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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Ath-007638
Ensembl Protein ID AT2G46500.2
UniProt Accession Q9ZPY9; B9DGU3; B9DHV3; P4KG4_ARATH
Genbank Protein ID AAD20161.1; AAM15268.1; AEC10708.1; AEC10709.1; AAL31898.1; AAO11610.1; BAH19960.1; BAH20320.1
Protein Name Phosphatidylinositol 4-kinase gamma 4; Ubiquitin-like domain kinase gamma 4
Genbank Nucleotide ID AC006418; AC006526; CP002685; CP002685; AF419566; BT002694; AK317284; AK317659
Gene Name PI4KG4; PI4KGAMMA4; UBDKGAMMA4; At2g46500; F11C10.19; F13A10.3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT2G46500 AT2G46500.3 AT2G46500.3
AT2G46500 AT2G46500.2 AT2G46500.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
Protein-protein Interaction
iRefIndexMentha
Protein Expression/Proteomics
Status Reviewed
Details
Family Domain References (PMIDs)
ULD/UDP/UFD/MUB MUB 17880284; 25320573
Classification
Family E-value Score Start End
ULD/UDP/UBQ/UBQ_PIM 9.70e-36 122.4 113 187
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UBQ/UBQ_PIM

   S: 3    ltvktlkgkefelevseddtveelKekiakesg..vppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
    l vkt++gk+++++v++ +++ +K++i+k++g v+p++q+++y+G++L+D++ +++++ +d+sv+hl+v++s
   Q: 113 LDVKTTCGKHCRFHVERGRNIGYVKKQISKKRGdfVDPDEQEILYEGEKLEDQSLINDICRNDDSVLHLLVRRSA 187
    78**********************************************************************985 PP
   

Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description



     The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3) (By similarity). Undergoes autophosphorylation and phosphorylates serine/threonine residues of protein substrates. Phosphorylates RPN10 and UFD1 in vitro.
The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3) (By similarity). Undergoes autophosphorylation and phosphorylates serine/threonine residues of protein substrates. Phosphorylates RPN10 and UFD1 in vitro.
Protein Sequence
(Fasta)
MSSAGVALSP VRSEPLIMPL VRANSCLDSY PDDTIMIYLT LPGSVIPMRV LESDSIESVK 60
LRIQSYRGFV VRNQKLVFGG RELARSNSNM RDYGVSEGNI LHLVLKLSDL QVLDVKTTCG 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Ath-007638|ULD,MUB;ULD,UBQ_PIM|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAACGGTGA AATAATGACG ATTAAAACCC CAAAGTCTCT GGCTTGGTTT CCACTCCAAG 60
GGTAAAATAC AAAACAAAAT CAACGAAACT GCCGTACACC GTTGACAATA AACAAAGGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ath-007638|ULD,MUB;ULD,UBQ_PIM|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000403--PI3/4_kinase_cat_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF00454--PI3_PI4_kinase
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0004430--F:1-phosphatidylinositol 4-kinase activity
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0046854--P:phosphatidylinositol phosphorylation
GO:0046777--P:protein autophosphorylation
GO:0009651--P:response to salt stress

KEGG ath:AT2G46500
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001119 Aegilops tauschii 54.53 2.00e-173 601.00
IUUC-Atr-003173 Amborella trichopoda 60.72 0.00e+00 715.00
IUUC-Aly-006373 Arabidopsis lyrata 97.17 0.00e+00 1110.00
IUUC-Bdi-014830 Brachypodium distachyon 54.48 2.00e-177 615.00
IUUC-Bol-015291 Brassica oleracea 84.71 0.00e+00 957.00
IUUC-Hvu-047637 Hordeum vulgare 54.88 9.00e-177 612.00
IUUC-Lpe-051347 Leersia perrieri 54.29 2.00e-176 611.00
IUUC-Mtr-058430 Medicago truncatula 58.32 0.00e+00 684.00
IUUC-Mac-064878 Musa acuminata 52.90 5.00e-165 573.00
IUUC-Oba-075122 Oryza barthii 58.07 0.00e+00 635.00
IUUC-Obr-076735 Oryza brachyantha 57.90 2.00e-179 621.00
IUUC-Ogl-077728 Oryza glaberrima 58.07 0.00e+00 635.00
IUUC-Ogu-078710 Oryza glumaepatula 58.07 0.00e+00 633.00
IUUC-Oin-079877 Oryza indica 58.07 0.00e+00 633.00
IUUC-Olo-080554 Oryza longistaminata 54.80 2.00e-179 621.00
IUUC-Ome-081224 Oryza meridionalis 58.07 0.00e+00 632.00
IUUC-Oni-082355 Oryza nivara 58.07 0.00e+00 632.00
IUUC-Opu-083124 Oryza punctata 54.75 6.00e-180 623.00
IUUC-Oru-085036 Oryza rufipogon 58.07 0.00e+00 633.00
IUUC-Osa-085868 Oryza sativa 58.07 0.00e+00 633.00
IUUC-Olu-087862 Ostreococcus lucimarinus 47.89 7.00e-68 249.00
IUUC-Ppa-095406 Physcomitrella patens 47.93 2.00e-149 521.00
IUUC-Pop-098893 Populus trichocarpa 64.70 0.00e+00 784.00
IUUC-Smo-109415 Selaginella moellendorffii 49.43 2.00e-145 508.00
IUUC-Sit-109885 Setaria italica 58.03 0.00e+00 642.00
IUUC-Sly-110868 Solanum lycopersicum 65.79 0.00e+00 773.00
IUUC-Stu-112829 Solanum tuberosum 65.45 0.00e+00 769.00
IUUC-Sbi-114169 Sorghum bicolor 57.27 0.00e+00 632.00
IUUC-Tca-121450 Theobroma cacao 65.66 0.00e+00 783.00
IUUC-Tae-123343 Triticum aestivum 54.53 6.00e-173 600.00
Created Date 25-Jun-2017

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