iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d007900	Zm00001d007900_T001	Zm00001d007900_T001
Zm00001d007900	Zm00001d007900_T003	Zm00001d007900_T003

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-22	79.9	189	227
UBD/Beta-Prp	3.10e-40	140.2	6	255

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtc....lafsdtllvsGsdDgtikvWDlrtgvllk 37
           gH+  +++    l++   ++++Gs D++ k+WD+rt +l+k
   Q: 189  GHQKTISSlsksLDW--SHFITGSLDKSAKLWDTRTLTLIK 227
           566666662222577..79****************998876 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...... 131
           ++ghe + t +++++dg++l ++++D+t  vw  ++g+ + t++gh+  v+++++s+++ +l++Gs+d+t+++w+++tg++l +      
   Q: 6    MKGHERPLTFLRYNRDGDLLFSCAKDHTPTVWYADNGDRLGTYRGHNGAVWTCDVSRDSARLITGSADQTAKLWEVSTGKELFSfrfdap 95
           4899999**************************************************99**********************999999*** PP
   S: 132  .............................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl. 175
                                                        + +g +g +n +v+ p ++ +++++ D t+r+Wd++tg+ll++  
   Q: 96   arsvefaigdalavvttdnfmdhvptvqvkriaediddqteesalVITGIKGRINRAVWGPLNRTIITAGEDATIRIWDSETGQLLKESd 185
           *******************************************99********************************************9 PP
   S: 176  .tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs.sDg 244
            ++gh++ + sls + +  ++++gsld++ klwd +t + ++t+   +++v+ v+ sp ++ +v g+ +D 
   Q: 186  kESGHQKTISSLSKSLDWSHFITGSLDKSAKLWDTRTLTLIKTYVT-ERPVNAVDISPTHDTVVLGGgQDA 255
           9777***************************************996.568999999977777777763443 PP

Organism

Zea mays

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLRYNR DGDLLFSCAK DHTPTVWYAD NGDRLGTYRG HNGAVWTCDV 60
SRDSARLITG SADQTAKLWE VSTGKELFSF RFDAPARSVE FAIGDALAVV TTDNFMDHVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCTAACGC CGACGCCTGG TGCCGACTGC CGAGGCCTTC GCTGGTTACT AGCACCGCCC 60
CAGCTCCTTC TCCCTTTTCC GGCGGAGGTG AACACCGCCA CCACTAGAGC GCCACGATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

zma:103648258

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002468	Amborella trichopoda	71.19	3.00e-96	343.00
IUUC-Aly-005473	Arabidopsis lyrata	75.91	1.00e-150	525.00
IUUC-Ago-008000	Ashbya gossypii	41.89	6.00e-75	273.00
IUUC-Bdi-015019	Brachypodium distachyon	88.34	1.00e-174	605.00
IUUC-Cne-026838	Cryptococcus neoformans	43.50	4.00e-78	284.00
IUUC-Dre-028567	Danio rerio	44.79	7.00e-86	310.00
IUUC-Dse-031191	Dothistroma septosporum	45.29	2.00e-80	292.00
IUUC-Fox-037860	Fusarium oxysporum	46.44	2.00e-82	298.00
IUUC-Ggr-040045	Gaeumannomyces graminis	46.75	2.00e-83	301.00
IUUC-Gma-043246	Glycine max	81.29	9.00e-161	558.00
IUUC-Kpa-049325	Komagataella pastoris	45.26	1.00e-79	288.00
IUUC-Lma-053047	Leptosphaeria maculans	47.99	5.00e-85	306.00
IUUC-Meu-056729	Macropus eugenii	41.90	2.00e-75	275.00
IUUC-Mor-057025	Magnaporthe oryzae	46.60	5.00e-81	293.00
IUUC-Mtr-058051	Medicago truncatula	80.06	4.00e-159	553.00
IUUC-Ncr-068820	Neurospora crassa	47.37	7.00e-83	300.00
IUUC-Oni-082411	Oryza nivara	80.06	3.00e-152	530.00
IUUC-Psi-094096	Pelodiscus sinensis	43.58	1.00e-50	192.00
IUUC-Pno-094988	Phaeosphaeria nodorum	44.27	4.00e-74	271.00
IUUC-Ppa-095949	Physcomitrella patens	73.31	2.00e-146	511.00
IUUC-Ppe-101320	Prunus persica	80.67	4.00e-160	556.00
IUUC-Sbi-114063	Sorghum bicolor	98.16	0.00e+00	665.00
IUUC-Tca-121316	Theobroma cacao	80.98	1.00e-159	554.00
IUUC-Tre-122097	Trichoderma reesei	47.69	7.00e-83	300.00
IUUC-Tae-125800	Triticum aestivum	89.88	2.00e-177	614.00
IUUC-Uma-129464	Ustilago maydis	44.21	2.00e-75	275.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence