iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035747

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02032545

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000004785.3	ENSFCAT00000004786.3	ENSFCAP00000004422.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	67.50	8.00e-158	554.00	IUUC-Hsa-045735

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

MAAVAAPWGR QREEARALGR AVRLLERLEE HFGDPRLFWH AELALKIHAN PAELVQGRMR 60
PGFSCSPGGA AGGGWGIAGL VGSASLSFPE EETEQARCQR EPRGPAQALR AHPCRRQLAK 120

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Nucleotide Sequence
(Fasta)

ATGGCCGCGG TGGCAGCCCC CTGGGGGCGG CAGCGGGAAG AGGCCCGCGC GCTCGGCCGG 60
GCGGTGAGGC TGCTGGAACG CCTGGAAGAG CACTTCGGGG ACCCCCGGCT GNNNNNNNNN 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0045121--C:membrane raft
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006508--P:proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	71.54	0.00e+00	652.00
IUUC-Bta-012705	Bos taurus	64.09	3.00e-161	561.00
IUUC-Cja-019179	Callithrix jacchus	65.14	2.00e-154	539.00
IUUC-Cfa-020593	Canis familiaris	79.33	2.00e-175	608.00
IUUC-Cpo-021289	Cavia porcellus	73.86	7.00e-135	473.00
IUUC-Csa-023966	Chlorocebus sabaeus	63.42	1.00e-155	543.00
IUUC-Dor-030246	Dipodomys ordii	60.46	2.00e-93	336.00
IUUC-Eca-033921	Equus caballus	58.71	3.00e-124	438.00
IUUC-Ggo-044622	Gorilla gorilla	77.92	4.00e-146	510.00
IUUC-Hsa-045735	Homo sapiens	67.20	2.00e-158	551.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	72.68	5.00e-153	533.00
IUUC-Laf-053983	Loxodonta africana	64.51	2.00e-165	575.00
IUUC-Mmr-061310	Microcebus murinus	62.55	2.00e-153	535.00
IUUC-Mmu-064155	Mus musculus	57.60	4.00e-156	544.00
IUUC-Mpu-066655	Mustela putorius furo	66.28	4.00e-173	600.00
IUUC-Mlu-067929	Myotis lucifugus	82.82	7.00e-134	469.00
IUUC-Nle-070065	Nomascus leucogenys	54.82	9.00e-115	406.00
IUUC-Ocu-074049	Oryctolagus cuniculus	71.68	2.00e-122	432.00
IUUC-Oga-087952	Otolemur garnettii	66.82	2.00e-164	572.00
IUUC-Oar-089382	Ovis aries	62.82	4.00e-154	537.00
IUUC-Ptr-090579	Pan troglodytes	64.44	4.00e-115	407.00
IUUC-Pan-092075	Papio anubis	66.06	2.00e-152	532.00
IUUC-Ppa-095308	Physcomitrella patens	27.71	6.00e-07	47.40
IUUC-Pab-098100	Pongo abelii	59.17	3.00e-128	451.00
IUUC-Pca-100830	Procavia capensis	58.04	6.00e-72	265.00
IUUC-Pva-102714	Pteropus vampyrus	60.94	1.00e-123	436.00
IUUC-Rno-105348	Rattus norvegicus	57.85	4.00e-150	524.00
IUUC-Sha-107138	Sarcophilus harrisii	65.85	6.00e-116	410.00
IUUC-Ssc-116424	Sus scrofa	66.34	7.00e-173	600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence