iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052936

Ensembl Protein ID

ENSLOCP00000017652.1

UniProt Accession

W5NAJ3; W5NAJ3_LEPOC

Genbank Protein ID

ENSLOCP00000017652

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01006757

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000014330.1	ENSLOCT00000017684.1	ENSLOCP00000017652.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	8.90e-224	743.3	452	932

Active Site

Position(s)	Description	Evidence
633	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Qi+++G++ qekl +++++lvGag++GcEllKn++++G+     g+i v+Dmdt+e+snlnrqFLfr++dv k K+e+aa+a+k++
   Q: 452  YDGQIAVFGSKMQEKLAKQRYFLVGAGAIGCELLKNFAMIGLasgegGEIIVTDMDTIEKSNLNRQFLFRPWDVTKMKSETAAAAVKQM 540
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           np v+++ h++++ +++e+i+   Ff+ +++V++aldn++ar++++r+c+++r+pl+esgtlG++G+v+v+i+ lte+ys+s+dpp+k+
   Q: 541  NPAVRITGHQNRVGPDTEKIYdddFFEGLHGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKS 629
           ***************************************************************************************** PP
   S: 171  iPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafak 247
           iP+ctlk++pna+eht++wa            + + ++l +++++ e++ kl  ++++e++++v ++l++  ++++e+++++a+++++ 
   Q: 630  IPICTLKNFPNAIEHTLQWArdefeglfkqpaENATQYL-TDPKFMERTLKLPGAQPLEVLEAVYKSLVTDCPRSWEDCVAWARNHWQC 717
           *****************************9999999999.78888899999************************************** PP
   S: 248  ttinsikqllksfecdivtkskspfwv......................................................sfcsnaea 282
           +++n+i+qll++f+++++t+s++pfw+                                                      +       
   Q: 718  QYSNNIRQLLHNFPPEQLTSSGAPFWSgpkrcphplafdpnndlhmdyilaaanlfahtyglqgsrdrpavvrildsvkvpE------- 799
           **********************************************************999999999996666666543332....... PP
   S: 283  lqvp......ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddli 358
                     + +++d+e ++a+a+     l+ l+  l   ++ +g k   ++fekddd   ++d++ aa+nlrae+++i+p +d+++ 
   Q: 800  ---FtpksgvKIHVSDQELQSANASvddsrLEELKSLLPGTDSLSGFKLCAIEFEKDDDTnfHMDFIVAASNLRAENYDIPP-ADRHKS 884
           ...022333355566666665555566778****************************************************.****** PP
   S: 359  keiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           k iag+iipaiatt+a+v Gl+++E++K+v+g  k e +kn f+++a+
   Q: 885  KLIAGKIIPAIATTTAAVVGLVCLELLKIVQGhkKLESYKNGFMNLAL 932
           ********************************99999******99875 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSSSPLSKKR RVSGPETKTG SHCSSANSVR TELSHNPANG MAKNGNEAEI DEGLYSRQLY 60
VLGHEAMKRM QASNVLISGM RGLGVEIAKN VILGGVKSVT VHDSGNAEWR DLSSQFYLRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGCT CGCCGCTGTC CAAGAAGCGT CGCGTGTCAG GACCAGAGAC GAAGACGGGA 60
TCTCACTGCT CCTCCGCCAA CTCTGTGAGA ACTGAACTGT CCCACAACCC TGCCAACGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0007409--P:axonogenesis
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	46.87	0.00e+00	872.00
IUUC-Aml-001311	Ailuropoda melanoleuca	79.96	0.00e+00	1777.00
IUUC-Atr-002684	Amborella trichopoda	45.16	0.00e+00	904.00
IUUC-Aca-004620	Anolis carolinensis	79.12	0.00e+00	1739.00
IUUC-Aly-005515	Arabidopsis lyrata	45.99	0.00e+00	914.00
IUUC-Ath-006891	Arabidopsis thaliana	46.58	0.00e+00	927.00
IUUC-Ago-007873	Ashbya gossypii	53.89	0.00e+00	1050.00
IUUC-Acl-008181	Aspergillus clavatus	54.64	0.00e+00	1076.00
IUUC-Afl-008455	Aspergillus flavus	54.37	0.00e+00	1036.00
IUUC-Afu-009065	Aspergillus fumigatus	55.08	0.00e+00	1099.00
IUUC-Ani-009371	Aspergillus nidulans	54.64	0.00e+00	1067.00
IUUC-Ang-009737	Aspergillus niger	54.76	0.00e+00	1083.00
IUUC-Aor-010007	Aspergillus oryzae	54.37	0.00e+00	1036.00
IUUC-Ate-010466	Aspergillus terreus	54.11	0.00e+00	1098.00
IUUC-Ame-010933	Astyanax mexicanus	88.76	0.00e+00	1864.00
IUUC-Bgr-012281	Blumeria graminis	53.17	0.00e+00	1084.00
IUUC-Bta-012767	Bos taurus	80.36	0.00e+00	1790.00
IUUC-Bci-013721	Botrytis cinerea	56.07	0.00e+00	1058.00
IUUC-Bdi-014335	Brachypodium distachyon	45.76	0.00e+00	911.00
IUUC-Bol-015161	Brassica oleracea	44.62	0.00e+00	918.00
IUUC-Bra-017252	Brassica rapa	45.08	0.00e+00	911.00
IUUC-Cel-018260	Caenorhabditis elegans	49.63	0.00e+00	982.00
IUUC-Cja-019152	Callithrix jacchus	80.45	0.00e+00	1786.00
IUUC-Cfa-020622	Canis familiaris	79.23	0.00e+00	1724.00
IUUC-Cpo-022526	Cavia porcellus	80.26	0.00e+00	1768.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	47.20	0.00e+00	891.00
IUUC-Csa-023780	Chlorocebus sabaeus	80.74	0.00e+00	1795.00
IUUC-Cin-025790	Ciona intestinalis	64.13	0.00e+00	1370.00
IUUC-Csv-026084	Ciona savignyi	61.60	0.00e+00	1357.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	54.15	0.00e+00	1102.00
IUUC-Cne-026960	Cryptococcus neoformans	57.16	0.00e+00	1132.00
IUUC-Cme-027290	Cyanidioschyzon merolae	45.02	0.00e+00	839.00
IUUC-Dre-028149	Danio rerio	89.14	0.00e+00	1907.00
IUUC-Dno-028884	Dasypus novemcinctus	80.83	0.00e+00	1795.00
IUUC-Dor-030229	Dipodomys ordii	77.05	0.00e+00	1701.00
IUUC-Dse-031524	Dothistroma septosporum	52.71	0.00e+00	1066.00
IUUC-Dme-032045	Drosophila melanogaster	61.26	0.00e+00	1296.00
IUUC-Ete-032544	Echinops telfairi	69.39	0.00e+00	735.00
IUUC-Eca-033330	Equus caballus	80.45	0.00e+00	1794.00
IUUC-Eeu-034717	Erinaceus europaeus	43.97	2.00e-169	589.00
IUUC-Fca-036255	Felis catus	80.74	0.00e+00	1781.00
IUUC-Fal-037445	Ficedula albicollis	50.21	0.00e+00	899.00
IUUC-Fox-038007	Fusarium oxysporum	54.51	1.00e-166	579.00
IUUC-Fso-038339	Fusarium solani	54.87	0.00e+00	1072.00
IUUC-Gmo-039338	Gadus morhua	84.23	0.00e+00	1783.00
IUUC-Ggr-039823	Gaeumannomyces graminis	54.67	0.00e+00	1125.00
IUUC-Gga-040365	Gallus gallus	48.62	0.00e+00	816.00
IUUC-Gac-041773	Gasterosteus aculeatus	83.94	0.00e+00	1774.00
IUUC-Gma-043198	Glycine max	45.28	0.00e+00	878.00
IUUC-Ggo-045336	Gorilla gorilla	80.74	0.00e+00	1774.00
IUUC-Hsa-045982	Homo sapiens	80.55	0.00e+00	1768.00
IUUC-Hvu-047418	Hordeum vulgare	46.38	0.00e+00	888.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	80.74	0.00e+00	1800.00
IUUC-Kpa-049112	Komagataella pastoris	52.55	0.00e+00	1026.00
IUUC-Lch-050371	Latimeria chalumnae	84.14	0.00e+00	1840.00
IUUC-Lpe-051299	Leersia perrieri	44.52	0.00e+00	886.00
IUUC-Lma-053315	Leptosphaeria maculans	52.69	0.00e+00	1110.00
IUUC-Laf-053948	Loxodonta africana	79.04	0.00e+00	1736.00
IUUC-Mcc-055843	Macaca mulatta	80.74	0.00e+00	1797.00
IUUC-Meu-056258	Macropus eugenii	79.41	0.00e+00	1750.00
IUUC-Mor-057269	Magnaporthe oryzae	54.91	0.00e+00	1106.00
IUUC-Mpo-057435	Magnaporthe poae	55.10	0.00e+00	1107.00
IUUC-Mtr-058572	Medicago truncatula	45.24	0.00e+00	862.00
IUUC-Mla-059176	Melampsora laricipopulina	56.74	0.00e+00	1110.00
IUUC-Mvi-060437	Microbotryum violaceum	55.29	0.00e+00	1093.00
IUUC-Mmr-061405	Microcebus murinus	78.28	0.00e+00	1728.00
IUUC-Mdo-062032	Monodelphis domestica	78.09	0.00e+00	1719.00
IUUC-Mmu-063280	Mus musculus	79.98	0.00e+00	1765.00
IUUC-Mac-065505	Musa acuminata	46.70	0.00e+00	902.00
IUUC-Mpu-066409	Mustela putorius furo	80.64	0.00e+00	1797.00
IUUC-Mlu-067217	Myotis lucifugus	79.98	0.00e+00	1772.00
IUUC-Nfi-068407	Neosartorya fischeri	54.88	0.00e+00	1078.00
IUUC-Ncr-068698	Neurospora crassa	55.47	0.00e+00	1118.00
IUUC-Nle-070072	Nomascus leucogenys	76.70	0.00e+00	1666.00
IUUC-Opr-070715	Ochotona princeps	42.76	0.00e+00	761.00
IUUC-Ont-071671	Oreochromis niloticus	86.81	0.00e+00	1864.00
IUUC-Oan-073306	Ornithorhynchus anatinus	48.37	0.00e+00	729.00
IUUC-Ocu-074544	Oryctolagus cuniculus	80.64	0.00e+00	1796.00
IUUC-Oba-075120	Oryza barthii	45.49	0.00e+00	879.00
IUUC-Obr-076557	Oryza brachyantha	46.09	0.00e+00	867.00
IUUC-Ogl-077887	Oryza glaberrima	45.59	0.00e+00	882.00
IUUC-Ogu-078305	Oryza glumaepatula	44.00	0.00e+00	875.00
IUUC-Oin-079370	Oryza indica	44.46	0.00e+00	861.00
IUUC-Olo-081089	Oryza longistaminata	44.19	0.00e+00	875.00
IUUC-Ome-081942	Oryza meridionalis	45.39	0.00e+00	879.00
IUUC-Oni-082365	Oryza nivara	45.78	0.00e+00	881.00
IUUC-Opu-083301	Oryza punctata	45.11	0.00e+00	884.00
IUUC-Oru-084469	Oryza rufipogon	44.09	0.00e+00	877.00
IUUC-Osa-085949	Oryza sativa	45.59	0.00e+00	887.00
IUUC-Ola-087002	Oryzias latipes	86.04	0.00e+00	1845.00
IUUC-Olu-087687	Ostreococcus lucimarinus	45.82	0.00e+00	837.00
IUUC-Oga-088594	Otolemur garnettii	80.75	0.00e+00	1768.00
IUUC-Oar-090068	Ovis aries	80.28	0.00e+00	1787.00
IUUC-Ptr-090581	Pan troglodytes	44.98	0.00e+00	761.00
IUUC-Pan-092114	Papio anubis	80.83	0.00e+00	1798.00
IUUC-Pma-094214	Petromyzon marinus	64.50	9.00e-57	212.00
IUUC-Pno-095154	Phaeosphaeria nodorum	53.49	0.00e+00	1103.00
IUUC-Ppa-095416	Physcomitrella patens	45.50	0.00e+00	907.00
IUUC-Pfo-097184	Poecilia formosa	85.47	0.00e+00	1837.00
IUUC-Pab-097861	Pongo abelii	80.55	0.00e+00	1759.00
IUUC-Pop-098934	Populus trichocarpa	45.64	0.00e+00	923.00
IUUC-Pca-100347	Procavia capensis	77.64	0.00e+00	1419.00
IUUC-Ppe-102012	Prunus persica	44.75	0.00e+00	895.00
IUUC-Pva-102584	Pteropus vampyrus	80.36	0.00e+00	1812.00
IUUC-Pgr-103336	Puccinia graminis	55.76	0.00e+00	1085.00
IUUC-Ptt-103939	Puccinia triticina	54.78	0.00e+00	1078.00
IUUC-Pte-104200	Pyrenophora teres	54.37	0.00e+00	1104.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	53.44	0.00e+00	1095.00
IUUC-Rno-105462	Rattus norvegicus	80.26	0.00e+00	1758.00
IUUC-Sce-106245	Saccharomyces cerevisiae	51.86	0.00e+00	1058.00
IUUC-Sha-107142	Sarcophilus harrisii	79.89	0.00e+00	1771.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	55.26	0.00e+00	1132.00
IUUC-Spo-108034	Schizosaccharomyces pombe	55.41	0.00e+00	1095.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	56.27	0.00e+00	1083.00
IUUC-Smo-108912	Selaginella moellendorffii	46.74	0.00e+00	893.00
IUUC-Sit-110281	Setaria italica	45.72	0.00e+00	902.00
IUUC-Sly-110914	Solanum lycopersicum	45.92	0.00e+00	915.00
IUUC-Stu-112109	Solanum tuberosum	45.63	0.00e+00	915.00
IUUC-Sar-113737	Sorex araneus	79.79	0.00e+00	1766.00
IUUC-Sbi-114089	Sorghum bicolor	46.02	0.00e+00	906.00
IUUC-Sre-115148	Sporisorium reilianum	55.76	0.00e+00	1095.00
IUUC-Ssc-115777	Sus scrofa	80.66	0.00e+00	1789.00
IUUC-Tru-118742	Takifugu rubripes	86.33	0.00e+00	1796.00
IUUC-Tni-120401	Tetraodon nigroviridis	86.33	0.00e+00	1799.00
IUUC-Tca-121672	Theobroma cacao	45.35	0.00e+00	907.00
IUUC-Tre-122009	Trichoderma reesei	54.15	0.00e+00	1055.00
IUUC-Tvi-122259	Trichoderma virens	54.88	0.00e+00	1045.00
IUUC-Tae-125113	Triticum aestivum	46.87	0.00e+00	872.00
IUUC-Tur-126189	Triticum urartu	46.51	0.00e+00	868.00
IUUC-Tme-127055	Tuber melanosporum	53.18	0.00e+00	1006.00
IUUC-Tbe-127487	Tupaia belangeri	77.09	0.00e+00	866.00
IUUC-Ttr-128331	Tursiops truncatus	80.08	0.00e+00	1769.00
IUUC-Uma-129387	Ustilago maydis	55.98	0.00e+00	1101.00
IUUC-Vda-129977	Verticillium dahliae	54.38	0.00e+00	1028.00
IUUC-Vvi-130857	Vitis vinifera	45.60	0.00e+00	908.00
IUUC-Xtr-132026	Xenopus tropicalis	66.15	0.00e+00	1303.00
IUUC-Xma-133805	Xiphophorus maculatus	85.76	0.00e+00	1818.00
IUUC-Yli-134547	Yarrowia lipolytica	53.59	0.00e+00	1098.00
IUUC-Zma-135052	Zea mays	46.04	0.00e+00	905.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence