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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Dme-032079
UUCD1 version UUC-DrM-00634
Ensembl Protein ID FBpp0079650
UniProt Accession Q9VKZ8; Q9VKZ8_DROME
Genbank Protein ID AAF52908.1; ABY20520.1; AGB92856.1
Protein Name LP08774p; Ubiquitin specific protease 14, isoform A; Ubiquitin specific protease 14, isoform B
Genbank Nucleotide ID AE014134; BT031279; AE014134
Gene Name CG5384; Usp14; Dmel_CG5384
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0032216 FBtr0080061 FBpp0079650
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.00e-59 201.5 105 468
ULD/UDP/UBQ/UBQ_Other 2.00e-06 27.6 6 75
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs......gyeqqDaq 93
           Gl+NlgNtCYmN+++QcL ++pelr +l + ++++    +  ++  +++++++++f+++  +k + v+p  ll+al++++++f       +y+qqDa+
   Q: 105  GLTNLGNTCYMNATVQCLNAVPELRTALST-FSNDGT--DTMSTAFSISSAMKSIFAQM--EKGTTVTPIVLLQALHRASPQFAqtgengTYRQQDAN 197
           9****************************9.555544..4478999*************..78888*****************99************* PP
   S: 94   EflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs..sreepfldlslpvpgkeetkkeslqd 189
           E++a +l+ l+++l      pk++e            ++  +k+++s+i++ F+g+++ ++  +e   +   ++ e+fl+ls+ ++++ +     +q+
   Q: 198  ECWAEILKMLQQKL-----RPKNQE-----------PSNTVQKRHSSFIDQFFGGTFEVKMSSEEDPDEPstVTSENFLQLSCFISMDVKY----MQS 275
           **************.....233333...........34568999**************99998776554325999*************985....9** PP
   S: 190  cLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.................... 267
            L+s +ke+ ++     ++e+  ++ +  ++  +++lP +L++++ Rf+++ +++ + k+ k ++fp+ +d  + ct                     
   Q: 276  GLKSKMKEQLVK-----KSETLGRDAKYIRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPelqnklcpmrskfkdledkk 368
           **9999988887.....6899999*****************************************************977777777777777776666 PP
   S: 268  ............peekqke...................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg....st 329
                       +     e                   +  Y L av+ H+G s+ssGHYva+v+++ + W++fdD++V++v  +e+l+ +g    + 
   Q: 369  mevdvvkrnepnE-----EkkdvkyeqfwfdddlgsnnSGYYTLQAVLTHKGrSSSSGHYVAWVRSSGDVWFKFDDDEVSAVATDEILRLSGggdwHC 461
           6666666666540.....044556666666666666669***************************9999*******************988****** PP
   S: 330  aYvlfYk 336
           aYvl+Y 
   Q: 462  AYVLLYA 468
           ******6 PP
   

   ULD/UDP/UBQ/UBQ_Other
   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           v+vk+     +++ vn ++    +K +++ ++g++p++q+ ++kG iL+dd    ++ +kdg +++ll +k+
   Q: 6    VKVKWGRELYTDIVVNTDEEPILFKAQLFALTGVQPDRQKVMCKGGILKDD--QWNLQIKDGAVVLLLGSKE 75
           666666666777778888866668***************************..5667***********9986 PP
   
Organism Drosophila melanogaster
Protein Sequence
(Fasta)
MPAFKVKVKW GRELYTDIVV NTDEEPILFK AQLFALTGVQ PDRQKVMCKG GILKDDQWNL 60
QIKDGAVVLL LGSKESVPEV PATPVKFIED MNEAEAATAM RLPAGLTNLG NTCYMNATVQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032079|DUB,USP;ULD,UBQ_Other|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCGGTGTTT TGCGCATCTC TGCTTCGGCT AGTATGACTT TGAATTTTAC AGAAAGAACA 60
ACTTTTATAA AAGAAAAAAT TAGCCATGCC CGCATTTAAA GGTAGCATTG TGTTTTACAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032079|DUB,USP;ULD,UBQ_Other|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0005875--C:microtubule associated complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0016567--P:protein ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG dme:Dmel_CG5384
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000893 Aegilops tauschii 31.50 2.00e-33 136.00
IUUC-Aml-002053 Ailuropoda melanoleuca 55.58 7.00e-154 536.00
IUUC-Atr-002725 Amborella trichopoda 36.33 3.00e-85 308.00
IUUC-Apl-004031 Anas platyrhynchos 54.89 1.00e-151 528.00
IUUC-Aca-004361 Anolis carolinensis 55.03 1.00e-157 548.00
IUUC-Aly-006176 Arabidopsis lyrata 38.17 5.00e-93 333.00
IUUC-Ath-007658 Arabidopsis thaliana 37.14 3.00e-92 331.00
IUUC-Ago-007796 Ashbya gossypii 31.50 3.00e-59 221.00
IUUC-Acl-008258 Aspergillus clavatus 37.00 7.00e-58 217.00
IUUC-Afl-008732 Aspergillus flavus 33.46 3.00e-71 262.00
IUUC-Afu-008755 Aspergillus fumigatus 37.33 9.00e-60 223.00
IUUC-Ani-009148 Aspergillus nidulans 32.98 9.00e-75 273.00
IUUC-Ang-009878 Aspergillus niger 33.09 1.00e-68 253.00
IUUC-Aor-010239 Aspergillus oryzae 33.46 3.00e-71 262.00
IUUC-Ate-010243 Aspergillus terreus 32.52 2.00e-68 253.00
IUUC-Ame-011327 Astyanax mexicanus 38.03 7.00e-77 280.00
IUUC-Bgr-012231 Blumeria graminis 31.51 1.00e-70 259.00
IUUC-Bta-012553 Bos taurus 55.14 2.00e-155 541.00
IUUC-Bci-013606 Botrytis cinerea 38.50 2.00e-66 245.00
IUUC-Bdi-014567 Brachypodium distachyon 39.59 2.00e-97 348.00
IUUC-Bol-015565 Brassica oleracea 38.76 4.00e-95 341.00
IUUC-Bra-017297 Brassica rapa 38.40 7.00e-94 337.00
IUUC-Cel-018140 Caenorhabditis elegans 37.68 6.00e-85 306.00
IUUC-Cja-019516 Callithrix jacchus 54.75 4.00e-155 540.00
IUUC-Cfa-020808 Canis familiaris 55.56 2.00e-156 545.00
IUUC-Cpo-021688 Cavia porcellus 55.46 1.00e-152 531.00
IUUC-Cre-022663 Chlamydomonas reinhardtii 36.55 5.00e-72 264.00
IUUC-Csa-023429 Chlorocebus sabaeus 55.35 4.00e-154 536.00
IUUC-Cho-024347 Choloepus hoffmanni 55.35 4.00e-155 540.00
IUUC-Cin-025198 Ciona intestinalis 49.59 4.00e-131 460.00
IUUC-Csv-026007 Ciona savignyi 48.28 4.00e-133 467.00
IUUC-Cgl-026757 Colletotrichum gloeosporioides 37.33 1.00e-58 220.00
IUUC-Cne-026963 Cryptococcus neoformans 33.26 6.00e-65 240.00
IUUC-Cme-027240 Cyanidioschyzon merolae 31.31 1.00e-58 219.00
IUUC-Dre-027647 Danio rerio 55.69 2.00e-159 555.00
IUUC-Dno-029967 Dasypus novemcinctus 55.12 6.00e-154 536.00
IUUC-Dor-030886 Dipodomys ordii 50.69 1.00e-117 416.00
IUUC-Dse-031466 Dothistroma septosporum 35.36 9.00e-55 207.00
IUUC-Ete-032351 Echinops telfairi 51.99 1.00e-141 495.00
IUUC-Eca-033461 Equus caballus 55.14 3.00e-159 553.00
IUUC-Eeu-035220 Erinaceus europaeus 42.47 2.00e-100 358.00
IUUC-Fca-036210 Felis catus 55.35 3.00e-156 544.00
IUUC-Fal-037528 Ficedula albicollis 54.94 3.00e-151 527.00
IUUC-Fox-037805 Fusarium oxysporum 38.51 2.00e-67 249.00
IUUC-Fso-038177 Fusarium solani 38.72 2.00e-65 242.00
IUUC-Gmo-038953 Gadus morhua 53.80 1.00e-145 509.00
IUUC-Ggr-039972 Gaeumannomyces graminis 36.19 7.00e-59 220.00
IUUC-Gga-040462 Gallus gallus 55.17 4.00e-154 536.00
IUUC-Gac-041312 Gasterosteus aculeatus 55.97 2.00e-153 535.00
IUUC-Gma-043255 Glycine max 37.73 8.00e-92 330.00
IUUC-Ggo-045458 Gorilla gorilla 46.73 5.00e-119 420.00
IUUC-Hsa-045706 Homo sapiens 55.35 4.00e-154 536.00
IUUC-Hvu-047821 Hordeum vulgare 41.18 1.00e-48 185.00
IUUC-Itr-048654 Ictidomys tridecemlineatus 55.35 5.00e-158 550.00
IUUC-Lch-050464 Latimeria chalumnae 55.81 3.00e-155 540.00
IUUC-Lpe-051419 Leersia perrieri 39.29 2.00e-92 331.00
IUUC-Loc-052732 Lepisosteus oculatus 54.58 3.00e-155 540.00
IUUC-Lma-053177 Leptosphaeria maculans 36.89 7.00e-66 244.00
IUUC-Laf-053822 Loxodonta africana 55.35 6.00e-155 539.00
IUUC-Mcc-055893 Macaca mulatta 55.35 4.00e-154 536.00
IUUC-Meu-056307 Macropus eugenii 51.35 8.00e-137 479.00
IUUC-Mor-057171 Magnaporthe oryzae 38.65 4.00e-63 234.00
IUUC-Mpo-057415 Magnaporthe poae 37.53 1.00e-64 239.00
IUUC-Mtr-057901 Medicago truncatula 39.59 4.00e-96 344.00
IUUC-Mla-058897 Melampsora laricipopulina 36.07 6.00e-68 251.00
IUUC-Mga-060016 Meleagris gallopavo 54.89 6.00e-152 529.00
IUUC-Mvi-060562 Microbotryum violaceum 35.77 7.00e-59 220.00
IUUC-Mmr-060624 Microcebus murinus 55.76 1.00e-160 558.00
IUUC-Mdo-061809 Monodelphis domestica 54.71 5.00e-153 533.00
IUUC-Mmu-063869 Mus musculus 56.06 2.00e-156 545.00
IUUC-Mac-064876 Musa acuminata 35.25 6.00e-82 297.00
IUUC-Mpu-066480 Mustela putorius furo 55.56 5.00e-157 546.00
IUUC-Mlu-067866 Myotis lucifugus 55.35 2.00e-156 544.00
IUUC-Nfi-068393 Neosartorya fischeri 36.80 1.00e-57 216.00
IUUC-Ncr-068815 Neurospora crassa 35.20 1.00e-58 219.00
IUUC-Nle-070121 Nomascus leucogenys 50.79 1.00e-70 258.00
IUUC-Opr-070712 Ochotona princeps 43.57 1.00e-91 330.00
IUUC-Ont-071544 Oreochromis niloticus 55.83 9.00e-144 502.00
IUUC-Oan-073635 Ornithorhynchus anatinus 53.24 6.00e-124 436.00
IUUC-Ocu-074926 Oryctolagus cuniculus 54.64 4.00e-154 536.00
IUUC-Oba-075633 Oryza barthii 38.74 6.00e-93 333.00
IUUC-Obr-076423 Oryza brachyantha 39.88 3.00e-95 341.00
IUUC-Ogl-077913 Oryza glaberrima 39.46 3.00e-94 338.00
IUUC-Ogu-078435 Oryza glumaepatula 38.74 6.00e-93 333.00
IUUC-Oin-080072 Oryza indica 38.94 8.00e-93 333.00
IUUC-Olo-080535 Oryza longistaminata 35.92 1.00e-76 279.00
IUUC-Ome-081309 Oryza meridionalis 38.74 6.00e-93 333.00
IUUC-Oni-083113 Oryza nivara 38.74 6.00e-93 333.00
IUUC-Opu-083168 Oryza punctata 37.63 9.00e-89 319.00
IUUC-Oru-084253 Oryza rufipogon 38.74 6.00e-93 333.00
IUUC-Osa-085554 Oryza sativa 39.46 2.00e-94 338.00
IUUC-Ola-086998 Oryzias latipes 55.19 4.00e-152 530.00
IUUC-Olu-087818 Ostreococcus lucimarinus 34.65 7.00e-63 233.00
IUUC-Oga-088571 Otolemur garnettii 56.08 8.00e-158 549.00
IUUC-Oar-089526 Ovis aries 55.28 3.00e-154 537.00
IUUC-Ptr-091433 Pan troglodytes 55.35 4.00e-154 536.00
IUUC-Pan-091966 Papio anubis 55.35 4.00e-154 536.00
IUUC-Psi-093458 Pelodiscus sinensis 55.02 3.00e-148 517.00
IUUC-Pma-094343 Petromyzon marinus 52.10 7.00e-83 299.00
IUUC-Pno-095109 Phaeosphaeria nodorum 39.45 4.00e-65 241.00
IUUC-Ppa-095756 Physcomitrella patens 37.63 1.00e-90 325.00
IUUC-Pfo-096514 Poecilia formosa 56.03 2.00e-147 514.00
IUUC-Pab-098477 Pongo abelii 49.14 7.00e-116 409.00
IUUC-Pop-099221 Populus trichocarpa 36.49 8.00e-86 310.00
IUUC-Pca-100791 Procavia capensis 47.02 2.00e-97 348.00
IUUC-Ppe-101812 Prunus persica 37.60 2.00e-88 318.00
IUUC-Pva-102462 Pteropus vampyrus 52.73 4.00e-126 443.00
IUUC-Pgr-103623 Puccinia graminis 35.91 3.00e-63 235.00
IUUC-Ptt-103767 Puccinia triticina 35.19 2.00e-58 219.00
IUUC-Pte-104109 Pyrenophora teres 38.93 2.00e-68 252.00
IUUC-Pyt-104766 Pyrenophora triticirepentis 39.73 1.00e-69 256.00
IUUC-Rno-105351 Rattus norvegicus 55.76 3.00e-154 537.00
IUUC-Sce-106168 Saccharomyces cerevisiae 30.45 1.00e-54 206.00
IUUC-Sha-107491 Sarcophilus harrisii 55.44 4.00e-155 540.00
IUUC-Sja-107769 Schizosaccharomyces japonicus 35.92 5.00e-86 310.00
IUUC-Spo-108174 Schizosaccharomyces pombe 37.89 3.00e-80 291.00
IUUC-Ssl-108659 Sclerotinia sclerotiorum 32.58 1.00e-73 270.00
IUUC-Smo-108805 Selaginella moellendorffii 40.21 9.00e-99 353.00
IUUC-Sit-110361 Setaria italica 37.70 4.00e-95 341.00
IUUC-Sly-110965 Solanum lycopersicum 36.34 9.00e-88 316.00
IUUC-Sar-113355 Sorex araneus 50.48 6.00e-86 310.00
IUUC-Sbi-114778 Sorghum bicolor 39.34 8.00e-94 336.00
IUUC-Sre-115011 Sporisorium reilianum 35.51 5.00e-58 218.00
IUUC-Ssc-116273 Sus scrofa 55.07 5.00e-152 530.00
IUUC-Tgu-117063 Taeniopygia guttata 54.77 2.00e-150 524.00
IUUC-Tru-118381 Takifugu rubripes 55.10 1.00e-151 528.00
IUUC-Tsy-119076 Tarsius syrichta 53.47 1.00e-71 262.00
IUUC-Tni-119941 Tetraodon nigroviridis 56.88 8.00e-150 522.00
IUUC-Tca-121246 Theobroma cacao 38.62 2.00e-91 328.00
IUUC-Tre-121969 Trichoderma reesei 35.68 7.00e-64 237.00
IUUC-Tvi-122543 Trichoderma virens 32.55 1.00e-73 270.00
IUUC-Tae-125484 Triticum aestivum 39.67 2.00e-93 335.00
IUUC-Tur-126128 Triticum urartu 31.53 5.00e-35 141.00
IUUC-Tbe-128030 Tupaia belangeri 49.69 2.00e-131 461.00
IUUC-Ttr-128701 Tursiops truncatus 53.48 7.00e-123 432.00
IUUC-Uma-129657 Ustilago maydis 36.16 2.00e-60 225.00
IUUC-Vda-129723 Verticillium dahliae 33.42 2.00e-55 209.00
IUUC-Vpa-130284 Vicugna pacos 38.20 3.00e-86 311.00
IUUC-Vvi-131037 Vitis vinifera 38.00 2.00e-91 328.00
IUUC-Xtr-132235 Xenopus tropicalis 55.14 6.00e-157 546.00
IUUC-Xma-133840 Xiphophorus maculatus 56.24 2.00e-154 538.00
IUUC-Yli-134453 Yarrowia lipolytica 35.03 1.00e-79 289.00
IUUC-Zma-135669 Zea mays 32.24 2.00e-76 279.00
Created Date 25-Jun-2017

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