iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sre-114984

Ensembl Protein ID

CBQ70489

UniProt Accession

E6ZTD2; E6ZTD2_SPORE

Genbank Protein ID

CBQ70489.1

Protein Name

Probable SCF complex member Cullin 1

Genbank Nucleotide ID

FQ311441

Gene Name

sr12385

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
sr12385	CBQ70489	CBQ70489

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	5.00e-170	565.6	40	696

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 13   esv.kkeyeelytavynlclsk.......................vgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlrkifay 89
           e +   +y+elyt +yn  +s                        vga+lY++l  +   +++qv+      ++e lL++y +eW +++++++ ++++fay
   Q: 40   EGMtYPRYMELYTVAYNHFTSSslassiaalgrsagpfgskgtnlVGAELYNHLTSYFRTHLEQVRTGSDGLSEEPLLRYYATEWDRYTTGANFVHRLFAY 140
           5555678************9999****************************************************************************** PP
   S: 90   ldrtyvkk.....skkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnk.......laiykesFEakfleat 176
           l+r++vk+     +k v++v+ Lal  w+++++++   k rl+++llk ie++R+ge+++++l++ vv slv+L+l++       l +y++ FE++f eat
   Q: 141  LNRHWVKRekdegRKYVYTVYILALVQWKEHMFRYvqQKGRLVQALLKQIEKQRNGEVIEASLVKKVVDSLVSLGLDEadtnrqnLDVYRQEFEKPFIEAT 241
           ********888777778******************434558************************************************************ PP
   S: 177  qefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllaelvallrdkktedlsrmykLlsrvlngleellkele 277
           + +y+aes++f+++n  ++Y+kk+e+rl+eee+r++ yl++st tkL+ +++++l+  h ++l +e+++ll+ ++ +dl r+y Llsr+++gle+l++++e
   Q: 242  EVYYTAESDAFVAQNTATDYMKKAETRLKEEEDRVELYLHASTRTKLVPTCDNVLVRRHSTMLWDEFQQLLDLQQADDLFRIYTLLSRIPEGLEPLRQKFE 342
           ***************************************************************************************************** PP
   S: 278  shikeqgkaalt......aeekek.......................................dpkkyVerllelknklqklvseaFnndakFlkaldkaf 333
           +h+k  g+ a++      +                                            dp  yV  lle +    + v+ aF  +a Fl aldka+
   Q: 343  AHVKRVGLDAVEkvigggD----GgaatngaaasgaaasgaaagaassssaatapasaasdslDPGAYVSALLEAHRSNLNTVNVAFRGEAGFLAALDKAC 439
           ***********96555542....044557999********************************************************************* PP
   S: 334  etfvnknsvlka..akspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaefts 432
           ++fvn+n+ + +  +kspEllA++ D lL+ks+k   e+ le+ l++v++vfkyi++kdvF+k+Y k+LakRL++  sas++aE+++i++Lke+cg+e+t+
   Q: 440  RDFVNRNKATGTstSKSPELLAKHTDALLKKSNKTSAENSLEEALTDVMVVFKYIEDKDVFQKFYSKMLAKRLVNFASASDDAEANMISRLKEACGFEYTA 540
           *******7765567*************************************************************************************** PP
   S: 433  kLerMfqdlkvSedlnrqFk..eekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgky 531
           kL+rMf+d+ +S++ln++Fk  + k++++++ +v+++ lvL++g+Wp ++ t ++s+P+el  t+e+f++ Y+ khsgRkL+W+++l++ e+ka++ ++k 
   Q: 541  KLARMFTDMGLSKELNDNFKetMAKNHDKAELDVDFYALVLANGFWPLQAPTTEFSIPTELLPTYERFQRHYSAKHSGRKLTWLWQLSKNEVKANYLQQKL 641
           ********************444566667778999**************88888*********************************************** PP
   S: 532  elqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepe 588
           ++q stfQ+avLL+fn +++++  +l++at+l+++ ++ +l  L + k  vl++ + 
   Q: 642  QFQTSTFQTAVLLQFNANDSLTRAQLQQATGLNDATIKPVLAMLSKAK--VLQAADD 696
           ********************************************9987..7765544 PP

Organism

Sporisorium reilianum

Protein Sequence
(Fasta)

MSGPNPPAAG SSRLPAVHDA KATWEFLEPG IDLMMTRLKE GMTYPRYMEL YTVAYNHFTS 60
SSLASSIAAL GRSAGPFGSK GTNLVGAELY NHLTSYFRTH LEQVRTGSDG LSEEPLLRYY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGGGC CCAACCCGCC AGCAGCCGGG AGCAGCCGTC TGCCCGCCGT TCACGATGCC 60
AAAGCCACCT GGGAGTTCCT CGAACCCGGC ATCGATCTCA TGATGACCCG CCTCAAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:0003688--F:DNA replication origin binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:1903467--P:negative regulation of mitotic DNA replication initiation
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002277	Ailuropoda melanoleuca	45.97	0.00e+00	657.00
IUUC-Apl-003503	Anas platyrhynchos	44.38	5.00e-147	513.00
IUUC-Aca-005030	Anolis carolinensis	39.23	2.00e-132	464.00
IUUC-Ago-007977	Ashbya gossypii	32.62	4.00e-119	420.00
IUUC-Acl-008190	Aspergillus clavatus	55.02	3.00e-130	457.00
IUUC-Afl-008542	Aspergillus flavus	53.93	7.00e-105	373.00
IUUC-Afu-009007	Aspergillus fumigatus	56.22	3.00e-133	467.00
IUUC-Ani-009290	Aspergillus nidulans	49.88	0.00e+00	756.00
IUUC-Ang-009600	Aspergillus niger	51.67	0.00e+00	714.00
IUUC-Aor-009978	Aspergillus oryzae	55.28	6.00e-123	433.00
IUUC-Ate-010584	Aspergillus terreus	50.00	0.00e+00	744.00
IUUC-Ame-011861	Astyanax mexicanus	45.27	0.00e+00	642.00
IUUC-Bgr-012209	Blumeria graminis	49.81	0.00e+00	700.00
IUUC-Bta-012878	Bos taurus	45.97	0.00e+00	656.00
IUUC-Bci-013941	Botrytis cinerea	48.26	0.00e+00	734.00
IUUC-Cel-018294	Caenorhabditis elegans	38.53	2.00e-156	544.00
IUUC-Cja-018965	Callithrix jacchus	45.02	0.00e+00	639.00
IUUC-Cfa-020671	Canis familiaris	45.97	0.00e+00	656.00
IUUC-Cpo-021762	Cavia porcellus	46.10	0.00e+00	660.00
IUUC-Csa-023873	Chlorocebus sabaeus	46.10	0.00e+00	659.00
IUUC-Cin-025547	Ciona intestinalis	44.03	1.00e-178	617.00
IUUC-Csv-026083	Ciona savignyi	45.61	0.00e+00	648.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	48.46	0.00e+00	718.00
IUUC-Cne-026919	Cryptococcus neoformans	49.81	0.00e+00	749.00
IUUC-Dre-027875	Danio rerio	45.65	0.00e+00	642.00
IUUC-Dno-028931	Dasypus novemcinctus	46.22	0.00e+00	657.00
IUUC-Dor-030846	Dipodomys ordii	48.20	2.00e-137	481.00
IUUC-Dse-031472	Dothistroma septosporum	47.62	0.00e+00	692.00
IUUC-Dme-031793	Drosophila melanogaster	43.60	2.00e-172	597.00
IUUC-Ete-033112	Echinops telfairi	45.82	7.00e-77	280.00
IUUC-Eca-034309	Equus caballus	45.97	0.00e+00	656.00
IUUC-Fca-036330	Felis catus	44.64	0.00e+00	626.00
IUUC-Fal-036899	Ficedula albicollis	44.71	9.00e-154	535.00
IUUC-Fox-037705	Fusarium oxysporum	44.93	0.00e+00	668.00
IUUC-Fso-038367	Fusarium solani	45.79	0.00e+00	687.00
IUUC-Gmo-038708	Gadus morhua	45.13	0.00e+00	633.00
IUUC-Ggr-039917	Gaeumannomyces graminis	48.40	0.00e+00	717.00
IUUC-Gga-041038	Gallus gallus	46.10	0.00e+00	659.00
IUUC-Gac-041820	Gasterosteus aculeatus	45.25	0.00e+00	653.00
IUUC-Ggo-045154	Gorilla gorilla	40.05	9.00e-127	445.00
IUUC-Hsa-046034	Homo sapiens	46.10	0.00e+00	659.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	46.10	0.00e+00	659.00
IUUC-Kpa-049231	Komagataella pastoris	35.61	2.00e-132	464.00
IUUC-Lch-049673	Latimeria chalumnae	45.97	0.00e+00	656.00
IUUC-Loc-052490	Lepisosteus oculatus	45.79	0.00e+00	644.00
IUUC-Lma-053191	Leptosphaeria maculans	49.75	0.00e+00	730.00
IUUC-Laf-054582	Loxodonta africana	46.22	0.00e+00	660.00
IUUC-Mcc-055162	Macaca mulatta	45.48	0.00e+00	643.00
IUUC-Meu-055904	Macropus eugenii	47.55	1.00e-74	272.00
IUUC-Mor-057035	Magnaporthe oryzae	49.14	0.00e+00	699.00
IUUC-Mpo-057555	Magnaporthe poae	48.89	0.00e+00	720.00
IUUC-Mla-059021	Melampsora laricipopulina	56.59	0.00e+00	862.00
IUUC-Mga-060078	Meleagris gallopavo	46.10	0.00e+00	659.00
IUUC-Mvi-060519	Microbotryum violaceum	55.64	0.00e+00	895.00
IUUC-Mmr-061312	Microcebus murinus	46.10	0.00e+00	659.00
IUUC-Mdo-062867	Monodelphis domestica	45.85	0.00e+00	652.00
IUUC-Mmu-063336	Mus musculus	46.10	0.00e+00	659.00
IUUC-Mac-065440	Musa acuminata	30.54	1.00e-93	335.00
IUUC-Mpu-066400	Mustela putorius furo	44.56	3.00e-153	533.00
IUUC-Mlu-067800	Myotis lucifugus	45.84	0.00e+00	657.00
IUUC-Nfi-068384	Neosartorya fischeri	56.22	2.00e-133	468.00
IUUC-Ncr-068965	Neurospora crassa	46.89	0.00e+00	686.00
IUUC-Nle-069729	Nomascus leucogenys	46.10	0.00e+00	659.00
IUUC-Opr-071197	Ochotona princeps	33.43	6.00e-101	360.00
IUUC-Ont-071729	Oreochromis niloticus	45.60	0.00e+00	647.00
IUUC-Oan-073309	Ornithorhynchus anatinus	46.10	0.00e+00	659.00
IUUC-Ocu-074661	Oryctolagus cuniculus	45.70	0.00e+00	649.00
IUUC-Ola-087422	Oryzias latipes	45.71	0.00e+00	653.00
IUUC-Oga-088130	Otolemur garnettii	46.10	0.00e+00	659.00
IUUC-Oar-089510	Ovis aries	44.36	5.00e-174	603.00
IUUC-Ptr-090665	Pan troglodytes	46.10	0.00e+00	659.00
IUUC-Pan-092218	Papio anubis	46.10	0.00e+00	659.00
IUUC-Psi-093175	Pelodiscus sinensis	46.22	0.00e+00	660.00
IUUC-Pma-094502	Petromyzon marinus	44.90	0.00e+00	651.00
IUUC-Pno-095067	Phaeosphaeria nodorum	49.94	0.00e+00	762.00
IUUC-Pfo-096705	Poecilia formosa	45.70	0.00e+00	662.00
IUUC-Pab-097578	Pongo abelii	46.10	0.00e+00	659.00
IUUC-Pop-100087	Populus trichocarpa	30.32	3.00e-89	321.00
IUUC-Pca-100242	Procavia capensis	46.49	2.00e-134	471.00
IUUC-Pva-102155	Pteropus vampyrus	40.32	3.00e-152	530.00
IUUC-Pgr-103297	Puccinia graminis	54.58	0.00e+00	873.00
IUUC-Ptt-103706	Puccinia triticina	49.09	1.00e-120	426.00
IUUC-Pte-104257	Pyrenophora teres	49.76	0.00e+00	763.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	49.64	0.00e+00	761.00
IUUC-Rno-105939	Rattus norvegicus	46.10	0.00e+00	659.00
IUUC-Sce-106293	Saccharomyces cerevisiae	31.06	6.00e-120	423.00
IUUC-Sha-106949	Sarcophilus harrisii	46.10	0.00e+00	659.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	43.12	3.00e-165	573.00
IUUC-Spo-108280	Schizosaccharomyces pombe	42.59	2.00e-176	610.00
IUUC-Sar-113138	Sorex araneus	35.75	2.00e-118	418.00
IUUC-Ssc-115829	Sus scrofa	45.79	0.00e+00	644.00
IUUC-Tgu-116950	Taeniopygia guttata	46.10	0.00e+00	659.00
IUUC-Tru-118558	Takifugu rubripes	45.48	0.00e+00	653.00
IUUC-Tsy-119621	Tarsius syrichta	43.34	3.00e-91	327.00
IUUC-Tni-120460	Tetraodon nigroviridis	45.48	0.00e+00	657.00
IUUC-Tre-122223	Trichoderma reesei	46.13	0.00e+00	661.00
IUUC-Tvi-122539	Trichoderma virens	43.02	1.00e-177	615.00
IUUC-Tme-126926	Tuber melanosporum	50.12	0.00e+00	759.00
IUUC-Tbe-127369	Tupaia belangeri	53.31	7.00e-95	340.00
IUUC-Ttr-129022	Tursiops truncatus	45.00	2.00e-143	501.00
IUUC-Uma-129341	Ustilago maydis	85.95	0.00e+00	1251.00
IUUC-Vda-129857	Verticillium dahliae	49.08	0.00e+00	691.00
IUUC-Vpa-130166	Vicugna pacos	41.24	2.00e-133	467.00
IUUC-Xtr-131818	Xenopus tropicalis	45.85	0.00e+00	653.00
IUUC-Xma-134206	Xiphophorus maculatus	45.38	0.00e+00	649.00
IUUC-Yli-134486	Yarrowia lipolytica	38.39	3.00e-155	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence