iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118528

Ensembl Protein ID

ENSTRUP00000002315.1

UniProt Accession

H2RQA0; H2RQA0_TAKRU

Protein Name

Uncharacterized protein

Gene Name

fzr1b; LOC101076451

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000000982.1	ENSTRUT00000002325.1	ENSTRUP00000002315.1
ENSTRUG00000000982.1	ENSTRUT00000002326.1	ENSTRUP00000002316.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	2.00e-143	478.4	173	475
E3 adaptor/Cullin RING/DCX/DWD	1.10e-26	93.0	308	343

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWs+ n l+v+Lg++vylwsa+t++v++l+dl  ++d+vtsv w e+g l+avGt+kg v+i+D++  +k
   Q: 173  PFKVLDAPELQDDFYLNLVDWSAGNLLSVGLGACVYLWSACTSQVTRLCDLsVDGDSVTSVCWNERGGLVAVGTHKGYVQIWDAAGGRK 261
           689************************************************999*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfke 177
           + tl+ghsarvgaL+Wn e+lssGsrd+ il+rd+r++ +  ++lq+h+qevCGlkw+ d+++LasGGnDn++ vw++ss  P++++++
   Q: 262  LTTLEGHSARVGALAWNGEQLSSGSRDRVILQRDIRTPPTAERRLQGHRQEVCGLKWSPDHQHLASGGNDNKLLVWNSSSLLPVQQYSD 350
           ***************************************************************************************** PP
   S: 178  hkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           h aavkaiawsP+q++lLasGGGtaDrc++fwntltg+ l++ dtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+gh
   Q: 351  HLAAVKAIAWSPHQHGLLASGGGTADRCLRFWNTLTGQALQSTDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGH 439
           ***************************************************************************************** PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ++Rvl+la+spdgeaivt+agDetlrfw++f+k++ 
   Q: 440  SYRVLYLAVSPDGEAIVTGAGDETLRFWNVFSKTRC 475
           ********************************9875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH  +v++l++ +d  +l+sG++D+++ vW+ ++  
   Q: 308  GHRQEVCGLKWsPDhQHLASGGNDNKLLVWNSSSLL 343
           8***********999***************976655 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MDQDYERRLL RQINHQNLPA EPRQAKVRDC VSAACSPVSV KSGDRFIPTR AGSNWSINFH 60
YANENCRSPD QSHKAKDASS DSSKDAVAYA ALLRNELLGA GIESVPDPHT DERRHAVLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCAAG ACTACGAGAG ACGGCTGCTG AGGCAGATTA ACCACCAGAA CCTCCCGGCA 60
GAGCCCCGCC AGGCAAAGGT CAGAGATGGA TGACCCCAGA AAAGGGCATT CCTCGCCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011773	Astyanax mexicanus	89.25	0.00e+00	907.00
IUUC-Bol-016301	Brassica oleracea	55.18	8.00e-138	483.00
IUUC-Bra-017453	Brassica rapa	55.18	7.00e-138	483.00
IUUC-Dre-027860	Danio rerio	90.67	0.00e+00	917.00
IUUC-Fox-037814	Fusarium oxysporum	62.20	4.00e-123	434.00
IUUC-Gmo-039431	Gadus morhua	86.61	0.00e+00	876.00
IUUC-Gac-041566	Gasterosteus aculeatus	92.49	0.00e+00	898.00
IUUC-Loc-052240	Lepisosteus oculatus	84.18	0.00e+00	854.00
IUUC-Ont-071725	Oreochromis niloticus	94.32	0.00e+00	956.00
IUUC-Ola-086983	Oryzias latipes	92.53	0.00e+00	937.00
IUUC-Olu-087647	Ostreococcus lucimarinus	52.68	2.00e-99	356.00
IUUC-Ppa-095366	Physcomitrella patens	58.22	3.00e-138	485.00
IUUC-Pfo-096991	Poecilia formosa	91.68	0.00e+00	885.00
IUUC-Tni-120312	Tetraodon nigroviridis	95.75	0.00e+00	911.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence