iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gma-044020

Ensembl Protein ID

GLYMA13G17830.3

UniProt Accession

P69325; O82079; P03993; UBIQP_SOYBN

Genbank Protein ID

BAA03764.1; CAA31627.1

Protein Name

Polyubiquitin; Ubiquitin

Genbank Nucleotide ID

D16248; X13251

Gene Name

SUBI-1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GLYMA13G17830	GLYMA13G17830.3	GLYMA13G17830.3
GLYMA13G17830	GLYMA13G17830.1	GLYMA13G17830.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/NEDD8	1.30e-165	539.6	229	304
ULD/UDP/UBQ/UBQ_PIM	4.90e-113	370.9	229	301

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/NEDD8

   S: 1    mlikvktLtgkeieieieesdtierikerveekeGiPPsqqrliyaGkqleddktaadynlekgsvLhLvLaLrGG 76
           m+i+vktLtgk+i++e+e+sdti+++k+++++keGiPP+qqrli+aGkqled++t+adyn++k+s+LhLvL+LrGG
   Q: 229  MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGG 304
           89*************************************************************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkk 73
           m+++vktl+gk+++lev+++dt+ ++K+ki+++ g+pp+qq+LI+aGk+L+D +tL +++i+++s++hlv++ 
   Q: 229  MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRL 301
           99********************************************************************986 PP

Organism

Glycine max

Functional Description
(View)

Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).

Protein Sequence
(Fasta)

MQIFVKTLTG KTITLEVESS DTIDNVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLADYN 60
IQKESTLHLV LRLRGGMQIF VKTLTGKTIT LEVESSDTID NVKAKIQDKE GIPPDQQRLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTCTTTAT CTTGGCGTGT GTCAATGACC CCCACCATAC ACGTGGCAAA TCTTTATTCG 60
TTGACTTTTG GATATTTTCG TCATTGTGAC ATCGCAACCA AGCTATAAGT ACGACCCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation

Interpro

IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2

Pfam

PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus

KEGG

gmx:100791065; gmx:100799042; gmx:547906

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006259	Arabidopsis lyrata	100.00	2.00e-174	604.00
IUUC-Ang-009646	Aspergillus niger	97.37	4.00e-170	590.00
IUUC-Bdi-015064	Brachypodium distachyon	100.00	9.00e-174	602.00
IUUC-Bol-016524	Brassica oleracea	100.00	2.00e-174	604.00
IUUC-Dor-031044	Dipodomys ordii	94.96	8.00e-74	268.00
IUUC-Mga-059240	Meleagris gallopavo	93.83	3.00e-85	306.00
IUUC-Opr-070947	Ochotona princeps	95.63	6.00e-125	439.00
IUUC-Olo-080418	Oryza longistaminata	33.62	3.00e-30	125.00
IUUC-Ppa-095173	Physcomitrella patens	98.69	3.00e-172	597.00
IUUC-Pfo-096371	Poecilia formosa	87.45	5.00e-126	443.00
IUUC-Sbi-114343	Sorghum bicolor	100.00	9.00e-174	602.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence