iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sbi-114082

Ensembl Protein ID

Sb10g008350.1

UniProt Accession

C5Z7F3; C5Z7F3_SORBI

Genbank Protein ID

EER89486.1

Protein Name

Defective in cullin neddylation protein

Genbank Nucleotide ID

CM000769

Gene Name

SORBI_010G095700

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Sb10g008350	Sb10g008350.1	Sb10g008350.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	8.50e-85	284.4	54	240
UBD/Alpha-Helix/UBA	6.50e-07	30.1	10	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdi 97
           ++++le++f+rYk+p+ d+i +eg++++c+dl+vdp+di++Lv++w+++aat+cef+r+ef+ gl+++g+dsiek++ kl++l+ elkd +kf+di
   Q: 54   NTRHLEDIFNRYKEPDGDMIMVEGISQLCNDLQVDPQDIVMLVISWHMKAATMCEFTRQEFIGGLQSIGVDSIEKFRGKLPSLRAELKDDNKFRDI 149
           6799******************************************************************************************** PP
   S: 98   YrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           Y+faf++a++kgqksl l+tai +w+Ll+aer+++ll++w++fL+ +++k+is+DtW++lLef k+i+++lsnYd+egaWP+liDefveyl
   Q: 150  YNFAFTWAREKGQKSLSLETAIGMWQLLFAERNWPLLEHWCQFLQVRHNKAISRDTWAQLLEFVKTIDPQLSNYDDEGAWPYLIDEFVEYL 240
           *****************************************************************************************96 PP

UBD/Alpha-Helix/UBA

   S: 5    dkleqlve.MGFdreealqaLraannnleaAveyLld 40
           dk++q++  +G +++ alqaL a++++le A +++++
   Q: 10   DKVQQFMTiTGASEKVALQALKASDWHLEGAFDFFYS 46
           8********************************9987 PP

Organism

Sorghum bicolor

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MYKLGRGNRD KVQQFMTITG ASEKVALQAL KASDWHLEGA FDFFYSQPQI SAVNTRHLED 60
IFNRYKEPDG DMIMVEGISQ LCNDLQVDPQ DIVMLVISWH MKAATMCEFT RQEFIGGLQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCACGGTGG ATTAGACTCG GGCCGCAGCA TTCCTTGAGC TAGCGAGCGA GAGGGAAAGA 60
GGAGAATAAA AAGGGTGGGG GCGAGGCGGC CGGACAGGAG CCGAGCGCAA GAGCTCAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

KEGG

sbi:SORBI_10g008350

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002697	Amborella trichopoda	77.48	8.00e-52	194.00
IUUC-Aly-006285	Arabidopsis lyrata	65.32	1.00e-93	334.00
IUUC-Ago-007806	Ashbya gossypii	26.02	3.00e-20	91.30
IUUC-Acl-008172	Aspergillus clavatus	29.50	4.00e-29	120.00
IUUC-Afl-008569	Aspergillus flavus	32.82	3.00e-35	140.00
IUUC-Afu-009005	Aspergillus fumigatus	28.96	4.00e-20	90.10
IUUC-Ang-009664	Aspergillus niger	32.28	5.00e-31	127.00
IUUC-Aor-009902	Aspergillus oryzae	28.06	2.00e-11	60.50
IUUC-Ate-010414	Aspergillus terreus	31.27	9.00e-34	135.00
IUUC-Cel-018441	Caenorhabditis elegans	33.45	2.00e-41	161.00
IUUC-Cme-027199	Cyanidioschyzon merolae	31.54	9.00e-10	56.60
IUUC-Dse-031365	Dothistroma septosporum	27.94	2.00e-27	115.00
IUUC-Dme-032197	Drosophila melanogaster	42.26	4.00e-57	213.00
IUUC-Fox-037884	Fusarium oxysporum	32.04	8.00e-18	82.40
IUUC-Gma-043545	Glycine max	75.00	4.00e-117	412.00
IUUC-Lma-053103	Leptosphaeria maculans	30.24	3.00e-28	117.00
IUUC-Meu-056535	Macropus eugenii	44.50	2.00e-46	178.00
IUUC-Mla-058990	Melampsora laricipopulina	28.36	1.00e-18	86.70
IUUC-Mac-065016	Musa acuminata	80.87	7.00e-91	325.00
IUUC-Nfi-068610	Neosartorya fischeri	28.96	4.00e-20	90.10
IUUC-Opr-070682	Ochotona princeps	45.21	9.00e-47	179.00
IUUC-Oba-074993	Oryza barthii	88.80	2.00e-136	476.00
IUUC-Obr-076341	Oryza brachyantha	87.20	1.00e-134	471.00
IUUC-Ogl-077099	Oryza glaberrima	88.80	2.00e-136	476.00
IUUC-Ogu-078285	Oryza glumaepatula	88.00	2.00e-135	473.00
IUUC-Oin-079441	Oryza indica	88.80	1.00e-136	477.00
IUUC-Olo-081037	Oryza longistaminata	88.80	1.00e-136	477.00
IUUC-Ome-081357	Oryza meridionalis	88.80	1.00e-136	477.00
IUUC-Oni-082632	Oryza nivara	88.80	9.00e-137	478.00
IUUC-Opu-083351	Oryza punctata	89.32	1.00e-128	450.00
IUUC-Oru-084306	Oryza rufipogon	88.80	1.00e-136	477.00
IUUC-Osa-085307	Oryza sativa	88.80	1.00e-136	477.00
IUUC-Pma-094196	Petromyzon marinus	39.78	2.00e-43	168.00
IUUC-Pop-098821	Populus trichocarpa	76.52	7.00e-54	201.00
IUUC-Sce-106358	Saccharomyces cerevisiae	25.38	4.00e-20	90.90
IUUC-Spo-108207	Schizosaccharomyces pombe	34.69	3.00e-27	114.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	33.33	1.00e-32	132.00
IUUC-Sit-110613	Setaria italica	97.60	5.00e-148	515.00
IUUC-Sly-111489	Solanum lycopersicum	76.83	4.00e-118	416.00
IUUC-Stu-112517	Solanum tuberosum	62.00	5.00e-98	349.00
IUUC-Tru-118119	Takifugu rubripes	43.90	2.00e-61	228.00
IUUC-Tre-121986	Trichoderma reesei	25.85	2.00e-21	95.50
IUUC-Tme-126878	Tuber melanosporum	34.26	2.00e-37	149.00
IUUC-Tbe-127429	Tupaia belangeri	43.94	4.00e-47	180.00
IUUC-Vda-129929	Verticillium dahliae	34.66	2.00e-21	95.90
IUUC-Zma-135642	Zea mays	97.20	2.00e-147	513.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence