iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027961

Ensembl Protein ID

ENSDARP00000140771.1

UniProt Accession

F1R4W4; F1R4W4_DANRE

Genbank Protein ID

ENSDARP00000060970

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

CU929326

Gene Name

dcun1d2b; dcun1d2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000041592.5	ENSDART00000166956.1	ENSDARP00000140771.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.50e-84	283.7	5	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 1    vskkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktlesel 88
           v+++kl  l++rYkdpq++ +ig++g+++fc+dl +dp++++vL++awk++aat+cefsr+efldg+t lgcds ekl+  l++le+el
   Q: 5    VDRRKLDLLYSRYKDPQDEnKIGVDGIQQFCDDLMLDPASVSVLIVAWKFRAATQCEFSRQEFLDGMTDLGCDSPEKLKSLLPRLEQEL 93
           5789*************999********************************************************************* PP
   S: 89   kdeqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaW 177
           kd  kf+d+Yrf+f+fak +gqk ldl++a+a+w+L+l++r fk+l +w++fL e++kksi+kDtWnllL+f ++ia+d+snYdeegaW
   Q: 94   KDSGKFRDFYRFTFSFAKSPGQKCLDLEMAVAYWNLILSGR-FKFLGLWNTFLLEHHKKSIPKDTWNLLLDFGNMIADDMSNYDEEGAW 181
           ****************************************9.*********************************************** PP
   S: 178  PvliDefveyl 188
           PvliD+fve++
   Q: 182  PVLIDDFVEFA 192
           *********97 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MKTAVDRRKL DLLYSRYKDP QDENKIGVDG IQQFCDDLML DPASVSVLIV AWKFRAATQC 60
EFSRQEFLDG MTDLGCDSPE KLKSLLPRLE QELKDSGKFR DFYRFTFSFA KSPGQKCLDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACACACCGCG ACTCCCGAAC CGGAGAGAGA GACGGAGACC CGCTGCTCTG AGAGAAACAA 60
CCGGAGAGAG AGACACTCGG AGCAGGAGAA GGTAACTGAG ACACATGATG ATGATCATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cfa-020152	Canis familiaris	83.33	3.00e-101	360.00
IUUC-Cho-024417	Choloepus hoffmanni	82.70	4.00e-91	327.00
IUUC-Fca-035856	Felis catus	82.32	3.00e-101	360.00
IUUC-Pyt-104428	Pyrenophora triticirepentis	31.55	1.00e-28	120.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence