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Tag Content
UUCD2 ID IUUC-Dre-027762
UUCD1 version UUC-DaR-00126
Ensembl Protein ID ENSDARP00000061069.6
UniProt Accession Q4VBT5; Q1L8F6; Q9DFG7; MKRN1_DANRE
Genbank Protein ID CAK05024.2; CAK05024.2; AAH95243.1; AAG27598.1
Protein Name Probable E3 ubiquitin-protein ligase makorin-1; RING-type E3 ubiquitin transferase makorin-1
Genbank Nucleotide ID CR792454; CT826375; BC095243; AF277173
Gene Name mkrn1; si:ch211-9f20.3; zgc:110403
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000041665.8 ENSDART00000061070.7 ENSDARP00000061069.6
ENSDARG00000041665.8 ENSDART00000142767.1 ENSDARP00000125195.1
ENSDARG00000041665.8 ENSDART00000150786.1 ENSDARP00000125386.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 67.91 5.00e-144 508.00 IUUC-Hsa-046589
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Danio rerio
Functional Description
(View)

Functional Description


     E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
 E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
Protein Sequence
(Fasta)
MAEAAAASTA APAVIGGWTK HVTCRYFMHG LCKEGENCRY SHDLSSCKQT MICKFFQKGC 60
CAFGDRCRYE HTKPSKQDEV PSSKPSMPLT AAPLAGTPEP VSDGPGGTTG AQEKPQGSGA 120
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Protein Fasta Sequence


>IUUC-Dre-027762|E3,RING|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCTAAGGCTT CAACATAAAC AGCAATGGCG GAGGCAGCGG CAGCGTCAAC AGCGGCTCCA 60
GCAGTTATCG GAGGCTGGAC GAAGCACGTA ACCTGCAGGT TAGTGGAAAT CCGCCGATAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-027762|E3,RING|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR026290--Makorin-1
IPR031644--MKRN1_C
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF15815--MKRN1_C
SMART

SM00184--RING
SM00356--ZnF_C3H1
Gene Ontology

GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
KEGG dre:170782
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000297 Aegilops tauschii 45.11 4.00e-41 162.00
IUUC-Aml-001937 Ailuropoda melanoleuca 68.56 2.00e-138 485.00
IUUC-Atr-003024 Amborella trichopoda 36.76 2.00e-63 236.00
IUUC-Apl-004110 Anas platyrhynchos 65.65 7.00e-138 483.00
IUUC-Aca-005385 Anolis carolinensis 68.64 3.00e-154 538.00
IUUC-Aly-006124 Arabidopsis lyrata 34.44 7.00e-53 201.00
IUUC-Ath-006918 Arabidopsis thaliana 41.36 1.00e-40 160.00
IUUC-Ame-011246 Astyanax mexicanus 87.38 1.00e-173 602.00
IUUC-Bta-012318 Bos taurus 67.45 8.00e-151 526.00
IUUC-Bdi-015008 Brachypodium distachyon 36.42 7.00e-55 207.00
IUUC-Bol-016086 Brassica oleracea 33.43 5.00e-49 188.00
IUUC-Bra-018102 Brassica rapa 31.75 3.00e-44 172.00
IUUC-Cel-018642 Caenorhabditis elegans 36.08 5.00e-58 218.00
IUUC-Cja-019550 Callithrix jacchus 67.11 5.00e-132 464.00
IUUC-Cfa-020166 Canis familiaris 67.67 3.00e-145 508.00
IUUC-Cpo-021887 Cavia porcellus 67.37 3.00e-154 538.00
IUUC-Cre-022707 Chlamydomonas reinhardtii 37.73 8.00e-35 140.00
IUUC-Csa-023930 Chlorocebus sabaeus 67.38 6.00e-153 533.00
IUUC-Cho-024307 Choloepus hoffmanni 68.14 1.00e-149 523.00
IUUC-Cin-025619 Ciona intestinalis 46.22 2.00e-97 349.00
IUUC-Csv-026322 Ciona savignyi 43.36 3.00e-86 311.00
IUUC-Dno-029666 Dasypus novemcinctus 66.90 4.00e-147 514.00
IUUC-Dor-030133 Dipodomys ordii 77.09 6.00e-83 301.00
IUUC-Dme-031705 Drosophila melanogaster 36.53 5.00e-63 234.00
IUUC-Ete-032356 Echinops telfairi 60.82 3.00e-84 305.00
IUUC-Eca-033340 Equus caballus 68.09 1.00e-147 516.00
IUUC-Eeu-035167 Erinaceus europaeus 74.06 3.00e-121 428.00
IUUC-Fca-035536 Felis catus 68.09 9.00e-148 516.00
IUUC-Fal-036881 Ficedula albicollis 68.70 8.00e-152 530.00
IUUC-Gmo-039495 Gadus morhua 83.85 5.00e-117 414.00
IUUC-Ggr-039835 Gaeumannomyces graminis 44.64 3.00e-10 60.50
IUUC-Gga-041148 Gallus gallus 68.51 1.00e-145 509.00
IUUC-Gac-041790 Gasterosteus aculeatus 77.48 1.00e-168 585.00
IUUC-Ggo-045245 Gorilla gorilla 67.67 6.00e-161 560.00
IUUC-Hsa-046589 Homo sapiens 67.91 3.00e-157 548.00
IUUC-Hvu-047044 Hordeum vulgare 36.42 4.00e-49 188.00
IUUC-Itr-048468 Ictidomys tridecemlineatus 66.43 2.00e-87 315.00
IUUC-Lch-049777 Latimeria chalumnae 70.75 8.00e-143 499.00
IUUC-Loc-052281 Lepisosteus oculatus 81.65 0.00e+00 684.00
IUUC-Laf-054551 Loxodonta africana 68.60 3.00e-144 504.00
IUUC-Mcc-055160 Macaca mulatta 67.21 4.00e-146 511.00
IUUC-Meu-056809 Macropus eugenii 68.46 6.00e-154 537.00
IUUC-Mpo-057371 Magnaporthe poae 33.87 5.00e-03 36.20
IUUC-Mla-059005 Melampsora laricipopulina 26.67 6.00e-20 92.80
IUUC-Mga-059767 Meleagris gallopavo 66.51 9.00e-141 493.00
IUUC-Mmr-061574 Microcebus murinus 67.44 3.00e-147 515.00
IUUC-Mdo-061974 Monodelphis domestica 69.49 9.00e-157 546.00
IUUC-Mmu-063887 Mus musculus 68.14 1.00e-153 536.00
IUUC-Mac-064993 Musa acuminata 35.50 4.00e-60 224.00
IUUC-Mpu-066756 Mustela putorius furo 67.54 4.00e-134 471.00
IUUC-Mlu-067691 Myotis lucifugus 65.09 6.00e-141 493.00
IUUC-Nle-069845 Nomascus leucogenys 68.14 1.00e-157 549.00
IUUC-Opr-070262 Ochotona princeps 65.20 9.00e-146 510.00
IUUC-Ont-071561 Oreochromis niloticus 79.25 0.00e+00 664.00
IUUC-Oan-073517 Ornithorhynchus anatinus 41.30 4.00e-48 184.00
IUUC-Ocu-074869 Oryctolagus cuniculus 60.81 4.00e-126 444.00
IUUC-Ola-086506 Oryzias latipes 76.87 3.00e-179 621.00
IUUC-Olu-087870 Ostreococcus lucimarinus 44.20 3.00e-30 124.00
IUUC-Oga-088871 Otolemur garnettii 67.67 5.00e-157 547.00
IUUC-Oar-090436 Ovis aries 66.82 2.00e-141 496.00
IUUC-Ptr-091519 Pan troglodytes 67.67 7.00e-157 546.00
IUUC-Pan-092582 Papio anubis 67.51 4.00e-151 528.00
IUUC-Psi-093168 Pelodiscus sinensis 70.59 6.00e-157 546.00
IUUC-Pfo-096075 Poecilia formosa 78.74 0.00e+00 654.00
IUUC-Pab-098764 Pongo abelii 67.38 9.00e-153 533.00
IUUC-Pop-099909 Populus trichocarpa 34.97 3.00e-60 225.00
IUUC-Pca-100903 Procavia capensis 66.59 2.00e-155 541.00
IUUC-Ppe-101248 Prunus persica 43.32 4.00e-42 165.00
IUUC-Pva-103124 Pteropus vampyrus 66.89 1.00e-114 406.00
IUUC-Rno-104976 Rattus norvegicus 67.67 6.00e-154 537.00
IUUC-Sha-107572 Sarcophilus harrisii 68.48 9.00e-149 520.00
IUUC-Smo-109483 Selaginella moellendorffii 33.73 6.00e-54 204.00
IUUC-Sit-110077 Setaria italica 33.72 9.00e-57 214.00
IUUC-Sar-113068 Sorex araneus 67.38 1.00e-142 499.00
IUUC-Sbi-114884 Sorghum bicolor 34.50 2.00e-58 219.00
IUUC-Ssc-115272 Sus scrofa 67.21 5.00e-147 514.00
IUUC-Tgu-116537 Taeniopygia guttata 69.10 5.00e-154 537.00
IUUC-Tru-118205 Takifugu rubripes 74.83 2.00e-175 608.00
IUUC-Tsy-118929 Tarsius syrichta 75.75 2.00e-115 409.00
IUUC-Tni-120744 Tetraodon nigroviridis 73.66 9.00e-161 560.00
IUUC-Tca-121675 Theobroma cacao 34.96 1.00e-54 207.00
IUUC-Tur-126806 Triticum urartu 36.72 2.00e-47 183.00
IUUC-Tme-127048 Tuber melanosporum 27.59 8.00e-17 81.30
IUUC-Tbe-128131 Tupaia belangeri 67.60 2.00e-111 395.00
IUUC-Ttr-129099 Tursiops truncatus 68.06 2.00e-152 532.00
IUUC-Vpa-130663 Vicugna pacos 62.27 9.00e-108 383.00
IUUC-Xtr-132036 Xenopus tropicalis 55.56 7.00e-99 353.00
IUUC-Xma-134162 Xiphophorus maculatus 79.11 0.00e+00 651.00
Created Date 25-Jun-2017

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