iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087126

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

BAAF04103538

Gene Name

uchl5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000012257.1	ENSORLT00000015338.1	ENSORLP00000015337.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.20e-96	324.3	1	316

Active Site

Position(s)	Description	Evidence
88	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
164	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 1    mnsqvkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktif 89
           m++ + ew+ +esdPg+ft+l++ fg+k+  qvee++s++pen++ + +pv+gl++lFk+++ +e +          ++v+++ ++ if
   Q: 1    MSGSAGEWCLMESDPGVFTELIKGFGCKGA-QVEEIWSMEPENFENL-KPVHGLIFLFKWQPGEEPAG---------SIVQDSRLDHIF 78
           678889************************.****************.*******************9.........8899******** PP
   S: 90   fakqvigNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeaf 178
           fakqvi+N+Cat+A++svllnc++  + lG+tls+++e+++++++ +k+lal+n++v++++hns+ar+++++ + + +++    +++af
   Q: 79   FAKQVINNACATQAIVSVLLNCSHSDIVLGDTLSEFREFSQSFDAAMKGLALSNSEVIRQVHNSFARQQMFEFDAKSSAK----DEDAF 163
           **************************************************************************998777....79*** PP
   S: 179  hfvsyvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid........ 259
           hfvsyv++ngrlyeldgl++ P+dlg+ ++++++ ++++ v+   +ri++++++eirfnl+ iv+dr++i+++++  l+ +        
   Q: 164  HFVSYVPVNGRLYELDGLREGPIDLGA-CNQDDWINAVRPVI--EKRIQKYSEGEIRFNLMSIVSDRKMIYEKKIAELQAQltedepmd 249
           **************************9.78999*********..******************************988887788888888 PP
   S: 260  .keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveet 325
             +  ++l+ i+se++k++  +++e++k k++ki++irR++ny  fi++++k+la+ ++l  lve+ 
   Q: 250  tDQSSSFLSSIQSEIAKYQLLIEEENQKLKRYKIENIRRKHNYLPFIMELLKTLAEYQQLMPLVEKA 316
           766789**********************************************************984 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MSGSAGEWCL MESDPGVFTE LIKGFGCKGA QVEEIWSMEP ENFENLKPVH GLIFLFKWQP 60
GEEPAGSIVQ DSRLDHIFFA KQVINNACAT QAIVSVLLNC SHSDIVLGDT LSEFREFSQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGTGAAGT CACTATAGAT AATTAGCTTG TGTAGCGTTC GCGTTGCTAA TCTGTTAGCA 60
TCTTGATATA TGTGATTGAA ATAGGGACAT TTTAAAAGAC AATAAACATG TCTGGCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37
IPR033837--UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0031011--C:Ino80 complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ola:101155020

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	46.55	5.00e-82	297.00
IUUC-Aml-001866	Ailuropoda melanoleuca	89.46	7.00e-168	582.00
IUUC-Atr-002966	Amborella trichopoda	46.86	8.00e-80	290.00
IUUC-Apl-003306	Anas platyrhynchos	82.40	2.00e-165	575.00
IUUC-Aca-004763	Anolis carolinensis	91.67	2.00e-170	591.00
IUUC-Aly-005581	Arabidopsis lyrata	47.29	3.00e-79	288.00
IUUC-Ath-007283	Arabidopsis thaliana	46.99	5.00e-81	294.00
IUUC-Ago-007999	Ashbya gossypii	38.30	8.00e-33	134.00
IUUC-Acl-008231	Aspergillus clavatus	43.51	2.00e-53	202.00
IUUC-Afl-008557	Aspergillus flavus	38.03	6.00e-55	207.00
IUUC-Afu-008988	Aspergillus fumigatus	44.35	8.00e-54	203.00
IUUC-Ani-009420	Aspergillus nidulans	37.31	1.00e-53	203.00
IUUC-Ang-009859	Aspergillus niger	40.71	9.00e-50	190.00
IUUC-Aor-010145	Aspergillus oryzae	38.03	6.00e-55	207.00
IUUC-Ate-010347	Aspergillus terreus	42.29	5.00e-53	201.00
IUUC-Ame-010791	Astyanax mexicanus	93.62	0.00e+00	632.00
IUUC-Bgr-012298	Blumeria graminis	37.38	4.00e-49	187.00
IUUC-Bta-013251	Bos taurus	89.46	3.00e-166	577.00
IUUC-Bci-013786	Botrytis cinerea	37.46	2.00e-57	216.00
IUUC-Bdi-014132	Brachypodium distachyon	47.55	2.00e-78	285.00
IUUC-Bol-015611	Brassica oleracea	49.39	4.00e-82	298.00
IUUC-Bra-017769	Brassica rapa	49.39	5.00e-82	297.00
IUUC-Cel-018604	Caenorhabditis elegans	46.11	4.00e-80	291.00
IUUC-Cja-019768	Callithrix jacchus	81.52	2.00e-161	561.00
IUUC-Cfa-020207	Canis familiaris	89.46	7.00e-168	582.00
IUUC-Cpo-021925	Cavia porcellus	85.30	1.00e-158	552.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	44.01	5.00e-73	267.00
IUUC-Csa-023958	Chlorocebus sabaeus	89.46	1.00e-165	575.00
IUUC-Cho-024928	Choloepus hoffmanni	89.61	2.00e-38	152.00
IUUC-Cin-025771	Ciona intestinalis	54.97	2.00e-100	358.00
IUUC-Csv-026149	Ciona savignyi	57.37	1.00e-102	366.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	36.76	4.00e-51	194.00
IUUC-Cne-026955	Cryptococcus neoformans	36.28	2.00e-52	199.00
IUUC-Cme-027104	Cyanidioschyzon merolae	33.15	1.00e-48	186.00
IUUC-Dre-027409	Danio rerio	92.40	0.00e+00	625.00
IUUC-Dno-028921	Dasypus novemcinctus	88.82	7.00e-167	579.00
IUUC-Dse-031170	Dothistroma septosporum	37.66	3.00e-56	211.00
IUUC-Dme-031677	Drosophila melanogaster	60.62	1.00e-112	399.00
IUUC-Ete-032707	Echinops telfairi	62.07	4.00e-106	377.00
IUUC-Eca-033776	Equus caballus	89.58	9.00e-153	532.00
IUUC-Eeu-035305	Erinaceus europaeus	71.81	1.00e-76	279.00
IUUC-Fca-035846	Felis catus	82.35	1.00e-162	565.00
IUUC-Fal-037597	Ficedula albicollis	91.32	3.00e-149	520.00
IUUC-Fox-037670	Fusarium oxysporum	48.05	3.00e-53	201.00
IUUC-Fso-038243	Fusarium solani	48.05	3.00e-53	201.00
IUUC-Gmo-038499	Gadus morhua	89.78	2.00e-165	574.00
IUUC-Ggr-039975	Gaeumannomyces graminis	42.51	2.00e-48	185.00
IUUC-Gga-040904	Gallus gallus	90.63	8.00e-177	612.00
IUUC-Gac-042058	Gasterosteus aculeatus	94.89	2.00e-175	607.00
IUUC-Gma-043763	Glycine max	47.48	3.00e-84	305.00
IUUC-Ggo-044699	Gorilla gorilla	83.71	6.00e-151	526.00
IUUC-Hsa-046227	Homo sapiens	89.46	1.00e-167	582.00
IUUC-Hvu-047359	Hordeum vulgare	46.20	6.00e-81	293.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	81.40	3.00e-162	563.00
IUUC-Lch-049829	Latimeria chalumnae	91.05	2.00e-168	584.00
IUUC-Lpe-050899	Leersia perrieri	48.26	1.00e-75	276.00
IUUC-Loc-052264	Lepisosteus oculatus	92.36	7.00e-170	589.00
IUUC-Lma-053110	Leptosphaeria maculans	44.26	2.00e-47	182.00
IUUC-Laf-053639	Loxodonta africana	89.46	7.00e-168	582.00
IUUC-Mcc-055506	Macaca mulatta	89.46	1.00e-165	575.00
IUUC-Mor-057001	Magnaporthe oryzae	44.54	2.00e-54	205.00
IUUC-Mpo-057608	Magnaporthe poae	42.16	3.00e-33	134.00
IUUC-Mtr-057731	Medicago truncatula	48.66	7.00e-84	303.00
IUUC-Mla-059016	Melampsora laricipopulina	42.29	1.00e-42	166.00
IUUC-Mga-060178	Meleagris gallopavo	91.12	7.00e-163	565.00
IUUC-Mvi-060353	Microbotryum violaceum	38.81	5.00e-55	207.00
IUUC-Mmr-060738	Microcebus murinus	89.78	2.00e-168	584.00
IUUC-Mdo-062266	Monodelphis domestica	92.65	2.00e-115	407.00
IUUC-Mmu-063619	Mus musculus	88.18	2.00e-165	574.00
IUUC-Mac-065301	Musa acuminata	50.79	4.00e-88	317.00
IUUC-Mpu-066058	Mustela putorius furo	89.78	4.00e-168	583.00
IUUC-Mlu-067292	Myotis lucifugus	88.50	2.00e-164	571.00
IUUC-Nfi-068275	Neosartorya fischeri	38.59	4.00e-55	207.00
IUUC-Ncr-068713	Neurospora crassa	38.80	2.00e-58	218.00
IUUC-Nle-069013	Nomascus leucogenys	89.14	4.00e-165	573.00
IUUC-Opr-070628	Ochotona princeps	78.53	1.00e-151	529.00
IUUC-Ont-072688	Oreochromis niloticus	95.87	7.00e-177	612.00
IUUC-Oan-073004	Ornithorhynchus anatinus	89.43	5.00e-128	449.00
IUUC-Ocu-074303	Oryctolagus cuniculus	89.78	2.00e-168	585.00
IUUC-Oba-075002	Oryza barthii	48.49	2.00e-80	291.00
IUUC-Obr-076392	Oryza brachyantha	49.22	4.00e-78	284.00
IUUC-Ogl-077271	Oryza glaberrima	48.49	2.00e-80	291.00
IUUC-Ogu-078493	Oryza glumaepatula	48.49	3.00e-81	294.00
IUUC-Oin-080084	Oryza indica	48.49	3.00e-81	294.00
IUUC-Olo-080803	Oryza longistaminata	48.19	1.00e-80	293.00
IUUC-Ome-081146	Oryza meridionalis	48.19	1.00e-80	292.00
IUUC-Oni-082146	Oryza nivara	48.49	3.00e-81	294.00
IUUC-Opu-083633	Oryza punctata	49.53	3.00e-77	281.00
IUUC-Oru-084789	Oryza rufipogon	48.49	3.00e-81	294.00
IUUC-Osa-086196	Oryza sativa	48.49	3.00e-81	294.00
IUUC-Olu-087665	Ostreococcus lucimarinus	40.28	2.00e-67	248.00
IUUC-Oga-089140	Otolemur garnettii	82.06	2.00e-162	565.00
IUUC-Oar-090296	Ovis aries	88.82	3.00e-166	577.00
IUUC-Ptr-090566	Pan troglodytes	89.46	1.00e-167	582.00
IUUC-Pan-092052	Papio anubis	89.46	1.00e-165	575.00
IUUC-Psi-093723	Pelodiscus sinensis	92.01	1.00e-155	541.00
IUUC-Pma-094568	Petromyzon marinus	61.46	1.00e-107	382.00
IUUC-Pno-095120	Phaeosphaeria nodorum	44.59	6.00e-49	187.00
IUUC-Ppa-095761	Physcomitrella patens	47.66	5.00e-82	297.00
IUUC-Pfo-096210	Poecilia formosa	95.21	3.00e-177	613.00
IUUC-Pab-098463	Pongo abelii	89.46	2.00e-167	581.00
IUUC-Pop-099423	Populus trichocarpa	47.18	1.00e-83	302.00
IUUC-Pca-100108	Procavia capensis	89.02	2.00e-132	464.00
IUUC-Ppe-101176	Prunus persica	49.10	9.00e-83	300.00
IUUC-Pva-102629	Pteropus vampyrus	89.56	3.00e-136	477.00
IUUC-Pgr-103419	Puccinia graminis	38.41	6.00e-55	207.00
IUUC-Pte-104207	Pyrenophora teres	41.42	3.00e-31	127.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	37.70	4.00e-54	204.00
IUUC-Rno-105579	Rattus norvegicus	78.95	5.00e-145	506.00
IUUC-Sha-106894	Sarcophilus harrisii	88.41	8.00e-143	499.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	40.00	1.00e-57	216.00
IUUC-Spo-108371	Schizosaccharomyces pombe	41.05	2.00e-60	225.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	38.41	4.00e-48	184.00
IUUC-Smo-109396	Selaginella moellendorffii	52.00	2.00e-86	311.00
IUUC-Sit-110630	Setaria italica	49.24	7.00e-84	303.00
IUUC-Sly-110972	Solanum lycopersicum	48.57	3.00e-78	284.00
IUUC-Stu-112185	Solanum tuberosum	48.50	3.00e-88	318.00
IUUC-Sar-113294	Sorex araneus	73.79	2.00e-145	508.00
IUUC-Sbi-113951	Sorghum bicolor	49.54	3.00e-84	305.00
IUUC-Ssc-115501	Sus scrofa	88.55	1.00e-155	541.00
IUUC-Tgu-117152	Taeniopygia guttata	90.97	3.00e-149	520.00
IUUC-Tru-118388	Takifugu rubripes	94.57	7.00e-175	605.00
IUUC-Tsy-119109	Tarsius syrichta	89.78	5.00e-168	583.00
IUUC-Tni-120048	Tetraodon nigroviridis	94.89	1.00e-175	608.00
IUUC-Tca-121750	Theobroma cacao	48.22	6.00e-88	317.00
IUUC-Tre-122130	Trichoderma reesei	39.67	2.00e-55	209.00
IUUC-Tvi-122284	Trichoderma virens	39.13	1.00e-52	199.00
IUUC-Tae-124082	Triticum aestivum	47.42	1.00e-80	292.00
IUUC-Tur-126366	Triticum urartu	42.09	1.00e-64	239.00
IUUC-Tme-127187	Tuber melanosporum	40.92	2.00e-59	222.00
IUUC-Tbe-127619	Tupaia belangeri	80.14	1.00e-125	442.00
IUUC-Ttr-128867	Tursiops truncatus	81.22	8.00e-116	409.00
IUUC-Vda-129912	Verticillium dahliae	37.50	1.00e-53	202.00
IUUC-Vpa-130552	Vicugna pacos	91.87	3.00e-118	417.00
IUUC-Vvi-130881	Vitis vinifera	48.07	2.00e-82	298.00
IUUC-Xtr-131934	Xenopus tropicalis	83.28	3.00e-166	577.00
IUUC-Xma-133312	Xiphophorus maculatus	94.89	6.00e-176	609.00
IUUC-Yli-134487	Yarrowia lipolytica	37.55	3.00e-46	178.00
IUUC-Zma-135462	Zea mays	43.38	8.00e-71	260.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence