iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007873

Ensembl Protein ID

AAS53804

UniProt Accession

Q752Y8; Q752Y8_ASHGO

Genbank Protein ID

AAS53804.1

Protein Name

AFR433Cp

Genbank Nucleotide ID

AE016819

Gene Name

AGOS_AFR433C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AFR433C	AAS53804	AAS53804

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.30e-182	603.8	408	892

Active Site

Position(s)	Description	Evidence
591	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdv..nveahe 94
           YD Qi+++G + q++l + k++lvG g++GcE+lKn +l+Gv     g+i v+D+d +e+snlnrqFLfr++dvg++K+evaa+a  e+npd   +++a  
   Q: 408  YDNQIAVFGLDFQRALANLKIFLVGSGAIGCEMLKNWALMGVgsgpeGKIMVTDNDSIEKSNLNRQFLFRPKDVGRNKSEVAAAATIEMNPDLagHIDAKC 508
           9*******************************************************************************************944567788 PP
   S: 95   esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           +++ +++e+i+   F + +d+V +aldn++ar++v+r+c+ +r+pl+esgtlG++G+++v+i+ lte+ys+s+dpp+k+iP+ctl+++pn+++hti wa  
   Q: 509  DKVGPETEHIFdsdFWNSLDIVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVVIPNLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAks 609
           9********99*****************************************************************************************8 PP
   S: 191  ..........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv....... 274
                     + +n +l + ++ e++l+  +s++++ +++++ ++l s ++ n+e++i++a+ +f+k ++ +i+qll +f++d  t+ ++pfw+       
   Q: 610  lfhgyftetpENVNTYLTQPNFVEQTLK--QSSDIRGILEPIVASL-SDRPYNYEDCIKWARLEFEKKYNDDIQQLLYNFPKDAKTSTGAPFWSgpkrape 707
           8888888888888888877777666666..4577777777775554.468*************************************************** PP
   S: 275  ..................................................sfcsnaealqvpekvekdeevvkasap..........lylllralerfekk 315
                                                             +f +         + +k ++++++++p          +  l  +l + ++ 
   Q: 708  plifdinnpshfqfivagsslraycyglkgddghfdvefykkvlsnvevpEFTP--------RSDVKIQANDDEPDPnanakfeddvMDQLASSLPEPATL 800
           *************************************97776555555553322........3333333333333334444455568899*********** PP
   S: 316  kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
            g ++   +fekddd   +++++taa+n ra +++iep +d +++k iag+iipaiatt+  v Gl+++E++Kvv++  + e++kn f+++a+
   Q: 801  AGFSMVPAEFEKDDDTnhHIEFITAASNCRAMNYNIEP-ADHQKTKFIAGRIIPAIATTTGLVTGLVNLELYKVVDHkmDIEKYKNGFVNLAL 892
           ***************999********************.**************************************556677*****99875 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MSKSDDIDES LYSRQLYVLG KEAMLKMQVS NVLVVGVTGL GVEIAKNVAL AGVRSLTLYD 60
PEAVTVQDLA TQFFLRESDV GQRRDHVTAP RLAELNSYVP VRVAESLEEA RLGEFQVIVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAAGA GTGATGATAT CGACGAGAGC TTGTACTCGC GGCAGCTATA TGTGTTGGGG 60
AAGGAGGCGA TGTTGAAGAT GCAGGTGTCG AATGTGCTTG TTGTGGGCGT GACGGGGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

KEGG

ago:AGOS_AFR433C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	45.34	0.00e+00	809.00
IUUC-Aml-001311	Ailuropoda melanoleuca	54.13	0.00e+00	1078.00
IUUC-Atr-002684	Amborella trichopoda	45.79	0.00e+00	870.00
IUUC-Apl-004158	Anas platyrhynchos	42.23	0.00e+00	698.00
IUUC-Aca-004620	Anolis carolinensis	53.40	0.00e+00	1082.00
IUUC-Aly-005515	Arabidopsis lyrata	45.67	0.00e+00	880.00
IUUC-Ath-006891	Arabidopsis thaliana	45.62	0.00e+00	879.00
IUUC-Acl-008181	Aspergillus clavatus	60.12	0.00e+00	1211.00
IUUC-Afl-008455	Aspergillus flavus	60.33	0.00e+00	1173.00
IUUC-Afu-009065	Aspergillus fumigatus	60.88	0.00e+00	1237.00
IUUC-Ani-009371	Aspergillus nidulans	61.15	0.00e+00	1187.00
IUUC-Ang-009737	Aspergillus niger	59.36	0.00e+00	1187.00
IUUC-Aor-010007	Aspergillus oryzae	60.33	0.00e+00	1172.00
IUUC-Ate-010466	Aspergillus terreus	59.79	0.00e+00	1234.00
IUUC-Ame-010933	Astyanax mexicanus	53.60	0.00e+00	1008.00
IUUC-Bgr-012281	Blumeria graminis	58.32	0.00e+00	1176.00
IUUC-Bta-012767	Bos taurus	54.38	0.00e+00	1096.00
IUUC-Bci-013721	Botrytis cinerea	61.15	0.00e+00	1164.00
IUUC-Bdi-014009	Brachypodium distachyon	45.49	0.00e+00	848.00
IUUC-Bol-015665	Brassica oleracea	45.43	0.00e+00	860.00
IUUC-Bra-017252	Brassica rapa	45.37	0.00e+00	874.00
IUUC-Cel-018260	Caenorhabditis elegans	44.15	0.00e+00	781.00
IUUC-Cja-019152	Callithrix jacchus	54.29	0.00e+00	1089.00
IUUC-Cfa-020622	Canis familiaris	53.50	0.00e+00	1040.00
IUUC-Cpo-022526	Cavia porcellus	54.88	0.00e+00	1082.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	45.70	0.00e+00	799.00
IUUC-Csa-023780	Chlorocebus sabaeus	54.38	0.00e+00	1084.00
IUUC-Cho-024682	Choloepus hoffmanni	39.47	6.00e-93	333.00
IUUC-Cin-025790	Ciona intestinalis	50.10	0.00e+00	1027.00
IUUC-Csv-026084	Ciona savignyi	50.00	0.00e+00	1012.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	59.24	0.00e+00	1226.00
IUUC-Cne-026960	Cryptococcus neoformans	56.26	0.00e+00	1102.00
IUUC-Cme-027290	Cyanidioschyzon merolae	41.25	0.00e+00	766.00
IUUC-Dre-028149	Danio rerio	53.79	0.00e+00	1040.00
IUUC-Dno-028884	Dasypus novemcinctus	54.19	0.00e+00	1085.00
IUUC-Dor-030229	Dipodomys ordii	51.82	0.00e+00	1021.00
IUUC-Dse-031524	Dothistroma septosporum	58.98	0.00e+00	1161.00
IUUC-Dme-032045	Drosophila melanogaster	48.77	0.00e+00	972.00
IUUC-Ete-033124	Echinops telfairi	40.97	1.00e-136	478.00
IUUC-Eca-033330	Equus caballus	54.19	0.00e+00	1084.00
IUUC-Eeu-035323	Erinaceus europaeus	42.17	4.00e-153	533.00
IUUC-Fca-036255	Felis catus	54.48	0.00e+00	1083.00
IUUC-Fal-036848	Ficedula albicollis	41.93	0.00e+00	704.00
IUUC-Fox-038007	Fusarium oxysporum	61.58	0.00e+00	666.00
IUUC-Fso-038339	Fusarium solani	59.80	0.00e+00	1156.00
IUUC-Gmo-039338	Gadus morhua	51.33	0.00e+00	995.00
IUUC-Ggr-039823	Gaeumannomyces graminis	59.84	0.00e+00	1231.00
IUUC-Gga-040747	Gallus gallus	42.54	0.00e+00	706.00
IUUC-Gac-041773	Gasterosteus aculeatus	51.53	0.00e+00	995.00
IUUC-Gma-043198	Glycine max	45.53	0.00e+00	855.00
IUUC-Ggo-045336	Gorilla gorilla	54.48	0.00e+00	1072.00
IUUC-Hsa-045982	Homo sapiens	54.48	0.00e+00	1070.00
IUUC-Hvu-047418	Hordeum vulgare	45.61	0.00e+00	843.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	54.78	0.00e+00	1098.00
IUUC-Kpa-049112	Komagataella pastoris	68.58	0.00e+00	1396.00
IUUC-Lch-050371	Latimeria chalumnae	53.69	0.00e+00	1059.00
IUUC-Lpe-051299	Leersia perrieri	46.18	0.00e+00	885.00
IUUC-Loc-052936	Lepisosteus oculatus	53.89	0.00e+00	1050.00
IUUC-Lma-053315	Leptosphaeria maculans	59.08	0.00e+00	1225.00
IUUC-Laf-053948	Loxodonta africana	53.89	0.00e+00	1057.00
IUUC-Mcc-055843	Macaca mulatta	54.19	0.00e+00	1084.00
IUUC-Meu-056258	Macropus eugenii	54.13	0.00e+00	1068.00
IUUC-Mor-057269	Magnaporthe oryzae	60.69	0.00e+00	1219.00
IUUC-Mpo-057435	Magnaporthe poae	59.47	0.00e+00	1194.00
IUUC-Mtr-058572	Medicago truncatula	46.02	0.00e+00	849.00
IUUC-Mla-059176	Melampsora laricipopulina	58.83	0.00e+00	1115.00
IUUC-Mga-059721	Meleagris gallopavo	42.67	0.00e+00	694.00
IUUC-Mvi-060437	Microbotryum violaceum	55.43	0.00e+00	1081.00
IUUC-Mmr-061405	Microcebus murinus	53.30	0.00e+00	1053.00
IUUC-Mdo-062032	Monodelphis domestica	52.44	0.00e+00	1038.00
IUUC-Mmu-063280	Mus musculus	54.38	0.00e+00	1080.00
IUUC-Mac-065505	Musa acuminata	46.89	0.00e+00	877.00
IUUC-Mpu-066409	Mustela putorius furo	54.48	0.00e+00	1093.00
IUUC-Mlu-067217	Myotis lucifugus	54.04	0.00e+00	1060.00
IUUC-Nfi-068407	Neosartorya fischeri	60.59	0.00e+00	1212.00
IUUC-Ncr-068698	Neurospora crassa	61.83	0.00e+00	1240.00
IUUC-Nle-070072	Nomascus leucogenys	52.21	0.00e+00	999.00
IUUC-Opr-070715	Ochotona princeps	35.84	5.00e-162	563.00
IUUC-Ont-071671	Oreochromis niloticus	53.30	0.00e+00	1027.00
IUUC-Oan-073268	Ornithorhynchus anatinus	41.42	0.00e+00	660.00
IUUC-Ocu-074544	Oryctolagus cuniculus	54.19	0.00e+00	1090.00
IUUC-Oba-075934	Oryza barthii	45.98	0.00e+00	880.00
IUUC-Obr-076244	Oryza brachyantha	46.24	0.00e+00	868.00
IUUC-Ogl-077762	Oryza glaberrima	45.98	0.00e+00	879.00
IUUC-Ogu-078305	Oryza glumaepatula	45.98	0.00e+00	880.00
IUUC-Oin-080154	Oryza indica	45.88	0.00e+00	877.00
IUUC-Olo-081089	Oryza longistaminata	46.08	0.00e+00	883.00
IUUC-Ome-081942	Oryza meridionalis	45.26	0.00e+00	849.00
IUUC-Oni-082447	Oryza nivara	46.14	0.00e+00	881.00
IUUC-Opu-083863	Oryza punctata	45.98	0.00e+00	874.00
IUUC-Oru-084469	Oryza rufipogon	45.98	0.00e+00	880.00
IUUC-Osa-085625	Oryza sativa	46.14	0.00e+00	879.00
IUUC-Ola-087002	Oryzias latipes	53.00	0.00e+00	1031.00
IUUC-Olu-087687	Ostreococcus lucimarinus	43.87	0.00e+00	759.00
IUUC-Oga-088594	Otolemur garnettii	54.43	0.00e+00	1067.00
IUUC-Oar-090068	Ovis aries	54.23	0.00e+00	1087.00
IUUC-Ptr-090609	Pan troglodytes	41.46	0.00e+00	701.00
IUUC-Pan-092114	Papio anubis	54.38	0.00e+00	1087.00
IUUC-Psi-093489	Pelodiscus sinensis	42.26	0.00e+00	703.00
IUUC-Pma-094214	Petromyzon marinus	46.55	1.00e-38	150.00
IUUC-Pno-095154	Phaeosphaeria nodorum	58.08	0.00e+00	1213.00
IUUC-Ppa-095227	Physcomitrella patens	45.48	0.00e+00	848.00
IUUC-Pfo-097184	Poecilia formosa	52.12	0.00e+00	1018.00
IUUC-Pab-097861	Pongo abelii	54.29	0.00e+00	1057.00
IUUC-Pop-098934	Populus trichocarpa	46.36	0.00e+00	888.00
IUUC-Pca-100347	Procavia capensis	52.00	0.00e+00	900.00
IUUC-Ppe-101298	Prunus persica	46.06	0.00e+00	848.00
IUUC-Pva-102584	Pteropus vampyrus	54.38	0.00e+00	1112.00
IUUC-Pgr-103336	Puccinia graminis	55.79	0.00e+00	1053.00
IUUC-Ptt-103939	Puccinia triticina	55.76	0.00e+00	1047.00
IUUC-Pte-104200	Pyrenophora teres	59.76	0.00e+00	1244.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	58.65	0.00e+00	1230.00
IUUC-Rno-105462	Rattus norvegicus	54.29	0.00e+00	1078.00
IUUC-Sce-106245	Saccharomyces cerevisiae	73.84	0.00e+00	1568.00
IUUC-Sha-107142	Sarcophilus harrisii	53.94	0.00e+00	1068.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	57.35	0.00e+00	1191.00
IUUC-Spo-108034	Schizosaccharomyces pombe	57.33	0.00e+00	1156.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	61.39	0.00e+00	1194.00
IUUC-Smo-109211	Selaginella moellendorffii	47.02	0.00e+00	850.00
IUUC-Sit-110294	Setaria italica	46.77	0.00e+00	892.00
IUUC-Sly-110914	Solanum lycopersicum	46.27	0.00e+00	896.00
IUUC-Stu-112109	Solanum tuberosum	45.78	0.00e+00	893.00
IUUC-Sar-113737	Sorex araneus	54.23	0.00e+00	1082.00
IUUC-Sbi-114774	Sorghum bicolor	46.00	0.00e+00	879.00
IUUC-Sre-115148	Sporisorium reilianum	56.48	0.00e+00	1098.00
IUUC-Ssc-115777	Sus scrofa	54.29	0.00e+00	1082.00
IUUC-Tgu-116565	Taeniopygia guttata	41.73	0.00e+00	705.00
IUUC-Tru-118742	Takifugu rubripes	52.51	0.00e+00	989.00
IUUC-Tsy-119436	Tarsius syrichta	36.97	7.00e-166	575.00
IUUC-Tni-120401	Tetraodon nigroviridis	52.81	0.00e+00	995.00
IUUC-Tca-121436	Theobroma cacao	45.69	0.00e+00	881.00
IUUC-Tre-122009	Trichoderma reesei	60.20	0.00e+00	1148.00
IUUC-Tvi-122259	Trichoderma virens	60.33	0.00e+00	1149.00
IUUC-Tae-125676	Triticum aestivum	45.11	0.00e+00	860.00
IUUC-Tur-126189	Triticum urartu	45.44	0.00e+00	811.00
IUUC-Tme-127055	Tuber melanosporum	58.29	0.00e+00	1144.00
IUUC-Tbe-127714	Tupaia belangeri	37.18	7.00e-152	529.00
IUUC-Ttr-128331	Tursiops truncatus	53.94	0.00e+00	1075.00
IUUC-Uma-129387	Ustilago maydis	56.65	0.00e+00	1108.00
IUUC-Vda-129977	Verticillium dahliae	59.94	0.00e+00	1136.00
IUUC-Vpa-130716	Vicugna pacos	41.20	0.00e+00	689.00
IUUC-Vvi-130857	Vitis vinifera	45.31	0.00e+00	876.00
IUUC-Xtr-132026	Xenopus tropicalis	44.64	0.00e+00	767.00
IUUC-Xma-133805	Xiphophorus maculatus	52.12	0.00e+00	1004.00
IUUC-Yli-134547	Yarrowia lipolytica	62.73	0.00e+00	1311.00
IUUC-Zma-135052	Zea mays	44.87	0.00e+00	863.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence