iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002061

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01017260

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000004446.1	ENSAMET00000004961.1	ENSAMEP00000004769.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.90e-18	66.5	295	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 295  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 342
           8*********88.6*******************.*******7.******75 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAGAGPGGYA AEFVPPPECP VFEPSWEEFT DPLSFIGRIR PLAEKTGICK IRPPKDWQPP 60
FACEVKSFRF TPRVQRLNEL EAMTRVRLDF LDQLAKFWEL QGSTLKIPVV ERKILDLYAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGCG CGGGGCCGGG GGGCTATGCG GCAGAGTTTG TGCCACCTCC CGAGTGCCCA 60
GTCTTTGAGC CCAGCTGGGA GGAGTTCACG GACCCGCTCA GCTTTATCGG CCGCATCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

aml:100476032

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002595	Amborella trichopoda	30.90	6.00e-125	442.00
IUUC-Apl-004141	Anas platyrhynchos	92.12	0.00e+00	2829.00
IUUC-Aca-004952	Anolis carolinensis	90.78	0.00e+00	2848.00
IUUC-Ani-009139	Aspergillus nidulans	32.98	3.00e-108	387.00
IUUC-Ate-010453	Aspergillus terreus	29.43	5.00e-117	416.00
IUUC-Ame-011323	Astyanax mexicanus	76.88	0.00e+00	2075.00
IUUC-Bgr-012241	Blumeria graminis	30.23	5.00e-115	409.00
IUUC-Bta-012902	Bos taurus	98.14	0.00e+00	2990.00
IUUC-Bdi-014050	Brachypodium distachyon	30.10	2.00e-120	428.00
IUUC-Cja-018988	Callithrix jacchus	96.44	0.00e+00	2813.00
IUUC-Cfa-020212	Canis familiaris	98.86	0.00e+00	2971.00
IUUC-Cpo-022221	Cavia porcellus	97.59	0.00e+00	2107.00
IUUC-Csa-023575	Chlorocebus sabaeus	98.87	0.00e+00	2890.00
IUUC-Cho-024280	Choloepus hoffmanni	93.46	0.00e+00	2759.00
IUUC-Cin-025321	Ciona intestinalis	48.51	0.00e+00	1076.00
IUUC-Csv-026185	Ciona savignyi	48.05	0.00e+00	1171.00
IUUC-Dre-027909	Danio rerio	76.07	0.00e+00	1665.00
IUUC-Dno-029473	Dasypus novemcinctus	98.25	0.00e+00	2735.00
IUUC-Dor-030281	Dipodomys ordii	96.31	0.00e+00	1237.00
IUUC-Dme-032021	Drosophila melanogaster	47.54	0.00e+00	1132.00
IUUC-Eca-034265	Equus caballus	98.33	0.00e+00	3009.00
IUUC-Fca-035476	Felis catus	98.86	0.00e+00	3003.00
IUUC-Fal-037078	Ficedula albicollis	91.87	0.00e+00	2489.00
IUUC-Ggr-039929	Gaeumannomyces graminis	30.23	2.00e-110	394.00
IUUC-Gga-040466	Gallus gallus	91.09	0.00e+00	2898.00
IUUC-Gac-042566	Gasterosteus aculeatus	75.80	0.00e+00	2126.00
IUUC-Ggo-044524	Gorilla gorilla	91.85	0.00e+00	2533.00
IUUC-Hsa-045821	Homo sapiens	98.68	0.00e+00	2989.00
IUUC-Kpa-049245	Komagataella pastoris	23.17	5.00e-40	160.00
IUUC-Lch-050630	Latimeria chalumnae	74.78	0.00e+00	2126.00
IUUC-Loc-051963	Lepisosteus oculatus	76.49	0.00e+00	2083.00
IUUC-Laf-053918	Loxodonta africana	91.58	0.00e+00	2585.00
IUUC-Mcc-055672	Macaca mulatta	97.28	0.00e+00	2990.00
IUUC-Mor-057198	Magnaporthe oryzae	30.80	3.00e-120	427.00
IUUC-Mpo-057317	Magnaporthe poae	30.12	1.00e-111	398.00
IUUC-Mga-059192	Meleagris gallopavo	83.06	0.00e+00	2456.00
IUUC-Mmr-060968	Microcebus murinus	96.74	0.00e+00	3004.00
IUUC-Mdo-062945	Monodelphis domestica	95.75	0.00e+00	2805.00
IUUC-Mmu-063614	Mus musculus	96.76	0.00e+00	2933.00
IUUC-Mpu-066349	Mustela putorius furo	99.69	0.00e+00	2880.00
IUUC-Mlu-067363	Myotis lucifugus	98.98	0.00e+00	3078.00
IUUC-Nle-070142	Nomascus leucogenys	98.68	0.00e+00	2989.00
IUUC-Opr-071002	Ochotona princeps	91.45	0.00e+00	1422.00
IUUC-Ont-072471	Oreochromis niloticus	78.31	0.00e+00	1896.00
IUUC-Oan-072797	Ornithorhynchus anatinus	79.54	0.00e+00	2041.00
IUUC-Ocu-074164	Oryctolagus cuniculus	97.24	0.00e+00	3045.00
IUUC-Oba-075388	Oryza barthii	27.95	1.00e-83	305.00
IUUC-Obr-076296	Oryza brachyantha	34.43	5.00e-97	350.00
IUUC-Ogu-079040	Oryza glumaepatula	28.00	6.00e-84	306.00
IUUC-Ome-081764	Oryza meridionalis	29.90	7.00e-102	366.00
IUUC-Oni-083012	Oryza nivara	27.91	3.00e-83	304.00
IUUC-Oru-084630	Oryza rufipogon	27.60	9.00e-83	302.00
IUUC-Ola-087076	Oryzias latipes	75.29	0.00e+00	2113.00
IUUC-Oga-088350	Otolemur garnettii	96.22	0.00e+00	2916.00
IUUC-Oar-090045	Ovis aries	98.14	0.00e+00	2992.00
IUUC-Ptr-091199	Pan troglodytes	98.14	0.00e+00	2974.00
IUUC-Pan-092094	Papio anubis	94.13	0.00e+00	2916.00
IUUC-Psi-093550	Pelodiscus sinensis	91.50	0.00e+00	2776.00
IUUC-Pma-094137	Petromyzon marinus	52.73	0.00e+00	1296.00
IUUC-Pno-094879	Phaeosphaeria nodorum	29.58	3.00e-119	423.00
IUUC-Ppa-095839	Physcomitrella patens	35.20	5.00e-16	81.30
IUUC-Pfo-097266	Poecilia formosa	78.35	0.00e+00	1875.00
IUUC-Pab-098576	Pongo abelii	98.86	0.00e+00	2984.00
IUUC-Pca-100123	Procavia capensis	94.64	0.00e+00	1658.00
IUUC-Ppe-101504	Prunus persica	32.45	3.00e-103	370.00
IUUC-Pva-103109	Pteropus vampyrus	93.16	0.00e+00	2839.00
IUUC-Pgr-103434	Puccinia graminis	27.88	5.00e-38	151.00
IUUC-Pte-104195	Pyrenophora teres	30.14	4.00e-123	436.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	30.24	4.00e-125	443.00
IUUC-Rno-105664	Rattus norvegicus	96.76	0.00e+00	2932.00
IUUC-Sha-107506	Sarcophilus harrisii	94.14	0.00e+00	2568.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	20.99	2.00e-35	144.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.92	3.00e-53	204.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	9.00e-11	62.40
IUUC-Sit-110534	Setaria italica	29.86	8.00e-122	432.00
IUUC-Sar-113052	Sorex araneus	97.66	0.00e+00	2991.00
IUUC-Tgu-116613	Taeniopygia guttata	91.19	0.00e+00	2828.00
IUUC-Tru-118604	Takifugu rubripes	75.44	0.00e+00	2164.00
IUUC-Tsy-119237	Tarsius syrichta	98.79	0.00e+00	1317.00
IUUC-Tni-120779	Tetraodon nigroviridis	75.02	0.00e+00	2138.00
IUUC-Tca-121478	Theobroma cacao	32.51	1.00e-106	382.00
IUUC-Tae-125894	Triticum aestivum	29.64	2.00e-112	401.00
IUUC-Tme-127087	Tuber melanosporum	30.97	8.00e-133	469.00
IUUC-Tbe-127627	Tupaia belangeri	98.99	0.00e+00	807.00
IUUC-Ttr-129242	Tursiops truncatus	96.64	0.00e+00	2895.00
IUUC-Uma-129590	Ustilago maydis	30.35	1.00e-133	471.00
IUUC-Vda-129733	Verticillium dahliae	29.08	2.00e-106	381.00
IUUC-Vpa-130429	Vicugna pacos	90.95	0.00e+00	1474.00
IUUC-Xtr-131762	Xenopus tropicalis	76.57	0.00e+00	2274.00
IUUC-Xma-133693	Xiphophorus maculatus	75.08	0.00e+00	2141.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence