iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021682

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02053201

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008086.3	ENSCPOT00000008161.2	ENSCPOP00000007271.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.80e-55	180.1	368	406
UBD/Beta-Prp	1.40e-64	218.1	240	439

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 368  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 406
           9**********999******************9999875 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           +v++ ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++s
   Q: 240  DVDW-QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWS 327
           3333.444445555555555555555555555555555555555555555555555555555555555555555555555555554444 PP
   S: 104  p........sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           p        +    l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +
   Q: 328  PtgpatsnpNAnIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TGGI 413
           433333222111344555555555555555555555.5555555555555555555555555555555555555555555554..5555 PP
   S: 184  yslsfdsngkelvsgsldgtvklwdl 209
             + ++  g  + + + dg+v + dl
   Q: 414  FEVCWNARGDKVGASASDGSVCVLDL 439
           55555555555555555555544444 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

LSQDGTVFDG RPIESLSLID AVMPDVVQTR QQAFREKLAQ QQASAASQQN PPKNGEATVN 60
GEENGAHAIN NHSKPMEIDG DVEIPSSKAT VLRGHESEVF ICAWNPVSDL LASGSGDSTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCCCAGG ATGGCACGGT GTTTGACGGC CGCCCCATAG AGTCCCTGTC CCTGATCGAC 60
GCGGTGATGC CCGACGTGGT GCAGACCCGG CAGCAGGCGT TCCGGGAGAA GCTCGCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002514	Amborella trichopoda	64.56	1.00e-142	499.00
IUUC-Aly-005622	Arabidopsis lyrata	56.10	2.00e-119	422.00
IUUC-Ath-007137	Arabidopsis thaliana	59.23	2.00e-120	426.00
IUUC-Bol-016277	Brassica oleracea	57.59	1.00e-125	443.00
IUUC-Bra-016944	Brassica rapa	57.59	3.00e-125	442.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.71	2.00e-131	462.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	2.00e-30	127.00
IUUC-Dme-031939	Drosophila melanogaster	82.02	6.00e-176	610.00
IUUC-Gma-043369	Glycine max	62.36	4.00e-135	474.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	98.92	0.00e+00	770.00
IUUC-Kpa-049338	Komagataella pastoris	28.00	1.00e-31	130.00
IUUC-Lpe-051084	Leersia perrieri	62.09	3.00e-134	472.00
IUUC-Meu-056563	Macropus eugenii	91.60	6.00e-129	453.00
IUUC-Mtr-058624	Medicago truncatula	60.44	2.00e-126	446.00
IUUC-Mvi-060557	Microbotryum violaceum	37.04	6.00e-70	258.00
IUUC-Mlu-067852	Myotis lucifugus	91.31	0.00e+00	858.00
IUUC-Obr-076718	Oryza brachyantha	61.66	2.00e-135	475.00
IUUC-Olo-080427	Oryza longistaminata	62.18	5.00e-129	454.00
IUUC-Ppa-095868	Physcomitrella patens	66.02	8.00e-139	487.00
IUUC-Pop-098989	Populus trichocarpa	58.15	5.00e-129	454.00
IUUC-Ppe-101572	Prunus persica	63.69	4.00e-127	448.00
IUUC-Smo-109301	Selaginella moellendorffii	63.49	3.00e-141	495.00
IUUC-Sit-110710	Setaria italica	62.16	7.00e-140	490.00
IUUC-Sly-111336	Solanum lycopersicum	58.50	2.00e-130	459.00
IUUC-Sbi-114420	Sorghum bicolor	61.39	1.00e-139	490.00
IUUC-Sre-115175	Sporisorium reilianum	40.07	1.00e-56	214.00
IUUC-Tsy-118853	Tarsius syrichta	78.32	4.00e-178	617.00
IUUC-Tca-121739	Theobroma cacao	54.29	4.00e-124	438.00
IUUC-Tae-125368	Triticum aestivum	59.38	1.00e-134	473.00
IUUC-Tme-127126	Tuber melanosporum	37.28	5.00e-56	211.00
IUUC-Uma-129469	Ustilago maydis	43.53	7.00e-59	222.00
IUUC-Vvi-131193	Vitis vinifera	57.39	2.00e-129	456.00
IUUC-Yli-134648	Yarrowia lipolytica	30.31	2.00e-41	164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence