iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062285

UUCD1 version

UUC-MoD-00119

Ensembl Protein ID

ENSMODP00000017603.2

UniProt Accession

F6R519; F6R519_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014078.3	ENSMODT00000017929.3	ENSMODP00000017603.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.40e-21	74.7	49	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.40e-10	38.4	148	178

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 49   CDVTLKVGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGHLAI 114
           9*************************************.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+d+a++fi++hF
   Q: 148  PKNCLGVRQFAETMMCAVLYDSANSFIHQHF 178
           68***************************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

RSCGRPWRWE KMVEDGVEEL EDLVHFSVSE LPSRGYGVME EIRRQGKLCD VTLKVGDHKF 60
SAHRIVLAAS IPYFHAMFTN DMMECKQDEI VMQGMDPSAL EALINFAYNG HLAIDQQNVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCAGTTGCG GCCGGCCCTG GAGGTGGGAG AAGATGGTGG AGGACGGAGT GGAGGAGCTG 60
GAAGATCTTG TGCATTTTTC CGTGTCGGAG CTGCCGAGCC GGGGATACGG GGTGATGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	94.30	0.00e+00	1146.00
IUUC-Apl-003270	Anas platyrhynchos	92.66	0.00e+00	1020.00
IUUC-Aca-005395	Anolis carolinensis	93.27	0.00e+00	1112.00
IUUC-Bta-013481	Bos taurus	93.26	0.00e+00	1132.00
IUUC-Cel-018622	Caenorhabditis elegans	44.90	7.00e-142	497.00
IUUC-Cja-019847	Callithrix jacchus	94.95	0.00e+00	1142.00
IUUC-Cfa-020341	Canis familiaris	94.98	0.00e+00	1150.00
IUUC-Cpo-021613	Cavia porcellus	92.55	0.00e+00	1045.00
IUUC-Csa-023611	Chlorocebus sabaeus	94.60	0.00e+00	1142.00
IUUC-Cho-024605	Choloepus hoffmanni	79.26	4.00e-134	471.00
IUUC-Cin-025289	Ciona intestinalis	54.40	0.00e+00	639.00
IUUC-Dre-028248	Danio rerio	85.84	0.00e+00	1036.00
IUUC-Dno-029609	Dasypus novemcinctus	94.26	0.00e+00	1145.00
IUUC-Dor-030541	Dipodomys ordii	94.14	4.00e-146	510.00
IUUC-Dme-032107	Drosophila melanogaster	54.95	0.00e+00	661.00
IUUC-Eca-033507	Equus caballus	95.30	0.00e+00	1071.00
IUUC-Eeu-034750	Erinaceus europaeus	86.25	0.00e+00	944.00
IUUC-Fca-035731	Felis catus	95.64	0.00e+00	1155.00
IUUC-Fal-036959	Ficedula albicollis	93.62	0.00e+00	1078.00
IUUC-Gga-040166	Gallus gallus	95.41	0.00e+00	1129.00
IUUC-Ggo-044853	Gorilla gorilla	94.60	0.00e+00	1141.00
IUUC-Hsa-046437	Homo sapiens	94.25	0.00e+00	1133.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	93.11	0.00e+00	1030.00
IUUC-Lch-050195	Latimeria chalumnae	80.63	0.00e+00	929.00
IUUC-Loc-051787	Lepisosteus oculatus	87.26	0.00e+00	1004.00
IUUC-Laf-053489	Loxodonta africana	94.78	0.00e+00	1144.00
IUUC-Mcc-055250	Macaca mulatta	93.78	0.00e+00	1135.00
IUUC-Meu-056871	Macropus eugenii	92.69	0.00e+00	1077.00
IUUC-Mpo-057526	Magnaporthe poae	34.78	2.00e-06	45.40
IUUC-Mtr-058180	Medicago truncatula	33.62	5.00e-37	149.00
IUUC-Mga-059425	Meleagris gallopavo	95.41	0.00e+00	1125.00
IUUC-Mmr-061394	Microcebus murinus	94.47	0.00e+00	1144.00
IUUC-Mmu-063975	Mus musculus	94.47	0.00e+00	1145.00
IUUC-Mpu-066369	Mustela putorius furo	94.77	0.00e+00	1143.00
IUUC-Mlu-067832	Myotis lucifugus	91.40	0.00e+00	1033.00
IUUC-Nle-069338	Nomascus leucogenys	87.07	0.00e+00	1025.00
IUUC-Opr-071035	Ochotona princeps	83.05	0.00e+00	905.00
IUUC-Ont-071440	Oreochromis niloticus	84.25	0.00e+00	989.00
IUUC-Ola-087275	Oryzias latipes	82.34	0.00e+00	971.00
IUUC-Oga-087921	Otolemur garnettii	95.16	0.00e+00	1154.00
IUUC-Oar-089968	Ovis aries	86.72	0.00e+00	1017.00
IUUC-Ptr-091272	Pan troglodytes	94.60	0.00e+00	1141.00
IUUC-Pan-092629	Papio anubis	94.43	0.00e+00	1137.00
IUUC-Psi-093456	Pelodiscus sinensis	96.43	0.00e+00	1021.00
IUUC-Pma-094509	Petromyzon marinus	69.56	0.00e+00	797.00
IUUC-Pfo-096450	Poecilia formosa	79.82	0.00e+00	970.00
IUUC-Pab-097917	Pongo abelii	94.47	0.00e+00	1145.00
IUUC-Pca-100330	Procavia capensis	94.98	2.00e-171	595.00
IUUC-Pva-103189	Pteropus vampyrus	95.47	0.00e+00	1152.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	34.94	6.00e-07	47.80
IUUC-Sha-107283	Sarcophilus harrisii	99.26	0.00e+00	1132.00
IUUC-Sar-112989	Sorex araneus	93.60	0.00e+00	1050.00
IUUC-Tgu-117146	Taeniopygia guttata	84.60	0.00e+00	939.00
IUUC-Tru-118132	Takifugu rubripes	83.12	0.00e+00	963.00
IUUC-Tsy-119058	Tarsius syrichta	78.60	6.00e-134	470.00
IUUC-Tni-120892	Tetraodon nigroviridis	80.00	0.00e+00	962.00
IUUC-Tbe-127347	Tupaia belangeri	92.68	0.00e+00	1112.00
IUUC-Ttr-128343	Tursiops truncatus	73.82	0.00e+00	771.00
IUUC-Vpa-130796	Vicugna pacos	82.75	0.00e+00	958.00
IUUC-Xtr-132077	Xenopus tropicalis	86.02	0.00e+00	979.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence