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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031991
Ensembl Protein ID FBpp0072456
UniProt Accession Q9W0P2; Q9W0P2_DROME
Genbank Protein ID AAF47401.1; BAB15801.1
Protein Name DNA repair protein REV1
Genbank Nucleotide ID AE014296; AB049435
Gene Name Rev1; AAF47401; DmelCG12189; DmREV1; DmRev1; dREV1; dRev1; drev1; REV1; rev1; CG12189; Dmel_CG12189
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0035150 FBtr0072557 FBpp0072456
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBM 25.78 2.00e-58 223.00 IUUC-Sce-106236
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
 Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
Protein Sequence
(Fasta)
MTRDEDNGFS EWGGYFEAKK SKLEEQFAAA SDPFRKSDLF QGISIFVNGR TDPSADELKR 60
IMMVHGGTFH HYERSHTTYI IASVLPDVKV RNMNLSKFIS AKWVVDCLEK KKIVDYKPYL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031991|UBD,UBM|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATAATGAACA TAGGTGTGTC AGCTGAGCGG TATTGGTGGA ATTCAATTTT GGCTTTTTCA 60
TGCTTTTAAA CGATTAAAAA TGACCCGCGA TGAGGATAAT GGTTTTAGTG AATGGGTAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031991|UBD,UBM|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC
PROSITE

PS50172--BRCT
PS50173--UMUC
Pfam

PF16589--BRCT_2
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C
SMART

SM00292--BRCT
Gene Ontology

GO:0005634--C:nucleus
GO:0005657--C:replication fork
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0010569--P:regulation of double-strand break repair via homologous recombination
GO:0019985--P:translesion synthesis
KEGG dme:Dmel_CG12189
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000375 Aegilops tauschii 33.15 7.00e-22 98.60
IUUC-Aml-001185 Ailuropoda melanoleuca 41.30 7.00e-111 394.00
IUUC-Atr-002915 Amborella trichopoda 31.79 5.00e-75 275.00
IUUC-Apl-004054 Anas platyrhynchos 42.40 8.00e-104 371.00
IUUC-Aca-004304 Anolis carolinensis 42.64 7.00e-112 398.00
IUUC-Aly-005696 Arabidopsis lyrata 30.74 3.00e-86 312.00
IUUC-Ath-006893 Arabidopsis thaliana 31.98 5.00e-94 338.00
IUUC-Ago-007722 Ashbya gossypii 27.32 5.00e-42 165.00
IUUC-Acl-008347 Aspergillus clavatus 29.02 9.00e-90 324.00
IUUC-Afl-008444 Aspergillus flavus 31.89 5.00e-79 288.00
IUUC-Afu-008837 Aspergillus fumigatus 31.00 1.00e-79 291.00
IUUC-Ani-009188 Aspergillus nidulans 29.85 5.00e-88 318.00
IUUC-Ang-009866 Aspergillus niger 31.56 1.00e-86 314.00
IUUC-Aor-010107 Aspergillus oryzae 31.89 7.00e-79 288.00
IUUC-Ate-010359 Aspergillus terreus 31.48 2.00e-84 306.00
IUUC-Ame-010664 Astyanax mexicanus 40.34 5.00e-112 398.00
IUUC-Bgr-012244 Blumeria graminis 28.24 1.00e-66 247.00
IUUC-Bta-013405 Bos taurus 41.82 2.00e-106 379.00
IUUC-Bci-013849 Botrytis cinerea 28.40 8.00e-74 271.00
IUUC-Bdi-014066 Brachypodium distachyon 32.19 1.00e-93 337.00
IUUC-Bol-015544 Brassica oleracea 31.38 2.00e-92 333.00
IUUC-Bra-017792 Brassica rapa 29.72 2.00e-87 316.00
IUUC-Cel-018148 Caenorhabditis elegans 33.40 3.00e-82 299.00
IUUC-Cja-019742 Callithrix jacchus 38.19 2.00e-73 270.00
IUUC-Cfa-020112 Canis familiaris 41.53 3.00e-113 402.00
IUUC-Cpo-022152 Cavia porcellus 41.46 9.00e-113 400.00
IUUC-Cre-022951 Chlamydomonas reinhardtii 39.56 2.00e-33 137.00
IUUC-Csa-023504 Chlorocebus sabaeus 42.34 1.00e-107 384.00
IUUC-Cho-024780 Choloepus hoffmanni 38.55 8.00e-43 168.00
IUUC-Cin-025276 Ciona intestinalis 35.42 3.00e-114 405.00
IUUC-Csv-026283 Ciona savignyi 35.98 3.00e-103 368.00
IUUC-Cgl-026726 Colletotrichum gloeosporioides 31.15 4.00e-80 292.00
IUUC-Cne-027079 Cryptococcus neoformans 33.72 6.00e-71 262.00
IUUC-Cme-027346 Cyanidioschyzon merolae 26.97 4.00e-61 229.00
IUUC-Dre-028073 Danio rerio 41.47 4.00e-104 372.00
IUUC-Dno-030038 Dasypus novemcinctus 42.02 2.00e-112 399.00
IUUC-Dor-031100 Dipodomys ordii 36.88 7.00e-97 348.00
IUUC-Dse-031310 Dothistroma septosporum 30.79 2.00e-80 293.00
IUUC-Ete-033082 Echinops telfairi 37.06 4.00e-88 319.00
IUUC-Eca-033471 Equus caballus 41.21 3.00e-110 392.00
IUUC-Eeu-034993 Erinaceus europaeus 38.60 1.00e-88 320.00
IUUC-Fca-035367 Felis catus 41.62 2.00e-112 400.00
IUUC-Fal-036973 Ficedula albicollis 41.57 3.00e-99 356.00
IUUC-Fox-037677 Fusarium oxysporum 29.80 4.00e-82 298.00
IUUC-Fso-038252 Fusarium solani 28.28 2.00e-92 333.00
IUUC-Gmo-039669 Gadus morhua 32.66 4.00e-114 405.00
IUUC-Ggr-039988 Gaeumannomyces graminis 30.32 4.00e-78 286.00
IUUC-Gga-040423 Gallus gallus 41.12 1.00e-101 363.00
IUUC-Gac-042134 Gasterosteus aculeatus 42.92 3.00e-109 389.00
IUUC-Gma-042929 Glycine max 35.09 2.00e-82 299.00
IUUC-Ggo-044528 Gorilla gorilla 42.94 2.00e-107 383.00
IUUC-Hsa-046259 Homo sapiens 42.94 4.00e-107 382.00
IUUC-Hvu-047139 Hordeum vulgare 30.99 1.00e-59 223.00
IUUC-Itr-048621 Ictidomys tridecemlineatus 41.62 8.00e-113 401.00
IUUC-Kpa-049169 Komagataella pastoris 27.42 2.00e-72 266.00
IUUC-Lch-050471 Latimeria chalumnae 40.56 2.00e-107 383.00
IUUC-Lpe-050800 Leersia perrieri 30.83 3.00e-76 279.00
IUUC-Loc-052320 Lepisosteus oculatus 29.90 2.00e-56 213.00
IUUC-Lma-053149 Leptosphaeria maculans 30.27 5.00e-82 298.00
IUUC-Laf-053810 Loxodonta africana 41.34 5.00e-103 369.00
IUUC-Mcc-055574 Macaca mulatta 42.94 2.00e-107 383.00
IUUC-Meu-055945 Macropus eugenii 37.50 3.00e-53 203.00
IUUC-Mor-057195 Magnaporthe oryzae 29.17 4.00e-81 296.00
IUUC-Mpo-057488 Magnaporthe poae 29.89 1.00e-74 274.00
IUUC-Mtr-057955 Medicago truncatula 30.09 2.00e-91 330.00
IUUC-Mla-059027 Melampsora laricipopulina 32.72 8.00e-88 317.00
IUUC-Mga-060156 Meleagris gallopavo 41.58 2.00e-101 363.00
IUUC-Mvi-060398 Microbotryum violaceum 35.85 7.00e-85 308.00
IUUC-Mmr-061113 Microcebus murinus 41.70 1.00e-105 377.00
IUUC-Mdo-063001 Monodelphis domestica 41.40 1.00e-105 377.00
IUUC-Mmu-063180 Mus musculus 41.82 5.00e-105 375.00
IUUC-Mac-065551 Musa acuminata 36.30 2.00e-42 166.00
IUUC-Mpu-066525 Mustela putorius furo 41.41 1.00e-111 397.00
IUUC-Mlu-067877 Myotis lucifugus 41.85 4.00e-105 375.00
IUUC-Nfi-068418 Neosartorya fischeri 27.84 3.00e-90 326.00
IUUC-Ncr-068648 Neurospora crassa 31.86 2.00e-80 293.00
IUUC-Nle-069959 Nomascus leucogenys 42.94 3.00e-107 382.00
IUUC-Opr-070522 Ochotona princeps 39.95 8.00e-79 288.00
IUUC-Ont-072293 Oreochromis niloticus 35.78 3.00e-105 376.00
IUUC-Oan-073519 Ornithorhynchus anatinus 41.14 5.00e-112 398.00
IUUC-Ocu-074492 Oryctolagus cuniculus 42.68 9.00e-107 380.00
IUUC-Oba-075567 Oryza barthii 34.78 7.00e-80 291.00
IUUC-Obr-076332 Oryza brachyantha 35.41 3.00e-78 286.00
IUUC-Ogl-077348 Oryza glaberrima 34.78 7.00e-80 291.00
IUUC-Ogu-078779 Oryza glumaepatula 32.14 5.00e-80 292.00
IUUC-Oin-079738 Oryza indica 30.09 2.00e-88 319.00
IUUC-Olo-080701 Oryza longistaminata 29.00 5.00e-88 318.00
IUUC-Ome-081708 Oryza meridionalis 31.12 1.00e-78 288.00
IUUC-Oni-082251 Oryza nivara 34.37 2.00e-77 283.00
IUUC-Opu-083528 Oryza punctata 31.84 3.00e-75 276.00
IUUC-Oru-084293 Oryza rufipogon 31.15 2.00e-75 276.00
IUUC-Osa-085549 Oryza sativa 31.78 1.00e-79 290.00
IUUC-Ola-086793 Oryzias latipes 37.52 1.00e-109 390.00
IUUC-Olu-087786 Ostreococcus lucimarinus 28.98 3.00e-63 235.00
IUUC-Oga-089006 Otolemur garnettii 41.57 4.00e-105 375.00
IUUC-Oar-089597 Ovis aries 42.63 1.00e-114 407.00
IUUC-Ptr-091520 Pan troglodytes 42.94 3.00e-107 382.00
IUUC-Pan-092333 Papio anubis 42.94 1.00e-107 384.00
IUUC-Psi-094004 Pelodiscus sinensis 41.38 4.00e-105 375.00
IUUC-Pma-094128 Petromyzon marinus 38.89 6.00e-60 224.00
IUUC-Pno-094849 Phaeosphaeria nodorum 28.64 1.00e-74 274.00
IUUC-Ppa-095714 Physcomitrella patens 29.75 1.00e-91 330.00
IUUC-Pfo-096569 Poecilia formosa 41.01 4.00e-109 389.00
IUUC-Pab-097960 Pongo abelii 43.15 1.00e-106 380.00
IUUC-Pop-098921 Populus trichocarpa 32.29 7.00e-69 254.00
IUUC-Pca-100509 Procavia capensis 39.64 8.00e-79 288.00
IUUC-Ppe-101730 Prunus persica 29.98 9.00e-94 337.00
IUUC-Pva-102142 Pteropus vampyrus 42.36 4.00e-106 379.00
IUUC-Pgr-103446 Puccinia graminis 35.24 3.00e-59 223.00
IUUC-Ptt-103849 Puccinia triticina 30.76 7.00e-62 232.00
IUUC-Pte-104128 Pyrenophora teres 31.81 2.00e-79 290.00
IUUC-Pyt-104754 Pyrenophora triticirepentis 31.10 5.00e-79 288.00
IUUC-Rno-104871 Rattus norvegicus 41.87 1.00e-110 394.00
IUUC-Sce-106236 Saccharomyces cerevisiae 26.40 1.00e-60 227.00
IUUC-Sha-106962 Sarcophilus harrisii 40.52 1.00e-104 374.00
IUUC-Sja-107691 Schizosaccharomyces japonicus 27.00 6.00e-62 231.00
IUUC-Spo-108170 Schizosaccharomyces pombe 27.78 1.00e-76 281.00
IUUC-Ssl-108668 Sclerotinia sclerotiorum 31.58 5.00e-80 292.00
IUUC-Smo-109554 Selaginella moellendorffii 31.97 6.00e-90 325.00
IUUC-Sit-110479 Setaria italica 34.04 3.00e-59 223.00
IUUC-Sly-111752 Solanum lycopersicum 33.06 5.00e-74 272.00
IUUC-Stu-112284 Solanum tuberosum 25.42 3.00e-25 109.00
IUUC-Sar-113304 Sorex araneus 41.62 3.00e-108 386.00
IUUC-Sbi-114196 Sorghum bicolor 37.54 3.00e-57 216.00
IUUC-Sre-115151 Sporisorium reilianum 30.70 2.00e-69 257.00
IUUC-Ssc-116104 Sus scrofa 41.77 2.00e-105 376.00
IUUC-Tgu-117438 Taeniopygia guttata 41.78 1.00e-100 361.00
IUUC-Tru-118553 Takifugu rubripes 40.23 9.00e-106 377.00
IUUC-Tsy-119056 Tarsius syrichta 42.06 4.00e-106 379.00
IUUC-Tni-119933 Tetraodon nigroviridis 39.88 2.00e-108 386.00
IUUC-Tca-121376 Theobroma cacao 30.25 2.00e-76 280.00
IUUC-Tre-121972 Trichoderma reesei 28.27 1.00e-87 317.00
IUUC-Tvi-122342 Trichoderma virens 28.56 6.00e-85 308.00
IUUC-Tae-123898 Triticum aestivum 30.43 4.00e-80 292.00
IUUC-Tur-126735 Triticum urartu 23.72 9.00e-28 118.00
IUUC-Tme-126999 Tuber melanosporum 30.30 3.00e-69 256.00
IUUC-Tbe-127280 Tupaia belangeri 45.14 1.00e-32 134.00
IUUC-Ttr-129104 Tursiops truncatus 41.80 9.00e-106 377.00
IUUC-Uma-129562 Ustilago maydis 30.83 3.00e-69 256.00
IUUC-Vda-129862 Verticillium dahliae 30.88 6.00e-82 298.00
IUUC-Vpa-130819 Vicugna pacos 43.58 9.00e-65 241.00
IUUC-Vvi-131111 Vitis vinifera 31.78 3.00e-75 276.00
IUUC-Xtr-132629 Xenopus tropicalis 39.10 6.00e-94 338.00
IUUC-Xma-134065 Xiphophorus maculatus 39.85 3.00e-106 379.00
IUUC-Yli-134633 Yarrowia lipolytica 30.82 3.00e-57 216.00
IUUC-Zma-135176 Zea mays 33.97 8.00e-75 274.00
Created Date 25-Jun-2017

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