iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bgr-012281

Ensembl Protein ID

CCU74641

UniProt Accession

N1J5F4; N1J5F4_BLUG1

Genbank Protein ID

CCU74641.1

Protein Name

Ubiquitin-activating enzyme E1

Genbank Nucleotide ID

CAUH01000475

Gene Name

BGHDH14_bghG000475000001001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BGHDH14_bghG000475000001001	CCU74641	CCU74641

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.40e-183	608.4	419	904

Active Site

Position(s)	Description	Evidence
602	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahe.. 94
           YD+Qi ++G + qek+   + +lvGag++GcE+lKn +++G+      +i v+Dmd +e+snlnrqFLfr  dvg  K+++aa+a+ ++n+d ++ +++  
   Q: 419  YDGQIIVFGKDFQEKIAGISQFLVGAGAIGCEMLKNWAMIGLgtglnAKISVTDMDSIEKSNLNRQFLFRSNDVGSLKSDCAAAAVERMNSDLKGHIVTlr 519
           ******************************************999999*********************************************97766533 PP
   S: 95   esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           +++ +++e+++   F +k+d+V +aldn++arr+v+++c+  ++pl+esgtlG++G+++v+i+ lte+ys+s+dpp++++P+ctl+++pn +ehti wa  
   Q: 520  DRVGADTENVFdenFWRKLDGVTNALDNVDARRYVDQRCVFFQKPLLESGTLGTKGNTQVVIPRLTESYSSSQDPPEQSFPMCTLRSFPNRIEHTIAWArd 620
           89*******99****************************************************************************************** PP
   S: 191  ..........vlfnklleeeageeevle..kldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv..... 274
                     + +n +l + +  e++l    ld+++ e++    ++ l++e++   e++i++a+ +f+k+++n i+qll +f++d +++s++pfw+     
   Q: 621  lfdslfikpaETVNLYLTQPNYLETTLGggGLDKANLEMI----RDFLVEEKPLGVEDCIKWARLQFEKQYNNAIQQLLYNFPKDSISSSGQPFWSgpkra 717
           ***9999998778877776666666665113444444444....4445678999*********************************************** PP
   S: 275  ...................................................sfcsnaealqvpekvekdeevvkasap...lylllralerfekkkgrkpg 321
                                                                ++ a ++q +++  ++ + ++a+++    +  +++l + +   g k +
   Q: 718  pdalkfdprnefhwtfveaathlhafnysintksldantiqrvldnmiipdFSPNSAVKIQADDSEPDPNASNAAPQDineVSEIVKRLPKPKDMAGFKLT 818
           *******************************999999999999999999963333344555555555555555555555569999999999********** PP
   S: 322  elsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
            ++fekddds  ++d++taa+nlrae+++ie  +d++++k iag+iipaiatt+a v Gl+ +E++Kv++g  + e++kn f+++a+
   Q: 819  PVEFEKDDDSnfHIDFITAASNLRAENYKIEL-ADRHKTKFIAGKIIPAIATTTALVTGLVILELYKVIDGktDIEKYKNGFINLAL 904
           ********************************.**************************************666778******9875 PP

Organism

Blumeria graminis

Protein Sequence
(Fasta)

MTDKTETQIQ HDDALLENSE IDESLYSRQL YVLGHEAMKR MGASNVLVVG LKGLGIEIAK 60
NIALAGVKSL SLYDPNPTVI SDLSSQFFLR PEDLGAPRAT ISAPRVAELN AYTPVIIHDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGACA AAACGGAAAC ACAAATTCAG CACGATGACG CCCTTCTGGA AAACAGTGAA 60
ATCGATGAGT CACTATATAG TCGTCAACTA TATGTCCTTG GACACGAAGC TATGAAGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	44.27	0.00e+00	819.00
IUUC-Aml-001311	Ailuropoda melanoleuca	53.63	0.00e+00	1071.00
IUUC-Atr-002684	Amborella trichopoda	43.25	0.00e+00	800.00
IUUC-Apl-004158	Anas platyrhynchos	40.78	0.00e+00	654.00
IUUC-Aca-004620	Anolis carolinensis	54.01	0.00e+00	1053.00
IUUC-Aly-005515	Arabidopsis lyrata	44.75	0.00e+00	842.00
IUUC-Ath-006891	Arabidopsis thaliana	44.85	0.00e+00	840.00
IUUC-Ago-007873	Ashbya gossypii	58.34	0.00e+00	1139.00
IUUC-Acl-008181	Aspergillus clavatus	69.43	0.00e+00	1441.00
IUUC-Afl-008455	Aspergillus flavus	69.46	0.00e+00	1395.00
IUUC-Afu-009065	Aspergillus fumigatus	69.53	0.00e+00	1468.00
IUUC-Ani-009371	Aspergillus nidulans	68.93	0.00e+00	1422.00
IUUC-Ang-009737	Aspergillus niger	69.66	0.00e+00	1441.00
IUUC-Aor-010007	Aspergillus oryzae	69.46	0.00e+00	1395.00
IUUC-Ate-010466	Aspergillus terreus	69.35	0.00e+00	1472.00
IUUC-Ame-010933	Astyanax mexicanus	52.72	0.00e+00	985.00
IUUC-Bta-012767	Bos taurus	53.57	0.00e+00	1071.00
IUUC-Bci-013721	Botrytis cinerea	76.95	0.00e+00	1564.00
IUUC-Bdi-014843	Brachypodium distachyon	44.56	0.00e+00	796.00
IUUC-Bol-015665	Brassica oleracea	44.93	0.00e+00	829.00
IUUC-Bra-017252	Brassica rapa	43.89	0.00e+00	830.00
IUUC-Cel-018260	Caenorhabditis elegans	44.35	0.00e+00	803.00
IUUC-Cja-019152	Callithrix jacchus	53.73	0.00e+00	1069.00
IUUC-Cfa-020622	Canis familiaris	52.94	0.00e+00	1020.00
IUUC-Cpo-022526	Cavia porcellus	54.22	0.00e+00	1062.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	41.86	0.00e+00	735.00
IUUC-Csa-023780	Chlorocebus sabaeus	53.92	0.00e+00	1067.00
IUUC-Cho-024682	Choloepus hoffmanni	39.75	4.00e-90	324.00
IUUC-Cin-025790	Ciona intestinalis	51.29	0.00e+00	1052.00
IUUC-Csv-026084	Ciona savignyi	51.15	0.00e+00	1044.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	71.23	0.00e+00	1531.00
IUUC-Cne-026960	Cryptococcus neoformans	57.52	0.00e+00	1155.00
IUUC-Cme-027290	Cyanidioschyzon merolae	42.58	0.00e+00	775.00
IUUC-Dre-028149	Danio rerio	53.18	0.00e+00	1025.00
IUUC-Dno-028884	Dasypus novemcinctus	53.73	0.00e+00	1071.00
IUUC-Dor-030229	Dipodomys ordii	51.47	0.00e+00	1004.00
IUUC-Dse-031524	Dothistroma septosporum	68.97	0.00e+00	1406.00
IUUC-Dme-032045	Drosophila melanogaster	50.39	0.00e+00	986.00
IUUC-Ete-033124	Echinops telfairi	42.33	3.00e-146	510.00
IUUC-Eca-033330	Equus caballus	53.63	0.00e+00	1067.00
IUUC-Eeu-035323	Erinaceus europaeus	41.13	2.00e-142	498.00
IUUC-Fca-036255	Felis catus	54.02	0.00e+00	1068.00
IUUC-Fal-036848	Ficedula albicollis	41.50	0.00e+00	668.00
IUUC-Fox-038007	Fusarium oxysporum	68.38	0.00e+00	769.00
IUUC-Fso-038339	Fusarium solani	70.67	0.00e+00	1446.00
IUUC-Gmo-039338	Gadus morhua	52.73	0.00e+00	1017.00
IUUC-Ggr-039823	Gaeumannomyces graminis	70.70	0.00e+00	1542.00
IUUC-Gga-040747	Gallus gallus	40.76	0.00e+00	653.00
IUUC-Gac-041773	Gasterosteus aculeatus	51.32	0.00e+00	982.00
IUUC-Gma-043198	Glycine max	44.48	0.00e+00	831.00
IUUC-Ggo-045336	Gorilla gorilla	54.02	0.00e+00	1059.00
IUUC-Hsa-045982	Homo sapiens	54.02	0.00e+00	1060.00
IUUC-Hvu-047418	Hordeum vulgare	45.15	0.00e+00	812.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	54.12	0.00e+00	1073.00
IUUC-Kpa-049112	Komagataella pastoris	57.79	0.00e+00	1110.00
IUUC-Lch-050371	Latimeria chalumnae	54.21	0.00e+00	1052.00
IUUC-Lpe-051520	Leersia perrieri	44.53	0.00e+00	824.00
IUUC-Loc-052936	Lepisosteus oculatus	53.12	0.00e+00	1045.00
IUUC-Lma-053315	Leptosphaeria maculans	68.79	0.00e+00	1474.00
IUUC-Laf-053948	Loxodonta africana	53.43	0.00e+00	1042.00
IUUC-Mcc-055843	Macaca mulatta	53.92	0.00e+00	1071.00
IUUC-Meu-056258	Macropus eugenii	53.33	0.00e+00	1060.00
IUUC-Mor-057269	Magnaporthe oryzae	71.32	0.00e+00	1529.00
IUUC-Mpo-057435	Magnaporthe poae	70.41	0.00e+00	1503.00
IUUC-Mtr-058572	Medicago truncatula	45.15	0.00e+00	824.00
IUUC-Mla-059176	Melampsora laricipopulina	56.43	0.00e+00	1109.00
IUUC-Mga-059721	Meleagris gallopavo	40.96	0.00e+00	641.00
IUUC-Mvi-060437	Microbotryum violaceum	56.27	0.00e+00	1130.00
IUUC-Mmr-061405	Microcebus murinus	52.79	0.00e+00	1029.00
IUUC-Mdo-062032	Monodelphis domestica	51.99	0.00e+00	1019.00
IUUC-Mmu-063280	Mus musculus	53.82	0.00e+00	1063.00
IUUC-Mac-065505	Musa acuminata	43.55	0.00e+00	817.00
IUUC-Mpu-066409	Mustela putorius furo	53.82	0.00e+00	1074.00
IUUC-Mlu-067217	Myotis lucifugus	53.43	0.00e+00	1056.00
IUUC-Nfi-068407	Neosartorya fischeri	69.53	0.00e+00	1446.00
IUUC-Ncr-068698	Neurospora crassa	73.28	0.00e+00	1547.00
IUUC-Nle-070072	Nomascus leucogenys	51.37	0.00e+00	978.00
IUUC-Opr-070715	Ochotona princeps	36.85	5.00e-170	589.00
IUUC-Ont-071671	Oreochromis niloticus	53.71	0.00e+00	1020.00
IUUC-Oan-073268	Ornithorhynchus anatinus	40.39	1.00e-180	624.00
IUUC-Ocu-074544	Oryctolagus cuniculus	53.92	0.00e+00	1075.00
IUUC-Oba-075120	Oryza barthii	44.82	0.00e+00	806.00
IUUC-Obr-076557	Oryza brachyantha	44.81	0.00e+00	796.00
IUUC-Ogl-077887	Oryza glaberrima	44.82	0.00e+00	807.00
IUUC-Ogu-078793	Oryza glumaepatula	44.18	0.00e+00	806.00
IUUC-Oin-079710	Oryza indica	44.09	0.00e+00	806.00
IUUC-Olo-080255	Oryza longistaminata	43.89	0.00e+00	808.00
IUUC-Ome-081942	Oryza meridionalis	44.63	0.00e+00	808.00
IUUC-Oni-082365	Oryza nivara	44.82	0.00e+00	811.00
IUUC-Opu-083977	Oryza punctata	44.23	0.00e+00	813.00
IUUC-Oru-085015	Oryza rufipogon	44.18	0.00e+00	808.00
IUUC-Osa-085949	Oryza sativa	45.02	0.00e+00	814.00
IUUC-Ola-087002	Oryzias latipes	52.98	0.00e+00	1018.00
IUUC-Olu-087687	Ostreococcus lucimarinus	42.02	0.00e+00	729.00
IUUC-Oga-088594	Otolemur garnettii	54.12	0.00e+00	1058.00
IUUC-Oar-090068	Ovis aries	53.48	0.00e+00	1071.00
IUUC-Ptr-090609	Pan troglodytes	41.51	0.00e+00	655.00
IUUC-Pan-092114	Papio anubis	53.92	0.00e+00	1071.00
IUUC-Psi-093489	Pelodiscus sinensis	40.59	0.00e+00	667.00
IUUC-Pma-094214	Petromyzon marinus	48.57	9.00e-39	150.00
IUUC-Pno-095154	Phaeosphaeria nodorum	67.97	0.00e+00	1452.00
IUUC-Ppa-095227	Physcomitrella patens	46.00	0.00e+00	831.00
IUUC-Pfo-097184	Poecilia formosa	52.54	0.00e+00	1011.00
IUUC-Pab-097861	Pongo abelii	54.02	0.00e+00	1050.00
IUUC-Pop-098934	Populus trichocarpa	45.66	0.00e+00	856.00
IUUC-Pca-100347	Procavia capensis	52.50	0.00e+00	901.00
IUUC-Ppe-102012	Prunus persica	44.80	0.00e+00	849.00
IUUC-Pva-102584	Pteropus vampyrus	54.02	0.00e+00	1100.00
IUUC-Pgr-103336	Puccinia graminis	55.99	0.00e+00	1076.00
IUUC-Ptt-103939	Puccinia triticina	56.09	0.00e+00	1073.00
IUUC-Pte-104200	Pyrenophora teres	68.20	0.00e+00	1467.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	66.96	0.00e+00	1452.00
IUUC-Rno-105462	Rattus norvegicus	53.82	0.00e+00	1063.00
IUUC-Sce-106245	Saccharomyces cerevisiae	57.79	0.00e+00	1166.00
IUUC-Sha-107142	Sarcophilus harrisii	52.94	0.00e+00	1055.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	58.57	0.00e+00	1209.00
IUUC-Spo-108034	Schizosaccharomyces pombe	58.05	0.00e+00	1164.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	76.63	0.00e+00	1578.00
IUUC-Smo-109211	Selaginella moellendorffii	45.79	0.00e+00	817.00
IUUC-Sit-110281	Setaria italica	44.60	0.00e+00	829.00
IUUC-Sly-110914	Solanum lycopersicum	44.97	0.00e+00	843.00
IUUC-Stu-112109	Solanum tuberosum	44.67	0.00e+00	843.00
IUUC-Sar-113737	Sorex araneus	53.92	0.00e+00	1070.00
IUUC-Sbi-114520	Sorghum bicolor	44.99	0.00e+00	835.00
IUUC-Sre-115148	Sporisorium reilianum	56.02	0.00e+00	1098.00
IUUC-Ssc-115777	Sus scrofa	53.88	0.00e+00	1077.00
IUUC-Tgu-116565	Taeniopygia guttata	40.99	0.00e+00	663.00
IUUC-Tru-118742	Takifugu rubripes	53.08	0.00e+00	988.00
IUUC-Tsy-119436	Tarsius syrichta	38.29	2.00e-138	484.00
IUUC-Tni-120401	Tetraodon nigroviridis	53.37	0.00e+00	998.00
IUUC-Tca-121672	Theobroma cacao	44.53	0.00e+00	840.00
IUUC-Tre-122009	Trichoderma reesei	70.35	0.00e+00	1434.00
IUUC-Tvi-122259	Trichoderma virens	71.13	0.00e+00	1446.00
IUUC-Tae-125676	Triticum aestivum	43.72	0.00e+00	818.00
IUUC-Tur-126330	Triticum urartu	44.27	0.00e+00	818.00
IUUC-Tme-127055	Tuber melanosporum	62.60	0.00e+00	1244.00
IUUC-Tbe-127587	Tupaia belangeri	42.36	8.00e-153	532.00
IUUC-Ttr-128331	Tursiops truncatus	53.73	0.00e+00	1060.00
IUUC-Uma-129387	Ustilago maydis	56.76	0.00e+00	1103.00
IUUC-Vda-129977	Verticillium dahliae	69.47	0.00e+00	1412.00
IUUC-Vpa-130716	Vicugna pacos	40.60	0.00e+00	636.00
IUUC-Vvi-130857	Vitis vinifera	44.63	0.00e+00	835.00
IUUC-Xtr-132947	Xenopus tropicalis	37.71	1.00e-177	615.00
IUUC-Xma-133805	Xiphophorus maculatus	52.83	0.00e+00	998.00
IUUC-Yli-134547	Yarrowia lipolytica	58.65	0.00e+00	1226.00
IUUC-Zma-135052	Zea mays	44.77	0.00e+00	829.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence