iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aly-006427

UUCD1 version

UUC-ArL-01271

Ensembl Protein ID

fgenesh2_kg.6__604__AT5G06600.1

UniProt Accession

D7LZS2; D7LZS2_ARALL

Genbank Protein ID

EFH49528.1

Protein Name

Ubiquitin-specific protease 12

Genbank Nucleotide ID

GL348718

Gene Name

UBP12; ARALYDRAFT_487470

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.6__604__AT5G06600.1	fgenesh2_kg.6__604__AT5G06600.1	fgenesh2_kg.6__604__AT5G06600.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-70	238.1	199	522

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           +GlkN+g+tCYmNS+LQ+L++ip +r+++ +     ++ ++++ p++++  +lq+lf +l ++++++v+++el+k+++
   Q: 199  VGLKNQGATCYMNSLLQTLYHIPYFRKAVYH-----MPTTENDLPTASIPLALQSLFYKL-QYNDTSVATKELTKSFG 270
           6******************************.....4444556799**************.88999************ PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikc 156
           +    +++++q+D+qE+ ++l ++le+++                          k +  + +i++lF+g+  + i c
   Q: 271  WDT--YDSFMQHDVQELNRVLCEKLEDKM--------------------------KGTVVEGTIQQLFEGHHMNYIEC 320
           877..67**********************..........................7899******************* PP
   S: 157  lecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhL 234
            + d +s+r+e+f+dl+l+v+g +     ++  +++++++ e+leg+nky+ e   ++q+a+k + +  +P+vL l+L
   Q: 321  INVDFKSTRKESFYDLQLDVKGCK-----DVYASFDKYVEVERLEGDNKYHAEGH-GLQDAKKGVLFIDFPPVLQLQL 392
           ************************.....9*********************9985.79******************** PP
   S: 235  kRfsfseeqksrekinkkvefpleLdls....pfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWl 307
           kRf+++  ++   kin+++efpleLdl+    ++++ p+ + ++++ Y L++v+vHsG++++GHY+a+++   +++W+
   Q: 393  KRFEYDFMRDTMVKINDRYEFPLELDLDrengKYLS-PDADRSVRNLYTLHSVLVHSGGVHGGHYYAFIRPtLSDQWY 469
           ***************************955544554.5666678**************************945677** PP
   S: 308  lfdDskVtevkeeevleetg.......................staYvlfYkr 337
           +fdD++Vt+ + ++ lee+                        s+aY+l+Y r
   Q: 470  KFDDERVTKEDLKRALEEQYggeeelpqtnpgfnnppfkftkySNAYMLVYIR 522
           ***********9999997779******************************87 PP

Organism

Arabidopsis lyrata

Protein Sequence
(Fasta)

MTMMTPPPVD QPEDEEMLVP NSDLVDGPAQ PMEVIQPETA ASTVENQPAE DPPTLKFTWT 60
IPNFSRQNTR KHYSDVFVVG GYKWRILIFP KGNNVDHLSM YLDVSDAASL PYGWSRYAQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTGTATTT CTCCCTAGAG TCACTTTGCC TCTTCTTTGA TTTTTCTCTG CATCGTCGGT 60
CTCTCTTTTG CGTTTCTCGA TCCCACCGTC AAATCCTTCT CCGGCCAATG ACTATGATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_487470

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	76.15	0.00e+00	1699.00
IUUC-Atr-003067	Amborella trichopoda	85.55	0.00e+00	1482.00
IUUC-Ath-006591	Arabidopsis thaliana	98.84	0.00e+00	2176.00
IUUC-Aor-009998	Aspergillus oryzae	37.63	6.00e-177	614.00
IUUC-Ate-010428	Aspergillus terreus	38.21	3.00e-180	625.00
IUUC-Ame-010903	Astyanax mexicanus	35.41	2.00e-165	576.00
IUUC-Bdi-015069	Brachypodium distachyon	81.95	0.00e+00	1816.00
IUUC-Bol-015621	Brassica oleracea	95.48	0.00e+00	2128.00
IUUC-Bra-017080	Brassica rapa	95.07	0.00e+00	2137.00
IUUC-Cel-018219	Caenorhabditis elegans	28.23	6.00e-101	361.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	55.78	6.00e-143	499.00
IUUC-Csa-024050	Chlorocebus sabaeus	35.80	5.00e-165	574.00
IUUC-Cho-024434	Choloepus hoffmanni	31.37	2.00e-86	313.00
IUUC-Cne-026968	Cryptococcus neoformans	41.85	0.00e+00	733.00
IUUC-Cme-027103	Cyanidioschyzon merolae	39.15	2.00e-128	453.00
IUUC-Dre-028510	Danio rerio	35.50	4.00e-166	578.00
IUUC-Dse-031433	Dothistroma septosporum	36.08	5.00e-171	594.00
IUUC-Gmo-038644	Gadus morhua	35.01	3.00e-167	582.00
IUUC-Gma-043081	Glycine max	83.29	0.00e+00	1873.00
IUUC-Hsa-046278	Homo sapiens	35.80	5.00e-165	574.00
IUUC-Hvu-047749	Hordeum vulgare	81.64	0.00e+00	1534.00
IUUC-Kpa-049121	Komagataella pastoris	31.69	4.00e-134	471.00
IUUC-Lch-049847	Latimeria chalumnae	35.71	3.00e-169	588.00
IUUC-Lpe-051543	Leersia perrieri	80.18	0.00e+00	1754.00
IUUC-Loc-052234	Lepisosteus oculatus	38.28	5.00e-133	468.00
IUUC-Lma-053169	Leptosphaeria maculans	38.66	6.00e-177	614.00
IUUC-Mtr-058583	Medicago truncatula	82.86	0.00e+00	1865.00
IUUC-Mla-058899	Melampsora laricipopulina	38.68	0.00e+00	689.00
IUUC-Mvi-060207	Microbotryum violaceum	38.43	0.00e+00	678.00
IUUC-Mmr-060946	Microcebus murinus	35.80	6.00e-165	574.00
IUUC-Mac-064796	Musa acuminata	83.47	0.00e+00	1858.00
IUUC-Nfi-068342	Neosartorya fischeri	39.05	2.00e-175	609.00
IUUC-Nle-070064	Nomascus leucogenys	35.80	5.00e-165	574.00
IUUC-Ont-072095	Oreochromis niloticus	35.14	2.00e-166	579.00
IUUC-Oba-075823	Oryza barthii	78.66	0.00e+00	1722.00
IUUC-Obr-076514	Oryza brachyantha	83.16	0.00e+00	1817.00
IUUC-Ogl-077131	Oryza glaberrima	83.14	0.00e+00	1805.00
IUUC-Ogu-078038	Oryza glumaepatula	77.37	0.00e+00	1744.00
IUUC-Oin-079574	Oryza indica	77.59	0.00e+00	1749.00
IUUC-Olo-081067	Oryza longistaminata	79.22	0.00e+00	1673.00
IUUC-Ome-081879	Oryza meridionalis	82.34	0.00e+00	1798.00
IUUC-Oni-082461	Oryza nivara	79.34	0.00e+00	1768.00
IUUC-Opu-083199	Oryza punctata	81.60	0.00e+00	1759.00
IUUC-Oru-085109	Oryza rufipogon	80.53	0.00e+00	1736.00
IUUC-Osa-085418	Oryza sativa	69.77	0.00e+00	1306.00
IUUC-Olu-087874	Ostreococcus lucimarinus	45.43	0.00e+00	906.00
IUUC-Oga-089059	Otolemur garnettii	33.72	2.00e-141	496.00
IUUC-Pma-094648	Petromyzon marinus	37.82	1.00e-159	556.00
IUUC-Pno-095020	Phaeosphaeria nodorum	37.28	7.00e-165	574.00
IUUC-Ppa-095922	Physcomitrella patens	79.09	0.00e+00	1781.00
IUUC-Pfo-096181	Poecilia formosa	35.23	4.00e-166	578.00
IUUC-Pop-100083	Populus trichocarpa	87.38	0.00e+00	1955.00
IUUC-Ppe-101523	Prunus persica	87.20	0.00e+00	1922.00
IUUC-Pva-102472	Pteropus vampyrus	36.37	6.00e-160	557.00
IUUC-Pgr-103463	Puccinia graminis	39.89	0.00e+00	687.00
IUUC-Ptt-103716	Puccinia triticina	39.11	0.00e+00	634.00
IUUC-Pte-104360	Pyrenophora teres	38.17	2.00e-173	602.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	37.25	9.00e-174	603.00
IUUC-Rno-105816	Rattus norvegicus	35.89	5.00e-165	574.00
IUUC-Sce-106230	Saccharomyces cerevisiae	33.96	1.00e-128	453.00
IUUC-Spo-108019	Schizosaccharomyces pombe	36.77	1.00e-153	536.00
IUUC-Smo-109308	Selaginella moellendorffii	78.71	0.00e+00	1754.00
IUUC-Sit-110268	Setaria italica	82.44	0.00e+00	1804.00
IUUC-Sly-111774	Solanum lycopersicum	82.77	0.00e+00	1868.00
IUUC-Stu-112387	Solanum tuberosum	82.95	0.00e+00	1878.00
IUUC-Sbi-114424	Sorghum bicolor	82.53	0.00e+00	1822.00
IUUC-Ssc-116297	Sus scrofa	35.80	2.00e-164	573.00
IUUC-Tca-121501	Theobroma cacao	87.92	0.00e+00	1961.00
IUUC-Tae-123032	Triticum aestivum	81.34	0.00e+00	1828.00
IUUC-Tur-126501	Triticum urartu	72.65	0.00e+00	1587.00
IUUC-Tme-127045	Tuber melanosporum	37.34	2.00e-177	615.00
IUUC-Ttr-129161	Tursiops truncatus	35.79	2.00e-163	569.00
IUUC-Vvi-131308	Vitis vinifera	86.58	0.00e+00	1934.00
IUUC-Xma-133949	Xiphophorus maculatus	35.38	3.00e-165	575.00
IUUC-Yli-134527	Yarrowia lipolytica	34.04	1.00e-151	530.00
IUUC-Zma-135855	Zea mays	78.79	0.00e+00	1737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence