iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006803

Ensembl Protein ID

AT5G15380.1

UniProt Accession

Q9LXE5; Q6QPM0; Q9LXE6; DRM1L_ARATH

Genbank Protein ID

CAB89347.1; CAB89348.1; AED92154.1; AAS45433.1

Protein Name

DNA (cytosine-5)-methyltransferase DRM1; Protein DOMAINS REARRANGED METHYLASE 1

Genbank Nucleotide ID

AL353993; AL353993; CP002688; AY530748

Gene Name

DRM1; At5g15380/At5g15370; F8M21.270/F8M21.260

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G15380	AT5G15380.1	AT5G15380.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.40e-11	45.0	111	147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + +++ +++MGF++e++++a++++ + ++ + ++ Ll
   Q: 111  SKVINHFIAMGFPEEHVIKAMQEHgDEDVGEITNALL 147
           6789*************************99999887 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Involved in de novo DNA methylation. Controls asymmetric and CpNpG methylation. Required for FWA gene silencing but not for the maintenance of SUP gene silencing. Functionally redundant to CMT3 to maintain non-CpG methylation. Involved in RNA-directed DNA methylation.

Protein Sequence
(Fasta)

MVMSHIFLIS QIQEVEHGDS DDVNWNTDDD ELAIDNFQFS PSPVHISATS PNSIQNRISD 60
ETVASFVEMG FSTQMIARAI EETAGANMEP MMILETLFNY SASTEASSSK SKVINHFIAM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAATGT CACATATCTT TCTTATCTCT CAGATACAAG AAGTTCTGGA AATGAATATG 60
ATAAGAGTTT GATTTTTCTT TGTGTGTGCA ATGTTTCGTT AGGTGGAACA TGGTGATAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase

Interpro

IPR029063--SAM-dependent_MTases
IPR030380--SAM_MeTfrase_DRM
IPR015940--UBA

PROSITE

PS51680--SAM_MT_DRM
PS50030--UBA

Pfam

PF00145--DNA_methylase

Gene Ontology

GO:0005634--C:nucleus
GO:0003886--F:DNA (cytosine-5-)-methyltransferase activity
GO:0003677--F:DNA binding
GO:0050832--P:defense response to fungus
GO:0006306--P:DNA methylation
GO:0016458--P:gene silencing
GO:0051567--P:histone H3-K9 methylation
GO:0006346--P:methylation-dependent chromatin silencing

KEGG

ath:AT5G15380

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006325	Arabidopsis lyrata	84.93	0.00e+00	941.00
IUUC-Bol-016155	Brassica oleracea	66.61	0.00e+00	741.00
IUUC-Bra-017325	Brassica rapa	69.33	0.00e+00	744.00
IUUC-Kpa-049108	Komagataella pastoris	34.62	1.30e-01	31.20
IUUC-Lch-050450	Latimeria chalumnae	32.61	2.40e-02	33.10
IUUC-Oni-082521	Oryza nivara	68.21	8.00e-114	404.00
IUUC-Psi-093796	Pelodiscus sinensis	27.59	1.50e-01	30.40
IUUC-Pop-099706	Populus trichocarpa	57.07	9.00e-179	619.00
IUUC-Ppe-101607	Prunus persica	58.33	6.00e-153	533.00
IUUC-Sre-115063	Sporisorium reilianum	40.00	1.00e+00	28.90
IUUC-Tca-121673	Theobroma cacao	54.88	0.00e+00	656.00
IUUC-Uma-129545	Ustilago maydis	40.00	6.00e-01	29.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence