• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Pma-094484
Ensembl Protein ID ENSPMAP00000008431.1
UniProt Accession S4RT91; S4RT91_PETMA
Protein Name Ubiquitin-related modifier 1
Gene Name urm1; URM1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPMAG00000007668.1 ENSPMAT00000008469.1 ENSPMAP00000008431.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 45.68 6.00e-14 70.10 IUUC-Sce-106366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Petromyzon marinus
Functional Description
(View)

Functional Description


     Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
 Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Protein Sequence
(Fasta)
MAAPISLNVE FGGGAELLFG GVKSHKVELS QQEKPWDVRQ LLVWIRKNLL KERPELFIQG 60
DNVRPGILVL INDTDWELLG ELDYKLVDQD TVVFISTLHG G 101
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pma-094484|ULD,UBQ_Other|Petromyzon marinus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATCCGAGGC GGGGTCCTCG CAGCAGCAAT GGCCGCGCCC ATCTCGCTCA ACGTGGAGTT 60
CGGGTGAGTT CGCGAACGGG TGGTGGTTTG TTGGTATCGC CTGAAATGGT TCGTGATTTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pma-094484|ULD,UBQ_Other|Petromyzon marinus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway
Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1
Pfam

PF09138--Urm1
Gene Ontology

GO:0005829--C:cytosol
GO:0032447--P:protein urmylation
GO:0034227--P:tRNA thio-modification
GO:0002098--P:tRNA wobble uridine modification
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002254 Ailuropoda melanoleuca 79.21 9.00e-45 169.00
IUUC-Atr-003089 Amborella trichopoda 57.58 2.00e-29 118.00
IUUC-Apl-003382 Anas platyrhynchos 75.82 2.00e-37 145.00
IUUC-Aca-004981 Anolis carolinensis 76.24 6.00e-44 166.00
IUUC-Aly-005517 Arabidopsis lyrata 55.43 3.00e-26 107.00
IUUC-Ath-006718 Arabidopsis thaliana 56.63 7.00e-24 100.00
IUUC-Ago-007917 Ashbya gossypii 41.41 5.00e-18 80.90
IUUC-Acl-008054 Aspergillus clavatus 68.00 2.00e-15 71.60
IUUC-Afl-008704 Aspergillus flavus 52.22 2.00e-18 81.60
IUUC-Aor-009890 Aspergillus oryzae 52.94 3.00e-22 95.50
IUUC-Bta-012448 Bos taurus 80.20 5.00e-45 170.00
IUUC-Bci-013865 Botrytis cinerea 44.55 4.00e-20 88.20
IUUC-Bdi-014980 Brachypodium distachyon 68.75 2.00e-23 99.40
IUUC-Bol-016055 Brassica oleracea 55.56 2.00e-22 95.50
IUUC-Bra-016845 Brassica rapa 55.56 2.00e-22 95.50
IUUC-Cel-018485 Caenorhabditis elegans 38.10 3.00e-12 61.60
IUUC-Cja-019587 Callithrix jacchus 81.19 5.00e-45 170.00
IUUC-Cfa-020653 Canis familiaris 79.21 8.00e-45 169.00
IUUC-Cpo-021622 Cavia porcellus 81.19 5.00e-45 170.00
IUUC-Cre-023015 Chlamydomonas reinhardtii 55.10 8.00e-27 109.00
IUUC-Csa-023756 Chlorocebus sabaeus 79.75 7.00e-34 134.00
IUUC-Cgl-026518 Colletotrichum gloeosporioides 44.55 1.00e-19 86.70
IUUC-Cne-026953 Cryptococcus neoformans 51.46 2.00e-25 106.00
IUUC-Cme-027314 Cyanidioschyzon merolae 45.36 5.00e-19 84.00
IUUC-Dre-027884 Danio rerio 75.25 2.00e-42 162.00
IUUC-Dno-029262 Dasypus novemcinctus 80.00 2.00e-34 136.00
IUUC-Dor-030601 Dipodomys ordii 56.44 3.00e-24 101.00
IUUC-Dme-031893 Drosophila melanogaster 60.78 7.00e-31 123.00
IUUC-Ete-032773 Echinops telfairi 78.22 1.00e-41 159.00
IUUC-Eca-034187 Equus caballus 80.20 6.00e-45 170.00
IUUC-Eeu-034808 Erinaceus europaeus 75.25 3.00e-43 164.00
IUUC-Fca-036107 Felis catus 78.22 2.00e-44 168.00
IUUC-Fal-036607 Ficedula albicollis 74.73 6.00e-37 143.00
IUUC-Fox-037698 Fusarium oxysporum 42.31 4.00e-20 88.20
IUUC-Gmo-039492 Gadus morhua 74.26 8.00e-42 159.00
IUUC-Ggr-039965 Gaeumannomyces graminis 41.35 5.00e-17 78.60
IUUC-Gga-041268 Gallus gallus 77.23 2.00e-43 165.00
IUUC-Gac-042111 Gasterosteus aculeatus 77.23 2.00e-44 168.00
IUUC-Gma-043240 Glycine max 56.79 7.00e-23 97.10
IUUC-Ggo-045176 Gorilla gorilla 78.48 1.00e-26 110.00
IUUC-Hsa-046077 Homo sapiens 79.21 7.00e-38 146.00
IUUC-Itr-048111 Ictidomys tridecemlineatus 79.78 9.00e-32 125.00
IUUC-Kpa-049157 Komagataella pastoris 49.49 3.00e-21 91.70
IUUC-Lch-049889 Latimeria chalumnae 78.22 7.00e-45 170.00
IUUC-Lpe-050783 Leersia perrieri 57.83 1.00e-22 95.90
IUUC-Loc-052400 Lepisosteus oculatus 76.24 6.00e-43 163.00
IUUC-Lma-053259 Leptosphaeria maculans 43.56 3.00e-19 85.10
IUUC-Laf-053596 Loxodonta africana 79.61 1.00e-43 166.00
IUUC-Mcc-054845 Macaca mulatta 76.53 4.00e-40 154.00
IUUC-Meu-055968 Macropus eugenii 79.21 7.00e-45 169.00
IUUC-Mor-057126 Magnaporthe oryzae 39.42 4.00e-16 75.10
IUUC-Mpo-057311 Magnaporthe poae 43.56 2.00e-18 83.60
IUUC-Mtr-058266 Medicago truncatula 59.74 8.00e-23 96.70
IUUC-Mla-058847 Melampsora laricipopulina 42.72 3.00e-14 68.60
IUUC-Mga-059468 Meleagris gallopavo 75.82 1.00e-37 145.00
IUUC-Mvi-060235 Microbotryum violaceum 56.41 3.00e-18 82.80
IUUC-Mdo-061948 Monodelphis domestica 79.21 8.00e-45 169.00
IUUC-Mmu-063946 Mus musculus 79.21 1.00e-44 169.00
IUUC-Mac-064812 Musa acuminata 57.83 5.00e-24 100.00
IUUC-Mpu-066763 Mustela putorius furo 79.21 8.00e-44 166.00
IUUC-Mlu-066970 Myotis lucifugus 81.01 5.00e-34 133.00
IUUC-Ncr-068824 Neurospora crassa 44.55 2.00e-18 82.80
IUUC-Nle-069849 Nomascus leucogenys 79.75 6.00e-34 134.00
IUUC-Opr-070227 Ochotona princeps 81.19 5.00e-45 170.00
IUUC-Ont-072530 Oreochromis niloticus 76.24 3.00e-43 164.00
IUUC-Oan-073191 Ornithorhynchus anatinus 72.16 2.00e-37 145.00
IUUC-Ocu-074460 Oryctolagus cuniculus 78.57 1.00e-42 162.00
IUUC-Oba-075499 Oryza barthii 58.54 6.00e-23 98.60
IUUC-Obr-076896 Oryza brachyantha 54.22 1.00e-21 94.40
IUUC-Ogl-077834 Oryza glaberrima 58.54 2.00e-23 99.00
IUUC-Ogu-078622 Oryza glumaepatula 58.54 2.00e-23 99.00
IUUC-Oin-079358 Oryza indica 58.54 5.00e-23 99.00
IUUC-Olo-081035 Oryza longistaminata 56.52 7.00e-24 101.00
IUUC-Oni-082425 Oryza nivara 58.54 2.00e-23 99.00
IUUC-Opu-083461 Oryza punctata 56.79 3.00e-22 96.30
IUUC-Oru-084875 Oryza rufipogon 59.15 2.00e-20 88.60
IUUC-Oga-089128 Otolemur garnettii 81.19 3.00e-45 171.00
IUUC-Oar-089896 Ovis aries 80.20 5.00e-45 170.00
IUUC-Ptr-091618 Pan troglodytes 78.48 1.00e-26 110.00
IUUC-Pan-092238 Papio anubis 79.75 9.00e-34 134.00
IUUC-Psi-093879 Pelodiscus sinensis 78.22 3.00e-43 164.00
IUUC-Ppa-095801 Physcomitrella patens 54.32 2.00e-21 92.40
IUUC-Pfo-097192 Poecilia formosa 75.25 7.00e-44 166.00
IUUC-Pab-098203 Pongo abelii 79.21 4.00e-38 147.00
IUUC-Pop-099614 Populus trichocarpa 56.63 1.00e-23 99.80
IUUC-Pca-100507 Procavia capensis 79.75 8.00e-34 132.00
IUUC-Ppe-101174 Prunus persica 58.59 4.00e-29 117.00
IUUC-Pva-102735 Pteropus vampyrus 80.20 8.00e-42 159.00
IUUC-Pgr-103510 Puccinia graminis 42.72 2.00e-13 65.90
IUUC-Ptt-103918 Puccinia triticina 39.81 3.00e-12 62.00
IUUC-Pte-104173 Pyrenophora teres 43.69 9.00e-20 86.70
IUUC-Pyt-104806 Pyrenophora triticirepentis 43.69 8.00e-20 87.00
IUUC-Rno-105820 Rattus norvegicus 78.22 6.00e-44 167.00
IUUC-Sce-106366 Saccharomyces cerevisiae 44.44 7.00e-19 83.60
IUUC-Sja-107727 Schizosaccharomyces japonicus 42.71 4.00e-16 74.70
IUUC-Spo-108074 Schizosaccharomyces pombe 41.84 6.00e-10 53.90
IUUC-Smo-108944 Selaginella moellendorffii 65.17 1.00e-28 115.00
IUUC-Sit-110277 Setaria italica 58.02 4.00e-23 97.40
IUUC-Sly-111505 Solanum lycopersicum 57.83 1.00e-24 102.00
IUUC-Stu-112076 Solanum tuberosum 56.63 3.00e-24 101.00
IUUC-Sbi-114274 Sorghum bicolor 64.06 1.00e-22 96.70
IUUC-Sre-114953 Sporisorium reilianum 58.82 2.00e-26 108.00
IUUC-Ssc-115418 Sus scrofa 80.20 1.00e-44 169.00
IUUC-Tgu-117311 Taeniopygia guttata 74.73 7.00e-37 143.00
IUUC-Tru-118598 Takifugu rubripes 75.28 2.00e-36 141.00
IUUC-Tni-120109 Tetraodon nigroviridis 72.55 1.00e-39 152.00
IUUC-Tca-120942 Theobroma cacao 55.42 1.00e-22 95.90
IUUC-Tre-122099 Trichoderma reesei 45.74 9.00e-14 66.20
IUUC-Tvi-122285 Trichoderma virens 48.08 2.00e-18 82.80
IUUC-Tae-125193 Triticum aestivum 57.83 3.00e-23 98.20
IUUC-Tur-126677 Triticum urartu 50.53 1.00e-20 90.10
IUUC-Tme-127120 Tuber melanosporum 47.12 8.00e-24 100.00
IUUC-Tbe-128050 Tupaia belangeri 57.43 2.00e-26 108.00
IUUC-Ttr-129019 Tursiops truncatus 77.23 1.00e-41 159.00
IUUC-Uma-129483 Ustilago maydis 54.90 2.00e-23 98.60
IUUC-Vda-129690 Verticillium dahliae 36.61 3.00e-13 65.50
IUUC-Vvi-131174 Vitis vinifera 56.63 6.00e-24 100.00
IUUC-Xma-133862 Xiphophorus maculatus 75.25 7.00e-44 166.00
IUUC-Yli-134398 Yarrowia lipolytica 40.40 3.00e-16 74.70
IUUC-Zma-134964 Zea mays 55.17 2.00e-22 95.90
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved