iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d005085	Zm00001d005085_T015	Zm00001d005085_T015
Zm00001d005085	Zm00001d005085_T010	Zm00001d005085_T010
Zm00001d005085	Zm00001d005085_T007	Zm00001d005085_T007
Zm00001d005085	Zm00001d005085_T002	Zm00001d005085_T002
Zm00001d005085	Zm00001d005085_T020	Zm00001d005085_T020
Zm00001d005085	Zm00001d005085_T019	Zm00001d005085_T019
Zm00001d005085	Zm00001d005085_T012	Zm00001d005085_T012

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.40e-166	556.8	446	941

Active Site

Position(s)	Description	Evidence
627	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkeln 85
           YD Qi ++G++ q+kl+++k+++vG g+lGcE+lKnL+l+G+     g++tv+D+d +e+snl+rqFLfr++++g++K+ vaa a+  +n
   Q: 446  YDAQISVFGAKLQKKLEQSKIFMVGSGALGCEFLKNLALMGIscsqnGKLTVTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMAIN 535
           ****************************************************************************************** PP
   S: 86   pdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiP 172
           p+ +vea +++ ++++e+++   F + +d Vv+aldn+ ar++++++c++ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P
   Q: 536  PKLHVEALQNRASPETENVFndaFWESLDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAP 625
           ******************9999******************************************************************** PP
   S: 173  fctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkaf..... 245
           +ct+ ++p +++h+++wa              +n +l++  g  + +     ++ ++ +++v + l++ + e+f+++i++a+ +f     
   Q: 626  MCTVHSFPHNIDHCLTWArsefegllektpTEVNAFLSNPGGYATAARTAGDAQARDQLERVIECLETDKCETFQDCITWARLNFllmvy 715
           *****************************999999999999999999999999****************************987533333 PP
   S: 246  ...akttinsikqllksfecdivtkskspfwv.......................................................... 274
              + +++n +kql+  f+ d +t+s++pfw+                                                          
   Q: 716  irfEDYFSNRVKQLTFTFPEDAMTSSGAPFWSapkrfprplefsssdsshlnfllaasvlraetfgihipdwaknpkklaeavdkvivpd 805
           3227888888************************************************************99998886666666665554 PP
   S: 275  sfcsnaealqvpekvekdeevvkasap.lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlik 359
             +++  +++++ek+++   ++ ++a+ ++ l+++le+  k+  +   ++ ++fekddd   ++dl++ +an+ra +++i++ +d+ + k
   Q: 806  FQPKQGVKIETDEKATSLSSASVDDAAvIEELIAKLEEIFKTlpPRFHMNPIQFEKDDDTnfHMDLIAGFANMRARNYSIPE-VDKLKAK 894
           4444444555555555555554444449999999999866543345568899******************************.******* PP
   S: 360  eiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
            iag+iipaiat +a+  Gl+++E++Kv+ g  k e ++n+f ++a+
   Q: 895  FIAGRIIPAIATSTAMATGLVCLELYKVLAGghKVEDYRNTFANLAI 941
           *******************************999********99876 PP

Organism

Zea mays

Protein Sequence
(Fasta)

MLPRKRGVDA GEDQDLHNKA LRAAAVAQDK EKVVAEMGGR APEIDEDLHS RQLAVYGRET 60
MKRLFGSNVL ISGLQGLGAE IAKNLVLAGV KSVTLHDDGK VELWDLSSNF FLSEKDVGQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACTAACCCT ATTAGGCCAG ACCAGAGCTG AAGCAGAGCG GAGAGGTCTG CTCGCCGGCC 60
ATCGAATCCA GGCTCCTCCA AGGTGATCTC TCTCGATCGC TTCCGGCCTC ACCGTAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	89.94	0.00e+00	1869.00
IUUC-Atr-002684	Amborella trichopoda	77.37	0.00e+00	1667.00
IUUC-Aly-005515	Arabidopsis lyrata	78.05	0.00e+00	1690.00
IUUC-Bdi-014843	Brachypodium distachyon	89.53	0.00e+00	1839.00
IUUC-Bol-015665	Brassica oleracea	78.74	0.00e+00	1670.00
IUUC-Cho-024682	Choloepus hoffmanni	36.72	8.00e-102	364.00
IUUC-Gma-043165	Glycine max	81.34	0.00e+00	1728.00
IUUC-Hvu-047418	Hordeum vulgare	89.25	0.00e+00	1862.00
IUUC-Mtr-058572	Medicago truncatula	80.18	0.00e+00	1662.00
IUUC-Ppe-102012	Prunus persica	79.13	0.00e+00	1707.00
IUUC-Smo-109211	Selaginella moellendorffii	70.16	0.00e+00	1536.00
IUUC-Tca-121436	Theobroma cacao	78.90	0.00e+00	1690.00
IUUC-Tae-125113	Triticum aestivum	88.77	0.00e+00	1815.00
IUUC-Tur-126330	Triticum urartu	90.04	0.00e+00	1873.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence