iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppa-095494

Ensembl Protein ID

PP1S28_22V6.1

UniProt Accession

A9RTN5; A9RTN5_PHYPA

Genbank Protein ID

EDQ77623.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

DS544917

Gene Name

PHYPADRAFT_178002

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S28_22V6	PP1S28_22V6.1	PP1S28_22V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-10	41.4	78	117

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH++ v+c++   d t+lv++s D t+k+WD  tgv+l+s
   Q: 78   GHNGAVWCCDVsRDsTRLVTSSADQTVKLWDCETGVQLHS 117
           8***********777*********************9986 PP

Organism

Physcomitrella patens

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MEDGNANSTQ TVRGNKSLHV GGGGKLSRMR PILLKGHERP LTFLKYNRDG DLLFSCAKDH 60
TPTVWYASNG ERLGTYKGHN GAVWCCDVSR DSTRLVTSSA DQTVKLWDCE TGVQLHSFNF 120

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Nucleotide Sequence
(Fasta)

ATGGAAGATG GTAACGCTAA CAGTACCCAA ACAGTTCGTG GCAACAAAAG TCTTCACGTC 60
GGAGGTAATG CCCTCAAGGT CGTGTAAAGG TGGATCACAA AGTCCACCTT CAAACGCATG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

ppp:PHYPADRAFT_178002

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence