iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073363

UUCD1 version

UUC-OrA-00834

Ensembl Protein ID

ENSOANP00000021773.1

UniProt Accession

F7DKY8; F7DKY8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000013806.2	ENSOANT00000021776.1	ENSOANP00000021773.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.40e-111	372.4	301	928
ULD/UDP/UBQ/UBQ_Other	2.40e-12	46.8	143	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl NlgNtC+mNS+LQcLsni +l+e++l+ k++ ++n++np ++kge+++++++l++++w++++ +v pr+++++++++a++fsgy+
   Q: 301  CGLGNLGNTCFMNSALQCLSNIAPLTEYFLNdKYEAEINRDNPLGMKGEIAEAFAQLIKQMWSGRNAQVVPRMFKTQVGRFAPQFSGYQ 389
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+ e+++++   ++d      a++++  +n+s+i+d+F+g +ks+++c++c ++s++++pf++l
   Q: 390  QQDSQELLAFLLDGLHEDLNRVKKKPYLELQDAN--GRPDLvvakeAWDNHRLRNDSVIVDTFHGLFKSTLVCPQCSKISVTFDPFCYL 476
           ******************************8887..6666666777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p k+++ +e                                                                            
   Q: 477  TLPLPLKKDRTMEiflvsadphcrptqqyrvtvpmmgsvsdlcrslsklsgvaienmlvtdvynhrfhkifqmsdglnhimprddifvy 565
           ********99888**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 566  evfsstedgfecvtfpvyfrekknrqantssgtilygqpliisapkhklthdylyqiicerisryikyplmedssshpmasgtcngssg 654
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 655  tfevivveemehqnedrepptstvtcsfegrveeklgndpsryiskkitgqmykkklfsfslvnsygttdisslaadgkllklnsrstv 743
           ***************************************************************************************** PP
   S: 186  ......................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkR 236
                                                  l+dc+  ft+ e+l +++ +yc+ ckk+q+a+kk++l++lP++L++hLkR
   Q: 744  avdwdsetrslyydeqeseayekdgsmlqpqkkkkapvALRDCIGLFTTMETLGEHDPWYCPYCKKHQQATKKFDLWSLPKILVVHLKR 832
           ***************************************************************************************** PP
   S: 237  fsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevl 323
           fs++++   r k++++v+fp++ L +s+f ++p  +   +++Y+Liav +H+G ++ GHY+ay+kn  +gkW++fdDs+V+  +e++++
   Q: 833  FSYNRY--WRDKLDTQVDFPIRnLCMSEFICDPAAG---PYIYDLIAVSNHYGAMGVGHYTAYAKNrLNGKWYYFDDSNVSLASEDQIV 916
           *99885..567*********************9987...8**************************55677****************** PP
   S: 324  eetgstaYvlfYkrr 338
           +   + aYvlfY+rr
   Q: 917  T---KAAYVLFYQRR 928
           *...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgs.eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           ++++d +  l+++++++dt+a++ ++++++++ip   + rL++k      + L ++d+t++d gl++g+++++++++++
   Q: 143  CQNSDPTnLLSCQFSKADTIATIEKEMRRLFNIPdDKETRLWNKymsntYEQLnKPDNTIQDAGLYQGQVLVIELQNED 221
           56777777999***********************777*****999987744457*******************999876 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

QLRGRSQSRR GVHESRMNEI GKLDFKNSRR GVAGYLIDSR WFKQWKKYVG YDSWDMYHVG 60
EQNLYPGPID NSGLFSDPEN QILKDHLIDE LDYVLVPAEA WNKLVNWYGC IEGQQPIVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTGAGAG GTAGGAGCCA ATCCAGGAGA GGTGAGTGGC CCTTTGAGAA GACTAATATG 60
GAGGCTCAGA GATAACGAAG AGGTCAAGTA GGATTTTAAT GGATAGTTTG TGAAGTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0031397--P:negative regulation of protein ubiquitination
GO:0016579--P:protein deubiquitination
GO:0034394--P:protein localization to cell surface
GO:0031647--P:regulation of protein stability
GO:0000244--P:spliceosomal tri-snRNP complex assembly
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000425	Aegilops tauschii	38.97	9.00e-99	354.00
IUUC-Aml-001597	Ailuropoda melanoleuca	76.84	0.00e+00	1422.00
IUUC-Atr-002991	Amborella trichopoda	35.72	3.00e-139	488.00
IUUC-Apl-004068	Anas platyrhynchos	67.72	0.00e+00	1183.00
IUUC-Aca-004459	Anolis carolinensis	67.51	0.00e+00	1194.00
IUUC-Aly-006315	Arabidopsis lyrata	48.88	8.00e-76	278.00
IUUC-Ath-007343	Arabidopsis thaliana	36.80	2.00e-149	522.00
IUUC-Ago-007911	Ashbya gossypii	39.71	8.00e-64	238.00
IUUC-Afu-008878	Aspergillus fumigatus	34.60	2.00e-54	207.00
IUUC-Ang-009562	Aspergillus niger	44.33	2.00e-54	207.00
IUUC-Ame-011064	Astyanax mexicanus	62.62	0.00e+00	879.00
IUUC-Bta-012929	Bos taurus	76.50	0.00e+00	1424.00
IUUC-Bci-013993	Botrytis cinerea	47.49	3.00e-63	237.00
IUUC-Bdi-014013	Brachypodium distachyon	36.47	2.00e-148	519.00
IUUC-Bol-015244	Brassica oleracea	36.56	8.00e-148	517.00
IUUC-Bra-016885	Brassica rapa	35.93	4.00e-146	511.00
IUUC-Cja-018798	Callithrix jacchus	75.67	0.00e+00	1401.00
IUUC-Cfa-020599	Canis familiaris	77.15	0.00e+00	1427.00
IUUC-Cpo-022144	Cavia porcellus	76.18	0.00e+00	1418.00
IUUC-Csa-023770	Chlorocebus sabaeus	78.01	0.00e+00	1365.00
IUUC-Cho-024595	Choloepus hoffmanni	69.39	0.00e+00	930.00
IUUC-Cin-025292	Ciona intestinalis	41.39	0.00e+00	711.00
IUUC-Csv-026109	Ciona savignyi	42.12	0.00e+00	700.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	42.91	1.00e-60	228.00
IUUC-Cne-026852	Cryptococcus neoformans	40.50	2.00e-71	264.00
IUUC-Dre-027869	Danio rerio	64.65	0.00e+00	1169.00
IUUC-Dno-029316	Dasypus novemcinctus	75.16	0.00e+00	1429.00
IUUC-Dor-031038	Dipodomys ordii	71.89	0.00e+00	702.00
IUUC-Ete-032970	Echinops telfairi	72.42	0.00e+00	895.00
IUUC-Eca-034012	Equus caballus	77.32	0.00e+00	1409.00
IUUC-Eeu-035158	Erinaceus europaeus	65.98	0.00e+00	689.00
IUUC-Fca-035373	Felis catus	75.24	0.00e+00	1418.00
IUUC-Fal-037634	Ficedula albicollis	71.02	0.00e+00	1267.00
IUUC-Gmo-038866	Gadus morhua	62.96	0.00e+00	813.00
IUUC-Ggr-039740	Gaeumannomyces graminis	42.76	1.00e-59	225.00
IUUC-Gga-040729	Gallus gallus	67.75	0.00e+00	1201.00
IUUC-Gac-042631	Gasterosteus aculeatus	66.88	0.00e+00	1182.00
IUUC-Gma-043077	Glycine max	37.22	1.00e-148	520.00
IUUC-Ggo-045337	Gorilla gorilla	77.59	0.00e+00	1266.00
IUUC-Hsa-045669	Homo sapiens	76.99	0.00e+00	1415.00
IUUC-Hvu-047108	Hordeum vulgare	49.83	7.00e-78	284.00
IUUC-Itr-048610	Ictidomys tridecemlineatus	76.22	0.00e+00	1425.00
IUUC-Lch-050533	Latimeria chalumnae	66.10	0.00e+00	1142.00
IUUC-Lpe-051424	Leersia perrieri	36.32	5.00e-148	518.00
IUUC-Loc-051800	Lepisosteus oculatus	64.42	0.00e+00	1238.00
IUUC-Lma-052981	Leptosphaeria maculans	36.87	6.00e-61	230.00
IUUC-Laf-053803	Loxodonta africana	76.38	0.00e+00	1444.00
IUUC-Mcc-055556	Macaca mulatta	73.74	0.00e+00	1326.00
IUUC-Meu-056742	Macropus eugenii	73.57	0.00e+00	1284.00
IUUC-Mor-056985	Magnaporthe oryzae	43.07	6.00e-60	226.00
IUUC-Mpo-057486	Magnaporthe poae	43.82	8.00e-60	225.00
IUUC-Mtr-058489	Medicago truncatula	41.52	1.00e-117	416.00
IUUC-Mla-058848	Melampsora laricipopulina	33.04	5.00e-76	279.00
IUUC-Mga-059300	Meleagris gallopavo	68.49	0.00e+00	1183.00
IUUC-Mmr-061105	Microcebus murinus	56.01	0.00e+00	1036.00
IUUC-Mdo-061848	Monodelphis domestica	79.52	0.00e+00	1480.00
IUUC-Mmu-063960	Mus musculus	76.86	0.00e+00	1393.00
IUUC-Mac-065239	Musa acuminata	32.22	3.00e-125	442.00
IUUC-Mpu-066920	Mustela putorius furo	77.43	0.00e+00	1429.00
IUUC-Mlu-068088	Myotis lucifugus	75.28	0.00e+00	1402.00
IUUC-Nfi-068330	Neosartorya fischeri	44.68	1.00e-53	205.00
IUUC-Ncr-068879	Neurospora crassa	42.02	4.00e-61	229.00
IUUC-Nle-070010	Nomascus leucogenys	76.88	0.00e+00	1415.00
IUUC-Opr-070740	Ochotona princeps	74.40	0.00e+00	1037.00
IUUC-Ont-072573	Oreochromis niloticus	63.58	0.00e+00	1204.00
IUUC-Ocu-074242	Oryctolagus cuniculus	72.17	0.00e+00	1317.00
IUUC-Oba-075553	Oryza barthii	41.78	3.00e-126	445.00
IUUC-Obr-076902	Oryza brachyantha	37.32	5.00e-144	504.00
IUUC-Ogl-077583	Oryza glaberrima	41.78	3.00e-126	445.00
IUUC-Ogu-077990	Oryza glumaepatula	40.99	2.00e-121	429.00
IUUC-Oin-079300	Oryza indica	41.94	3.00e-127	449.00
IUUC-Olo-080315	Oryza longistaminata	36.52	2.00e-142	499.00
IUUC-Ome-081271	Oryza meridionalis	36.24	7.00e-144	504.00
IUUC-Oni-082303	Oryza nivara	41.14	2.00e-121	429.00
IUUC-Opu-083770	Oryza punctata	41.73	7.00e-124	437.00
IUUC-Oru-085141	Oryza rufipogon	41.55	2.00e-123	436.00
IUUC-Osa-085641	Oryza sativa	41.94	3.00e-127	449.00
IUUC-Ola-086553	Oryzias latipes	64.66	0.00e+00	1217.00
IUUC-Olu-087717	Ostreococcus lucimarinus	39.34	6.00e-124	437.00
IUUC-Oga-088562	Otolemur garnettii	70.43	0.00e+00	1249.00
IUUC-Oar-090439	Ovis aries	77.09	0.00e+00	1417.00
IUUC-Ptr-090801	Pan troglodytes	76.88	0.00e+00	1412.00
IUUC-Pan-092717	Papio anubis	72.89	0.00e+00	1294.00
IUUC-Psi-093942	Pelodiscus sinensis	70.84	0.00e+00	1276.00
IUUC-Pma-094533	Petromyzon marinus	55.40	0.00e+00	1021.00
IUUC-Pfo-097110	Poecilia formosa	56.86	0.00e+00	1038.00
IUUC-Pab-098522	Pongo abelii	76.48	0.00e+00	1038.00
IUUC-Pop-099801	Populus trichocarpa	37.70	3.00e-150	525.00
IUUC-Pca-100161	Procavia capensis	68.76	0.00e+00	1225.00
IUUC-Ppe-101587	Prunus persica	37.15	2.00e-146	512.00
IUUC-Pva-102158	Pteropus vampyrus	72.69	0.00e+00	674.00
IUUC-Pte-104102	Pyrenophora teres	34.76	6.00e-56	213.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	40.79	9.00e-55	209.00
IUUC-Rno-106081	Rattus norvegicus	74.25	0.00e+00	1431.00
IUUC-Sha-106937	Sarcophilus harrisii	79.26	0.00e+00	1491.00
IUUC-Smo-109356	Selaginella moellendorffii	45.88	5.00e-76	278.00
IUUC-Sit-109948	Setaria italica	36.02	2.00e-135	476.00
IUUC-Sly-111746	Solanum lycopersicum	37.79	1.00e-150	526.00
IUUC-Stu-112671	Solanum tuberosum	37.34	1.00e-147	516.00
IUUC-Sar-113542	Sorex araneus	72.20	0.00e+00	1335.00
IUUC-Sbi-114874	Sorghum bicolor	36.31	6.00e-142	497.00
IUUC-Sre-115130	Sporisorium reilianum	42.62	3.00e-76	280.00
IUUC-Ssc-115637	Sus scrofa	76.88	0.00e+00	1416.00
IUUC-Tgu-117267	Taeniopygia guttata	68.80	0.00e+00	1246.00
IUUC-Tru-118634	Takifugu rubripes	66.24	0.00e+00	1152.00
IUUC-Tsy-119117	Tarsius syrichta	50.79	4.00e-174	604.00
IUUC-Tca-121001	Theobroma cacao	36.51	2.00e-152	532.00
IUUC-Tae-125295	Triticum aestivum	36.32	2.00e-145	509.00
IUUC-Tur-126149	Triticum urartu	38.97	2.00e-98	353.00
IUUC-Tme-127062	Tuber melanosporum	32.37	2.00e-76	280.00
IUUC-Tbe-127669	Tupaia belangeri	61.93	0.00e+00	758.00
IUUC-Ttr-128778	Tursiops truncatus	77.47	0.00e+00	1403.00
IUUC-Uma-129498	Ustilago maydis	42.18	3.00e-70	260.00
IUUC-Vda-129781	Verticillium dahliae	41.64	1.00e-62	235.00
IUUC-Vpa-130571	Vicugna pacos	81.16	0.00e+00	993.00
IUUC-Vvi-131010	Vitis vinifera	37.70	2.00e-145	509.00
IUUC-Xtr-132305	Xenopus tropicalis	65.10	0.00e+00	1216.00
IUUC-Xma-133176	Xiphophorus maculatus	68.79	0.00e+00	802.00
IUUC-Yli-134392	Yarrowia lipolytica	39.58	5.00e-62	233.00
IUUC-Zma-135699	Zea mays	35.88	1.00e-142	500.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence