iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106680

Ensembl Protein ID

ENSSHAP00000002885.1

UniProt Accession

G3VI81; G3VI81_SARHA

Genbank Protein ID

ENSSHAP00000002885

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01103846

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002554.1	ENSSHAT00000002918.1	ENSSHAP00000002885.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-36	121.9	184	221
UBD/Beta-Prp	1.20e-52	179.1	336	544

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 184  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 221
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 63   dgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...............tls 134
           +g++l tgs+D++i+ +   ++ ++ +  l+ h+d+v s++fs +gd+++sGs+d t+r+w+ e+ ++ +                 ++
   Q: 336  KGEFLKTGSTDHVIRMYflGFEMPEKIAELESHTDKVDSIQFSNNGDRFLSGSRDGTARIWKFEQPEWKSIlldmatrlssdscseEEK 424
           23488899999999999888889999999999999999999999999999999999999999999999888899999999998877666 PP
   S: 135  ghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlq....tgecvr 216
             +  v++++++ ++ l+v++ +D ++++W++ tg+ll+ l g htd v  l+   fds  + ++s+++dg + +wd+     t++  +
   Q: 425  FMKPKVTMIAWNRNDTLVVTAVNDHVLKVWNSHTGQLLHNLVG-HTDEVFVLEthpFDS--RIMLSAGHDGNIFIWDITkgikTKHYFN 510
           6677889999999999999999999999999999999999988.999999999544444..8899999999999999985655555544 PP
   S: 217  tlnght.dnvksvrfspnderlvsgssDgsiriW 249
             +g+    v + +fs+++++++++ s+g + i+
   Q: 511  MIEGQGhGAVFDCKFSSDGQHFACTDSHGHLLIF 544
           4444322556667888888888888888877765 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAEHSASRHP VPPIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHD 60
WKYEDLVLSN KHVAPDHLLQ ICQRIGPILD KEIPPCISRV TSLLGAGRQS LLRTAKDCRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGGGAGGG TCAGTCACGT GACGGCCGCC TAAGTCCCGA TGCTCGTTCT TGCCAACTGC 60
CCGGAGCAAG GGGCTCCATC AGGGCAGAGA AAAATTTGCA ACTGTCTCCC TTCGAGAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002600	Amborella trichopoda	29.36	2.00e-68	255.00
IUUC-Aca-004348	Anolis carolinensis	61.58	0.00e+00	2006.00
IUUC-Aly-006517	Arabidopsis lyrata	30.54	3.00e-72	267.00
IUUC-Ath-006577	Arabidopsis thaliana	30.39	7.00e-72	266.00
IUUC-Bdi-014797	Brachypodium distachyon	29.84	7.00e-59	223.00
IUUC-Bol-015737	Brassica oleracea	29.72	2.00e-71	265.00
IUUC-Bra-017961	Brassica rapa	29.68	9.00e-71	262.00
IUUC-Cfa-021037	Canis familiaris	88.60	0.00e+00	1449.00
IUUC-Cpo-021934	Cavia porcellus	82.23	0.00e+00	2461.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	33.22	6.00e-34	139.00
IUUC-Cho-024690	Choloepus hoffmanni	90.06	0.00e+00	704.00
IUUC-Csv-025813	Ciona savignyi	43.61	1.00e-179	623.00
IUUC-Dre-028205	Danio rerio	68.65	0.00e+00	1142.00
IUUC-Dno-028938	Dasypus novemcinctus	68.95	0.00e+00	2744.00
IUUC-Dor-030444	Dipodomys ordii	77.94	0.00e+00	736.00
IUUC-Dme-031752	Drosophila melanogaster	49.92	0.00e+00	666.00
IUUC-Fca-035485	Felis catus	90.28	0.00e+00	1368.00
IUUC-Gga-040865	Gallus gallus	76.22	0.00e+00	2258.00
IUUC-Gma-043340	Glycine max	31.39	1.00e-71	265.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	84.18	0.00e+00	1007.00
IUUC-Lch-049662	Latimeria chalumnae	78.31	0.00e+00	1326.00
IUUC-Lpe-051619	Leersia perrieri	31.40	5.00e-68	253.00
IUUC-Laf-053848	Loxodonta africana	81.20	0.00e+00	2439.00
IUUC-Meu-056739	Macropus eugenii	86.48	0.00e+00	1206.00
IUUC-Mtr-058094	Medicago truncatula	31.64	2.00e-73	271.00
IUUC-Mdo-062074	Monodelphis domestica	85.11	0.00e+00	3474.00
IUUC-Mac-065343	Musa acuminata	31.20	4.00e-75	276.00
IUUC-Mpu-066643	Mustela putorius furo	74.14	0.00e+00	2503.00
IUUC-Oan-072954	Ornithorhynchus anatinus	71.93	0.00e+00	2802.00
IUUC-Oba-075709	Oryza barthii	30.10	8.00e-59	223.00
IUUC-Obr-076619	Oryza brachyantha	30.54	3.00e-68	254.00
IUUC-Ogl-077493	Oryza glaberrima	27.27	7.00e-30	127.00
IUUC-Opu-083233	Oryza punctata	30.39	3.00e-63	238.00
IUUC-Oru-085195	Oryza rufipogon	30.10	1.00e-58	222.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.09	1.00e-54	209.00
IUUC-Oga-087938	Otolemur garnettii	65.10	0.00e+00	2467.00
IUUC-Psi-093271	Pelodiscus sinensis	62.66	0.00e+00	2278.00
IUUC-Pma-094427	Petromyzon marinus	65.43	4.00e-132	463.00
IUUC-Ppa-095793	Physcomitrella patens	29.24	2.00e-72	268.00
IUUC-Pop-099672	Populus trichocarpa	30.75	2.00e-72	268.00
IUUC-Ppe-101849	Prunus persica	30.51	9.00e-73	269.00
IUUC-Pva-102782	Pteropus vampyrus	69.74	0.00e+00	2699.00
IUUC-Sly-111348	Solanum lycopersicum	30.90	2.00e-75	278.00
IUUC-Sbi-114195	Sorghum bicolor	29.34	6.00e-58	218.00
IUUC-Tsy-118921	Tarsius syrichta	79.71	0.00e+00	1278.00
IUUC-Tca-121615	Theobroma cacao	30.30	1.00e-67	252.00
IUUC-Tae-125478	Triticum aestivum	30.59	3.00e-70	261.00
IUUC-Tur-126809	Triticum urartu	30.40	6.00e-68	253.00
IUUC-Ttr-128561	Tursiops truncatus	81.41	0.00e+00	1338.00
IUUC-Vpa-130444	Vicugna pacos	62.26	0.00e+00	1330.00
IUUC-Vvi-131362	Vitis vinifera	29.97	3.00e-71	264.00
IUUC-Xma-133633	Xiphophorus maculatus	63.58	0.00e+00	1115.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence