iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054545

UUCD1 version

UUC-LoA-01118

Ensembl Protein ID

ENSLAFP00000012977.3

UniProt Accession

G3TF89; G3TF89_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP53

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000015483.3	ENSLAFT00000015483.3	ENSLAFP00000012977.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.90e-24	84.8	31	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee...fs 85
           Gl N   +N+C++NS++Q+L+++  +r+ l   + + ++ +      +++ ++l+++f+++++s++ka    ++ +al++  +    f+
   Q: 31   GLLNEpgQNSCFLNSAVQVLWQLDIFRRSLRILTGHVCQGD------ACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDeqrFQ 113
           55555447**********************99777777765......7*************9999999999997777776543322399 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
                Da E+++ +l++++ ++                     +++ +  ++++++ ++ F ++l +q++c +c+ +s    pf+++  
   Q: 114  LGFMDDAAECFENILERIHFHI-------------------VPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPL-PFTEFVR 182
           9999******************...................12235678999***********************999554.7777777 PP
   S: 175  pvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRf..sfseeqksrekinkk 252
            ++    +++             +++++  ++ + +++ +   ++c +k + ++   l ++Pe+ ++ L +   + + ++++ + + ++
   Q: 183  YISTTALCNEVekmmerherFKPEMFAELLQAANTTDDYRKCPSNCGQKIKIRRV--LMNCPEIVTIGLVWDsdHSDLTEDVVRNLATH 269
           7775554433344445555334467788888888888777777888888865444..6688**********933344444555555555 PP
   S: 253  vefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfY 335
           +++p       + +++e  ++++ +  L+++++++      HY+a++ ++k + W+ fdD +V+ev  ++++v++++     ++ +lfY
   Q: 270  LYLPGL----FYRVTDE--NARNSELHLVGIICYTS----QHYCAFAFHTKSSkWVFFDDATVKEVgsRWKDVVSKCIrchFQPLLLFY 348
           555533....2333333..3348999********97....9********77767***********965689999976688889999999 PP
   S: 336  k 336
            
   Q: 349  A 349
           6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAWVKFLRKP GGNLGKVYQP GSMLSLAPTK GLLNEPGQNS CFLNSAVQVL WQLDIFRRSL 60
RILTGHVCQG DACIFCALKT IFAQFQHSRE KALPSDNIRH ALAESFKDEQ RFQLGFMDDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGGG TGAAATTCTT ACGGAAACCT GGTGGCAATC TCGGAAAAGT TTATCAACCT 60
GGGAGCATGC TATCTCTAGC CCCTACCAAA GGCTTATTAA ATGAACCAGG ACAAAACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0001508--P:action potential
GO:0051402--P:neuron apoptotic process
GO:0016579--P:protein deubiquitination
GO:0010996--P:response to auditory stimulus
GO:0007605--P:sensory perception of sound

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002136	Ailuropoda melanoleuca	83.47	0.00e+00	1774.00
IUUC-Atr-002451	Amborella trichopoda	29.97	4.00e-38	154.00
IUUC-Apl-003843	Anas platyrhynchos	61.07	0.00e+00	1191.00
IUUC-Aca-004689	Anolis carolinensis	59.98	0.00e+00	1138.00
IUUC-Ame-010673	Astyanax mexicanus	71.69	0.00e+00	656.00
IUUC-Bta-012434	Bos taurus	81.57	0.00e+00	1718.00
IUUC-Cja-019625	Callithrix jacchus	83.44	0.00e+00	1744.00
IUUC-Cfa-020038	Canis familiaris	83.29	0.00e+00	1793.00
IUUC-Cpo-021503	Cavia porcellus	75.52	0.00e+00	1628.00
IUUC-Cre-022697	Chlamydomonas reinhardtii	24.51	1.00e-18	90.50
IUUC-Csa-024021	Chlorocebus sabaeus	82.02	0.00e+00	1730.00
IUUC-Cho-024769	Choloepus hoffmanni	82.60	0.00e+00	1219.00
IUUC-Dre-028438	Danio rerio	70.48	0.00e+00	637.00
IUUC-Dno-029317	Dasypus novemcinctus	81.09	0.00e+00	1679.00
IUUC-Dor-030249	Dipodomys ordii	95.23	0.00e+00	795.00
IUUC-Ete-032403	Echinops telfairi	79.17	0.00e+00	1685.00
IUUC-Eca-033216	Equus caballus	82.60	0.00e+00	1774.00
IUUC-Eeu-035319	Erinaceus europaeus	62.97	5.00e-169	588.00
IUUC-Fca-036414	Felis catus	83.93	0.00e+00	1793.00
IUUC-Fal-036886	Ficedula albicollis	60.39	0.00e+00	1234.00
IUUC-Gmo-038617	Gadus morhua	74.24	3.00e-169	587.00
IUUC-Gga-040930	Gallus gallus	61.64	0.00e+00	1241.00
IUUC-Gac-041515	Gasterosteus aculeatus	78.93	3.00e-174	603.00
IUUC-Ggo-045573	Gorilla gorilla	82.96	0.00e+00	1756.00
IUUC-Hsa-046741	Homo sapiens	82.96	0.00e+00	1754.00
IUUC-Itr-048229	Ictidomys tridecemlineatus	67.04	0.00e+00	1318.00
IUUC-Lch-049932	Latimeria chalumnae	49.33	0.00e+00	936.00
IUUC-Lpe-051572	Leersia perrieri	33.53	7.00e-39	156.00
IUUC-Loc-052180	Lepisosteus oculatus	59.73	0.00e+00	854.00
IUUC-Mcc-054918	Macaca mulatta	82.30	0.00e+00	1738.00
IUUC-Meu-056802	Macropus eugenii	59.05	0.00e+00	1104.00
IUUC-Mtr-058682	Medicago truncatula	29.11	1.00e-33	139.00
IUUC-Mga-059684	Meleagris gallopavo	60.41	0.00e+00	1166.00
IUUC-Mmr-060991	Microcebus murinus	79.52	0.00e+00	1388.00
IUUC-Mdo-062636	Monodelphis domestica	63.64	0.00e+00	1251.00
IUUC-Mmu-063910	Mus musculus	74.53	0.00e+00	1567.00
IUUC-Mac-064469	Musa acuminata	33.71	2.00e-19	92.00
IUUC-Mpu-065796	Mustela putorius furo	78.10	0.00e+00	1608.00
IUUC-Nle-069276	Nomascus leucogenys	82.21	0.00e+00	1665.00
IUUC-Opr-070545	Ochotona princeps	71.22	0.00e+00	822.00
IUUC-Ont-072449	Oreochromis niloticus	54.64	0.00e+00	710.00
IUUC-Oan-073493	Ornithorhynchus anatinus	58.54	0.00e+00	990.00
IUUC-Ocu-074445	Oryctolagus cuniculus	79.21	0.00e+00	1694.00
IUUC-Oba-075174	Oryza barthii	30.84	1.00e-34	142.00
IUUC-Ogl-077138	Oryza glaberrima	32.74	2.00e-39	158.00
IUUC-Ogu-078705	Oryza glumaepatula	30.84	8.00e-35	143.00
IUUC-Oin-079125	Oryza indica	32.74	2.00e-39	159.00
IUUC-Olo-080872	Oryza longistaminata	30.84	7.00e-35	143.00
IUUC-Ome-081864	Oryza meridionalis	30.84	2.00e-34	142.00
IUUC-Oni-082109	Oryza nivara	30.84	8.00e-35	143.00
IUUC-Oru-084310	Oryza rufipogon	30.84	8.00e-35	143.00
IUUC-Osa-085583	Oryza sativa	31.56	1.00e-39	157.00
IUUC-Ola-087574	Oryzias latipes	71.32	2.00e-167	581.00
IUUC-Oga-087977	Otolemur garnettii	80.12	0.00e+00	1622.00
IUUC-Oar-089584	Ovis aries	81.38	0.00e+00	1692.00
IUUC-Ptr-091610	Pan troglodytes	82.77	0.00e+00	1724.00
IUUC-Pan-091828	Papio anubis	78.60	0.00e+00	1604.00
IUUC-Psi-093643	Pelodiscus sinensis	63.87	0.00e+00	1305.00
IUUC-Ppa-095930	Physcomitrella patens	31.25	2.00e-40	162.00
IUUC-Pfo-096829	Poecilia formosa	62.88	0.00e+00	635.00
IUUC-Pab-098190	Pongo abelii	82.68	0.00e+00	1716.00
IUUC-Pca-100356	Procavia capensis	77.46	0.00e+00	924.00
IUUC-Pva-102372	Pteropus vampyrus	75.72	0.00e+00	1551.00
IUUC-Rno-105609	Rattus norvegicus	65.04	0.00e+00	796.00
IUUC-Sha-107092	Sarcophilus harrisii	64.72	0.00e+00	1306.00
IUUC-Sar-113376	Sorex araneus	71.64	0.00e+00	843.00
IUUC-Ssc-115969	Sus scrofa	82.88	0.00e+00	1686.00
IUUC-Tgu-117134	Taeniopygia guttata	73.49	0.00e+00	1105.00
IUUC-Tru-117981	Takifugu rubripes	71.78	3.00e-170	591.00
IUUC-Tsy-119297	Tarsius syrichta	74.16	0.00e+00	1492.00
IUUC-Tni-120116	Tetraodon nigroviridis	77.75	1.00e-172	598.00
IUUC-Tbe-127607	Tupaia belangeri	77.17	0.00e+00	1593.00
IUUC-Ttr-128647	Tursiops truncatus	82.38	0.00e+00	1638.00
IUUC-Vpa-130288	Vicugna pacos	79.61	0.00e+00	1693.00
IUUC-Xtr-132277	Xenopus tropicalis	63.64	0.00e+00	930.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence