iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111117

Ensembl Protein ID

Solyc01g006190.2.1

UniProt Accession

K4ASI5; K4ASI5_SOLLC

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc01g006190.2	Solyc01g006190.2.1	Solyc01g006190.2.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.32	2.00e-40	163.00	IUUC-Dme-031755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Solanum lycopersicum

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPGGSNYQD IGDSRSAYSD YGIAPESAEF KNSPFRKAAA VIGGKNGVGS NSAVHELLEC 60
PVCMNPMYPP IHQCPNGHTL CVKCKSKVHV CPICRHELGN IRCLALEKIA ESLELPCRYQ 120

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Nucleotide Sequence
(Fasta)

TGTCAATCCA TACCATGAAA CTAGCTGCAG ATGAGGTGTC ATTCTGGATA AGATTTGTTC 60
TCCGTATAAT CGTCCTCTAT GTATATTATC TGCTGTTATA AGATGTACTA GCAATAAAGG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sly:101263446

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006207	Arabidopsis lyrata	72.82	1.00e-136	478.00
IUUC-Ath-007049	Arabidopsis thaliana	72.31	1.00e-136	478.00
IUUC-Bol-016263	Brassica oleracea	72.64	9.00e-138	481.00
IUUC-Bra-016847	Brassica rapa	70.68	1.00e-131	461.00
IUUC-Cin-025674	Ciona intestinalis	32.02	2.00e-40	158.00
IUUC-Csv-026233	Ciona savignyi	32.02	4.00e-40	157.00
IUUC-Cgl-026455	Colletotrichum gloeosporioides	28.57	2.00e-05	42.70
IUUC-Dme-031755	Drosophila melanogaster	36.32	8.00e-42	163.00
IUUC-Mtr-057852	Medicago truncatula	69.58	5.00e-131	459.00
IUUC-Oan-073701	Ornithorhynchus anatinus	25.68	1.00e-11	62.80
IUUC-Pop-099563	Populus trichocarpa	69.35	1.00e-130	457.00
IUUC-Ppe-101760	Prunus persica	72.96	6.00e-140	489.00
IUUC-Stu-112714	Solanum tuberosum	89.35	2.00e-171	593.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence