iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007482

UUCD1 version

UUC-ArT-01563

Ensembl Protein ID

AT4G24210.1

UniProt Accession

Q9STX3; Q8LAQ7; GID2_ARATH

Genbank Protein ID

CAB45056.1; CAB79331.1; AEE84867.1; AAO42210.1; AAO63815.1; AAM65209.1

Protein Name

F-box protein GID2; Protein SLEEPY 1

Genbank Nucleotide ID

AL078637; AL161561; CP002687; BT004192; BT005395; AY087672

Gene Name

GID2; SLY1; At4g24210; T22A6.40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G24210	AT4G24210.1	AT4G24210.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	19717618

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	0.0058	17.6	28	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 99   daglldrlpeeilveilklldkeellraarvcrrwqelasqkalwkt 145
           ++  +++l+e+++ e+lk++d+++l + ++v++ w+++a++++lw+ 
   Q: 28   EEIGFSNLDENLVYEVLKHVDAKTLAMSSCVSKIWHKTAQDERLWEL 74
           4566789*****************************99999***985 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Essential component of the SCF-type E3 ligase complex, SCF(GID2), a complex that positively regulates the gibberellin signaling pathway. Upon gibberellin treatment, the SCF(GID2) complex mediates the ubiquitination and subsequent degradation of DELLA proteins (GAI, RGA and RGL2), some repressors of the gibberellin pathway, leading to activate the pathway.

Protein Sequence
(Fasta)

MKRSTTDSDL AGDAHNETNK KMKSTEEEEI GFSNLDENLV YEVLKHVDAK TLAMSSCVSK 60
IWHKTAQDER LWELICTRHW TNIGCGQNQL RSVVLALGGF RRLHSLYLWP LSKPNPRARF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTGGTACA TTCAATGAAC ACTCTTTTTA ATAGTTGAAA ATAAACATTT GGGAAGAACT 60
AAGAAGAAAC AACATTATAA GATGGGCTTG GGCTTTTTGT TGTATTGTTT TTTATGTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0939--Gibberellin signaling pathway
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR001810--F-box_dom

Pfam

PF00646--F-box

Gene Ontology

GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0009740--P:gibberellic acid mediated signaling pathway
GO:0016567--P:protein ubiquitination
GO:0010162--P:seed dormancy process
GO:0009845--P:seed germination

KEGG

ath:AT4G24210

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002597	Amborella trichopoda	59.84	1.00e-35	142.00
IUUC-Apl-003324	Anas platyrhynchos	28.89	3.70e-02	32.30
IUUC-Aly-006435	Arabidopsis lyrata	94.74	1.00e-81	293.00
IUUC-Afl-008386	Aspergillus flavus	34.78	8.80e-02	30.80
IUUC-Bdi-014906	Brachypodium distachyon	45.60	1.00e-28	119.00
IUUC-Bol-016273	Brassica oleracea	77.33	7.00e-58	214.00
IUUC-Bra-016627	Brassica rapa	78.00	6.00e-59	218.00
IUUC-Ete-032914	Echinops telfairi	38.60	1.00e-03	35.80
IUUC-Eeu-035144	Erinaceus europaeus	31.11	8.10e-02	30.40
IUUC-Gma-043301	Glycine max	55.43	2.00e-47	180.00
IUUC-Hsa-046251	Homo sapiens	37.50	2.00e-05	41.60
IUUC-Hvu-047070	Hordeum vulgare	45.00	1.00e-24	105.00
IUUC-Mtr-057791	Medicago truncatula	55.80	1.00e-48	184.00
IUUC-Mac-064781	Musa acuminata	54.24	9.00e-34	135.00
IUUC-Opr-070849	Ochotona princeps	37.50	3.00e-05	41.60
IUUC-Oan-072882	Ornithorhynchus anatinus	33.71	3.00e-05	40.40
IUUC-Obr-076578	Oryza brachyantha	44.96	2.00e-30	125.00
IUUC-Ogl-077389	Oryza glaberrima	46.61	1.00e-21	95.50
IUUC-Oin-079212	Oryza indica	46.61	1.00e-21	95.50
IUUC-Pma-094686	Petromyzon marinus	31.58	2.00e-03	35.00
IUUC-Pop-098990	Populus trichocarpa	57.79	1.00e-48	185.00
IUUC-Ppe-102068	Prunus persica	59.29	2.00e-44	170.00
IUUC-Smo-108701	Selaginella moellendorffii	45.76	1.00e-20	91.70
IUUC-Sit-110635	Setaria italica	50.00	7.00e-21	93.20
IUUC-Sly-111686	Solanum lycopersicum	49.22	3.00e-24	103.00
IUUC-Stu-111934	Solanum tuberosum	50.75	1.00e-23	102.00
IUUC-Sbi-113872	Sorghum bicolor	50.00	1.00e-17	82.40
IUUC-Tca-121336	Theobroma cacao	64.81	2.00e-56	210.00
IUUC-Vvi-131285	Vitis vinifera	59.72	2.00e-44	171.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence