iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppa-095932

Ensembl Protein ID

PP1S84_170V6.1

UniProt Accession

A9RGJ1; A9RGJ1_PHYPA

Genbank Protein ID

EDQ81925.1

Protein Name

Predicted protein

Genbank Nucleotide ID

DS544897

Gene Name

PHYPADRAFT_113939

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S84_170V6	PP1S84_170V6.1	PP1S84_170V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-30	103.4	281	311
E3 adaptor/Cullin RING/APC_C/CDC20	6.50e-132	440.2	147	452
UBD/Beta-Prp	1.20e-40	140.3	251	467

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+ +v++l++ ++   l+sG++D+ +++WD
   Q: 281  GHEQEVCGLKWsPSgQQLASGGNDNLLHIWD 311
           8***********66699************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladleekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltgh 95
           pe+ ldap+l dd+ylnLldWss+nvla+aLg++vylw+a+t+++++l+ ++e+  +tsvsw ++g+++avG ++++v+++D ++ +++rtl gh
   Q: 147  PERTLDAPDLLDDYYLNLLDWSSNNVLAIALGMTVYLWDATTSSIEELMTVDEEGPITSVSWAPDGQYIAVGLNNSTVQLWDSTSLRQLRTLRGH 241
           6799******************************************************************************************* PP
   S: 96   sarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plkkfkehkaavkaia 186
           sarvgaL+Wn  +l++G+rd +il +dvr++++ + +l++h+qevCGlkw+ ++++LasGGnDn +++wd++  +     l++ ++h+aavka+a
   Q: 242  SARVGALAWNGPTLATGGRDSTILNHDVRIRNHVIGKLTGHEQEVCGLKWSPSGQQLASGGNDNLLHIWDSAAASnsssYLHRLDDHQAAVKALA 336
           **********************************************************************987664555788999********** PP
   S: 187  wsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgea 281
           w+P+q++lLasGGGtaDrcikfwnt tg ++++idt+sqvc l wsk++ke++s+hGf++n++ lwkyps+ k+ae +gh++Rvl+la spdg +
   Q: 337  WCPFQSNLLASGGGTADRCIKFWNTHTGVCVNSIDTQSQVCALQWSKHEKEILSSHGFSQNQLCLWKYPSMVKMAEFTGHTSRVLHLAQSPDGYT 431
           *********************************************************************************************** PP
   S: 282  ivtaagDetlrfwklfdkkka 302
           +++aagDetlrfw++f + ++
   Q: 432  VASAAGDETLRFWQVFGTPET 452
           ****************87765 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkl.lrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkghedsvlslsfsp.sgdkl 109
           +++ latg+rd+ti  +dv+  +  + +l ghe+ev  +k+sp+g+ l++g++D+++++wd      +++++h l  h++ v +l+++p +++ l
   Q: 251  NGPTLATGGRDSTILNHDVRIRNHvIGKLTGHEQEVCGLKWSPSGQQLASGGNDNLLHIWDSAaasnSSSYLHRLDDHQAAVKALAWCPfQSNLL 345
           8999***************9877669**********************************7666666999*******************88899* PP
   S: 110  vsG..shdrtirvwdletgqcleetlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsl 200
           +sG  ++dr i+ w+++tg c+++++++ +  v+ +++++ +   l   G+  +++ lW+ +++  + ++tg ht++v +l+ +++g  ++s++ 
   Q: 346  ASGggTADRCIKFWNTHTGVCVNSIDTQSQ--VCALQWSKHEkeILSSHGFSQNQLCLWKYPSMVKMAEFTG-HTSRVLHLAQSPDGYTVASAAG 437
           *963368****************9999998..6666666666304445599********************9.********************** PP
   S: 201  dgtvklwdlq.tgecvrtlnghtdnvksvr 229
           d t+++w++  t e+ +t +  t+ v s  
   Q: 438  DETLRFWQVFgTPETKQTSQKRTKEVGSAL 467
           ********9777777777777776666655 PP

Organism

Physcomitrella patens

Protein Sequence
(Fasta)

MATMAKAFQT PTKSASARWD RDPLRERMSP EPVVTKKTPK TKTPGRSTDR FITDRSAMDF 60
EVANYLLSKE NSSSEATSPM KMAYRKHLAE NLLNDNCQKQ SRILAFKSKP PPPSEGFQNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTACCA TGGCCAAGGC GTTTCAGACC CCGACCAAGA GTGCGAGTGC ACGATGGGAC 60
CGGGATCCTC TGCGGGAGCG CATGAGCCCT GAGCCCGTTG TGACTAAGAA GACTCCCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR023302--Pept_S9A_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

ppp:PHYPADRAFT_113939

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002628	Amborella trichopoda	60.57	3.00e-145	507.00
IUUC-Eeu-035059	Erinaceus europaeus	45.00	7.00e-95	340.00
IUUC-Gma-043985	Glycine max	67.32	1.00e-148	519.00
IUUC-Lpe-050954	Leersia perrieri	67.95	3.00e-151	527.00
IUUC-Mtr-057725	Medicago truncatula	62.82	2.00e-144	504.00
IUUC-Ogl-077254	Oryza glaberrima	67.46	5.00e-152	530.00
IUUC-Olo-080449	Oryza longistaminata	66.82	3.00e-153	533.00
IUUC-Opu-084007	Oryza punctata	67.22	2.00e-151	528.00
IUUC-Osa-086094	Oryza sativa	67.22	1.00e-151	528.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence