iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tur-126259

Ensembl Protein ID

TRIUR3_22901-P1

UniProt Accession

M8A9G6; M8A9G6_TRIUA

Genbank Protein ID

EMS68731.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

KD002795

Gene Name

TRIUR3_22901

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIUR3_22901	TRIUR3_22901-T1	TRIUR3_22901-P1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	34.88	2.00e-37	154.00	IUUC-Hsa-046357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Triticum urartu

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MASAAYTDDS GSEVIDPPKS EVLDVAELVG DHIQLTQKSN VVASSSVREL LECPVCLSAM 60
YPPIHQCSNG HTLCSGCKPR VHNRCPTCRH ELGNIRCLAL EKVAASLELP CKYQNFGCLG 120

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Nucleotide Sequence
(Fasta)

ATGGCCTCGG CTGCTTATAC TGATGATTCT GGTTCCGAGG TTATTGATCC TCCAAAGTCT 60
GAGGTACTGG ATGTTGCTGA ACTTGTCGGC GATCATATCC AGCTTACACA AAAATCAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	66.12	2.00e-120	424.00
IUUC-Aml-001186	Ailuropoda melanoleuca	34.88	4.00e-39	154.00
IUUC-Atr-003118	Amborella trichopoda	84.48	2.00e-148	517.00
IUUC-Aly-006522	Arabidopsis lyrata	80.46	2.00e-130	457.00
IUUC-Ath-007092	Arabidopsis thaliana	81.08	3.00e-131	460.00
IUUC-Ame-011196	Astyanax mexicanus	35.11	6.00e-40	156.00
IUUC-Bta-012887	Bos taurus	34.88	4.00e-39	154.00
IUUC-Bdi-014729	Brachypodium distachyon	80.84	4.00e-131	459.00
IUUC-Bol-015983	Brassica oleracea	79.85	5.00e-131	459.00
IUUC-Bra-016910	Brassica rapa	72.33	3.00e-132	463.00
IUUC-Cpo-022348	Cavia porcellus	34.88	4.00e-39	154.00
IUUC-Csa-023974	Chlorocebus sabaeus	34.88	4.00e-39	154.00
IUUC-Dre-028041	Danio rerio	35.11	6.00e-40	156.00
IUUC-Fca-035362	Felis catus	34.88	4.00e-39	154.00
IUUC-Fal-037487	Ficedula albicollis	34.88	4.00e-39	154.00
IUUC-Gac-042282	Gasterosteus aculeatus	35.11	5.00e-40	157.00
IUUC-Gma-042926	Glycine max	84.11	2.00e-153	533.00
IUUC-Ggo-045444	Gorilla gorilla	34.88	4.00e-39	154.00
IUUC-Hsa-046357	Homo sapiens	34.88	4.00e-39	154.00
IUUC-Hvu-047574	Hordeum vulgare	66.12	2.00e-120	424.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	34.88	4.00e-39	154.00
IUUC-Mcc-054640	Macaca mulatta	34.88	4.00e-39	154.00
IUUC-Mmr-060794	Microcebus murinus	34.88	4.00e-39	154.00
IUUC-Mac-065670	Musa acuminata	82.13	2.00e-133	467.00
IUUC-Mpu-066488	Mustela putorius furo	34.88	4.00e-39	154.00
IUUC-Nle-069706	Nomascus leucogenys	34.88	4.00e-39	154.00
IUUC-Ont-071849	Oreochromis niloticus	35.11	4.00e-40	157.00
IUUC-Ome-081318	Oryza meridionalis	66.56	2.00e-121	427.00
IUUC-Opu-084065	Oryza punctata	66.23	4.00e-121	426.00
IUUC-Ola-086814	Oryzias latipes	35.11	5.00e-40	157.00
IUUC-Oar-089323	Ovis aries	34.88	4.00e-39	154.00
IUUC-Ptr-090692	Pan troglodytes	34.88	4.00e-39	154.00
IUUC-Pan-092012	Papio anubis	34.88	4.00e-39	154.00
IUUC-Psi-093687	Pelodiscus sinensis	34.88	3.00e-39	154.00
IUUC-Pma-094387	Petromyzon marinus	33.98	5.00e-40	156.00
IUUC-Ppa-095212	Physcomitrella patens	79.93	1.00e-133	468.00
IUUC-Pfo-097134	Poecilia formosa	35.11	5.00e-40	157.00
IUUC-Pab-097555	Pongo abelii	34.88	4.00e-39	154.00
IUUC-Pop-100033	Populus trichocarpa	80.84	4.00e-131	459.00
IUUC-Ppe-101960	Prunus persica	80.84	1.00e-131	461.00
IUUC-Smo-109412	Selaginella moellendorffii	79.40	1.00e-131	461.00
IUUC-Sly-111259	Solanum lycopersicum	80.46	5.00e-130	456.00
IUUC-Stu-112474	Solanum tuberosum	82.68	2.00e-150	523.00
IUUC-Tca-121228	Theobroma cacao	85.86	3.00e-156	542.00
IUUC-Tae-123647	Triticum aestivum	66.12	2.00e-120	424.00
IUUC-Vvi-131233	Vitis vinifera	77.82	2.00e-127	447.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence