iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067928

Ensembl Protein ID

ENSMLUP00000004914.2

UniProt Accession

G1P4M3; G1P4M3_MYOLU

Genbank Protein ID

ENSMLUP00000004914

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02020856

Gene Name

PHIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000005375.2	ENSMLUT00000005385.2	ENSMLUP00000004914.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-35	117.8	145	182
UBD/Beta-Prp	3.80e-52	177.4	246	505

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 145  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 182
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkl.....lrsl.sgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvls 99
           +k++l ++++dgti  w ++ g+l      +++ +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+v s
   Q: 246  SKRYLSSTGADGTICFWLWDAGTLkinprPAKFtERPRPGVQMICssFSAGGMFLATGSTDHIIRVYffGSGQPEKISELEFHTDKVDS 334
           789***********999999999988988555547777888765522777888**************777779999************* PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
           ++fs +++++vsGs+d t+r+w+ + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+l+
   Q: 335  IQFSNTSNRFVSGSRDGTARIWQFKRREWKSIlldmatrpagqnlqgiEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLI 423
           ******************************99***************888899999********************************* PP
   S: 173  rtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           + l g h+d v  l+   fd+  + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 424  HVLMG-HEDEVFVLEphpFDP--RVLFSAGHDGNVIVWDLARGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 505
           ****9.*********999999..89******************999998875544445566667777999999999999988887 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

RDVLSPQLLP RRTDWTGKEH PRTYQNLVKY YRHLAPDHLL QICHRLGPLL EQEIPQSVPG 60
VQTLLGAGRQ SLLRTNKSCK HVVWKGSALA ALHCGRPPES PINYGSPPSI ADTLFSRRLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGACGTCC TCTCCCCGCA GCTGCTGCCT CGACGCACCG ACTGGACCGG GAAGGAGCAT 60
CCCAGGACCT ACCAGAATCT GGTGAGACAT TCACGTCGCG GAGCAAAGAA ACTTTTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0022604--P:regulation of cell morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002299	Ailuropoda melanoleuca	95.12	0.00e+00	3199.00
IUUC-Apl-003700	Anas platyrhynchos	85.59	0.00e+00	2848.00
IUUC-Aly-006406	Arabidopsis lyrata	31.92	2.00e-65	244.00
IUUC-Ath-006801	Arabidopsis thaliana	31.76	2.00e-66	248.00
IUUC-Bta-013125	Bos taurus	93.98	0.00e+00	3097.00
IUUC-Bdi-014797	Brachypodium distachyon	30.83	7.00e-56	213.00
IUUC-Bol-015737	Brassica oleracea	32.40	2.00e-69	258.00
IUUC-Bra-017961	Brassica rapa	32.72	6.00e-69	256.00
IUUC-Cja-018868	Callithrix jacchus	92.55	0.00e+00	3206.00
IUUC-Cfa-021179	Canis familiaris	94.44	0.00e+00	3091.00
IUUC-Cpo-022077	Cavia porcellus	89.91	0.00e+00	3064.00
IUUC-Csa-023618	Chlorocebus sabaeus	97.71	0.00e+00	1683.00
IUUC-Cho-024794	Choloepus hoffmanni	90.32	0.00e+00	871.00
IUUC-Dre-028029	Danio rerio	79.97	0.00e+00	1286.00
IUUC-Dno-030048	Dasypus novemcinctus	94.23	0.00e+00	3160.00
IUUC-Dor-030195	Dipodomys ordii	89.19	0.00e+00	1448.00
IUUC-Ete-032748	Echinops telfairi	81.61	0.00e+00	1123.00
IUUC-Eca-034274	Equus caballus	95.34	0.00e+00	3159.00
IUUC-Eeu-034688	Erinaceus europaeus	93.87	0.00e+00	1293.00
IUUC-Fca-035451	Felis catus	94.05	0.00e+00	3039.00
IUUC-Fal-037465	Ficedula albicollis	85.24	0.00e+00	2860.00
IUUC-Gmo-039451	Gadus morhua	68.58	0.00e+00	723.00
IUUC-Gga-040798	Gallus gallus	85.01	0.00e+00	2888.00
IUUC-Gma-043340	Glycine max	34.85	5.00e-67	250.00
IUUC-Ggo-045347	Gorilla gorilla	92.70	0.00e+00	3207.00
IUUC-Hsa-046757	Homo sapiens	97.71	0.00e+00	1650.00
IUUC-Hvu-047706	Hordeum vulgare	31.84	1.00e-37	150.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	90.07	0.00e+00	1155.00
IUUC-Lch-050646	Latimeria chalumnae	77.14	0.00e+00	2684.00
IUUC-Laf-054140	Loxodonta africana	94.15	0.00e+00	3196.00
IUUC-Mcc-055061	Macaca mulatta	98.19	0.00e+00	1690.00
IUUC-Mmr-060837	Microcebus murinus	95.32	0.00e+00	3188.00
IUUC-Mdo-061903	Monodelphis domestica	88.94	0.00e+00	3076.00
IUUC-Mmu-063772	Mus musculus	92.22	0.00e+00	3153.00
IUUC-Mac-065343	Musa acuminata	30.13	3.00e-68	254.00
IUUC-Mpu-066359	Mustela putorius furo	94.55	0.00e+00	2937.00
IUUC-Nle-070094	Nomascus leucogenys	97.83	0.00e+00	1654.00
IUUC-Opr-070971	Ochotona princeps	74.06	0.00e+00	946.00
IUUC-Ont-072221	Oreochromis niloticus	76.10	0.00e+00	1269.00
IUUC-Oan-073185	Ornithorhynchus anatinus	86.02	0.00e+00	2873.00
IUUC-Ocu-074033	Oryctolagus cuniculus	93.43	0.00e+00	2828.00
IUUC-Ogl-077493	Oryza glaberrima	24.77	5.00e-29	124.00
IUUC-Ogu-078641	Oryza glumaepatula	24.28	1.00e-29	125.00
IUUC-Oin-079669	Oryza indica	31.13	3.00e-52	199.00
IUUC-Olo-080755	Oryza longistaminata	31.65	4.00e-54	207.00
IUUC-Oni-082991	Oryza nivara	27.78	2.00e-39	159.00
IUUC-Oga-088578	Otolemur garnettii	94.15	0.00e+00	3129.00
IUUC-Oar-090247	Ovis aries	94.20	0.00e+00	3096.00
IUUC-Ptr-091266	Pan troglodytes	97.81	0.00e+00	1628.00
IUUC-Pan-092734	Papio anubis	97.71	0.00e+00	1682.00
IUUC-Pfo-096191	Poecilia formosa	73.17	0.00e+00	2030.00
IUUC-Pab-098402	Pongo abelii	97.71	0.00e+00	1651.00
IUUC-Pca-101128	Procavia capensis	91.40	0.00e+00	1461.00
IUUC-Ppe-101849	Prunus persica	31.15	2.00e-68	254.00
IUUC-Pva-103058	Pteropus vampyrus	94.10	0.00e+00	1573.00
IUUC-Rno-106013	Rattus norvegicus	91.53	0.00e+00	3088.00
IUUC-Sha-107496	Sarcophilus harrisii	89.26	0.00e+00	3065.00
IUUC-Sar-113520	Sorex araneus	82.41	0.00e+00	1673.00
IUUC-Ssc-115461	Sus scrofa	90.96	0.00e+00	3039.00
IUUC-Tgu-116821	Taeniopygia guttata	84.79	0.00e+00	2850.00
IUUC-Tsy-119132	Tarsius syrichta	82.39	0.00e+00	2551.00
IUUC-Tae-122854	Triticum aestivum	30.33	4.00e-64	240.00
IUUC-Tbe-127479	Tupaia belangeri	89.57	0.00e+00	1422.00
IUUC-Ttr-128427	Tursiops truncatus	90.34	0.00e+00	3018.00
IUUC-Vpa-130160	Vicugna pacos	91.33	0.00e+00	3022.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence