iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008883

Ensembl Protein ID

CADAFUAP00002255

UniProt Accession

Q4WMB3; Q4WMB3_ASPFU

Genbank Protein ID

EAL88901.1

Protein Name

Ubiquitin-like activating enzyme (UbaB), putative

Genbank Nucleotide ID

AAHF01000006

Gene Name

AFUA_6G10510

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00002255	CADAFUAT00002255	CADAFUAP00002255

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.50e-102	342.9	16	444

Active Site

Position(s)	Description	Evidence
176	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 14   eklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivF 106
           +++k+++vllvGagg+GcEllKnL l+G+g+i+++D dt+++snlnrqFLfr e+++k+KA va+e ++++ p+ ++ea++ +i++ + ++ +
   Q: 16   RRIKESRVLLVGAGGIGCELLKNLLLSGFGEIHIIDLDTIDLSNLNRQFLFRYEHIKKPKALVAKEVAHKFQPNAKLEAYHANIKDSQFNVDW 108
           79****************************************************************************************99* PP
   S: 107  fkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa..vlfnkll 197
           f +fd+V++aldn++arr+vnr+cl+a+vpliesgt+G+ Gqv+vi k  tecy+c+ ++  k++P+ct+++tp+++ h+i+wa  +l+ +l+
   Q: 109  FATFDLVFNALDNLDARRHVNRMCLAANVPLIESGTTGFNGQVQVIKKNQTECYDCNSKEVPKSFPVCTIRSTPSQPIHCIVWAksYLLPELF 201
           **************************************************************************************9999999 PP
   S: 198  eeeageeevlekldseekeegkdkvkselks.........edeenfeeaiei.avkafakttinsikqllksfecdivtkskspfwv...... 274
           ++++ e+e+ + +  ++  +gk++ +s++ +         e  +  +ea+++ a+++   + +   k + k f+ di + +++++++      
   Q: 202  GTSEDESEEFDHS--ADADNGKHLWSSNVSQasynpeaaaEIANLRKEAQALkAIRESMGSPEFYQKVFEKVFKEDIERLRGMEDMWksrtap 292
           9988888777754..4555555555555444333344433111112222222133444444444578899*****************999999 PP
   S: 275  .........................sfcsnaealqvpekvekdeevvkasap............lylllralerfek..kkgrkpgelsfekd 328
                                                ++ ++d+ v+k+  +            l+ l r+l+++++  k+g+kp  l f+kd
   Q: 293  qpldfeklqqesssiepiisvndqkV-----------WSSAEDFVVFKDRFEtpslmtilheqyLERLSRRLKTLQEtaKDGLKP-ILFFDKD 373
           88866655555555444433333331...........555555555444444555555555556888888888887522678888.8999*** PP
   S: 329  ddsavdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknffl 400
           d + +d+vta anlra+ +giep  +++++k++agniipaiattna+ +Gl++++++Kv++ +f++ k +fl
   Q: 374  DVDTLDFVTASANLRATIFGIEP-KSKFDTKQMAGNIIPAIATTNAMTAGLCVLQAFKVLKDDFQNAKMVFL 444
           *99********************.***************************************999887775 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MARDAYLKRS LGTLSRRIKE SRVLLVGAGG IGCELLKNLL LSGFGEIHII DLDTIDLSNL 60
NRQFLFRYEH IKKPKALVAK EVAHKFQPNA KLEAYHANIK DSQFNVDWFA TFDLVFNALD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGAGGG ACGCTTATCT TAAGCGTTCC CTCGGAACAC TCTCCAGGCG CATCAAAGAG 60
GTAGCTATAT CCCACCCTAC GCTTACTTTC GCAATGTGCT CGTACTCGCG ACCGCTGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR019572--UBA_E1_Cys
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF10585--UBA_e1_thiolCys

Gene Ontology

GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

KEGG

afm:AFUA_6G10510

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.57	5.00e-105	373.00
IUUC-Aml-001662	Ailuropoda melanoleuca	39.79	7.00e-101	359.00
IUUC-Atr-002636	Amborella trichopoda	39.50	2.00e-105	374.00
IUUC-Apl-003369	Anas platyrhynchos	40.15	9.00e-94	335.00
IUUC-Aca-004490	Anolis carolinensis	40.38	3.00e-85	308.00
IUUC-Aly-006359	Arabidopsis lyrata	39.61	2.00e-96	344.00
IUUC-Ath-007667	Arabidopsis thaliana	41.21	7.00e-101	359.00
IUUC-Ago-007844	Ashbya gossypii	38.90	8.00e-94	336.00
IUUC-Acl-008270	Aspergillus clavatus	83.62	0.00e+00	996.00
IUUC-Afl-008674	Aspergillus flavus	78.98	0.00e+00	1028.00
IUUC-Ani-009500	Aspergillus nidulans	71.72	0.00e+00	915.00
IUUC-Ang-009535	Aspergillus niger	76.35	0.00e+00	964.00
IUUC-Aor-010223	Aspergillus oryzae	78.63	0.00e+00	990.00
IUUC-Ate-010282	Aspergillus terreus	71.10	0.00e+00	859.00
IUUC-Ame-011736	Astyanax mexicanus	42.99	8.00e-110	389.00
IUUC-Bgr-012166	Blumeria graminis	52.60	5.00e-175	605.00
IUUC-Bta-012589	Bos taurus	39.72	6.00e-102	363.00
IUUC-Bci-013802	Botrytis cinerea	54.52	0.00e+00	679.00
IUUC-Bdi-014697	Brachypodium distachyon	40.97	8.00e-103	365.00
IUUC-Bol-016315	Brassica oleracea	39.46	2.00e-100	358.00
IUUC-Bra-017009	Brassica rapa	39.64	2.00e-100	358.00
IUUC-Cel-018708	Caenorhabditis elegans	38.18	1.00e-93	335.00
IUUC-Cja-019120	Callithrix jacchus	39.50	2.00e-101	361.00
IUUC-Cfa-021061	Canis familiaris	39.72	1.00e-101	362.00
IUUC-Cpo-021842	Cavia porcellus	39.15	1.00e-100	358.00
IUUC-Csa-024104	Chlorocebus sabaeus	39.50	1.00e-101	361.00
IUUC-Cho-024332	Choloepus hoffmanni	39.96	1.00e-84	305.00
IUUC-Cin-025363	Ciona intestinalis	40.16	3.00e-95	340.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	53.70	3.00e-174	603.00
IUUC-Cne-026888	Cryptococcus neoformans	43.43	2.00e-104	371.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.01	4.00e-57	214.00
IUUC-Dre-028420	Danio rerio	43.30	3.00e-109	387.00
IUUC-Dno-030041	Dasypus novemcinctus	39.50	7.00e-102	362.00
IUUC-Dse-031504	Dothistroma septosporum	45.47	2.00e-156	544.00
IUUC-Dme-031771	Drosophila melanogaster	63.78	4.00e-65	240.00
IUUC-Ete-033037	Echinops telfairi	37.19	5.00e-90	323.00
IUUC-Eca-033774	Equus caballus	39.23	8.00e-96	342.00
IUUC-Eeu-035074	Erinaceus europaeus	33.94	1.00e-55	209.00
IUUC-Fca-036508	Felis catus	39.13	9.00e-96	342.00
IUUC-Fal-036813	Ficedula albicollis	39.93	8.00e-96	342.00
IUUC-Fox-038056	Fusarium oxysporum	54.20	0.00e+00	627.00
IUUC-Fso-038223	Fusarium solani	54.02	7.00e-175	605.00
IUUC-Gmo-038526	Gadus morhua	40.37	1.00e-96	345.00
IUUC-Ggr-039767	Gaeumannomyces graminis	58.32	4.00e-166	576.00
IUUC-Gga-040981	Gallus gallus	41.35	5.00e-97	347.00
IUUC-Gac-041437	Gasterosteus aculeatus	41.41	2.00e-108	384.00
IUUC-Gma-043041	Glycine max	41.55	2.00e-109	387.00
IUUC-Ggo-045358	Gorilla gorilla	38.65	9.00e-98	349.00
IUUC-Hsa-046068	Homo sapiens	39.50	1.00e-101	361.00
IUUC-Hvu-047646	Hordeum vulgare	40.04	5.00e-103	366.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	39.82	6.00e-101	359.00
IUUC-Kpa-049301	Komagataella pastoris	63.76	1.00e-48	185.00
IUUC-Lch-049565	Latimeria chalumnae	41.19	2.00e-108	384.00
IUUC-Lpe-050884	Leersia perrieri	40.16	7.00e-102	362.00
IUUC-Loc-052493	Lepisosteus oculatus	42.20	6.00e-111	392.00
IUUC-Lma-053117	Leptosphaeria maculans	59.03	0.00e+00	646.00
IUUC-Laf-054518	Loxodonta africana	38.97	7.00e-100	356.00
IUUC-Mcc-055334	Macaca mulatta	39.50	2.00e-101	361.00
IUUC-Mor-057137	Magnaporthe oryzae	55.67	3.00e-149	520.00
IUUC-Mpo-057449	Magnaporthe poae	54.70	4.00e-169	586.00
IUUC-Mtr-058045	Medicago truncatula	41.18	2.00e-108	384.00
IUUC-Mla-058864	Melampsora laricipopulina	45.51	4.00e-99	353.00
IUUC-Mga-059422	Meleagris gallopavo	38.60	4.00e-75	273.00
IUUC-Mvi-060536	Microbotryum violaceum	57.24	4.00e-99	353.00
IUUC-Mmr-061161	Microcebus murinus	39.20	4.00e-100	357.00
IUUC-Mdo-061802	Monodelphis domestica	38.71	1.00e-102	365.00
IUUC-Mmu-064357	Mus musculus	40.41	2.00e-109	387.00
IUUC-Mac-065475	Musa acuminata	39.09	7.00e-103	366.00
IUUC-Mpu-066895	Mustela putorius furo	40.25	9.00e-102	362.00
IUUC-Mlu-067862	Myotis lucifugus	39.68	8.00e-105	372.00
IUUC-Nfi-068385	Neosartorya fischeri	92.08	0.00e+00	1132.00
IUUC-Ncr-068885	Neurospora crassa	55.31	0.00e+00	650.00
IUUC-Nle-069524	Nomascus leucogenys	39.10	8.00e-99	352.00
IUUC-Opr-071038	Ochotona princeps	40.28	4.00e-109	387.00
IUUC-Ont-071719	Oreochromis niloticus	41.07	3.00e-111	394.00
IUUC-Oan-072877	Ornithorhynchus anatinus	39.70	1.00e-92	331.00
IUUC-Ocu-074080	Oryctolagus cuniculus	39.32	4.00e-101	360.00
IUUC-Oba-075936	Oryza barthii	40.37	2.00e-102	364.00
IUUC-Obr-076841	Oryza brachyantha	40.97	6.00e-103	366.00
IUUC-Ogl-077686	Oryza glaberrima	40.08	1.00e-103	368.00
IUUC-Ogu-078597	Oryza glumaepatula	39.17	1.00e-99	355.00
IUUC-Oin-079791	Oryza indica	40.37	2.00e-102	364.00
IUUC-Olo-081009	Oryza longistaminata	40.37	1.00e-102	365.00
IUUC-Ome-081327	Oryza meridionalis	37.06	2.00e-95	341.00
IUUC-Oni-082334	Oryza nivara	39.41	4.00e-100	357.00
IUUC-Opu-083447	Oryza punctata	40.57	6.00e-103	366.00
IUUC-Oru-084977	Oryza rufipogon	40.37	2.00e-102	364.00
IUUC-Osa-086160	Oryza sativa	42.99	9.00e-96	342.00
IUUC-Ola-087415	Oryzias latipes	40.48	1.00e-105	375.00
IUUC-Olu-087850	Ostreococcus lucimarinus	38.82	1.00e-100	358.00
IUUC-Oga-088434	Otolemur garnettii	39.15	3.00e-101	360.00
IUUC-Oar-089872	Ovis aries	38.94	2.00e-94	338.00
IUUC-Ptr-091212	Pan troglodytes	39.50	1.00e-101	361.00
IUUC-Pan-092708	Papio anubis	61.02	3.00e-62	230.00
IUUC-Psi-093703	Pelodiscus sinensis	38.78	1.00e-94	338.00
IUUC-Pno-094953	Phaeosphaeria nodorum	56.14	0.00e+00	659.00
IUUC-Ppa-095963	Physcomitrella patens	41.65	8.00e-96	342.00
IUUC-Pfo-097515	Poecilia formosa	41.06	1.00e-107	381.00
IUUC-Pab-097951	Pongo abelii	36.66	3.00e-75	273.00
IUUC-Pop-099703	Populus trichocarpa	35.26	3.00e-94	337.00
IUUC-Pca-100426	Procavia capensis	40.39	3.00e-103	367.00
IUUC-Ppe-101152	Prunus persica	40.68	1.00e-107	381.00
IUUC-Pva-102792	Pteropus vampyrus	38.37	5.00e-94	336.00
IUUC-Pgr-103592	Puccinia graminis	41.57	7.00e-117	412.00
IUUC-Ptt-103805	Puccinia triticina	39.76	5.00e-97	346.00
IUUC-Pte-104215	Pyrenophora teres	57.23	0.00e+00	709.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	58.23	0.00e+00	721.00
IUUC-Rno-106117	Rattus norvegicus	40.34	1.00e-109	388.00
IUUC-Sce-106177	Saccharomyces cerevisiae	40.00	4.00e-92	330.00
IUUC-Sha-107006	Sarcophilus harrisii	38.75	2.00e-102	365.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	48.53	3.00e-140	490.00
IUUC-Spo-108020	Schizosaccharomyces pombe	51.32	4.00e-135	473.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	60.27	0.00e+00	672.00
IUUC-Smo-108809	Selaginella moellendorffii	42.83	8.00e-95	339.00
IUUC-Sit-110581	Setaria italica	40.40	7.00e-106	376.00
IUUC-Sly-111870	Solanum lycopersicum	40.07	2.00e-103	368.00
IUUC-Stu-112283	Solanum tuberosum	39.75	8.00e-104	369.00
IUUC-Sar-113432	Sorex araneus	58.02	2.00e-40	159.00
IUUC-Sbi-114075	Sorghum bicolor	41.38	2.00e-105	374.00
IUUC-Sre-114926	Sporisorium reilianum	43.84	5.00e-123	433.00
IUUC-Ssc-116281	Sus scrofa	61.02	2.00e-61	226.00
IUUC-Tgu-117247	Taeniopygia guttata	40.52	5.00e-96	343.00
IUUC-Tru-118075	Takifugu rubripes	40.78	2.00e-96	344.00
IUUC-Tsy-119398	Tarsius syrichta	62.90	5.00e-42	164.00
IUUC-Tni-120771	Tetraodon nigroviridis	37.69	1.00e-80	292.00
IUUC-Tca-121651	Theobroma cacao	40.59	4.00e-108	383.00
IUUC-Tre-122224	Trichoderma reesei	57.68	2.00e-163	567.00
IUUC-Tvi-122634	Trichoderma virens	59.86	7.00e-163	565.00
IUUC-Tae-125665	Triticum aestivum	40.65	1.00e-103	369.00
IUUC-Tur-126417	Triticum urartu	39.38	1.00e-104	372.00
IUUC-Tme-127016	Tuber melanosporum	56.54	2.00e-169	587.00
IUUC-Tbe-127678	Tupaia belangeri	62.90	9.00e-42	163.00
IUUC-Ttr-128598	Tursiops truncatus	38.23	4.00e-95	340.00
IUUC-Uma-129612	Ustilago maydis	43.16	8.00e-107	379.00
IUUC-Vda-129811	Verticillium dahliae	55.37	4.00e-165	572.00
IUUC-Vpa-130732	Vicugna pacos	31.98	1.00e-63	236.00
IUUC-Vvi-130832	Vitis vinifera	40.47	5.00e-99	353.00
IUUC-Xtr-132823	Xenopus tropicalis	42.30	3.00e-92	330.00
IUUC-Xma-133552	Xiphophorus maculatus	40.72	2.00e-106	377.00
IUUC-Yli-134666	Yarrowia lipolytica	43.83	1.00e-112	398.00
IUUC-Zma-135547	Zea mays	40.77	1.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence