iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120197

UUCD1 version

UUC-TeN-00536

Ensembl Protein ID

ENSTNIP00000012137.1

UniProt Accession

H3CV53; H3CV53_TETNG

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36

Gene Name

eif3i; EIF3I; EIF3S2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000009272.1	ENSTNIT00000012328.1	ENSTNIP00000012137.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-19	68.1	50	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+c+  ++ d + +++Gs D+++++WD  tg++l
   Q: 50   GHTGAVWCVdcDW-DtKNVLTGSADNSCRLWDCETGKQL 87
           8*******74367.4488*****************9986 PP

Organism

Tetraodon nigroviridis

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MKPILLQGHE RSITQIKYNR EGDLLFSVAK DTVANVWYSV NGERLGTYNG HTGAVWCVDC 60
DWDTKNVLTG SADNSCRLWD CETGKQLALL ETNSAVRTCG FDFSGNIIMF STDKQMGYQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCTGTGG CAGCCCCGGC GCCTGAAACA CGAGTGTACA TTTGCTTCTT TCTTAACAGT 60
TGCGCGTTGA CCAAAGTGGG CTGATTTAGC TGAGAAAGAT GGTACGTGGT GTTTATAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0001889--P:liver development
GO:0006446--P:regulation of translational initiation
GO:0002040--P:sprouting angiogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	57.52	2.00e-35	142.00
IUUC-Aml-001321	Ailuropoda melanoleuca	83.95	7.00e-171	592.00
IUUC-Atr-002468	Amborella trichopoda	48.78	4.00e-54	204.00
IUUC-Apl-003841	Anas platyrhynchos	84.26	2.00e-173	601.00
IUUC-Aca-005123	Anolis carolinensis	84.00	3.00e-173	600.00
IUUC-Aly-006532	Arabidopsis lyrata	47.56	4.00e-87	314.00
IUUC-Ath-007094	Arabidopsis thaliana	46.65	2.00e-88	318.00
IUUC-Ago-008000	Ashbya gossypii	43.20	4.00e-82	298.00
IUUC-Acl-008098	Aspergillus clavatus	51.51	3.00e-99	354.00
IUUC-Afl-008494	Aspergillus flavus	51.07	2.00e-99	355.00
IUUC-Afu-009080	Aspergillus fumigatus	51.20	2.00e-99	355.00
IUUC-Ani-009230	Aspergillus nidulans	51.52	3.00e-99	354.00
IUUC-Aor-010114	Aspergillus oryzae	51.07	2.00e-99	355.00
IUUC-Ate-010285	Aspergillus terreus	53.35	4.00e-103	367.00
IUUC-Ame-011534	Astyanax mexicanus	92.35	0.00e+00	643.00
IUUC-Bgr-012121	Blumeria graminis	47.72	5.00e-89	320.00
IUUC-Bta-013143	Bos taurus	84.00	2.00e-171	594.00
IUUC-Bci-013950	Botrytis cinerea	50.76	1.00e-97	349.00
IUUC-Bdi-015019	Brachypodium distachyon	48.17	5.00e-89	320.00
IUUC-Bol-015709	Brassica oleracea	45.15	8.00e-84	304.00
IUUC-Bra-017760	Brassica rapa	45.15	3.00e-84	305.00
IUUC-Cel-018226	Caenorhabditis elegans	43.65	2.00e-82	298.00
IUUC-Cja-019741	Callithrix jacchus	84.00	8.00e-172	595.00
IUUC-Cfa-021204	Canis familiaris	83.64	2.00e-170	591.00
IUUC-Cpo-021661	Cavia porcellus	84.26	2.00e-171	594.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	43.57	7.00e-82	296.00
IUUC-Csa-024038	Chlorocebus sabaeus	84.00	8.00e-172	595.00
IUUC-Cin-025597	Ciona intestinalis	57.93	4.00e-117	413.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	50.30	2.00e-94	338.00
IUUC-Cne-026838	Cryptococcus neoformans	48.62	3.00e-93	334.00
IUUC-Cme-027304	Cyanidioschyzon merolae	45.79	1.00e-83	302.00
IUUC-Dre-028567	Danio rerio	91.69	0.00e+00	643.00
IUUC-Dno-029171	Dasypus novemcinctus	84.26	2.00e-171	595.00
IUUC-Dor-030257	Dipodomys ordii	71.59	2.00e-74	272.00
IUUC-Dse-031191	Dothistroma septosporum	49.24	7.00e-93	333.00
IUUC-Dme-031879	Drosophila melanogaster	60.87	4.00e-120	424.00
IUUC-Ete-032336	Echinops telfairi	79.44	2.00e-105	374.00
IUUC-Eca-033259	Equus caballus	83.95	7.00e-171	592.00
IUUC-Eeu-035153	Erinaceus europaeus	65.10	1.00e-50	192.00
IUUC-Fca-036489	Felis catus	83.95	7.00e-171	592.00
IUUC-Fal-037485	Ficedula albicollis	84.88	2.00e-174	604.00
IUUC-Fox-037860	Fusarium oxysporum	48.93	9.00e-94	336.00
IUUC-Fso-038188	Fusarium solani	49.85	3.00e-93	334.00
IUUC-Gmo-039311	Gadus morhua	92.28	0.00e+00	647.00
IUUC-Ggr-040045	Gaeumannomyces graminis	49.70	3.00e-96	344.00
IUUC-Gga-040645	Gallus gallus	82.28	4.00e-172	596.00
IUUC-Gac-042086	Gasterosteus aculeatus	92.62	0.00e+00	643.00
IUUC-Gma-043246	Glycine max	45.71	3.00e-88	318.00
IUUC-Ggo-045578	Gorilla gorilla	84.00	8.00e-172	595.00
IUUC-Hsa-046734	Homo sapiens	84.00	8.00e-172	595.00
IUUC-Hvu-047553	Hordeum vulgare	46.32	1.00e-88	319.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	84.26	2.00e-171	594.00
IUUC-Kpa-049325	Komagataella pastoris	44.48	6.00e-86	310.00
IUUC-Lch-049620	Latimeria chalumnae	84.56	2.00e-158	551.00
IUUC-Lpe-051338	Leersia perrieri	45.02	5.00e-81	293.00
IUUC-Loc-052094	Lepisosteus oculatus	85.14	1.00e-167	582.00
IUUC-Lma-053047	Leptosphaeria maculans	49.24	3.00e-94	338.00
IUUC-Laf-053801	Loxodonta africana	83.65	2.00e-167	580.00
IUUC-Mcc-055498	Macaca mulatta	73.85	6.00e-142	496.00
IUUC-Meu-056729	Macropus eugenii	77.61	2.00e-155	541.00
IUUC-Mor-057025	Magnaporthe oryzae	50.76	2.00e-95	342.00
IUUC-Mpo-057511	Magnaporthe poae	50.46	1.00e-95	342.00
IUUC-Mtr-058051	Medicago truncatula	45.71	5.00e-88	317.00
IUUC-Mla-059061	Melampsora laricipopulina	46.42	8.00e-85	306.00
IUUC-Mga-059229	Meleagris gallopavo	83.44	4.00e-171	593.00
IUUC-Mvi-060399	Microbotryum violaceum	45.78	6.00e-82	297.00
IUUC-Mmr-060764	Microcebus murinus	84.31	3.00e-172	597.00
IUUC-Mdo-062088	Monodelphis domestica	84.31	8.00e-172	595.00
IUUC-Mmu-064304	Mus musculus	84.31	6.00e-172	596.00
IUUC-Mac-065520	Musa acuminata	47.83	6.00e-90	323.00
IUUC-Mpu-066340	Mustela putorius furo	83.95	7.00e-171	592.00
IUUC-Mlu-067111	Myotis lucifugus	83.95	2.00e-171	593.00
IUUC-Nfi-068478	Neosartorya fischeri	51.20	4.00e-99	354.00
IUUC-Ncr-068820	Neurospora crassa	49.70	2.00e-94	338.00
IUUC-Nle-069903	Nomascus leucogenys	83.95	2.00e-171	594.00
IUUC-Opr-070221	Ochotona princeps	82.15	3.00e-166	577.00
IUUC-Ont-071765	Oreochromis niloticus	95.69	0.00e+00	664.00
IUUC-Oan-073660	Ornithorhynchus anatinus	84.01	8.00e-156	542.00
IUUC-Ocu-074039	Oryctolagus cuniculus	83.95	4.00e-171	593.00
IUUC-Oba-075395	Oryza barthii	39.57	9.00e-71	259.00
IUUC-Obr-076334	Oryza brachyantha	42.94	3.00e-80	291.00
IUUC-Ogl-077751	Oryza glaberrima	45.71	3.00e-87	315.00
IUUC-Ogu-078207	Oryza glumaepatula	45.85	5.00e-87	314.00
IUUC-Oin-079878	Oryza indica	46.01	9.00e-88	316.00
IUUC-Olo-080677	Oryza longistaminata	39.21	3.00e-78	285.00
IUUC-Ome-081228	Oryza meridionalis	34.41	2.00e-34	139.00
IUUC-Oni-082411	Oryza nivara	40.00	1.00e-70	259.00
IUUC-Opu-083136	Oryza punctata	45.71	5.00e-87	313.00
IUUC-Oru-084916	Oryza rufipogon	44.48	1.00e-85	309.00
IUUC-Osa-085454	Oryza sativa	46.01	9.00e-88	316.00
IUUC-Ola-087053	Oryzias latipes	92.92	0.00e+00	645.00
IUUC-Olu-087602	Ostreococcus lucimarinus	46.58	2.00e-88	318.00
IUUC-Oga-088154	Otolemur garnettii	83.64	2.00e-170	590.00
IUUC-Oar-089915	Ovis aries	83.95	1.00e-170	592.00
IUUC-Ptr-091124	Pan troglodytes	65.94	1.00e-124	439.00
IUUC-Pan-092035	Papio anubis	84.00	8.00e-172	595.00
IUUC-Psi-094096	Pelodiscus sinensis	81.11	3.00e-109	387.00
IUUC-Pno-094988	Phaeosphaeria nodorum	45.71	6.00e-83	300.00
IUUC-Ppa-095949	Physcomitrella patens	48.16	4.00e-93	334.00
IUUC-Pfo-096101	Poecilia formosa	94.77	0.00e+00	657.00
IUUC-Pab-097726	Pongo abelii	84.00	8.00e-172	595.00
IUUC-Pop-099617	Populus trichocarpa	47.55	3.00e-91	327.00
IUUC-Pca-101014	Procavia capensis	84.00	1.00e-171	595.00
IUUC-Ppe-101320	Prunus persica	46.63	2.00e-87	315.00
IUUC-Pva-102789	Pteropus vampyrus	75.08	1.00e-145	508.00
IUUC-Pgr-103479	Puccinia graminis	47.04	1.00e-84	306.00
IUUC-Ptt-103981	Puccinia triticina	47.35	4.00e-86	311.00
IUUC-Pte-104278	Pyrenophora teres	49.54	3.00e-93	334.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	49.54	3.00e-93	334.00
IUUC-Rno-105867	Rattus norvegicus	66.67	5.00e-123	433.00
IUUC-Sce-106251	Saccharomyces cerevisiae	44.18	4.00e-83	301.00
IUUC-Sha-107039	Sarcophilus harrisii	84.31	5.00e-172	596.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	50.76	4.00e-96	344.00
IUUC-Spo-108314	Schizosaccharomyces pombe	50.15	2.00e-93	335.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	50.15	9.00e-97	346.00
IUUC-Smo-108728	Selaginella moellendorffii	48.00	7.00e-89	320.00
IUUC-Sit-110801	Setaria italica	45.71	4.00e-86	311.00
IUUC-Sly-111326	Solanum lycopersicum	48.01	3.00e-90	324.00
IUUC-Stu-112458	Solanum tuberosum	47.85	4.00e-90	324.00
IUUC-Sbi-114063	Sorghum bicolor	45.09	3.00e-85	308.00
IUUC-Sre-115096	Sporisorium reilianum	46.87	6.00e-84	303.00
IUUC-Ssc-116080	Sus scrofa	84.00	2.00e-171	594.00
IUUC-Tgu-116988	Taeniopygia guttata	84.88	4.00e-174	603.00
IUUC-Tru-118766	Takifugu rubripes	99.08	0.00e+00	679.00
IUUC-Tca-121316	Theobroma cacao	45.40	1.00e-87	316.00
IUUC-Tre-122097	Trichoderma reesei	50.30	1.00e-94	339.00
IUUC-Tvi-122442	Trichoderma virens	50.30	4.00e-95	340.00
IUUC-Tae-125800	Triticum aestivum	46.32	1.00e-88	319.00
IUUC-Tur-126334	Triticum urartu	40.49	2.00e-69	255.00
IUUC-Tme-127038	Tuber melanosporum	51.83	2.00e-101	362.00
IUUC-Ttr-128659	Tursiops truncatus	78.15	4.00e-147	513.00
IUUC-Uma-129464	Ustilago maydis	46.87	2.00e-83	301.00
IUUC-Vda-129841	Verticillium dahliae	52.29	2.00e-97	348.00
IUUC-Vvi-131076	Vitis vinifera	46.79	5.00e-89	320.00
IUUC-Xtr-132395	Xenopus tropicalis	84.31	5.00e-173	599.00
IUUC-Xma-133383	Xiphophorus maculatus	94.46	0.00e+00	655.00
IUUC-Yli-134586	Yarrowia lipolytica	48.47	4.00e-82	297.00
IUUC-Zma-135904	Zea mays	45.40	8.00e-86	310.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence