iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048103

Ensembl Protein ID

ENSSTOP00000000395.2

UniProt Accession

I3LWM6; I3LWM6_ICTTR

Genbank Protein ID

ENSSTOP00000000395

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AGTP01029998

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000000442.2	ENSSTOT00000000441.2	ENSSTOP00000000395.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-06	26.2	187	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + +   s   ll+s+s+D+t+++W++r+g++l+
   Q: 187  GHTEFVSRI-LvvpSHpELLLSSSGDCTLRLWEYRSGRQLQ 226
           455555555.258644699*******************987 PP

Organism

Ictidomys tridecemlineatus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MASCAALAVC GQALVVRGGS RFLAVSTASS DDDSLFTYDC STAEKKPEEN KGEDGRPMDQ 60
GSDMILASTF STSGSYFALT DDSKRLILFR TKPWQCLSVR VVVRRCTALT FTASEERVLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGAGTT GCGCGGCGCT GGCGGTGTGC GGGCAGGCGC TGGTGGTGCG GGGTGGCAGC 60
CGGTTCCTGG CCGTCTCCAC TGCGAGCAGG TGAGGGAGTG GGCGGGCAGT GCGGGCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	28.57	8.00e-14	71.20
IUUC-Apl-003975	Anas platyrhynchos	58.70	7.00e-122	430.00
IUUC-Aca-005170	Anolis carolinensis	53.96	2.00e-105	375.00
IUUC-Aly-005769	Arabidopsis lyrata	31.73	8.00e-27	114.00
IUUC-Ath-006733	Arabidopsis thaliana	31.33	6.00e-26	111.00
IUUC-Acl-008151	Aspergillus clavatus	36.18	3.00e-15	76.30
IUUC-Afl-008518	Aspergillus flavus	35.83	4.00e-17	82.00
IUUC-Afu-009102	Aspergillus fumigatus	34.88	3.00e-13	69.70
IUUC-Ani-009442	Aspergillus nidulans	28.72	8.00e-16	78.20
IUUC-Aor-010133	Aspergillus oryzae	29.14	1.00e-19	90.90
IUUC-Ate-010465	Aspergillus terreus	38.52	1.00e-14	74.30
IUUC-Ame-010613	Astyanax mexicanus	46.30	5.00e-93	334.00
IUUC-Bgr-012067	Blumeria graminis	43.53	2.00e-17	83.60
IUUC-Bta-012788	Bos taurus	77.48	5.00e-178	616.00
IUUC-Bdi-014458	Brachypodium distachyon	31.45	1.00e-18	87.40
IUUC-Bol-015373	Brassica oleracea	31.44	9.00e-27	115.00
IUUC-Bra-016644	Brassica rapa	39.01	7.00e-25	109.00
IUUC-Cpo-021963	Cavia porcellus	81.48	5.00e-179	619.00
IUUC-Csa-024148	Chlorocebus sabaeus	80.39	7.00e-159	553.00
IUUC-Cne-026834	Cryptococcus neoformans	35.10	1.00e-19	90.90
IUUC-Dre-028427	Danio rerio	46.21	2.00e-94	338.00
IUUC-Dno-028881	Dasypus novemcinctus	71.02	6.00e-153	533.00
IUUC-Dor-030522	Dipodomys ordii	79.90	4.00e-173	600.00
IUUC-Dme-032136	Drosophila melanogaster	36.65	6.00e-23	101.00
IUUC-Fca-035833	Felis catus	76.09	1.00e-157	548.00
IUUC-Fal-037497	Ficedula albicollis	56.51	4.00e-120	424.00
IUUC-Gga-040547	Gallus gallus	56.91	3.00e-125	441.00
IUUC-Gac-041761	Gasterosteus aculeatus	44.41	3.00e-87	314.00
IUUC-Gma-043722	Glycine max	30.71	3.00e-20	92.40
IUUC-Ggo-045340	Gorilla gorilla	80.15	2.00e-171	595.00
IUUC-Hsa-046403	Homo sapiens	80.15	8.00e-171	592.00
IUUC-Hvu-047643	Hordeum vulgare	32.52	4.00e-22	99.00
IUUC-Kpa-049283	Komagataella pastoris	33.33	3.00e-19	89.40
IUUC-Lch-050682	Latimeria chalumnae	52.71	5.00e-113	400.00
IUUC-Lpe-050712	Leersia perrieri	32.51	7.00e-26	111.00
IUUC-Loc-052599	Lepisosteus oculatus	53.11	2.00e-113	402.00
IUUC-Laf-054390	Loxodonta africana	76.76	3.00e-173	600.00
IUUC-Mcc-054747	Macaca mulatta	80.63	2.00e-166	578.00
IUUC-Mtr-058600	Medicago truncatula	32.37	1.00e-24	107.00
IUUC-Mla-059129	Melampsora laricipopulina	25.25	8.00e-12	63.90
IUUC-Mga-059876	Meleagris gallopavo	58.02	1.00e-124	439.00
IUUC-Mvi-060359	Microbotryum violaceum	30.98	1.00e-13	71.60
IUUC-Mmr-061518	Microcebus murinus	78.69	2.00e-173	601.00
IUUC-Mac-065417	Musa acuminata	27.80	2.00e-21	96.70
IUUC-Nfi-068402	Neosartorya fischeri	26.64	4.00e-14	72.80
IUUC-Nle-069914	Nomascus leucogenys	79.18	3.00e-160	557.00
IUUC-Ont-071555	Oreochromis niloticus	41.93	6.00e-82	297.00
IUUC-Oan-072951	Ornithorhynchus anatinus	66.32	9.00e-150	522.00
IUUC-Ocu-074679	Oryctolagus cuniculus	80.38	2.00e-169	587.00
IUUC-Oba-075355	Oryza barthii	28.69	4.00e-14	72.40
IUUC-Obr-076769	Oryza brachyantha	33.60	2.00e-26	113.00
IUUC-Ogl-077168	Oryza glaberrima	33.47	3.00e-26	112.00
IUUC-Ogu-078275	Oryza glumaepatula	27.57	9.00e-14	71.20
IUUC-Oin-079207	Oryza indica	33.47	3.00e-26	112.00
IUUC-Oni-082437	Oryza nivara	27.82	4.00e-13	69.30
IUUC-Opu-084031	Oryza punctata	33.47	4.00e-24	105.00
IUUC-Oru-084380	Oryza rufipogon	28.28	2.00e-13	70.10
IUUC-Osa-085327	Oryza sativa	33.06	2.00e-25	110.00
IUUC-Ola-086716	Oryzias latipes	44.09	1.00e-78	286.00
IUUC-Olu-087708	Ostreococcus lucimarinus	27.62	7.00e-15	74.30
IUUC-Oar-090239	Ovis aries	79.52	1.00e-172	598.00
IUUC-Ptr-090851	Pan troglodytes	80.39	2.00e-171	594.00
IUUC-Pan-092558	Papio anubis	80.48	9.00e-159	552.00
IUUC-Psi-093792	Pelodiscus sinensis	57.34	9.00e-132	462.00
IUUC-Ppa-095757	Physcomitrella patens	37.30	1.00e-23	103.00
IUUC-Pfo-096465	Poecilia formosa	43.98	7.00e-86	310.00
IUUC-Pab-097722	Pongo abelii	79.66	2.00e-170	591.00
IUUC-Pop-098979	Populus trichocarpa	35.48	5.00e-21	95.10
IUUC-Pca-100753	Procavia capensis	74.05	1.00e-114	405.00
IUUC-Ppe-101515	Prunus persica	33.47	7.00e-22	98.20
IUUC-Sja-107780	Schizosaccharomyces japonicus	25.71	2.00e-13	70.10
IUUC-Spo-108251	Schizosaccharomyces pombe	30.00	1.00e-14	73.60
IUUC-Smo-108938	Selaginella moellendorffii	37.82	8.00e-24	104.00
IUUC-Sit-110020	Setaria italica	31.17	9.00e-24	104.00
IUUC-Sly-111543	Solanum lycopersicum	28.63	5.00e-22	98.60
IUUC-Stu-111925	Solanum tuberosum	29.27	5.00e-22	98.60
IUUC-Sbi-114061	Sorghum bicolor	32.27	1.00e-23	103.00
IUUC-Tgu-117321	Taeniopygia guttata	56.14	3.00e-111	394.00
IUUC-Tru-118454	Takifugu rubripes	45.45	4.00e-85	307.00
IUUC-Tni-119894	Tetraodon nigroviridis	45.18	7.00e-79	286.00
IUUC-Tca-121746	Theobroma cacao	33.68	6.00e-21	95.10
IUUC-Tae-124114	Triticum aestivum	32.52	2.00e-22	100.00
IUUC-Tur-126254	Triticum urartu	27.80	1.00e-14	73.60
IUUC-Tbe-127683	Tupaia belangeri	52.67	4.00e-61	228.00
IUUC-Ttr-129056	Tursiops truncatus	74.46	3.00e-157	547.00
IUUC-Vvi-131428	Vitis vinifera	34.87	1.00e-22	100.00
IUUC-Xma-133605	Xiphophorus maculatus	42.28	2.00e-85	308.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence