00e+00	1009.00
IUUC-Cja-019281	Callithrix jacchus	91.46	0.00e+00	975.00
IUUC-Cfa-020929	Canis familiaris	98.10	0.00e+00	1011.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.43	3.00e-131	461.00
IUUC-Csa-023943	Chlorocebus sabaeus	92.60	0.00e+00	979.00
IUUC-Cin-025704	Ciona intestinalis	72.22	0.00e+00	793.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	1.00e-30	128.00
IUUC-Dno-028926	Dasypus novemcinctus	96.20	0.00e+00	996.00
IUUC-Dme-031939	Drosophila melanogaster	81.47	8.00e-176	610.00
IUUC-Ete-032822	Echinops telfairi	84.44	0.00e+00	843.00
IUUC-Eca-033897	Equus caballus	97.53	0.00e+00	1011.00
IUUC-Fal-037388	Ficedula albicollis	96.39	0.00e+00	1005.00
IUUC-Gga-040671	Gallus gallus	96.58	0.00e+00	1005.00
IUUC-Gac-041851	Gasterosteus aculeatus	89.37	0.00e+00	934.00
IUUC-Ggo-045373	Gorilla gorilla	94.50	0.00e+00	989.00
IUUC-Hsa-045841	Homo sapiens	93.74	0.00e+00	985.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	99.46	0.00e+00	782.00
IUUC-Lch-050535	Latimeria chalumnae	92.03	0.00e+00	978.00
IUUC-Laf-054071	Loxodonta africana	96.98	0.00e+00	1004.00
IUUC-Mcc-055233	Macaca mulatta	92.50	0.00e+00	963.00
IUUC-Mga-059895	Meleagris gallopavo	96.58	0.00e+00	1005.00
IUUC-Mmr-061286	Microcebus murinus	97.36	0.00e+00	1011.00
IUUC-Mmu-063447	Mus musculus	97.53	0.00e+00	1012.00
IUUC-Nle-069151	Nomascus leucogenys	93.55	0.00e+00	979.00
IUUC-Ont-072252	Oreochromis niloticus	89.18	0.00e+00	954.00
IUUC-Oan-073562	Ornithorhynchus anatinus	97.72	0.00e+00	1014.00
IUUC-Oar-089506	Ovis aries	94.69	0.00e+00	1007.00
IUUC-Ptr-090793	Pan troglodytes	92.41	0.00e+00	949.00
IUUC-Pan-091909	Papio anubis	93.21	0.00e+00	983.00
IUUC-Psi-093358	Pelodiscus sinensis	92.38	0.00e+00	961.00
IUUC-Pfo-097214	Poecilia formosa	87.86	0.00e+00	922.00
IUUC-Pab-098317	Pongo abelii	93.23	0.00e+00	962.00
IUUC-Pop-098989	Populus trichocarpa	57.64	1.00e-128	452.00
IUUC-Rno-105857	Rattus norvegicus	97.53	0.00e+00	1012.00
IUUC-Sha-107326	Sarcophilus harrisii	94.31	0.00e+00	1012.00
IUUC-Ssc-115646	Sus scrofa	97.54	0.00e+00	1014.00
IUUC-Tgu-116898	Taeniopygia guttata	96.39	0.00e+00	1001.00
IUUC-Tru-117862	Takifugu rubripes	89.18	0.00e+00	942.00
IUUC-Tni-119656	Tetraodon nigroviridis	89.75	0.00e+00	942.00
IUUC-Ttr-128826	Tursiops truncatus	96.49	0.00e+00	924.00
IUUC-Uma-129469	Ustilago maydis	43.53	3.00e-58	220.00
IUUC-Vvi-131193	Vitis vinifera	56.89	6.00e-129	454.00
IUUC-Xma-133591	Xiphophorus maculatus	87.67	0.00e+00	921.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence