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Tag Content
UUCD2 ID IUUC-Cin-025681
UUCD1 version UUC-CiI-00521
Ensembl Protein ID ENSCINP00000012742.3
UniProt Accession F7BKT8; F7BKT8_CIOIN
Protein Name Coatomer subunit beta'
Gene Name LOC100178403
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCING00000006169.3 ENSCINT00000012742.3 ENSCINP00000012742.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 9.90e-32 107.5 227 257
UBD/Beta-Prp 1.10e-69 234.7 13 297
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+  + c++f ++ +++ +Gs Dgt+k+W 
   Q: 227  GHSQNIVCVSFhPElPIIMTGSEDGTVKIWH 257
           8***********999***************5 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           +++++++cv+ +p++++++++ ++g + +w+ +t+ l++s++ ++ +v+a++f p++++ +tgs+D+ i+v++++t +  h++++h+d+
   Q: 13   ARSDRVKCVDLHPSEPWMLVSLYNGNVHIWNHETQLLVKSFEVCDLPVRATRFVPRKNWVITGSDDMQIRVFNYNTLERSHAFEAHTDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           ++s++++p++ ++++ s+d  i++wd+++++   ++++gh++ v+ +v++p++ n ++s+slD  +++W+l +++   tltg h++ v+
   Q: 102  IRSIAVHPTQPYILTSSDDMLIKLWDWDKKWSCAQVFEGHTHYVMQIVINPKDnNQFASASLDCSIKVWQLGSATPNFTLTG-HDKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++   g  ++l+sg++d+  k+wd+q+++cv+tl+gh++n+ +v f+p+  ++++gs+Dg+++iW   +  l +tl++  ++v++++
   Q: 190  CVDYYNGGdkPYLISGADDRLTKIWDYQNKTCVQTLEGHSQNIVCVSFHPELPIIMTGSEDGTVKIWHANTYRLETTLNYGMERVWCIS 278
           ***8887778******************************************************************************* PP
   S: 272  vlsfgdnvlvlgsedskvni 291
           ++  g n+++lg ++++++i
   Q: 279  AM-KGSNNIALGYDEGSIMI 297
           *4.44666666666666665 PP
   
Organism Ciona intestinalis
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
QPLRLDIKRK LNARSDRVKC VDLHPSEPWM LVSLYNGNVH IWNHETQLLV KSFEVCDLPV 60
RATRFVPRKN WVITGSDDMQ IRVFNYNTLE RSHAFEAHTD YIRSIAVHPT QPYILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cin-025681|E3,WD_repeat;UBD,Beta-Prp|Ciona intestinalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGCCTCTGC GCTTGGATAT CAAGCGAAAA CTTAACGCAA GATCGGATCG TGTAAAATGT 60
GTTGATTTAC ATCCTAGTGA ACCATGGATG TTGGTATCAC TTTATAATGG TAAGATTTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cin-025681|E3,WD_repeat;UBD,Beta-Prp|Ciona intestinalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 51.32 0.00e+00 893.00
IUUC-Aml-002154 Ailuropoda melanoleuca 72.32 0.00e+00 1432.00
IUUC-Atr-003090 Amborella trichopoda 57.70 0.00e+00 1011.00
IUUC-Apl-003976 Anas platyrhynchos 77.12 0.00e+00 1446.00
IUUC-Aca-004301 Anolis carolinensis 78.16 0.00e+00 1444.00
IUUC-Aly-005643 Arabidopsis lyrata 58.77 0.00e+00 1028.00
IUUC-Ath-007630 Arabidopsis thaliana 59.24 0.00e+00 1043.00
IUUC-Ago-007914 Ashbya gossypii 46.01 0.00e+00 740.00
IUUC-Acl-008237 Aspergillus clavatus 52.91 0.00e+00 926.00
IUUC-Afl-008535 Aspergillus flavus 51.10 0.00e+00 873.00
IUUC-Afu-008845 Aspergillus fumigatus 51.28 0.00e+00 903.00
IUUC-Ani-009135 Aspergillus nidulans 52.83 0.00e+00 889.00
IUUC-Ang-009654 Aspergillus niger 54.59 0.00e+00 821.00
IUUC-Aor-009939 Aspergillus oryzae 51.52 0.00e+00 928.00
IUUC-Ate-010355 Aspergillus terreus 52.68 0.00e+00 882.00
IUUC-Ame-010922 Astyanax mexicanus 70.30 0.00e+00 1272.00
IUUC-Bgr-012249 Blumeria graminis 54.22 0.00e+00 913.00
IUUC-Bta-013579 Bos taurus 79.55 0.00e+00 1248.00
IUUC-Bci-013866 Botrytis cinerea 54.49 0.00e+00 898.00
IUUC-Bdi-015046 Brachypodium distachyon 58.33 0.00e+00 1043.00
IUUC-Bol-015466 Brassica oleracea 57.99 0.00e+00 1025.00
IUUC-Bra-016617 Brassica rapa 57.93 0.00e+00 1025.00
IUUC-Cel-018387 Caenorhabditis elegans 65.40 0.00e+00 1182.00
IUUC-Cja-019145 Callithrix jacchus 75.54 0.00e+00 1435.00
IUUC-Cfa-020564 Canis familiaris 75.54 0.00e+00 1433.00
IUUC-Cpo-022201 Cavia porcellus 75.43 0.00e+00 1431.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 59.15 0.00e+00 982.00
IUUC-Csa-023383 Chlorocebus sabaeus 80.25 0.00e+00 1006.00
IUUC-Cho-024454 Choloepus hoffmanni 74.59 0.00e+00 1186.00
IUUC-Csv-026012 Ciona savignyi 88.36 0.00e+00 1617.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 50.55 0.00e+00 810.00
IUUC-Cne-026986 Cryptococcus neoformans 49.88 0.00e+00 874.00
IUUC-Cme-027219 Cyanidioschyzon merolae 46.93 0.00e+00 834.00
IUUC-Dre-027846 Danio rerio 74.78 0.00e+00 1448.00
IUUC-Dor-030462 Dipodomys ordii 75.19 0.00e+00 1073.00
IUUC-Dse-031268 Dothistroma septosporum 52.94 0.00e+00 919.00
IUUC-Dme-031791 Drosophila melanogaster 66.16 0.00e+00 1215.00
IUUC-Ete-033166 Echinops telfairi 71.15 0.00e+00 855.00
IUUC-Eca-034180 Equus caballus 74.11 0.00e+00 1383.00
IUUC-Eeu-035086 Erinaceus europaeus 58.27 0.00e+00 644.00
IUUC-Fca-036265 Felis catus 75.92 0.00e+00 1428.00
IUUC-Fal-037202 Ficedula albicollis 76.22 0.00e+00 1392.00
IUUC-Fox-037711 Fusarium oxysporum 54.37 0.00e+00 855.00
IUUC-Fso-038268 Fusarium solani 54.04 0.00e+00 852.00
IUUC-Gmo-039046 Gadus morhua 78.44 0.00e+00 1436.00
IUUC-Ggr-039863 Gaeumannomyces graminis 53.94 0.00e+00 880.00
IUUC-Gga-041112 Gallus gallus 77.00 0.00e+00 1444.00
IUUC-Gac-041733 Gasterosteus aculeatus 77.84 0.00e+00 1387.00
IUUC-Gma-042910 Glycine max 59.44 0.00e+00 1048.00
IUUC-Ggo-044984 Gorilla gorilla 75.81 0.00e+00 1429.00
IUUC-Hsa-046698 Homo sapiens 75.69 0.00e+00 1429.00
IUUC-Hvu-047669 Hordeum vulgare 67.04 5.00e-158 548.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 77.67 0.00e+00 1427.00
IUUC-Kpa-049265 Komagataella pastoris 49.50 0.00e+00 849.00
IUUC-Lch-050473 Latimeria chalumnae 73.69 0.00e+00 1457.00
IUUC-Lpe-051579 Leersia perrieri 57.80 0.00e+00 1033.00
IUUC-Loc-052675 Lepisosteus oculatus 76.59 0.00e+00 1442.00
IUUC-Lma-053218 Leptosphaeria maculans 52.67 0.00e+00 905.00
IUUC-Laf-053757 Loxodonta africana 75.98 0.00e+00 1422.00
IUUC-Mcc-054859 Macaca mulatta 75.54 0.00e+00 1434.00
IUUC-Meu-056174 Macropus eugenii 70.56 3.00e-163 567.00
IUUC-Mor-057264 Magnaporthe oryzae 53.87 0.00e+00 858.00
IUUC-Mpo-057538 Magnaporthe poae 54.19 0.00e+00 892.00
IUUC-Mtr-058310 Medicago truncatula 59.08 0.00e+00 1047.00
IUUC-Mla-058937 Melampsora laricipopulina 51.82 0.00e+00 875.00
IUUC-Mga-059875 Meleagris gallopavo 76.71 0.00e+00 1437.00
IUUC-Mvi-060240 Microbotryum violaceum 50.87 0.00e+00 875.00
IUUC-Mmr-061261 Microcebus murinus 76.04 0.00e+00 1432.00
IUUC-Mdo-062076 Monodelphis domestica 76.77 0.00e+00 1442.00
IUUC-Mmu-063324 Mus musculus 76.15 0.00e+00 1430.00
IUUC-Mac-064636 Musa acuminata 59.22 0.00e+00 1023.00
IUUC-Mpu-065961 Mustela putorius furo 75.92 0.00e+00 1427.00
IUUC-Mlu-067059 Myotis lucifugus 75.09 0.00e+00 1392.00
IUUC-Nfi-068277 Neosartorya fischeri 52.51 0.00e+00 892.00
IUUC-Ncr-068659 Neurospora crassa 52.52 0.00e+00 897.00
IUUC-Nle-069034 Nomascus leucogenys 75.54 0.00e+00 1433.00
IUUC-Opr-070334 Ochotona princeps 79.48 0.00e+00 1285.00
IUUC-Ont-071563 Oreochromis niloticus 78.32 0.00e+00 1435.00
IUUC-Oan-073416 Ornithorhynchus anatinus 77.67 0.00e+00 1371.00
IUUC-Ocu-074522 Oryctolagus cuniculus 75.43 0.00e+00 1427.00
IUUC-Oba-075760 Oryza barthii 58.23 0.00e+00 1017.00
IUUC-Obr-076163 Oryza brachyantha 60.29 0.00e+00 1042.00
IUUC-Ogl-077450 Oryza glaberrima 59.20 0.00e+00 1041.00
IUUC-Ogu-078994 Oryza glumaepatula 58.23 0.00e+00 1015.00
IUUC-Oin-079856 Oryza indica 55.77 0.00e+00 1015.00
IUUC-Olo-080731 Oryza longistaminata 57.38 0.00e+00 998.00
IUUC-Ome-081762 Oryza meridionalis 54.66 0.00e+00 937.00
IUUC-Oni-082324 Oryza nivara 58.23 0.00e+00 1015.00
IUUC-Opu-083400 Oryza punctata 54.07 0.00e+00 1004.00
IUUC-Oru-084829 Oryza rufipogon 58.23 0.00e+00 1016.00
IUUC-Osa-086026 Oryza sativa 59.20 0.00e+00 1045.00
IUUC-Ola-087245 Oryzias latipes 73.80 0.00e+00 1432.00
IUUC-Olu-087655 Ostreococcus lucimarinus 57.74 0.00e+00 1014.00
IUUC-Oga-088163 Otolemur garnettii 73.32 0.00e+00 1376.00
IUUC-Oar-089842 Ovis aries 75.54 0.00e+00 1435.00
IUUC-Ptr-090501 Pan troglodytes 75.54 0.00e+00 1432.00
IUUC-Pan-092011 Papio anubis 75.54 0.00e+00 1436.00
IUUC-Psi-093308 Pelodiscus sinensis 78.17 0.00e+00 1439.00
IUUC-Pma-094695 Petromyzon marinus 70.75 0.00e+00 1263.00
IUUC-Pno-094785 Phaeosphaeria nodorum 59.17 5.00e-108 383.00
IUUC-Ppa-095911 Physcomitrella patens 60.41 0.00e+00 1073.00
IUUC-Pfo-096587 Poecilia formosa 74.92 0.00e+00 1436.00
IUUC-Pab-097926 Pongo abelii 74.00 0.00e+00 1346.00
IUUC-Pop-099634 Populus trichocarpa 59.42 0.00e+00 1043.00
IUUC-Pca-100965 Procavia capensis 75.00 0.00e+00 1397.00
IUUC-Ppe-101470 Prunus persica 60.25 0.00e+00 1047.00
IUUC-Pva-102451 Pteropus vampyrus 74.14 0.00e+00 1066.00
IUUC-Pgr-103453 Puccinia graminis 52.21 0.00e+00 904.00
IUUC-Ptt-103868 Puccinia triticina 51.97 0.00e+00 897.00
IUUC-Pte-104274 Pyrenophora teres 53.37 0.00e+00 926.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 52.84 0.00e+00 879.00
IUUC-Rno-105979 Rattus norvegicus 68.16 0.00e+00 1065.00
IUUC-Sce-106269 Saccharomyces cerevisiae 46.98 0.00e+00 764.00
IUUC-Sha-106905 Sarcophilus harrisii 77.94 0.00e+00 1441.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 46.52 0.00e+00 805.00
IUUC-Spo-108299 Schizosaccharomyces pombe 47.16 0.00e+00 820.00
IUUC-Smo-108695 Selaginella moellendorffii 59.43 0.00e+00 1036.00
IUUC-Sit-110692 Setaria italica 59.90 0.00e+00 1032.00
IUUC-Sly-111775 Solanum lycopersicum 59.50 0.00e+00 1035.00
IUUC-Stu-112906 Solanum tuberosum 59.10 0.00e+00 941.00
IUUC-Sar-113472 Sorex araneus 73.30 0.00e+00 978.00
IUUC-Sbi-114052 Sorghum bicolor 61.25 0.00e+00 1062.00
IUUC-Sre-115040 Sporisorium reilianum 49.88 0.00e+00 877.00
IUUC-Ssc-115593 Sus scrofa 75.31 0.00e+00 1430.00
IUUC-Tgu-117239 Taeniopygia guttata 76.20 0.00e+00 1447.00
IUUC-Tru-118025 Takifugu rubripes 76.56 0.00e+00 1430.00
IUUC-Tsy-118824 Tarsius syrichta 73.57 0.00e+00 989.00
IUUC-Tni-120142 Tetraodon nigroviridis 77.75 0.00e+00 1425.00
IUUC-Tca-121613 Theobroma cacao 59.54 0.00e+00 1048.00
IUUC-Tre-122072 Trichoderma reesei 53.45 0.00e+00 896.00
IUUC-Tvi-122546 Trichoderma virens 53.65 0.00e+00 885.00
IUUC-Tae-125395 Triticum aestivum 59.20 0.00e+00 1041.00
IUUC-Tur-126283 Triticum urartu 52.50 0.00e+00 890.00
IUUC-Tme-127041 Tuber melanosporum 55.97 0.00e+00 959.00
IUUC-Tbe-127770 Tupaia belangeri 75.64 0.00e+00 1083.00
IUUC-Ttr-129294 Tursiops truncatus 75.81 0.00e+00 1428.00
IUUC-Uma-129351 Ustilago maydis 49.39 0.00e+00 870.00
IUUC-Vda-129716 Verticillium dahliae 53.26 0.00e+00 916.00
IUUC-Vpa-130037 Vicugna pacos 68.05 0.00e+00 676.00
IUUC-Vvi-131689 Vitis vinifera 60.02 0.00e+00 1046.00
IUUC-Xtr-132633 Xenopus tropicalis 76.36 0.00e+00 1431.00
IUUC-Xma-133347 Xiphophorus maculatus 72.42 0.00e+00 1438.00
IUUC-Yli-134455 Yarrowia lipolytica 50.51 0.00e+00 839.00
IUUC-Zma-135867 Zea mays 57.41 0.00e+00 1046.00
Created Date 25-Jun-2017

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