iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ppa-095306

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Defective in cullin neddylation protein

Genbank Nucleotide ID

DS545259

Gene Name

PHYPADRAFT_98951

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S181_58V6	PP1S181_58V6.1	PP1S181_58V6.1
PP1S181_58V6	PP1S181_58V6.2	PP1S181_58V6.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	3.00e-80	269.5	83	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkd 96
           ++++lee++ rYkd ++d+i+++g++ fc+dl+vdp d+++Lv++w+++aat+cefs++ef+ gl+++g+ds++kl+  l +++ elkde+kf++
   Q: 83   DPRQLEEFYLRYKDAYSDMILVDGVSAFCDDLQVDPGDVVMLVISWHMKAATMCEFSKQEFIGGLQSIGVDSLDKLKSILTSMRAELKDEHKFRE 177
           6899******************************************************************************************* PP
   S: 97   iYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           iY+faf++ak+kgqksl+ldta+ +w+Ll+aer ++l++ w++fL+ +++k+iskDtW +lLefs++i++ l nYd+egaWP+liDefveyl
   Q: 178  IYNFAFSWAKEKGQKSLALDTALGMWRLLFAERSWPLVEPWCQFLQAKHNKAISKDTWSQLLEFSRTIDPSLMNYDAEGAWPYLIDEFVEYL 269
           ******************************************************************************************97 PP

Organism

Physcomitrella patens

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MLDAASAVAV TGLELCYCRT SRSSIAATMN KLGRGHRDKV QQFMTIAGAN EKAALTALKA 60
SDWNLEGAFE VFFNQPPPRP LTDPRQLEEF YLRYKDAYSD MILVDGVSAF CDDLQVDPGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACTTATCG ACAGTCCAAA TTTGGAGACT CTTCTGTGCG TTTTCACTTT TTAAACCGCC 60
GTGATTTGAT TGTAAGTGTG ATGCTCGAGC CTCGTACGCT GACGCTGGTC CAGTAATCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

KEGG

ppp:PHYPADRAFT_98951

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001879	Ailuropoda melanoleuca	43.15	3.00e-58	217.00
IUUC-Aca-005269	Anolis carolinensis	42.63	1.00e-57	215.00
IUUC-Aly-006285	Arabidopsis lyrata	62.35	8.00e-88	315.00
IUUC-Ath-007531	Arabidopsis thaliana	70.56	4.00e-105	373.00
IUUC-Acl-008172	Aspergillus clavatus	28.46	3.00e-25	108.00
IUUC-Afl-008569	Aspergillus flavus	29.08	7.00e-30	123.00
IUUC-Afu-009005	Aspergillus fumigatus	29.48	1.00e-20	91.70
IUUC-Ang-009664	Aspergillus niger	30.61	4.00e-28	117.00
IUUC-Aor-009902	Aspergillus oryzae	28.44	9.00e-11	58.50
IUUC-Ate-010414	Aspergillus terreus	26.98	8.00e-28	116.00
IUUC-Ame-011763	Astyanax mexicanus	45.97	2.00e-61	228.00
IUUC-Bgr-011991	Blumeria graminis	32.49	2.00e-19	89.00
IUUC-Bci-013824	Botrytis cinerea	32.27	7.00e-31	126.00
IUUC-Bol-016110	Brassica oleracea	72.47	1.00e-108	384.00
IUUC-Bra-017111	Brassica rapa	72.06	4.00e-109	386.00
IUUC-Cel-018441	Caenorhabditis elegans	32.36	1.00e-38	152.00
IUUC-Cpo-022196	Cavia porcellus	43.55	9.00e-59	219.00
IUUC-Csa-023551	Chlorocebus sabaeus	43.37	6.00e-59	219.00
IUUC-Cho-024373	Choloepus hoffmanni	42.74	1.00e-54	205.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	31.49	2.00e-22	98.20
IUUC-Cme-027199	Cyanidioschyzon merolae	29.92	4.00e-08	51.20
IUUC-Dre-028247	Danio rerio	45.35	5.00e-62	230.00
IUUC-Dno-028974	Dasypus novemcinctus	43.37	6.00e-59	219.00
IUUC-Dse-031365	Dothistroma septosporum	27.71	3.00e-27	114.00
IUUC-Dme-032197	Drosophila melanogaster	41.43	3.00e-56	211.00
IUUC-Ete-032371	Echinops telfairi	43.15	2.00e-58	218.00
IUUC-Eca-033242	Equus caballus	43.15	2.00e-58	217.00
IUUC-Eeu-035317	Erinaceus europaeus	43.55	1.00e-58	218.00
IUUC-Fca-036061	Felis catus	42.31	1.00e-58	219.00
IUUC-Ggr-039959	Gaeumannomyces graminis	27.92	1.00e-16	80.90
IUUC-Gga-040935	Gallus gallus	42.97	2.00e-58	217.00
IUUC-Gac-041937	Gasterosteus aculeatus	45.97	1.00e-61	228.00
IUUC-Gma-043516	Glycine max	73.09	2.00e-114	404.00
IUUC-Hvu-047636	Hordeum vulgare	37.90	5.00e-22	96.70
IUUC-Loc-052509	Lepisosteus oculatus	44.98	1.00e-60	224.00
IUUC-Laf-053972	Loxodonta africana	43.95	3.00e-59	220.00
IUUC-Mcc-054700	Macaca mulatta	42.97	3.00e-59	221.00
IUUC-Meu-056791	Macropus eugenii	38.06	7.00e-43	166.00
IUUC-Mtr-057964	Medicago truncatula	73.17	1.00e-112	398.00
IUUC-Mla-058990	Melampsora laricipopulina	38.84	9.00e-16	77.00
IUUC-Mvi-060312	Microbotryum violaceum	33.33	5.00e-40	157.00
IUUC-Mmr-060851	Microcebus murinus	43.15	3.00e-58	217.00
IUUC-Mdo-063074	Monodelphis domestica	43.31	4.00e-58	219.00
IUUC-Mmu-063954	Mus musculus	43.37	3.00e-59	220.00
IUUC-Mac-065016	Musa acuminata	75.98	1.00e-84	305.00
IUUC-Mlu-067701	Myotis lucifugus	42.74	3.00e-57	214.00
IUUC-Nfi-068610	Neosartorya fischeri	30.06	9.00e-21	92.40
IUUC-Nle-069291	Nomascus leucogenys	43.37	6.00e-59	219.00
IUUC-Opr-070682	Ochotona princeps	40.43	2.00e-42	164.00
IUUC-Oan-073031	Ornithorhynchus anatinus	43.55	2.00e-58	218.00
IUUC-Ocu-074648	Oryctolagus cuniculus	43.15	2.00e-58	217.00
IUUC-Ogu-078285	Oryza glumaepatula	75.20	2.00e-113	400.00
IUUC-Ola-086868	Oryzias latipes	44.35	1.00e-59	221.00
IUUC-Olu-087646	Ostreococcus lucimarinus	41.06	2.00e-52	198.00
IUUC-Oga-088621	Otolemur garnettii	43.15	8.00e-59	219.00
IUUC-Oar-090405	Ovis aries	43.15	2.00e-58	218.00
IUUC-Ptr-090735	Pan troglodytes	43.15	2.00e-58	217.00
IUUC-Pan-092825	Papio anubis	43.37	2.00e-59	221.00
IUUC-Pno-095145	Phaeosphaeria nodorum	28.14	2.00e-21	95.10
IUUC-Pfo-096774	Poecilia formosa	43.85	1.00e-60	225.00
IUUC-Pop-098821	Populus trichocarpa	82.14	2.00e-55	206.00
IUUC-Ppe-102032	Prunus persica	73.39	1.00e-113	401.00
IUUC-Pva-102691	Pteropus vampyrus	43.37	5.00e-59	219.00
IUUC-Rno-105016	Rattus norvegicus	43.37	2.00e-59	221.00
IUUC-Sha-106888	Sarcophilus harrisii	43.15	2.00e-58	217.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	28.40	7.00e-22	96.70
IUUC-Spo-108207	Schizosaccharomyces pombe	34.97	8.00e-26	109.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	33.07	4.00e-31	127.00
IUUC-Smo-108750	Selaginella moellendorffii	75.82	2.00e-107	380.00
IUUC-Sly-111489	Solanum lycopersicum	76.52	4.00e-117	412.00
IUUC-Sar-113509	Sorex araneus	43.60	7.00e-39	153.00
IUUC-Ssc-115547	Sus scrofa	43.37	6.00e-59	219.00
IUUC-Tru-117740	Takifugu rubripes	46.56	9.00e-62	229.00
IUUC-Tsy-119599	Tarsius syrichta	43.15	2.00e-58	218.00
IUUC-Tca-121033	Theobroma cacao	74.30	5.00e-117	412.00
IUUC-Tbe-127429	Tupaia belangeri	40.43	3.00e-42	164.00
IUUC-Ttr-129086	Tursiops truncatus	39.92	4.00e-50	190.00
IUUC-Vpa-130048	Vicugna pacos	37.10	7.00e-45	172.00
IUUC-Vvi-130834	Vitis vinifera	74.60	8.00e-116	408.00
IUUC-Xtr-131888	Xenopus tropicalis	43.95	5.00e-59	219.00
IUUC-Xma-134122	Xiphophorus maculatus	43.15	1.00e-60	225.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence