iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001662

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01011461

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000016854.1	ENSAMET00000018551.1	ENSAMEP00000017826.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.30e-132	443.0	11	419

Active Site

Position(s)	Description	Evidence
171	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 12   aqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitel 100
             +++   +vl+vGag  G+EllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n+ a+++si+++
   Q: 11   LADAVAGGRVLVVGAG--GSELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIIAYHDSIMNP 97
           56788999********..7********************************************************************** PP
   S: 101  eeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiew 189
           +++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+w
   Q: 98   DYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVW 186
           ***************************************************************************************** PP
   S: 190  a.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv.. 274
           a +lfn+l++ee++++ev++  d++++e++++++++e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++  
   Q: 187  AkYLFNQLFGEEDADQEVSP--DRADPEASWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWrk 273
           ********************..799**************************************************************** PP
   S: 275  ................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanl 342
                           +  + ++++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aanl
   Q: 274  rkppvpldwaevqsqgEETNASDQQNEPQLGLKDQQVLDVKSYaclfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAANL 359
           ***************999999********************************************...68******************* PP
   S: 343  raeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           r++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 360  RMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 419
           *********.***********************************************9965 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MALSRGLPRE LADAVAGGRV LVVGAGGSEL LKNLVLTGFS HIDLIDLDTI DVSNLNRQFL 60
FQKKHVGRSK AQVAKESVLQ FYPKANIIAY HDSIMNPDYN VEFFRQFILV MNALDNRAAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGT CGCGGGGACT ACCCCGGGAG CTGGCCGACG CCGTGGCCGG GGGCCGGGTG 60
CTGGTGGTGG GCGCGGGCGG CAGCGAGCTC CTCAAGAACC TCGTGCTCAC CGGCTTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	37.46	7.00e-104	371.00
IUUC-Atr-002636	Amborella trichopoda	39.84	2.00e-107	383.00
IUUC-Apl-003369	Anas platyrhynchos	89.24	0.00e+00	1023.00
IUUC-Aca-004490	Anolis carolinensis	82.64	0.00e+00	912.00
IUUC-Aly-006359	Arabidopsis lyrata	41.39	3.00e-101	362.00
IUUC-Ath-007667	Arabidopsis thaliana	41.58	1.00e-104	374.00
IUUC-Ago-007844	Ashbya gossypii	36.17	2.00e-79	290.00
IUUC-Acl-008270	Aspergillus clavatus	41.67	3.00e-100	358.00
IUUC-Afl-008674	Aspergillus flavus	42.70	3.00e-107	382.00
IUUC-Afu-008883	Aspergillus fumigatus	41.08	2.00e-101	363.00
IUUC-Ani-009500	Aspergillus nidulans	44.38	3.00e-111	395.00
IUUC-Ang-009535	Aspergillus niger	43.08	4.00e-106	378.00
IUUC-Aor-010223	Aspergillus oryzae	43.51	1.00e-109	390.00
IUUC-Ate-010282	Aspergillus terreus	43.45	8.00e-86	311.00
IUUC-Ame-011736	Astyanax mexicanus	77.44	0.00e+00	979.00
IUUC-Bgr-012166	Blumeria graminis	41.89	1.00e-94	340.00
IUUC-Bta-012589	Bos taurus	97.66	0.00e+00	1255.00
IUUC-Bci-013802	Botrytis cinerea	41.78	8.00e-97	347.00
IUUC-Bdi-014697	Brachypodium distachyon	41.21	1.00e-107	383.00
IUUC-Bol-016315	Brassica oleracea	39.08	2.00e-107	382.00
IUUC-Bra-017009	Brassica rapa	39.85	1.00e-107	383.00
IUUC-Cel-018708	Caenorhabditis elegans	45.56	6.00e-127	447.00
IUUC-Cja-019120	Callithrix jacchus	97.50	0.00e+00	1201.00
IUUC-Cfa-021061	Canis familiaris	98.75	0.00e+00	1265.00
IUUC-Cpo-021842	Cavia porcellus	96.41	0.00e+00	1192.00
IUUC-Csa-024104	Chlorocebus sabaeus	97.82	0.00e+00	1177.00
IUUC-Cho-024332	Choloepus hoffmanni	85.18	0.00e+00	868.00
IUUC-Cin-025363	Ciona intestinalis	60.75	0.00e+00	660.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	41.75	2.00e-94	339.00
IUUC-Cne-026888	Cryptococcus neoformans	52.96	1.00e-68	254.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.33	6.00e-55	209.00
IUUC-Dre-028420	Danio rerio	74.21	0.00e+00	904.00
IUUC-Dno-030041	Dasypus novemcinctus	97.82	0.00e+00	1215.00
IUUC-Dor-031039	Dipodomys ordii	81.13	0.00e+00	647.00
IUUC-Dse-031504	Dothistroma septosporum	37.21	9.00e-90	324.00
IUUC-Dme-031771	Drosophila melanogaster	48.85	1.00e-143	503.00
IUUC-Ete-033037	Echinops telfairi	90.95	0.00e+00	1080.00
IUUC-Eca-033774	Equus caballus	98.82	0.00e+00	1213.00
IUUC-Eeu-035074	Erinaceus europaeus	97.75	0.00e+00	974.00
IUUC-Fca-036508	Felis catus	99.16	0.00e+00	1216.00
IUUC-Fal-036813	Ficedula albicollis	86.85	0.00e+00	1017.00
IUUC-Fox-038056	Fusarium oxysporum	43.02	4.00e-102	365.00
IUUC-Fso-038223	Fusarium solani	42.33	2.00e-100	359.00
IUUC-Gmo-038526	Gadus morhua	74.25	0.00e+00	887.00
IUUC-Ggr-039767	Gaeumannomyces graminis	42.39	1.00e-95	343.00
IUUC-Gga-040981	Gallus gallus	87.36	0.00e+00	1033.00
IUUC-Gac-041437	Gasterosteus aculeatus	75.68	0.00e+00	911.00
IUUC-Gma-044072	Glycine max	37.27	2.00e-110	393.00
IUUC-Ggo-045358	Gorilla gorilla	94.43	0.00e+00	1121.00
IUUC-Hsa-046068	Homo sapiens	97.66	0.00e+00	1170.00
IUUC-Hvu-047646	Hordeum vulgare	37.62	2.00e-103	370.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.88	0.00e+00	1206.00
IUUC-Lch-049565	Latimeria chalumnae	80.75	0.00e+00	1019.00
IUUC-Lpe-050884	Leersia perrieri	40.26	2.00e-104	373.00
IUUC-Loc-052493	Lepisosteus oculatus	80.51	0.00e+00	1002.00
IUUC-Lma-053117	Leptosphaeria maculans	43.57	2.00e-96	346.00
IUUC-Laf-054518	Loxodonta africana	94.23	0.00e+00	1189.00
IUUC-Mcc-055334	Macaca mulatta	97.35	0.00e+00	1167.00
IUUC-Mor-057137	Magnaporthe oryzae	43.54	2.00e-90	326.00
IUUC-Mpo-057449	Magnaporthe poae	40.73	5.00e-98	352.00
IUUC-Mtr-058045	Medicago truncatula	39.75	1.00e-113	403.00
IUUC-Mla-058864	Melampsora laricipopulina	45.09	1.00e-91	330.00
IUUC-Mga-059422	Meleagris gallopavo	83.06	0.00e+00	928.00
IUUC-Mvi-060536	Microbotryum violaceum	41.51	2.00e-82	300.00
IUUC-Mmr-061161	Microcebus murinus	95.87	0.00e+00	1197.00
IUUC-Mdo-061802	Monodelphis domestica	92.06	0.00e+00	1132.00
IUUC-Mmu-064357	Mus musculus	93.29	0.00e+00	1180.00
IUUC-Mac-065475	Musa acuminata	38.38	2.00e-105	376.00
IUUC-Mpu-066895	Mustela putorius furo	98.91	0.00e+00	1266.00
IUUC-Mlu-067862	Myotis lucifugus	97.50	0.00e+00	1251.00
IUUC-Nfi-068385	Neosartorya fischeri	43.05	2.00e-104	373.00
IUUC-Ncr-068885	Neurospora crassa	41.05	5.00e-103	368.00
IUUC-Nle-069524	Nomascus leucogenys	96.88	0.00e+00	1153.00
IUUC-Opr-071038	Ochotona princeps	96.57	0.00e+00	1231.00
IUUC-Ont-071719	Oreochromis niloticus	75.67	0.00e+00	970.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.42	0.00e+00	994.00
IUUC-Ocu-074080	Oryctolagus cuniculus	97.04	0.00e+00	1197.00
IUUC-Oba-075936	Oryza barthii	37.44	3.00e-104	372.00
IUUC-Obr-076841	Oryza brachyantha	37.85	2.00e-106	380.00
IUUC-Ogl-077686	Oryza glaberrima	37.50	1.00e-105	377.00
IUUC-Ogu-078597	Oryza glumaepatula	36.57	3.00e-101	362.00
IUUC-Oin-079791	Oryza indica	37.44	3.00e-104	372.00
IUUC-Olo-081009	Oryza longistaminata	39.19	4.00e-104	372.00
IUUC-Ome-081327	Oryza meridionalis	35.16	8.00e-99	354.00
IUUC-Oni-082334	Oryza nivara	36.74	1.00e-101	363.00
IUUC-Opu-083447	Oryza punctata	39.38	4.00e-105	375.00
IUUC-Oru-084977	Oryza rufipogon	39.19	4.00e-104	372.00
IUUC-Osa-086160	Oryza sativa	43.00	3.00e-91	328.00
IUUC-Ola-087415	Oryzias latipes	75.28	0.00e+00	927.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.67	7.00e-97	347.00
IUUC-Oga-088434	Otolemur garnettii	97.04	0.00e+00	1199.00
IUUC-Oar-089872	Ovis aries	98.49	0.00e+00	1219.00
IUUC-Ptr-091212	Pan troglodytes	97.66	0.00e+00	1170.00
IUUC-Pan-092708	Papio anubis	97.30	2.00e-130	459.00
IUUC-Psi-093703	Pelodiscus sinensis	90.76	0.00e+00	1050.00
IUUC-Pno-094953	Phaeosphaeria nodorum	46.06	5.00e-101	361.00
IUUC-Ppa-095963	Physcomitrella patens	43.56	6.00e-104	371.00
IUUC-Pfo-097515	Poecilia formosa	75.08	0.00e+00	922.00
IUUC-Pab-097951	Pongo abelii	97.98	0.00e+00	1022.00
IUUC-Pop-099703	Populus trichocarpa	36.17	2.00e-92	333.00
IUUC-Pca-100426	Procavia capensis	94.23	0.00e+00	1204.00
IUUC-Ppe-101152	Prunus persica	38.83	9.00e-109	387.00
IUUC-Pva-102792	Pteropus vampyrus	94.09	0.00e+00	1165.00
IUUC-Pgr-103592	Puccinia graminis	42.94	5.00e-96	345.00
IUUC-Ptt-103805	Puccinia triticina	41.09	4.00e-82	299.00
IUUC-Pte-104215	Pyrenophora teres	38.60	5.00e-108	384.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	44.99	1.00e-105	377.00
IUUC-Rno-106117	Rattus norvegicus	93.76	0.00e+00	1186.00
IUUC-Sce-106177	Saccharomyces cerevisiae	33.28	6.00e-73	268.00
IUUC-Sha-107006	Sarcophilus harrisii	92.38	0.00e+00	1136.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.05	1.00e-89	323.00
IUUC-Spo-108020	Schizosaccharomyces pombe	43.91	3.00e-92	332.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	42.69	1.00e-99	357.00
IUUC-Smo-109264	Selaginella moellendorffii	41.11	6.00e-104	371.00
IUUC-Sit-110581	Setaria italica	40.29	5.00e-105	375.00
IUUC-Sly-111870	Solanum lycopersicum	39.24	3.00e-108	385.00
IUUC-Stu-112283	Solanum tuberosum	39.54	7.00e-106	377.00
IUUC-Sar-113432	Sorex araneus	71.96	0.00e+00	794.00
IUUC-Sbi-114075	Sorghum bicolor	39.34	4.00e-104	372.00
IUUC-Sre-114926	Sporisorium reilianum	42.49	1.00e-99	357.00
IUUC-Ssc-116281	Sus scrofa	97.71	2.00e-116	410.00
IUUC-Tgu-117247	Taeniopygia guttata	85.57	0.00e+00	1012.00
IUUC-Tru-118075	Takifugu rubripes	71.20	0.00e+00	887.00
IUUC-Tsy-119398	Tarsius syrichta	81.12	0.00e+00	920.00
IUUC-Tni-120771	Tetraodon nigroviridis	66.26	0.00e+00	797.00
IUUC-Tca-121651	Theobroma cacao	39.56	9.00e-105	374.00
IUUC-Tre-122224	Trichoderma reesei	43.07	5.00e-92	332.00
IUUC-Tvi-122634	Trichoderma virens	42.35	4.00e-92	332.00
IUUC-Tae-125665	Triticum aestivum	40.00	1.00e-101	363.00
IUUC-Tur-126417	Triticum urartu	39.06	3.00e-102	366.00
IUUC-Tme-127016	Tuber melanosporum	43.80	5.00e-92	332.00
IUUC-Tbe-127678	Tupaia belangeri	82.55	3.00e-179	621.00
IUUC-Ttr-128598	Tursiops truncatus	93.76	0.00e+00	1186.00
IUUC-Uma-129612	Ustilago maydis	40.97	1.00e-92	334.00
IUUC-Vda-129811	Verticillium dahliae	39.57	2.00e-97	349.00
IUUC-Vpa-130732	Vicugna pacos	83.93	0.00e+00	1029.00
IUUC-Vvi-130832	Vitis vinifera	39.53	2.00e-102	366.00
IUUC-Xtr-132823	Xenopus tropicalis	76.33	0.00e+00	919.00
IUUC-Xma-133552	Xiphophorus maculatus	74.92	0.00e+00	921.00
IUUC-Yli-134666	Yarrowia lipolytica	37.23	5.00e-71	262.00
IUUC-Zma-135547	Zea mays	37.46	4.00e-103	368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence