iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067968

Ensembl Protein ID

ENSMLUP00000012975.2

UniProt Accession

G1PPM6; G1PPM6_MYOLU

Genbank Protein ID

ENSMLUP00000012975

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AAPE02031544

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000014258.2	ENSMLUT00000014264.2	ENSMLUP00000012975.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	46.78	2.00e-115	412.00	IUUC-Ath-007014

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

FSSFVVGEHQ LTGHKVAVKI LNRQKIRSLD VVGKIKREIQ NLKLFRHPHI IKLKRYQVIS 60
TPTDFFMVME YVSGGELFDY ICKHGRVEEM EARRLFQQIL SAVDYCHRHM VVHRDLKPEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTCTTCAT TTGTAGTTGG AGAACATCAG TTGACAGGTC ATAAAGTGGC AGTTAAAATC 60
CTAAATAGAC AGAAGATTCG CAGTTTAGAT GTTGTTGGAA AAATAAAGCG GGAAATTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	45.77	8.00e-115	407.00
IUUC-Apl-003395	Anas platyrhynchos	91.59	0.00e+00	994.00
IUUC-Aca-004480	Anolis carolinensis	93.39	0.00e+00	943.00
IUUC-Aly-006289	Arabidopsis lyrata	46.67	8.00e-117	414.00
IUUC-Ath-007014	Arabidopsis thaliana	46.78	6.00e-117	414.00
IUUC-Ame-011019	Astyanax mexicanus	84.73	0.00e+00	943.00
IUUC-Bgr-012045	Blumeria graminis	60.63	4.00e-94	338.00
IUUC-Bci-013774	Botrytis cinerea	45.89	2.00e-96	346.00
IUUC-Bdi-014319	Brachypodium distachyon	46.06	4.00e-116	411.00
IUUC-Bol-016242	Brassica oleracea	47.06	3.00e-119	422.00
IUUC-Bra-016750	Brassica rapa	46.95	1.00e-119	423.00
IUUC-Cel-018518	Caenorhabditis elegans	57.59	9.00e-168	583.00
IUUC-Cja-019386	Callithrix jacchus	96.97	0.00e+00	1029.00
IUUC-Cpo-021805	Cavia porcellus	96.78	0.00e+00	1027.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	53.72	1.00e-87	316.00
IUUC-Csa-024267	Chlorocebus sabaeus	96.97	0.00e+00	1016.00
IUUC-Cin-025550	Ciona intestinalis	60.04	0.00e+00	629.00
IUUC-Csv-026139	Ciona savignyi	58.27	0.00e+00	626.00
IUUC-Cne-027044	Cryptococcus neoformans	50.00	6.00e-99	355.00
IUUC-Dor-030578	Dipodomys ordii	96.21	0.00e+00	1023.00
IUUC-Dme-031704	Drosophila melanogaster	58.54	0.00e+00	636.00
IUUC-Eca-034016	Equus caballus	97.32	0.00e+00	1020.00
IUUC-Fox-038073	Fusarium oxysporum	51.60	1.00e-97	350.00
IUUC-Fso-038236	Fusarium solani	50.58	4.00e-94	339.00
IUUC-Gga-040546	Gallus gallus	90.91	0.00e+00	990.00
IUUC-Gac-041822	Gasterosteus aculeatus	83.08	0.00e+00	889.00
IUUC-Ggo-045303	Gorilla gorilla	97.16	0.00e+00	1031.00
IUUC-Hsa-045746	Homo sapiens	97.16	0.00e+00	1031.00
IUUC-Hvu-047406	Hordeum vulgare	45.86	2.00e-116	412.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	96.97	0.00e+00	1029.00
IUUC-Kpa-049190	Komagataella pastoris	44.19	1.00e-112	400.00
IUUC-Loc-052928	Lepisosteus oculatus	89.22	0.00e+00	966.00
IUUC-Laf-053459	Loxodonta africana	96.40	0.00e+00	1027.00
IUUC-Mcc-055862	Macaca mulatta	97.16	0.00e+00	1031.00
IUUC-Mga-059206	Meleagris gallopavo	91.40	0.00e+00	988.00
IUUC-Mvi-060337	Microbotryum violaceum	40.83	4.00e-100	358.00
IUUC-Mmr-061619	Microcebus murinus	96.40	0.00e+00	1014.00
IUUC-Mdo-062160	Monodelphis domestica	91.48	0.00e+00	994.00
IUUC-Mmu-063406	Mus musculus	95.08	0.00e+00	1007.00
IUUC-Mac-064518	Musa acuminata	44.22	6.00e-112	397.00
IUUC-Mpu-066326	Mustela putorius furo	97.71	0.00e+00	1028.00
IUUC-Ncr-068665	Neurospora crassa	39.84	2.00e-98	353.00
IUUC-Nle-070158	Nomascus leucogenys	96.97	0.00e+00	1030.00
IUUC-Ont-071395	Oreochromis niloticus	85.71	0.00e+00	933.00
IUUC-Ogl-077718	Oryza glaberrima	48.74	2.00e-114	405.00
IUUC-Oin-079889	Oryza indica	44.79	5.00e-115	407.00
IUUC-Ola-087169	Oryzias latipes	83.46	0.00e+00	909.00
IUUC-Ptr-090741	Pan troglodytes	97.16	0.00e+00	1031.00
IUUC-Ppa-095615	Physcomitrella patens	49.43	5.00e-115	407.00
IUUC-Pfo-096295	Poecilia formosa	84.77	0.00e+00	922.00
IUUC-Pab-098023	Pongo abelii	97.16	0.00e+00	1031.00
IUUC-Pop-100042	Populus trichocarpa	46.68	6.00e-119	421.00
IUUC-Ppe-101642	Prunus persica	47.42	3.00e-116	412.00
IUUC-Pva-102470	Pteropus vampyrus	96.40	0.00e+00	1019.00
IUUC-Ptt-103713	Puccinia triticina	38.61	5.00e-75	275.00
IUUC-Rno-104960	Rattus norvegicus	96.02	0.00e+00	1021.00
IUUC-Sce-106290	Saccharomyces cerevisiae	41.54	4.00e-108	385.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	45.37	4.00e-95	342.00
IUUC-Sly-110890	Solanum lycopersicum	46.38	4.00e-117	414.00
IUUC-Stu-112144	Solanum tuberosum	44.91	4.00e-111	395.00
IUUC-Sre-115141	Sporisorium reilianum	65.50	6.00e-105	375.00
IUUC-Tru-118735	Takifugu rubripes	84.02	0.00e+00	919.00
IUUC-Tsy-119503	Tarsius syrichta	94.25	0.00e+00	969.00
IUUC-Tni-119880	Tetraodon nigroviridis	84.25	0.00e+00	919.00
IUUC-Tca-121386	Theobroma cacao	45.96	7.00e-118	417.00
IUUC-Tae-123515	Triticum aestivum	46.43	2.00e-117	416.00
IUUC-Tur-126416	Triticum urartu	45.77	9.00e-115	407.00
IUUC-Tbe-127791	Tupaia belangeri	85.34	3.00e-112	398.00
IUUC-Uma-129372	Ustilago maydis	65.50	3.00e-104	372.00
IUUC-Vpa-130220	Vicugna pacos	97.32	0.00e+00	1018.00
IUUC-Xtr-132954	Xenopus tropicalis	92.35	0.00e+00	996.00
IUUC-Xma-134119	Xiphophorus maculatus	84.59	0.00e+00	920.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence