iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppa-095785

Ensembl Protein ID

PP1S135_34V6.1

UniProt Accession

A9SXY8; A9SXY8_PHYPA

Genbank Protein ID

EDQ63922.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

DS545024

Gene Name

PHYPADRAFT_216895

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S135_34V6	PP1S135_34V6.1	PP1S135_34V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-36	122.1	50	85
UBD/Beta-Prp	1.90e-75	254.6	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f  s +l+vsG+dD +ikvW+++  ++
   Q: 50   HDGPVRGVHFhkSQPLFVSGGDDYKIKVWNYKMRRC 85
           99*********7559***************876666 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           t +++++++++ + f+p +++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++ + c+ tl gh d+++
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGIIQLWDYRMGTLIDRFDEHDGPVRGVHFHKSQPLFVSGGDDYKIKVWNYKMRRCLFTLLGHLDYIR 97
           67889999*************************************************************************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................k 167
           +++f+ ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++h +++l+vs+slD+tvr+Wd+                           
   Q: 98   TVQFHHESPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHIKEDLVVSASLDQTVRVWDIgalkkksvspaddmmrltqmntdlfgG 191
           ********************************.********************************************999999777666666653 PP
   S: 168  tgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktl 260
            +++++   +gh++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd+ +++ ++t+
   Q: 192  GDSVVKYVLEGHDRGVNWASFHPSLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHVNNVSCVMFHARQDIIVSNSEDKSIRVWDMSKRTGVQTF 286
           33344333555********************************777668********************************************** PP
   S: 261  qlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
            +++++++  ++ +++ n l++g  ds   ++kl++++p
   Q: 287  RREHDRFWILSA-HPEVNLLAAG-HDSGMIVFKLERERP 323
           ************.7776665555.689999999988765 PP

Organism

Physcomitrella patens

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GIIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
KSQPLFVSGG DDYKIKVWNY KMRRCLFTLL GHLDYIRTVQ FHHESPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGACCA AGTTCGAGAC GAAGAGTAAC AGGGTGAAGG GGCTGAGCTT TCACCCGCGG 60
CGGCCATGGA TTCTTGCCAG TCTGCACAGC GGTATTATTC AGCTGTGGGA CTACCGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ppp:PHYPADRAFT_216895

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006020	Arabidopsis lyrata	69.99	0.00e+00	1726.00
IUUC-Ago-007992	Ashbya gossypii	44.59	0.00e+00	1001.00
IUUC-Bci-013781	Botrytis cinerea	49.76	0.00e+00	1202.00
IUUC-Bdi-014549	Brachypodium distachyon	67.92	0.00e+00	1747.00
IUUC-Bra-016978	Brassica rapa	70.02	0.00e+00	1717.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	74.76	0.00e+00	1341.00
IUUC-Dor-030290	Dipodomys ordii	55.36	1.00e-170	593.00
IUUC-Dse-031543	Dothistroma septosporum	48.99	0.00e+00	1129.00
IUUC-Fox-037738	Fusarium oxysporum	50.04	0.00e+00	1210.00
IUUC-Gmo-039602	Gadus morhua	52.83	0.00e+00	1272.00
IUUC-Hvu-047556	Hordeum vulgare	67.67	0.00e+00	1752.00
IUUC-Kpa-049256	Komagataella pastoris	45.77	0.00e+00	1082.00
IUUC-Mac-065398	Musa acuminata	65.85	0.00e+00	1638.00
IUUC-Obr-076429	Oryza brachyantha	76.43	0.00e+00	1376.00
IUUC-Olo-080466	Oryza longistaminata	76.89	0.00e+00	1370.00
IUUC-Ome-081668	Oryza meridionalis	77.46	0.00e+00	1167.00
IUUC-Pno-094839	Phaeosphaeria nodorum	48.62	0.00e+00	1126.00
IUUC-Pfo-097493	Poecilia formosa	56.17	0.00e+00	1379.00
IUUC-Pca-100413	Procavia capensis	62.66	0.00e+00	711.00
IUUC-Ppe-101899	Prunus persica	71.16	0.00e+00	1779.00
IUUC-Pte-104126	Pyrenophora teres	57.50	0.00e+00	1012.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	48.90	0.00e+00	676.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	49.96	0.00e+00	1196.00
IUUC-Smo-109582	Selaginella moellendorffii	80.82	0.00e+00	1476.00
IUUC-Sit-109697	Setaria italica	76.55	0.00e+00	1377.00
IUUC-Sbi-114388	Sorghum bicolor	76.79	0.00e+00	1380.00
IUUC-Sre-115209	Sporisorium reilianum	58.05	0.00e+00	1048.00
IUUC-Tgu-117109	Taeniopygia guttata	49.03	1.00e-122	432.00
IUUC-Tsy-119105	Tarsius syrichta	54.95	0.00e+00	1098.00
IUUC-Tca-120918	Theobroma cacao	79.69	0.00e+00	1425.00
IUUC-Tre-121951	Trichoderma reesei	49.80	0.00e+00	1174.00
IUUC-Tme-127170	Tuber melanosporum	50.37	0.00e+00	1231.00
IUUC-Tbe-127882	Tupaia belangeri	68.06	8.00e-128	451.00
IUUC-Uma-129337	Ustilago maydis	58.64	0.00e+00	1049.00
IUUC-Vvi-130958	Vitis vinifera	70.65	0.00e+00	1791.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence