iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021691

Ensembl Protein ID

ENSCPOP00000008049.2

UniProt Accession

H0VDJ2; H0VDJ2_CAVPO

Genbank Protein ID

ENSCPOP00000008049

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02053547

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008955.3	ENSCPOT00000009037.2	ENSCPOP00000008049.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	78.96	0.00e+00	1808.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSSTGQDSTT TRHRRSRHNP QSPLHDSSVT SKRNTKKGAV PRSSPNLAEV KKKGKMKKLS 60
QAVEDDLIIG FQELDVNPEA KIAVGTGLVF DEQLNEFHCL WDDSFPERPE RLHAIKEQLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTCCA CTGGCCAGGA TTCCACTACA ACCAGGCATC GAAGGAGTAG GCACAACCCC 60
CAGTCACCTC TTCACGACTC CAGCGTCACT TCGGTGAGGT CCCCGACCTG CCCTGATGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	42.04	2.00e-70	260.00
IUUC-Aml-002087	Ailuropoda melanoleuca	80.14	0.00e+00	1802.00
IUUC-Atr-002745	Amborella trichopoda	45.28	2.00e-83	303.00
IUUC-Aca-004303	Anolis carolinensis	57.77	0.00e+00	972.00
IUUC-Aly-006432	Arabidopsis lyrata	45.82	2.00e-78	287.00
IUUC-Ath-007355	Arabidopsis thaliana	46.30	2.00e-82	300.00
IUUC-Ago-007972	Ashbya gossypii	41.83	2.00e-80	293.00
IUUC-Acl-008187	Aspergillus clavatus	44.47	7.00e-82	298.00
IUUC-Afl-008399	Aspergillus flavus	53.33	8.00e-43	167.00
IUUC-Afu-008954	Aspergillus fumigatus	40.72	7.00e-71	261.00
IUUC-Ani-009142	Aspergillus nidulans	41.42	3.00e-72	266.00
IUUC-Ang-009522	Aspergillus niger	37.01	4.00e-44	172.00
IUUC-Aor-010069	Aspergillus oryzae	43.60	6.00e-73	268.00
IUUC-Ate-010291	Aspergillus terreus	42.29	5.00e-81	295.00
IUUC-Ame-010780	Astyanax mexicanus	51.62	0.00e+00	777.00
IUUC-Bta-013052	Bos taurus	74.91	0.00e+00	1670.00
IUUC-Bci-013789	Botrytis cinerea	40.00	3.00e-77	283.00
IUUC-Bdi-014007	Brachypodium distachyon	44.34	8.00e-83	301.00
IUUC-Bol-015468	Brassica oleracea	46.88	3.00e-80	292.00
IUUC-Bra-016680	Brassica rapa	47.19	8.00e-81	294.00
IUUC-Cel-018220	Caenorhabditis elegans	38.16	6.00e-147	514.00
IUUC-Cja-019473	Callithrix jacchus	74.14	0.00e+00	1679.00
IUUC-Cfa-020263	Canis familiaris	79.62	0.00e+00	1741.00
IUUC-Csa-024223	Chlorocebus sabaeus	78.13	0.00e+00	1769.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	41.28	8.00e-74	271.00
IUUC-Cne-026978	Cryptococcus neoformans	44.18	3.00e-84	306.00
IUUC-Dre-028820	Danio rerio	57.58	0.00e+00	904.00
IUUC-Dno-029160	Dasypus novemcinctus	71.60	0.00e+00	1560.00
IUUC-Dor-030859	Dipodomys ordii	71.10	0.00e+00	1630.00
IUUC-Dse-031186	Dothistroma septosporum	42.25	1.00e-75	277.00
IUUC-Dme-031963	Drosophila melanogaster	43.85	0.00e+00	666.00
IUUC-Ete-032279	Echinops telfairi	65.71	1.00e-154	540.00
IUUC-Eca-033842	Equus caballus	79.06	0.00e+00	1828.00
IUUC-Eeu-034487	Erinaceus europaeus	76.02	4.00e-153	535.00
IUUC-Fca-036430	Felis catus	79.46	0.00e+00	1743.00
IUUC-Fox-038067	Fusarium oxysporum	43.79	1.00e-75	277.00
IUUC-Fso-038263	Fusarium solani	40.20	4.00e-76	279.00
IUUC-Ggr-040062	Gaeumannomyces graminis	42.15	4.00e-75	275.00
IUUC-Gma-043738	Glycine max	48.45	9.00e-85	307.00
IUUC-Ggo-045022	Gorilla gorilla	78.13	0.00e+00	1763.00
IUUC-Hsa-046904	Homo sapiens	78.05	0.00e+00	1761.00
IUUC-Hvu-047285	Hordeum vulgare	45.91	2.00e-83	302.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	83.32	0.00e+00	1863.00
IUUC-Kpa-049281	Komagataella pastoris	40.00	1.00e-80	294.00
IUUC-Lch-050330	Latimeria chalumnae	46.25	0.00e+00	922.00
IUUC-Lpe-051214	Leersia perrieri	45.91	3.00e-84	306.00
IUUC-Lma-053263	Leptosphaeria maculans	43.46	2.00e-86	313.00
IUUC-Laf-053386	Loxodonta africana	75.02	0.00e+00	1680.00
IUUC-Mcc-055530	Macaca mulatta	78.47	0.00e+00	1774.00
IUUC-Meu-056442	Macropus eugenii	67.59	0.00e+00	961.00
IUUC-Mor-057095	Magnaporthe oryzae	39.45	3.00e-79	289.00
IUUC-Mpo-057389	Magnaporthe poae	43.19	2.00e-75	277.00
IUUC-Mtr-058463	Medicago truncatula	46.88	1.00e-85	310.00
IUUC-Mla-059143	Melampsora laricipopulina	42.66	6.00e-80	291.00
IUUC-Mmr-060637	Microcebus murinus	79.72	0.00e+00	1861.00
IUUC-Mdo-062198	Monodelphis domestica	67.24	0.00e+00	1063.00
IUUC-Mmu-063346	Mus musculus	75.97	0.00e+00	1713.00
IUUC-Mac-064630	Musa acuminata	45.45	3.00e-83	302.00
IUUC-Mpu-065884	Mustela putorius furo	79.32	0.00e+00	1806.00
IUUC-Mlu-068117	Myotis lucifugus	78.90	0.00e+00	1749.00
IUUC-Nfi-068404	Neosartorya fischeri	44.39	3.00e-81	296.00
IUUC-Ncr-068672	Neurospora crassa	43.02	7.00e-76	278.00
IUUC-Nle-069868	Nomascus leucogenys	91.10	0.00e+00	737.00
IUUC-Opr-071074	Ochotona princeps	66.42	0.00e+00	1022.00
IUUC-Ont-072246	Oreochromis niloticus	52.79	0.00e+00	785.00
IUUC-Oan-072911	Ornithorhynchus anatinus	67.84	1.00e-106	381.00
IUUC-Ocu-074627	Oryctolagus cuniculus	80.09	0.00e+00	1818.00
IUUC-Oba-075489	Oryza barthii	45.31	6.00e-83	301.00
IUUC-Obr-076150	Oryza brachyantha	45.11	2.00e-83	303.00
IUUC-Ogl-077437	Oryza glaberrima	45.31	3.00e-83	302.00
IUUC-Ogu-078370	Oryza glumaepatula	45.62	5.00e-84	305.00
IUUC-Oin-079210	Oryza indica	45.62	5.00e-84	305.00
IUUC-Olo-080971	Oryza longistaminata	45.99	1.00e-71	264.00
IUUC-Oni-082031	Oryza nivara	45.62	1.00e-83	304.00
IUUC-Opu-083471	Oryza punctata	37.94	3.00e-83	302.00
IUUC-Oru-084755	Oryza rufipogon	45.62	5.00e-84	305.00
IUUC-Osa-085447	Oryza sativa	45.62	5.00e-84	305.00
IUUC-Oga-089155	Otolemur garnettii	78.07	0.00e+00	1781.00
IUUC-Oar-089620	Ovis aries	74.91	0.00e+00	1667.00
IUUC-Ptr-090812	Pan troglodytes	88.87	0.00e+00	1264.00
IUUC-Pan-092340	Papio anubis	78.39	0.00e+00	1768.00
IUUC-Pma-094386	Petromyzon marinus	54.40	0.00e+00	811.00
IUUC-Pno-095131	Phaeosphaeria nodorum	46.64	1.00e-72	267.00
IUUC-Ppa-095550	Physcomitrella patens	49.24	8.00e-87	315.00
IUUC-Pfo-096110	Poecilia formosa	55.51	0.00e+00	721.00
IUUC-Pab-098422	Pongo abelii	77.10	0.00e+00	1735.00
IUUC-Pop-099174	Populus trichocarpa	44.03	3.00e-78	286.00
IUUC-Pca-100833	Procavia capensis	72.66	0.00e+00	1518.00
IUUC-Ppe-101644	Prunus persica	45.31	9.00e-85	307.00
IUUC-Pva-102410	Pteropus vampyrus	71.97	0.00e+00	1563.00
IUUC-Ptt-103841	Puccinia triticina	39.80	3.00e-78	286.00
IUUC-Pte-104383	Pyrenophora teres	42.82	3.00e-82	300.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.09	9.00e-83	301.00
IUUC-Rno-105131	Rattus norvegicus	77.05	0.00e+00	1717.00
IUUC-Sce-106274	Saccharomyces cerevisiae	37.39	5.00e-82	298.00
IUUC-Sha-106661	Sarcophilus harrisii	55.31	0.00e+00	807.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	40.20	9.00e-86	311.00
IUUC-Spo-108300	Schizosaccharomyces pombe	44.38	7.00e-84	305.00
IUUC-Smo-109615	Selaginella moellendorffii	44.36	2.00e-85	310.00
IUUC-Sit-110160	Setaria italica	45.28	3.00e-79	289.00
IUUC-Sly-111164	Solanum lycopersicum	41.49	3.00e-78	286.00
IUUC-Stu-112685	Solanum tuberosum	40.40	7.00e-69	254.00
IUUC-Sar-113692	Sorex araneus	65.55	0.00e+00	749.00
IUUC-Sbi-114301	Sorghum bicolor	45.62	4.00e-79	289.00
IUUC-Sre-115013	Sporisorium reilianum	43.67	1.00e-80	294.00
IUUC-Ssc-115724	Sus scrofa	77.91	0.00e+00	1647.00
IUUC-Tgu-116605	Taeniopygia guttata	48.54	0.00e+00	665.00
IUUC-Tru-117614	Takifugu rubripes	57.18	0.00e+00	859.00
IUUC-Tsy-118807	Tarsius syrichta	66.27	0.00e+00	865.00
IUUC-Tni-119809	Tetraodon nigroviridis	55.33	0.00e+00	788.00
IUUC-Tca-121312	Theobroma cacao	45.94	2.00e-82	300.00
IUUC-Tre-121930	Trichoderma reesei	39.80	2.00e-77	283.00
IUUC-Tvi-122373	Trichoderma virens	40.30	2.00e-77	283.00
IUUC-Tae-123064	Triticum aestivum	42.69	4.00e-77	281.00
IUUC-Tme-127027	Tuber melanosporum	43.44	8.00e-71	260.00
IUUC-Tbe-127675	Tupaia belangeri	51.97	5.00e-85	309.00
IUUC-Ttr-128411	Tursiops truncatus	76.51	0.00e+00	1730.00
IUUC-Uma-129408	Ustilago maydis	45.83	7.00e-76	278.00
IUUC-Vda-129994	Verticillium dahliae	38.62	2.00e-69	257.00
IUUC-Vpa-130525	Vicugna pacos	77.66	4.00e-60	226.00
IUUC-Vvi-131038	Vitis vinifera	44.65	5.00e-84	305.00
IUUC-Xtr-132618	Xenopus tropicalis	54.55	0.00e+00	926.00
IUUC-Xma-133730	Xiphophorus maculatus	48.98	0.00e+00	702.00
IUUC-Yli-134680	Yarrowia lipolytica	42.93	2.00e-85	310.00
IUUC-Zma-135110	Zea mays	45.45	4.00e-80	292.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence