iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125488

Ensembl Protein ID

TRIAE_CS42_7DS_TGACv1_623122_AA2049790.1

UniProt Accession

A0A1D6D2R5; A0A1D6D2R5_WHEAT

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_7DS_TGACv1_623122_AA2049790	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.2	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.2
TRIAE_CS42_7DS_TGACv1_623122_AA2049790	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.1	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.1
TRIAE_CS42_7DS_TGACv1_623122_AA2049790	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.3	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.3
TRIAE_CS42_7DS_TGACv1_623122_AA2049790	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.4	TRIAE_CS42_7DS_TGACv1_623122_AA2049790.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-32	111.2	183	224
UBD/Beta-Prp	1.30e-66	227.5	10	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 183  GHQKGVNCVDYftgGDrPYLITGSDDSTAKVWDYQTKSCVQT 224
           8********966*9778*******************999986 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD 73
            ++++++++++v+ +p +++++++ ++gt+ +wd++t+++++s++  e +v++ kf +++++ v g++D
   Q: 10   KFAQRSERVKSVDLHPTEPWILASLYSGTLCIWDYQTQTMVKSFEVSELPVRSAKFVSRKQWVVAGADD 78
           567788999************************************************************ PP
   S: 74   rtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvnc 142
           ++i+v++++t + + ++++h+d++++++++p+  +++s s+d  i++wd+++g+   ++++gh++ v+ 
   Q: 79   MFIRVYNYNTMDKIKVFEAHTDYIRCVAVHPTLPYVLSSSDDMLIKLWDWDKGWMCTQIFEGHSHYVMQ 147
           ******************************************************9999*********** PP
   S: 143  vvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwd 208
           v+++p++ n ++s+slDrt ++W+l + +   tl g h++ v++++     ++++l++gs+d+t k+wd
   Q: 148  VTFNPKDtNTFASASLDRTTKIWSLGSPDPNFTLDG-HQKGVNCVDyfTGGDRPYLITGSDDSTAKVWD 215
           ***********************************9.*********7445566**************** PP
   S: 209  lqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
           +qt++cv+tl+ght n++ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v++v +++   
   Q: 216  YQTKSCVQTLEGHTHNISAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAVGYMKG-S 283
           **************************************************************99444.4 PP
   S: 278  nvlvlgsedskvn 290
           + +v g ++++++
   Q: 284  RRMVIGYDEGTIM 296
           5555555556655 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK FAQRSERVKS VDLHPTEPWI LASLYSGTLC IWDYQTQTMV KSFEVSELPV 60
RSAKFVSRKQ WVVAGADDMF IRVYNYNTMD KIKVFEAHTD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCACAAAA CCCCCTCCTC CCTCGCCTCC CCATCTCTCC TACCACCCCG CTTCGCTCCT 60
CCACCGAGCT CGCGCGATCC GGCTCGCCCC CTCGCCGCCT CGCCGCGCAG CGCCGCGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	88.97	0.00e+00	1625.00
IUUC-Ago-007914	Ashbya gossypii	46.86	0.00e+00	716.00
IUUC-Afu-008845	Aspergillus fumigatus	50.62	0.00e+00	888.00
IUUC-Ang-009654	Aspergillus niger	55.13	0.00e+00	813.00
IUUC-Bci-013866	Botrytis cinerea	53.14	0.00e+00	890.00
IUUC-Csa-023383	Chlorocebus sabaeus	65.26	0.00e+00	835.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	48.96	0.00e+00	797.00
IUUC-Ete-033166	Echinops telfairi	58.04	0.00e+00	701.00
IUUC-Fso-038268	Fusarium solani	51.70	0.00e+00	846.00
IUUC-Mtr-058618	Medicago truncatula	83.08	0.00e+00	1558.00
IUUC-Mdo-062076	Monodelphis domestica	59.41	0.00e+00	1110.00
IUUC-Osa-086026	Oryza sativa	92.67	0.00e+00	1691.00
IUUC-Ola-087245	Oryzias latipes	61.36	0.00e+00	1091.00
IUUC-Ppe-101470	Prunus persica	82.99	0.00e+00	1604.00
IUUC-Pte-104274	Pyrenophora teres	53.06	0.00e+00	894.00
IUUC-Sce-106269	Saccharomyces cerevisiae	46.68	0.00e+00	742.00
IUUC-Sha-106905	Sarcophilus harrisii	60.07	0.00e+00	1107.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	46.27	0.00e+00	769.00
IUUC-Sre-115040	Sporisorium reilianum	51.46	0.00e+00	875.00
IUUC-Tsy-118824	Tarsius syrichta	57.62	0.00e+00	787.00
IUUC-Vvi-131689	Vitis vinifera	85.70	0.00e+00	1556.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence