iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093358

Ensembl Protein ID

ENSPSIP00000010207.1

UniProt Accession

K7FQ97; K7FQ97_PELSI

Genbank Protein ID

ENSPSIP00000010207

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01065954

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000009181.1	ENSPSIT00000010260.1	ENSPSIP00000010207.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-54	178.0	442	480
UBD/Beta-Prp	1.90e-64	217.7	318	514

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g+l++s
   Q: 442  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGTLVHS 480
           9**********999*******************999876 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.... 104
           ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++sp    
   Q: 318  QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPtgpg 406
           56666777777777777777777777777777777777777777777777777777777777777777777777777777777776666 PP
   S: 105  .....sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
                s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +  + +
   Q: 407  tsnpnSNIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRG--TGGIFEVCW 492
           5555333567777777777777777777777.7777777777777777777777777777777777777777777777..777777777 PP
   S: 189  dsngkelvsgsldgtvklwdlq 210
           +  g  + + + dg+v + dl+
   Q: 493  NARGDKVGASASDGSVCVLDLR 514
           7777777777777777777765 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

KVPITLMSSD FISWLPFLLS GFSHSAFTFG IESHISQSNI NGTLVPPAAL ISILQKGLQY 60
VEAEISINED GTVFDGRPIE SLSLIDAVMP DVVQTRQQAF REKLAQQQAS AAAAAGGAGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGTGCCTA TCACATTGAT GAGCTCAGAT TTCATATCAT GGCTTCCTTT CCTGCTTTCA 60
GGTTTCTCCC ATTCGGCCTT TACCTTTGGT ATTGAAAGCC ACATTAGTCA ATCCAACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	60.00	1.00e-54	204.00
IUUC-Aml-001450	Ailuropoda melanoleuca	93.20	0.00e+00	963.00
IUUC-Apl-003232	Anas platyrhynchos	92.54	0.00e+00	959.00
IUUC-Aca-005035	Anolis carolinensis	90.72	0.00e+00	957.00
IUUC-Aly-005622	Arabidopsis lyrata	55.84	2.00e-119	422.00
IUUC-Ath-007137	Arabidopsis thaliana	59.23	2.00e-120	426.00
IUUC-Ago-007869	Ashbya gossypii	27.68	9.00e-33	134.00
IUUC-Bta-013202	Bos taurus	91.44	0.00e+00	957.00
IUUC-Bdi-014315	Brachypodium distachyon	61.19	2.00e-134	472.00
IUUC-Bol-016277	Brassica oleracea	56.06	8.00e-126	443.00
IUUC-Bra-016944	Brassica rapa	56.06	3.00e-125	441.00
IUUC-Cja-019281	Callithrix jacchus	89.38	0.00e+00	934.00
IUUC-Cfa-020929	Canis familiaris	92.18	0.00e+00	959.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.43	1.00e-131	462.00
IUUC-Csa-023943	Chlorocebus sabaeus	89.46	0.00e+00	941.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	1.00e-30	128.00
IUUC-Dno-028926	Dasypus novemcinctus	90.48	0.00e+00	942.00
IUUC-Dme-031939	Drosophila melanogaster	82.02	8.00e-176	610.00
IUUC-Ete-032822	Echinops telfairi	80.92	0.00e+00	806.00
IUUC-Eca-033897	Equus caballus	92.94	0.00e+00	961.00
IUUC-Fca-036462	Felis catus	92.38	0.00e+00	961.00
IUUC-Fal-037388	Ficedula albicollis	91.20	0.00e+00	963.00
IUUC-Gga-040671	Gallus gallus	91.01	0.00e+00	963.00
IUUC-Gac-041851	Gasterosteus aculeatus	89.45	0.00e+00	900.00
IUUC-Ggo-045373	Gorilla gorilla	89.20	0.00e+00	943.00
IUUC-Hsa-045841	Homo sapiens	89.56	0.00e+00	944.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	99.19	0.00e+00	776.00
IUUC-Lch-050535	Latimeria chalumnae	91.05	0.00e+00	940.00
IUUC-Laf-054071	Loxodonta africana	90.74	0.00e+00	955.00
IUUC-Mcc-055233	Macaca mulatta	90.04	0.00e+00	927.00
IUUC-Mga-059895	Meleagris gallopavo	90.84	0.00e+00	962.00
IUUC-Mmr-061286	Microcebus murinus	91.48	0.00e+00	960.00
IUUC-Mmu-063447	Mus musculus	92.00	0.00e+00	958.00
IUUC-Nle-069151	Nomascus leucogenys	88.95	0.00e+00	938.00
IUUC-Ont-072252	Oreochromis niloticus	88.52	0.00e+00	915.00
IUUC-Oan-073562	Ornithorhynchus anatinus	91.81	0.00e+00	964.00
IUUC-Obr-076718	Oryza brachyantha	61.66	9.00e-136	476.00
IUUC-Oar-089506	Ovis aries	93.36	0.00e+00	962.00
IUUC-Ptr-090793	Pan troglodytes	87.79	0.00e+00	902.00
IUUC-Pan-091909	Papio anubis	89.16	0.00e+00	942.00
IUUC-Pma-094105	Petromyzon marinus	57.84	2.00e-89	322.00
IUUC-Ppa-095868	Physcomitrella patens	66.02	3.00e-139	488.00
IUUC-Pab-098317	Pongo abelii	88.78	0.00e+00	920.00
IUUC-Pop-098989	Populus trichocarpa	59.79	6.00e-127	447.00
IUUC-Ppe-101572	Prunus persica	63.97	4.00e-128	451.00
IUUC-Rno-105857	Rattus norvegicus	92.00	0.00e+00	958.00
IUUC-Sha-107326	Sarcophilus harrisii	93.36	0.00e+00	970.00
IUUC-Smo-109301	Selaginella moellendorffii	63.22	2.00e-141	495.00
IUUC-Ssc-115646	Sus scrofa	91.70	0.00e+00	963.00
IUUC-Tgu-116898	Taeniopygia guttata	92.73	0.00e+00	962.00
IUUC-Tru-117862	Takifugu rubripes	88.74	0.00e+00	906.00
IUUC-Tni-119656	Tetraodon nigroviridis	89.71	0.00e+00	907.00
IUUC-Tca-121739	Theobroma cacao	53.73	5.00e-125	441.00
IUUC-Tbe-127665	Tupaia belangeri	73.83	0.00e+00	730.00
IUUC-Ttr-128826	Tursiops truncatus	91.91	0.00e+00	878.00
IUUC-Uma-129469	Ustilago maydis	43.53	4.00e-58	219.00
IUUC-Vvi-131193	Vitis vinifera	56.58	2.00e-129	455.00
IUUC-Xtr-131807	Xenopus tropicalis	85.41	0.00e+00	875.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence